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FI922847L - Antikroppsantagonister foer human interleukin-4. - Google Patents

Antikroppsantagonister foer human interleukin-4. Download PDF

Info

Publication number
FI922847L
FI922847L FI922847A FI922847A FI922847L FI 922847 L FI922847 L FI 922847L FI 922847 A FI922847 A FI 922847A FI 922847 A FI922847 A FI 922847A FI 922847 L FI922847 L FI 922847L
Authority
FI
Finland
Prior art keywords
antagonister
foer
antibody
human interleukin
interleukin
Prior art date
Application number
FI922847A
Other languages
English (en)
Other versions
FI104180B1 (fi
FI922847A0 (fi
FI104180B (fi
Inventor
Lata Ramanathan
Gail F Seelig
Paul P Trotta
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI922847A0 publication Critical patent/FI922847A0/fi
Publication of FI922847L publication Critical patent/FI922847L/fi
Application granted granted Critical
Publication of FI104180B1 publication Critical patent/FI104180B1/fi
Publication of FI104180B publication Critical patent/FI104180B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/247—IL-4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5406—IL-4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI922847A 1989-12-20 1992-06-18 Menetelmä polypeptidin vasta-aineen ekä IL-4 välittämien tilojen hoitoon tarkoitetun seoksen valmistamiseksi FI104180B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45357089A 1989-12-20 1989-12-20
US45357089 1989-12-20
US9007289 1990-12-18
PCT/US1990/007289 WO1991009059A1 (en) 1989-12-20 1990-12-18 Antibody antagonists of human interleukin-4

Publications (4)

Publication Number Publication Date
FI922847A0 FI922847A0 (fi) 1992-06-18
FI922847L true FI922847L (fi) 1992-06-18
FI104180B1 FI104180B1 (fi) 1999-11-30
FI104180B FI104180B (fi) 1999-11-30

Family

ID=23801108

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922847A FI104180B (fi) 1989-12-20 1992-06-18 Menetelmä polypeptidin vasta-aineen ekä IL-4 välittämien tilojen hoitoon tarkoitetun seoksen valmistamiseksi

Country Status (26)

Country Link
US (1) US6358509B1 (fi)
EP (1) EP0506826B1 (fi)
JP (1) JPH0730116B2 (fi)
KR (1) KR960016862B1 (fi)
AT (1) ATE136906T1 (fi)
AU (1) AU639754B2 (fi)
CA (1) CA2071908C (fi)
CZ (1) CZ283050B6 (fi)
DE (1) DE69026627T2 (fi)
DK (1) DK0506826T3 (fi)
ES (1) ES2085983T3 (fi)
FI (1) FI104180B (fi)
GR (1) GR3020325T3 (fi)
HU (1) HU215245B (fi)
IE (1) IE74708B1 (fi)
IL (1) IL96714A0 (fi)
MX (1) MX9203401A (fi)
MY (1) MY106507A (fi)
NO (1) NO922457D0 (fi)
NZ (1) NZ236511A (fi)
OA (1) OA09704A (fi)
PT (1) PT96230B (fi)
SK (1) SK279933B6 (fi)
TW (1) TW221675B (fi)
WO (1) WO1991009059A1 (fi)
ZA (1) ZA9010190B (fi)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714146A (en) * 1992-08-26 1998-02-03 Board Of Regents Of The University Of Washington IL-4 bone therapy
ZA946765B (en) 1993-09-02 1996-02-15 Dartmouth College Methods of prolonged suppression of humoral immunity
US20020193575A1 (en) 1993-09-07 2002-12-19 Smithkline Beecham P.L.C. Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
DE69434223T2 (de) * 1993-09-07 2005-12-22 Smithkline Beecham P.L.C., Brentford In der Behandlung von IL4 auslösenden Krankheiten nützliche rekombinante IL4-Antikörper
US5914110A (en) * 1993-09-07 1999-06-22 Smithkline Beecham Corporation Recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US5928904A (en) * 1993-09-07 1999-07-27 Smithkline Beecham Corporation DNA encoding recombinant IL4 antibodies useful in treatment of IL4 mediated disorders
US5597710A (en) * 1994-03-10 1997-01-28 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
US5705154A (en) * 1995-03-08 1998-01-06 Schering Corporation Humanized monoclonal antibodies against human interleukin-4
CA2252790A1 (en) * 1997-02-28 1998-09-03 Enzo Therapeutics, Inc. Novel processes implementing selective immune down regulation (sidr)
DE69933696T2 (de) 1998-12-14 2007-08-23 Genetics Institute, LLC, Cambridge Cytokinrezeptor-kette
US7553487B2 (en) 1998-12-14 2009-06-30 Genetics Institute, Llc Method and compositions for treating asthma
DE60135170D1 (de) * 2000-04-06 2008-09-18 Fujifilm Corp Farbstoffkomplex und optisches Informationsaufzeichnungsmedium
EP2292665B1 (en) 2000-05-26 2015-07-08 Immunex Corporation Use of interleukin-4 antibodies and compositions thereof
AU2001273413A1 (en) * 2000-07-12 2002-01-21 Immunex Corporation Method for treating cancer using an interleukin- 4 antagonist
US20030170258A1 (en) * 2001-05-09 2003-09-11 Enzo Therapeutics, Inc. Novel processes implementing selective immune down regulation (SIDR)
FR2838444B1 (fr) 2002-04-10 2016-01-01 Neovacs Nouveaux peptides et leur application en therapeutique
US20070104710A1 (en) * 2002-06-28 2007-05-10 Domants Limited Ligand that has binding specificity for IL-4 and/or IL-13
WO2004003156A2 (en) * 2002-07-01 2004-01-08 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Il-21 as a regulator of immunoglobin production
US20110223168A1 (en) * 2002-12-27 2011-09-15 Greg Winter Ligand that has binding specificity for il-4 and/or il-13
WO2004096849A2 (en) * 2003-04-25 2004-11-11 University Of Manitoba Peptide-based cytokine/chemokine vaccines against allergy
MXPA06004853A (es) 2003-11-07 2006-07-06 Immunex Corp Anticuerpos que se aglutinan al receptor 4 de interleucina.
CA2551110C (en) 2003-12-23 2016-01-19 Tanox, Inc. Treatment of cancer with novel anti-il 13 monoclonal antibodies
AR049390A1 (es) 2004-06-09 2006-07-26 Wyeth Corp Anticuerpos contra la interleuquina-13 humana y usos de los mismos
US7501121B2 (en) 2004-06-17 2009-03-10 Wyeth IL-13 binding agents
PE20060560A1 (es) * 2004-08-03 2006-06-27 Novartis Ag Anticuerpos de interleucina-4 humana
JP5750373B2 (ja) * 2008-11-17 2015-07-22 コーベンハブンス ウニベルシテト 慢性炎症性応答の調節および自己免疫疾患の処置のためのｉｌ−４由来ペプチド
WO2011133886A2 (en) 2010-04-23 2011-10-27 Genentech, Inc. Production of heteromultimeric proteins
MX355255B (es) 2011-02-04 2018-04-11 Genentech Inc Variantes de fc y métodos para su producción.
US10689447B2 (en) 2011-02-04 2020-06-23 Genentech, Inc. Fc variants and methods for their production
EP2981286A4 (en) * 2013-04-05 2016-08-24 Hoffmann La Roche ANTI-IL-4 ANTIBODIES AND BISPECIFIC ANTIBODIES AND USES THEREOF
EP3683232A1 (en) 2013-09-13 2020-07-22 F. Hoffmann-La Roche AG Methods and compositions comprising purified recombinant polypeptides
MX2016002799A (es) 2013-09-13 2016-05-26 Genentech Inc Composiciones y metodos para detectar y cuantificar la proteina en la celula hospedera en las lineas de celulas y productos de polipeptidos recombinantes.
CA2943707A1 (en) 2014-05-06 2015-11-12 Genentech, Inc. Production of heteromultimeric proteins using mammalian cells
KR102652133B1 (ko) * 2018-02-01 2024-03-29 베이징 카윈 테크놀로지 쉐어-홀딩 컴퍼니 리미티드 IL-4Rα 항체 및 그 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013824A (en) * 1985-11-19 1991-05-07 Schering Corporation Human interleukin-4 peptides and conjugates thereof
PT83761B (pt) * 1985-11-19 1989-06-30 Schering Biotech Corp Metodo para a producao de interleuquina-4 de mamifero
US5041381A (en) * 1986-07-03 1991-08-20 Schering Corporation Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
ZA872781B (en) 1986-05-19 1987-10-05 Immunology Ventures B-cell stimulating factor
ATE93144T1 (de) * 1988-02-02 1993-09-15 Schering Biotech Corp Methode zur verminderung der immunglobulin-ereaktion.

Also Published As

Publication number Publication date
WO1991009059A1 (en) 1991-06-27
KR960016862B1 (ko) 1996-12-23
HU215245B (hu) 1998-11-30
TW221675B (fi) 1994-03-11
KR920703642A (ko) 1992-12-18
SK635290A3 (en) 1999-06-11
FI104180B1 (fi) 1999-11-30
US6358509B1 (en) 2002-03-19
PT96230A (pt) 1991-10-15
NZ236511A (en) 1993-02-25
SK279933B6 (sk) 1999-06-11
CZ635290A3 (en) 1997-08-13
JPH04506359A (ja) 1992-11-05
AU7176291A (en) 1991-07-18
DE69026627T2 (de) 1996-08-22
HU9202073D0 (en) 1992-09-28
AU639754B2 (en) 1993-08-05
NO922457L (no) 1992-06-19
MX9203401A (es) 1992-07-01
FI922847A0 (fi) 1992-06-18
CA2071908C (en) 2002-04-30
CA2071908A1 (en) 1991-06-21
ATE136906T1 (de) 1996-05-15
ZA9010190B (en) 1991-08-28
HUT64568A (en) 1994-01-28
PT96230B (pt) 1998-06-30
DK0506826T3 (da) 1996-05-13
IE904589A1 (en) 1991-07-03
GR3020325T3 (en) 1996-09-30
CZ283050B6 (cs) 1997-12-17
EP0506826A1 (en) 1992-10-07
OA09704A (en) 1993-08-30
NO922457D0 (no) 1992-06-19
ES2085983T3 (es) 1996-06-16
JPH0730116B2 (ja) 1995-04-05
IL96714A0 (en) 1991-09-16
DE69026627D1 (de) 1996-05-23
EP0506826B1 (en) 1996-04-17
IE74708B1 (en) 1997-07-30
MY106507A (en) 1995-06-30
FI104180B (fi) 1999-11-30

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