FI914228A0 - Azacykliska foereningar. - Google Patents

Azacykliska foereningar.

Info

Publication number: FI914228A0
Authority: FI; Finland
Prior art keywords: azacykliska; foereningar; azacykliska foereningar
Prior art date: 1990-09-10

Application number

FI914228A

Other languages

English (en)

Other versions

FI914228A (fi

Inventor

Franz Ostermayer

Peter Herold

Walter Fuhrer

Original Assignee

Ciba Geigy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-10

Filing date

1991-09-06

Publication date

1991-09-06

1991-09-06 Application filed by Ciba Geigy filed Critical Ciba Geigy

1991-09-06 Publication of FI914228A0 publication Critical patent/FI914228A0/fi

1992-03-11 Publication of FI914228A publication Critical patent/FI914228A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI914228A 1990-09-10 1991-09-06 Azacykliska foereningar. FI914228A (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH292790		1990-09-10

Publications (2)

Publication Number	Publication Date
FI914228A0 true FI914228A0 (fi)	1991-09-06
FI914228A FI914228A (fi)	1992-03-11

Family

ID=4244763

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI914228A FI914228A (fi)	1990-09-10	1991-09-06	Azacykliska foereningar.

Country Status (12)

Country	Link
EP (1)	EP0475898A1 (fi)
JP (1)	JPH04342571A (fi)
KR (1)	KR920006323A (fi)
AU (1)	AU8375591A (fi)
CA (1)	CA2050769A1 (fi)
FI (1)	FI914228A (fi)
HU (1)	HUT59129A (fi)
IE (1)	IE913165A1 (fi)
IL (1)	IL99372A0 (fi)
NO (1)	NO913542L (fi)
PT (1)	PT98903A (fi)
ZA (1)	ZA917143B (fi)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2681067B1 (fr) *	1991-09-10	1993-12-17	Elf Sanofi	Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
IE910913A1 (en) *	1990-03-20	1991-09-25	Sanofi Sa	N-substituted heterocyclic derivates, their preparation¹and pharmaceutical compositions containing them
US5164403A (en) *	1991-04-05	1992-11-17	G. D. Searle & Co.	N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders
WO1992020662A1 (en) *	1991-05-10	1992-11-26	Merck & Co., Inc.	Acidic aralkyl triazole derivatives active as angiotensin ii antagonists
US5436259A (en) *	1991-05-10	1995-07-25	Merck & Co., Inc.	Substituted 1,2,4-triazolin-3-one compounds bearing acidic functional groups as balanced angiotensin II antagonists
CA2115990A1 (en) *	1991-08-19	1993-03-04	George Albert Boswell	Angiotensin ii receptor blocking imidazolinone derivatives
CZ36294A3 (en) *	1991-08-19	1994-07-13	Du Pont	Substituted imidazilonone derivatives and pharmaceutical preparations based thereon
US5182288A (en) *	1991-11-13	1993-01-26	Ortho Pharmaceutical Corporation	Substituted n-biphenylyl lactams
ES2143505T3 (es) *	1992-10-13	2000-05-16	Searle & Co	Compuestos de n-arilheteroarilalquil-1-fenil-imidazol-2-ona para el tratamiento de trastornos circulatorios.
US5411641A (en) *	1993-11-22	1995-05-02	E. I. Du Pont De Nemours And Company	Electrochemical conversion of anhydrous hydrogen halide to halogen gas using a cation-transporting membrane
FR2725987B1 (fr) *	1994-10-19	1997-01-10	Sanofi Sa	Procede pour la preparation d'un derive de tetrazole sous deux formes cristallines et nouvelle forme cristalline de ce derive
TW442301B (en) *	1995-06-07	2001-06-23	Sanofi Synthelabo	Pharmaceutical compositions containing irbesartan
US5994348A (en)	1995-06-07	1999-11-30	Sanofi	Pharmaceutical compositions containing irbesartan
US5728834A (en) *	1996-11-14	1998-03-17	Wyckoff Chemical Company, Inc.	Process for preparation of 4-aryl-1,2,4-triazol-3-ones
FR2766821A1 (fr) *	1997-07-29	1999-02-05	Sanofi Sa	Derives de 1,3-oxazolinyl-biphenyle, leur procede de preparation et leur utilisation comme intermediaires de synthese
GB9716446D0 (en) *	1997-08-05	1997-10-08	Agrevo Uk Ltd	Fungicides
US6162922A (en) *	1998-01-30	2000-12-19	Bristol-Myers Squibb Co.	Method for preparing N-substituted heterocyclic derivatives using a phase-transfer catalyst
US6489487B1 (en)	1998-08-03	2002-12-03	Sumitomo Chemical Company, Limited	Triazolone derivatives, use thereof, and intermediates therefor
SE9903028D0 (sv)	1999-08-27	1999-08-27	Astra Ab	New use
AR038377A1 (es) *	2002-02-08	2005-01-12	Merck & Co Inc	Derivados de n-bifenil-aminocicloalcancarboxamida (con sustitucion con metilo)
ATE316954T1 (de) *	2002-02-08	2006-02-15	Merck & Co Inc	N-biphenylmethylaminocycloalkancarboxamid- derivative
WO2004019868A2 (en)	2002-08-29	2004-03-11	Merck & Co., Inc.	N-biarylmethyl aminocycloalkanecarboxamide derivatives
AU2003242984A1 (en) *	2003-04-07	2004-11-01	Hetero Drugs Limited	A novel crystalline form of irbesartan
CA2534188A1 (en)	2003-08-07	2005-02-24	Merck & Co., Inc.	Sulfonyl substituted n-(biarylmethyl) aminocyclopropanecarboxamides
WO2005113518A1 (en) *	2004-05-20	2005-12-01	Dr. Reddy's Laboratories Ltd.	Process for preparing irbesartan
EP1749828A1 (en)	2005-08-04	2007-02-07	Farmaprojects S.L.	Process for preparing an angiotensin II receptor antagonist
WO2007052301A2 (en) *	2005-08-31	2007-05-10	Alembic Limited	Process for the preparation of irbesartan
CA2604404A1 (en)	2005-10-28	2007-05-03	Alembic Limited	An improved process for preparation of irbesartan
US8106216B2 (en) *	2006-04-24	2012-01-31	Aurobindo Pharma Ltd.	Process for the preparation of Irbesartan
US20100120694A1 (en)	2008-06-04	2010-05-13	Synergy Pharmaceuticals, Inc.	Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
US7879802B2 (en)	2007-06-04	2011-02-01	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2624828T3 (es)	2008-07-16	2017-07-17	Synergy Pharmaceuticals Inc.	Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
EP2194050A1 (en)	2008-12-08	2010-06-09	KRKA, tovarna zdravil, d.d., Novo mesto	A new process for the preparation of irbesartan
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CA2905438A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
AU2014235209B2 (en)	2013-03-15	2018-06-14	Bausch Health Ireland Limited	Guanylate cyclase receptor agonists combined with other drugs
EP3004138B1 (en)	2013-06-05	2024-03-13	Bausch Health Ireland Limited	Ultra-pure agonists of guanylate cyclase c, method of making and using same
CN108276389B (zh) *	2018-02-09	2020-10-16	北京化工大学	一种厄贝沙坦的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5015651A (en) *	1988-01-07	1991-05-14	E. I. Du Pont De Nemours And Company	Treatment of hypertension with 1,2,4-angiotensin II antagonists
EP0409332A3 (en) *	1989-07-19	1991-08-07	Merck & Co. Inc.	Substituted triazoles as angiotensin ii antagonists
DE69024556T2 (de) *	1989-07-28	1996-10-17	Merck & Co Inc	Substituierte Triazolinone, Triazolinthione und Triazolinimine als Angiotensin II-Antagonisten

1991
- 1991-09-02 IL IL99372A patent/IL99372A0/xx unknown
- 1991-09-03 EP EP91810697A patent/EP0475898A1/de not_active Withdrawn
- 1991-09-06 CA CA002050769A patent/CA2050769A1/en not_active Abandoned
- 1991-09-06 FI FI914228A patent/FI914228A/fi unknown
- 1991-09-09 AU AU83755/91A patent/AU8375591A/en not_active Abandoned
- 1991-09-09 NO NO91913542A patent/NO913542L/no unknown
- 1991-09-09 ZA ZA917143A patent/ZA917143B/xx unknown
- 1991-09-09 IE IE316591A patent/IE913165A1/en unknown
- 1991-09-09 HU HU912903A patent/HUT59129A/hu unknown
- 1991-09-09 PT PT98903A patent/PT98903A/pt not_active Application Discontinuation
- 1991-09-10 JP JP3230528A patent/JPH04342571A/ja active Pending
- 1991-09-10 KR KR1019910015739A patent/KR920006323A/ko not_active Application Discontinuation

Also Published As

Publication number	Publication date
JPH04342571A (ja)	1992-11-30
PT98903A (pt)	1992-07-31
EP0475898A1 (de)	1992-03-18
ZA917143B (en)	1992-04-29
CA2050769A1 (en)	1992-03-11
HUT59129A (en)	1992-04-28
FI914228A (fi)	1992-03-11
NO913542L (no)	1992-03-11
AU8375591A (en)	1992-03-12
HU912903D0 (en)	1992-01-28
IE913165A1 (en)	1992-03-11
NO913542D0 (no)	1991-09-09
IL99372A0 (en)	1992-08-18
KR920006323A (ko)	1992-04-27

Publication	Publication Date	Title
FI914228A (fi)	1992-03-11	Azacykliska foereningar.
FI902264A (fi)	1991-11-05	Stoedanordning foer helix-resonator.
FI903633A0 (fi)	1990-07-18	Lysaemnesskikt foer elektroluminescensdisplay.
FI903284A0 (fi)	1990-06-28	Vertikalborrstaong.
FI901742A (fi)	1991-10-07	Anordning foer ryggvaord.
NO905139D0 (no)	1990-11-28	Loesgodscontainer.
FI901531A0 (fi)	1990-03-27	Vaermeaotervinningssystem.
FI903910A (fi)	1992-02-08	Stoppningssystem foer landfordon.
FI903317A0 (fi)	1990-06-29	Foervarningskorg.
FI900377A0 (fi)	1990-01-24	Trallkonstruktion.
FI903376A0 (fi)	1990-07-04	Massageapparat.
ES1014023Y (es)	1991-07-16	Traca pirotecnica.
FI900367A0 (fi)	1990-01-24	Baerbar hydraulisk hammare.
FI901642A0 (fi)	1990-04-02	Bockningsverktyg foer kopparroer.
FI902456A0 (fi)	1990-05-18	Enaxlad arbetsmaskin.
FI902503A0 (fi)	1990-05-21	Jordkomprimeringsanordning.
FI900311A0 (fi)	1990-01-19	Foerglasningsfoerfarande.
FI903082A (fi)	1991-12-20	Fjaederupphaengningssystem foer fordon.
FI900329A0 (fi)	1990-01-22	Skyddsraeck.
FI900308A0 (fi)	1990-01-19	Spaormaskin.
FI903120A0 (fi)	1990-06-20	Rullstol.
FI901500A (fi)	1991-09-27	Stoed foer taong.
FI901405A0 (fi)	1990-03-21	Vaederskydd.
FI903133A0 (fi)	1990-06-20	Tandtransplantation.
FI901345A0 (fi)	1990-03-19	Braedfodringskonstruktion.