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FI914405L - Isoprenoidfosfolipas-a2-inhibitorer och dessa innehaollande preparat. - Google Patents

Isoprenoidfosfolipas-a2-inhibitorer och dessa innehaollande preparat. Download PDF

Info

Publication number
FI914405L
FI914405L FI914405A FI914405A FI914405L FI 914405 L FI914405 L FI 914405L FI 914405 A FI914405 A FI 914405A FI 914405 A FI914405 A FI 914405A FI 914405 L FI914405 L FI 914405L
Authority
FI
Finland
Prior art keywords
isoprenoidfosfolipas
inhibitorer
preparat
dessa innehaollande
och dessa
Prior art date
Application number
FI914405A
Other languages
English (en)
Other versions
FI104168B1 (fi
FI104168B (fi
FI914405A0 (fi
Inventor
F Ivy Carroll
Anita Lewin
Kenneth Tramposch
Stephen A Steiner
Original Assignee
Bristol Myers Squipp Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squipp Company filed Critical Bristol Myers Squipp Company
Publication of FI914405A0 publication Critical patent/FI914405A0/fi
Publication of FI914405L publication Critical patent/FI914405L/fi
Application granted granted Critical
Publication of FI104168B1 publication Critical patent/FI104168B1/fi
Publication of FI104168B publication Critical patent/FI104168B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/64Monocyclic acids with unsaturation outside the aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI914405A 1990-09-21 1991-09-19 Menetelmä terapeuttisesti käyttökelpoisten retinoidiyhdisteiden valmistamiseksi FI104168B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/586,159 US5141959A (en) 1990-09-21 1990-09-21 Isoprenoid phospholipase a2 inhibitors and preparations comprising same
US58615990 1990-09-21

Publications (4)

Publication Number Publication Date
FI914405A0 FI914405A0 (fi) 1991-09-19
FI914405L true FI914405L (fi) 1992-03-22
FI104168B1 FI104168B1 (fi) 1999-11-30
FI104168B FI104168B (fi) 1999-11-30

Family

ID=24344545

Family Applications (1)

Application Number Title Priority Date Filing Date
FI914405A FI104168B (fi) 1990-09-21 1991-09-19 Menetelmä terapeuttisesti käyttökelpoisten retinoidiyhdisteiden valmistamiseksi

Country Status (18)

Country Link
US (1) US5141959A (fi)
EP (1) EP0476682B1 (fi)
JP (1) JP2943089B2 (fi)
AT (1) ATE117979T1 (fi)
AU (1) AU637756B2 (fi)
CA (1) CA2051766A1 (fi)
DE (1) DE69107153T2 (fi)
DK (1) DK0476682T3 (fi)
ES (1) ES2067822T3 (fi)
FI (1) FI104168B (fi)
GR (1) GR3014944T3 (fi)
IE (1) IE66745B1 (fi)
IL (1) IL99536A (fi)
MX (1) MX9101163A (fi)
NZ (1) NZ239844A (fi)
OA (1) OA09514A (fi)
PT (1) PT99014B (fi)
ZA (1) ZA917531B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189737B2 (en) * 1991-08-09 2007-03-13 Research Triangle Institute Cocaine receptor binding ligands
US5688781A (en) 1994-08-19 1997-11-18 Bristol-Myers Squibb Company Method for treating vascular leak syndrome
FR2735371B1 (fr) * 1995-06-19 1997-07-18 Cird Galderma Procede pour identifier des composes antagonistes des recepteurs rars
US6900228B1 (en) * 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
US6267945B1 (en) 1998-12-18 2001-07-31 Neuromed Technologies, Inc. Farnesol-related calcium channel blockers
US6538010B1 (en) * 2000-11-08 2003-03-25 Research Triangle Institute Compounds and methods for promoting smoking cessation
US6495719B2 (en) 2001-03-27 2002-12-17 Circagen Pharmaceutical Histone deacetylase inhibitors
US8026280B2 (en) 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7312247B2 (en) 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
EP1511477A4 (en) * 2002-05-22 2008-04-09 Errant Gene Therapeutics Llc HISTONE DEACETYLASE INHIBITORS BASED ON ALPHA-KETO-EPOXYDE COMPOUNDS
WO2003101177A2 (en) * 2002-06-04 2003-12-11 Sequenom, Inc. Diagnosing predisposition to fat deposition and therapeutic methods for reducing fat deposition and treatment of associated conditions
US20050014158A1 (en) * 2002-06-27 2005-01-20 Adam Gail Isabel Reid Therapeutic methods for reducing fat deposition and treating associated conditions
WO2004002295A2 (en) * 2002-06-27 2004-01-08 Sequenom, Inc. Diagnosing predisposition to fat deposition and associated condition
CA2506504A1 (en) * 2002-11-20 2004-06-03 Errant Gene Therapeutics, Llc Treatment of lung cells with histone deacetylase inhibitors
CA2587013A1 (en) * 2004-11-08 2006-05-18 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7872023B2 (en) * 2005-02-17 2011-01-18 Research Triangle Institute Kappa opioid receptor ligands
US7399762B2 (en) * 2005-04-25 2008-07-15 Research Triangle Institute Opioid receptor agonist compounds and their use in treatment of pain
US7476679B2 (en) * 2005-07-26 2009-01-13 Research Triangle Institute Octahydroisoquinoline compounds as opioid receptor modulators
EP2076124A4 (en) * 2007-04-20 2011-08-03 Acucela Inc STYRENYL DERIVATIVE COMPOUNDS FOR THE TREATMENT OF OPHTHALMOLOGICAL DISEASES AND SUFFERING
US8048895B2 (en) * 2008-04-18 2011-11-01 Research Triangle Institute Kappa opioid receptor ligands
WO2011106039A1 (en) 2010-02-24 2011-09-01 Research Triangle Institute Arylpiperazone opioid receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4194007A (en) * 1978-01-13 1980-03-18 Scott Eugene J Van α-Hydroxyretinoic acid, α-ketoretinoic acid and mixtures and their use in treating skin conditions
US4456618A (en) * 1982-10-15 1984-06-26 Sri International Naphthenic and heterocyclic retinoic acid analogues
US4568757A (en) * 1984-01-30 1986-02-04 Research Triangle Institute Configurationally locked retinoids

Also Published As

Publication number Publication date
GR3014944T3 (en) 1995-05-31
IL99536A (en) 1995-10-31
AU637756B2 (en) 1993-06-03
DE69107153D1 (de) 1995-03-16
EP0476682A1 (en) 1992-03-25
PT99014A (pt) 1992-08-31
PT99014B (pt) 1999-02-26
IE66745B1 (en) 1996-02-07
ZA917531B (en) 1992-07-29
IL99536A0 (en) 1992-08-18
JP2943089B2 (ja) 1999-08-30
FI104168B1 (fi) 1999-11-30
IE913318A1 (en) 1992-02-25
FI104168B (fi) 1999-11-30
JPH04270261A (ja) 1992-09-25
FI914405A0 (fi) 1991-09-19
ATE117979T1 (de) 1995-02-15
MX9101163A (es) 1992-05-04
OA09514A (en) 1992-11-15
CA2051766A1 (en) 1992-03-22
AU8462691A (en) 1992-03-26
ES2067822T3 (es) 1995-04-01
US5141959A (en) 1992-08-25
NZ239844A (en) 1993-04-28
DE69107153T2 (de) 1995-05-24
EP0476682B1 (en) 1995-02-01
DK0476682T3 (da) 1995-04-03

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