FI922827A - Imidazodiazepiner - Google Patents

Imidazodiazepiner Download PDF

Info

Publication number: FI922827A
Authority: FI; Finland
Prior art keywords: imidazodiazepiner
Prior art date: 1991-06-17

Application number

FI922827A

Other languages

English (en)

Finnish (fi)

Other versions

FI922827A0 (fi

Inventor

Rene Borer

Walter Gassner

Max Gerecke

Emilio Kyburz

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-17

Filing date

1992-06-17

Publication date

1992-12-18

1992-06-17 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1992-06-17 Publication of FI922827A0 publication Critical patent/FI922827A0/fi

1992-12-18 Publication of FI922827A publication Critical patent/FI922827A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

FI922827A 1991-06-17 1992-06-17 Imidazodiazepiner FI922827A (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH179191		1991-06-17
CH114092		1992-04-08

Publications (2)

Publication Number	Publication Date
FI922827A0 FI922827A0 (fi)	1992-06-17
FI922827A true FI922827A (fi)	1992-12-18

Family

ID=25686778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI922827A FI922827A (fi)	1991-06-17	1992-06-17	Imidazodiazepiner

Country Status (15)

Country	Link
US (1)	US5387585A (sl)
EP (1)	EP0519307A3 (sl)
JP (1)	JPH078869B2 (sl)
KR (1)	KR930000517A (sl)
AU (1)	AU655472B2 (sl)
CA (1)	CA2069382A1 (sl)
CZ (1)	CZ185092A3 (sl)
FI (1)	FI922827A (sl)
HU (1)	HU9201929D0 (sl)
IE (1)	IE921945A1 (sl)
IL (1)	IL102175A0 (sl)
IS (1)	IS3878A (sl)
NO (1)	NO922367L (sl)
NZ (1)	NZ243091A (sl)
TW (1)	TW201311B (sl)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW349100B (en) *	1994-11-11	1999-01-01	Hoffmann La Roche	Oxazolyl- and thiazolylimidazo-benzo- and thienodiazepines
JPH10298078A (ja) *	1997-05-06	1998-11-10	Mitsubishi Chem Corp	抗不安薬
TWI239333B (en) *	2000-11-16	2005-09-11	Hoffmann La Roche	Benzodiazepine derivatives as GABA A receptor modulators
US6686352B2 (en)	2001-05-18	2004-02-03	Hoffmann-La Roche Inc.	Substituted imidazo [1,5-a] pyrimido [5,4-d] [1] benzazepine derivatives
WO2002100341A2 (en) *	2001-06-12	2002-12-19	Wellstat Therapeutics Corporation	Compounds for the treatment of metabolic disorders
CA2581918A1 (en) *	2004-10-12	2006-04-20	Henner Knust	Imidazo(1,5-a)triazolo(1,5-d) benzodiazepine deratives for the treatment of cognitive disorders
MX2007004639A (es) *	2004-10-20	2007-06-08	Hoffmann La Roche	Derivados de imidazo-benzodiazepina.
MX2007004640A (es) *	2004-10-20	2007-06-08	Hoffmann La Roche	Derivados de benzodiazepina sustituidos con halogeno.
RU2393161C2 (ru) *	2004-12-14	2010-06-27	Ф. Хоффманн-Ля Рош Аг	Тетрациклические имидазо-бензодиазепины в качестве модуляторов гамк-рецепторов
AU2006301377B2 (en) *	2005-10-11	2012-03-08	F. Hoffmann-La Roche Ag	Imidazo benzodiazepine derivatives
AU2014240289B2 (en) *	2008-09-23	2015-12-03	The Johns Hopkins University	Fused diimidazodiazepine compounds and methods of use and manufacture thereof
AU2009300357B2 (en) *	2008-09-23	2014-07-03	The Johns Hopkins University	Fused diimidazodiazepine compounds and methods of use and manufacture thereof
US9322831B2 (en)	2008-09-23	2016-04-26	The Johns Hopkins University	DDX3 as a biomarker for cancer and methods related thereto
NO3034079T3 (sl)	2010-11-15	2018-06-09
PL3041827T3 (pl)	2013-09-06	2018-09-28	Aurigene Discovery Tech Limited	Pochodne 1,2,4-oksadiazolu jako immunomodulatory
AU2014368961B2 (en)	2013-12-20	2019-10-17	Agenebio, Inc.	Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
WO2016142886A2 (en) *	2015-03-10	2016-09-15	Aurigene Discovery Technologies Limited	3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators
RS62960B1 (sr)	2015-03-10	2022-03-31	Aurigene Discovery Tech Ltd	Jedinjenja 1,2,4-oksadiazola i tiadiazola kao imunomodulatori
WO2016205739A1 (en) *	2015-06-19	2016-12-22	Belew Mekonnen	Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
US10221191B2 (en)	2015-12-22	2019-03-05	SHY Therapeutics LLC	Compounds for the treatment of cancer and inflammatory disease
US20180170941A1 (en) *	2016-12-19	2018-06-21	Agenebio, Inc.	Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
US11505555B2 (en)	2016-12-19	2022-11-22	Agenebio, Inc.	Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment
SG11201911929XA (en)	2017-06-21	2020-01-30	SHY Therapeutics LLC	Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
WO2019061324A1 (en)	2017-09-29	2019-04-04	Curis Inc.	CRYSTALLINE FORMS OF IMMUNOMODULATORS
BR112020006669A2 (pt)	2017-10-11	2020-09-24	Aurigene Discovery Technologies Limited	formas cristalinas de 1,2,4-oxadiazol 3-substituído
SG11202003625VA (en)	2017-11-03	2020-05-28	Aurigene Discovery Tech Ltd	Dual inhibitors of tim-3 and pd-1 pathways
KR20200084333A (ko)	2017-11-06	2020-07-10	오리진 디스커버리 테크놀로지스 리미티드	면역조절을 위한 병행 요법
WO2019246300A1 (en)	2018-06-19	2019-12-26	Agenebio, Inc.	Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1143728A (en) *	1979-10-04	1983-03-29	Max Gerecke	Imidazodiazepine derivatives
DE3587913D1 (de) *	1984-01-19	1994-10-06	Hoffmann La Roche	Imidazodiazepin-Derivate.
US4897392A (en) *	1989-07-03	1990-01-30	Hoechst-Roussel Pharmaceuticals, Inc.	4H-indolo(1,2-d)(1,2,4)triazolo(4,3-A)(1,4)benzodiazepines
DK443589D0 (da) *	1989-09-08	1989-09-08	Ferrosan As	Heterocykliske forbindelser, deres fremstilling og anvendelse
DK41191D0 (da) *	1991-03-07	1991-03-07	Novo Nordisk As	Heterocycliske forbindelser, deres fremstilling og anvendelse

1992
- 1992-05-15 TW TW081103807A patent/TW201311B/zh active
- 1992-05-25 CA CA002069382A patent/CA2069382A1/en not_active Abandoned
- 1992-06-10 NZ NZ243091A patent/NZ243091A/en unknown
- 1992-06-10 HU HU9201929A patent/HU9201929D0/hu unknown
- 1992-06-10 EP EP19920109745 patent/EP0519307A3/de not_active Withdrawn
- 1992-06-11 IL IL102175A patent/IL102175A0/xx unknown
- 1992-06-12 IS IS3878A patent/IS3878A/is unknown
- 1992-06-12 AU AU18234/92A patent/AU655472B2/en not_active Ceased
- 1992-06-12 JP JP4179406A patent/JPH078869B2/ja not_active Expired - Lifetime
- 1992-06-16 CZ CS921850A patent/CZ185092A3/cs unknown
- 1992-06-16 KR KR1019920010394A patent/KR930000517A/ko not_active Application Discontinuation
- 1992-06-16 NO NO92922367A patent/NO922367L/no unknown
- 1992-06-17 FI FI922827A patent/FI922827A/fi not_active Application Discontinuation
- 1992-07-01 IE IE194592A patent/IE921945A1/en not_active Application Discontinuation
1993
- 1993-11-15 US US08/153,234 patent/US5387585A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5387585A (en)	1995-02-07
IE921945A1 (en)	1992-12-30
FI922827A0 (fi)	1992-06-17
KR930000517A (ko)	1993-01-15
JPH05202051A (ja)	1993-08-10
NZ243091A (en)	1994-11-25
CZ185092A3 (en)	1993-12-15
EP0519307A3 (en)	1993-04-21
AU1823492A (en)	1992-12-24
CA2069382A1 (en)	1992-12-18
JPH078869B2 (ja)	1995-02-01
NO922367D0 (no)	1992-06-16
EP0519307A2 (de)	1992-12-23
NO922367L (no)	1992-12-18
TW201311B (sl)	1993-03-01
HU9201929D0 (en)	1992-08-28
IL102175A0 (en)	1993-01-14
AU655472B2 (en)	1994-12-22
IS3878A (is)	1992-12-18

Publication	Publication Date	Title
DE69133396D1 (de)	2004-07-22	Warenauszahlsystem
DE69212332D1 (de)	1996-08-22	Farbball
DE59206583D1 (de)	1996-07-18	Windsichter
DE69219551D1 (de)	1997-06-12	Überrahmen
ATE137279T1 (de)	1996-05-15	Stoffauflauf
DE59209950D1 (de)	2002-05-16	Flaschendispenser
DE69218585D1 (de)	1997-04-30	Anzeigetafel
DE69219252D1 (de)	1997-05-28	Ölbehälter
ATA131391A (de)	1992-09-15	Reibring
BR9204511A (pt)	1993-06-01	Recolhedor-enrolador
DE59208716D1 (de)	1997-08-21	Lymphoides cd30-antigen
DE59207013D1 (de)	1996-10-02	Sportschuh
DE69126968D1 (de)	1997-09-04	Tamburin
ATA39792A (de)	1994-11-15	Maehwerk
ATE163916T1 (de)	1998-03-15	Ethyl-6-formyloxy-4-hexenoat
DE69220547D1 (de)	1997-07-31	5-substituierte-2-Oxazolidinone
ATA67791A (de)	1992-05-15	Rollski
BR9201945A (pt)	1993-01-12	Filatorio
CA68725S (fr)	1991-06-18	Mobilier-jeu
BR7101342U (pt)	1993-02-09	Hamburgueira
BR9105653A (pt)	1993-06-29	Ludoquimico
BR9100957A (pt)	1992-10-27	Centrografo
BR9101513A (pt)	1991-09-10	Esfero-movel
BR9101584A (pt)	1992-11-24	Sofa-beliche
BR9102019A (pt)	1992-12-01	Brazbloc

Legal Events

Date	Code	Title	Description
1995-07-02	FD	Application lapsed