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FI913833L - Ringsubstituerade 2-amino -1,2,3,4-tetrahydronaftalener, 3-aminokromaner och 3-aminotiokromaner. - Google Patents

Ringsubstituerade 2-amino -1,2,3,4-tetrahydronaftalener, 3-aminokromaner och 3-aminotiokromaner. Download PDF

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Publication number
FI913833L
FI913833L FI913833A FI913833A FI913833L FI 913833 L FI913833 L FI 913833L FI 913833 A FI913833 A FI 913833A FI 913833 A FI913833 A FI 913833A FI 913833 L FI913833 L FI 913833L
Authority
FI
Finland
Prior art keywords
tetrahydronaphtalener
aminothiochromaner
aminochromaner
substituerade
och
Prior art date
Application number
FI913833A
Other languages
English (en)
Other versions
FI913833A0 (fi
Inventor
Craig Steven Hoechstetter
Diane Lynn Huser
Jr Charles Johnson Paget
John Mehnert Schaus
Robert Daniel Titus
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI913833A0 publication Critical patent/FI913833A0/fi
Publication of FI913833L publication Critical patent/FI913833L/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Lubricants (AREA)
  • Pyrane Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI913833A 1990-08-15 1991-08-13 Ringsubstituerade 2-amino -1,2,3,4-tetrahydronaftalener, 3-aminokromaner och 3-aminotiokromaner. FI913833L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56798590A 1990-08-15 1990-08-15

Publications (2)

Publication Number Publication Date
FI913833A0 FI913833A0 (fi) 1991-08-13
FI913833L true FI913833L (fi) 1992-02-16

Family

ID=24269428

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913833A FI913833L (fi) 1990-08-15 1991-08-13 Ringsubstituerade 2-amino -1,2,3,4-tetrahydronaftalener, 3-aminokromaner och 3-aminotiokromaner.

Country Status (25)

Country Link
US (5) US5286753A (fi)
EP (1) EP0471515B1 (fi)
JP (1) JPH04244050A (fi)
KR (1) KR920004331A (fi)
CN (1) CN1039967C (fi)
AT (1) ATE149480T1 (fi)
AU (1) AU652569B2 (fi)
CA (1) CA2048846A1 (fi)
CZ (1) CZ281137B6 (fi)
DE (1) DE69124868T2 (fi)
DK (1) DK0471515T3 (fi)
ES (1) ES2100211T3 (fi)
FI (1) FI913833L (fi)
GR (1) GR3023409T3 (fi)
HU (1) HU218668B (fi)
IE (1) IE912880A1 (fi)
IL (1) IL99175A (fi)
MX (1) MX9100675A (fi)
MY (1) MY110619A (fi)
NO (1) NO176094C (fi)
NZ (1) NZ239371A (fi)
PT (1) PT98641B (fi)
RU (1) RU2060245C1 (fi)
YU (1) YU48695B (fi)
ZA (1) ZA916425B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0389425B1 (de) * 1989-03-22 1995-04-26 Ciba-Geigy Ag Neue Benzothiopyranylamine
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
US5340838A (en) * 1990-05-04 1994-08-23 Eli Lilly And Company Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines
DK0471515T3 (da) * 1990-08-15 1997-07-21 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
DK0712837T3 (da) * 1991-02-08 2000-11-20 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronaphtalener og 3-aminochromaner
AU654573B2 (en) * 1991-08-21 1994-11-10 Eli Lilly And Company Benzo(f)quinolinones
FR2691149B1 (fr) * 1992-05-18 1994-07-08 Adir Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
WO1994022495A1 (en) * 1993-03-31 1994-10-13 The Trustees Of The University Of Pennsylvania Dopamine d-3 and serotonin (5-ht1a) receptor ligands and imaging agents
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
FR2717175B1 (fr) * 1994-03-11 1996-06-14 Adir Nouveaux composés alkylaminoindanes, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
US5482942A (en) * 1994-06-28 1996-01-09 American Home Products Corporation (3,4-dioxocyclobuten-1-yl)chromene, indene, and dihydronaphthalenone derivatives as smooth muscle relaxants
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
EP1052982A4 (en) * 1997-04-30 2004-10-06 Lilly Co Eli AMINOTETRALINS AS AGONISTS OF 5-HT 1D $ g (a)?
US6355674B1 (en) 1997-04-30 2002-03-12 Eli Lilly And Company Aminotetralins as 5-HT1D α Agonists
US5962488A (en) * 1998-04-08 1999-10-05 Roberts Laboratories, Inc. Stable pharmaceutical formulations for treating internal bowel syndrome containing isoxazole derivatives
FR2792529B1 (fr) * 1999-04-26 2001-09-28 Sod Conseils Rech Applic Nouvelles compositions pharmaceutiques comprenant des derives de 2-isoxazole-8-aminotetralines
US7060847B2 (en) * 2003-07-18 2006-06-13 Roche Diagnostics Operations, Inc. Ecstasy-class derivatives, immunogens, and antibodies and their use in detecting ecstasy-class drugs

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3637740A (en) * 1969-04-21 1972-01-25 Pfizer Aminobenzocycloalkane compounds
US3930022A (en) * 1972-07-03 1975-12-30 Squibb & Sons Inc Certain tetrahydronaphthalenes used in the treatment of cardiac arrhythmia
DE3062971D1 (en) * 1979-09-14 1983-06-09 Sandoz Ag Derivatives of tetraline, their preparation and medicaments containing these compounds
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
JPS5970653A (ja) * 1982-10-15 1984-04-21 Takeda Chem Ind Ltd 眼圧低下剤
US4520030A (en) * 1983-12-12 1985-05-28 Synthelabo Anti-ulcer agents
US4975461A (en) * 1986-06-19 1990-12-04 E. R. Squibb & Sons, Inc. P-aminophenols, derivatives thereof and method of use
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
CA1331191C (en) * 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives
CA1335591C (en) * 1988-05-23 1995-05-16 James Arthur Nixon Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes
US4873265A (en) * 1988-07-14 1989-10-10 Thomes Pharmacal Co., Inc. Anti-infective methods and compositions
IL93464A (en) * 1989-02-27 1996-10-16 Lilly Co Eli 2-Amino-1,2,3,4-Tetrahydronaplanin and 3 aminochromes with a transformed ring, a process for their preparation and pharmaceutical preparations containing them
CA1335106C (en) * 1989-02-27 1995-04-04 John Mehnert Schaus Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
US5306830A (en) * 1989-04-27 1994-04-26 The Upjohn Company Substituted 3-amino chromans
DE69005625T2 (de) * 1989-04-27 1994-05-11 Upjohn Co Substituierte 3-amino-chromane.
BE1004067A6 (fr) * 1989-05-23 1992-09-15 Cockerill Sambre Sa Dispositif d'arret d'urgence pour installation industrielle.
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
EP0476016B1 (en) * 1989-05-31 1998-10-28 PHARMACIA & UPJOHN COMPANY CNS active 8-heterocyclyl-2-aminotetralin derivatives
SE8904361D0 (sv) * 1989-12-22 1989-12-22 Astra Ab New chroman and thiochroman derivatives
US5229410A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
DK0471515T3 (da) * 1990-08-15 1997-07-21 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronphtalener, 3-aminochromaner og 3-aminothiochromaner
DK0712837T3 (da) * 1991-02-08 2000-11-20 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronaphtalener og 3-aminochromaner
FR2689509B1 (fr) * 1992-04-01 1994-06-03 Adir Nouveaux derives spiraniques du 3-amino chromane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
ATE149480T1 (de) 1997-03-15
AU652569B2 (en) 1994-09-01
NO913175D0 (no) 1991-08-14
US5426229A (en) 1995-06-20
US5466709A (en) 1995-11-14
EP0471515A1 (en) 1992-02-19
RU2060245C1 (ru) 1996-05-20
NO913175L (no) 1992-02-17
DK0471515T3 (da) 1997-07-21
AU8240391A (en) 1992-02-20
US5470977A (en) 1995-11-28
IE912880A1 (en) 1992-02-26
NZ239371A (en) 1993-01-27
ES2100211T3 (es) 1997-06-16
CA2048846A1 (en) 1992-02-16
PT98641B (pt) 1999-01-29
NO176094B (no) 1994-10-24
IL99175A (en) 1998-06-15
HUT61965A (en) 1993-03-29
US5286753A (en) 1994-02-15
KR920004331A (ko) 1992-03-27
DE69124868T2 (de) 1997-07-10
IL99175A0 (en) 1992-07-15
PT98641A (pt) 1992-06-30
CN1039967C (zh) 1998-09-30
EP0471515B1 (en) 1997-03-05
CN1059903A (zh) 1992-04-01
NO176094C (no) 1995-02-01
JPH04244050A (ja) 1992-09-01
DE69124868D1 (de) 1997-04-10
MY110619A (en) 1998-09-30
HU218668B (hu) 2000-10-28
ZA916425B (en) 1993-04-28
HU912708D0 (en) 1992-01-28
CZ281137B6 (cs) 1996-06-12
CS249391A3 (en) 1992-03-18
MX9100675A (es) 1992-04-01
US5552444A (en) 1996-09-03
GR3023409T3 (en) 1997-08-29
FI913833A0 (fi) 1991-08-13
YU140291A (sh) 1994-01-20
YU48695B (sh) 1999-07-28

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