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FI912220A0 - Heterocykliska foereningar. - Google Patents

Heterocykliska foereningar.

Info

Publication number
FI912220A0
FI912220A0 FI912220A FI912220A FI912220A0 FI 912220 A0 FI912220 A0 FI 912220A0 FI 912220 A FI912220 A FI 912220A FI 912220 A FI912220 A FI 912220A FI 912220 A0 FI912220 A0 FI 912220A0
Authority
FI
Finland
Prior art keywords
heterocycliska
foereningar
heterocycliska foereningar
Prior art date
Application number
FI912220A
Other languages
English (en)
Other versions
FI912220A (fi
Inventor
David Anthony Roberts
Robert James Pearce
Robert Hugh Bradbury
Andrew Peter Thomas
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of FI912220A0 publication Critical patent/FI912220A0/fi
Publication of FI912220A publication Critical patent/FI912220A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
FI912220A 1990-05-09 1991-05-08 Heterocykliska foereningar. FI912220A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909010394A GB9010394D0 (en) 1990-05-09 1990-05-09 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
FI912220A0 true FI912220A0 (fi) 1991-05-08
FI912220A FI912220A (fi) 1991-11-10

Family

ID=10675695

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912220A FI912220A (fi) 1990-05-09 1991-05-08 Heterocykliska foereningar.

Country Status (10)

Country Link
US (1) US5369114A (fi)
EP (1) EP0456442A1 (fi)
JP (1) JPH04225959A (fi)
AU (1) AU7628591A (fi)
CA (1) CA2042126A1 (fi)
FI (1) FI912220A (fi)
GB (1) GB9010394D0 (fi)
IE (1) IE911561A1 (fi)
NZ (1) NZ238088A (fi)
ZA (1) ZA913512B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE902909A1 (en) * 1989-08-11 1991-02-27 Ici Plc Nitrogen compounds
US6117885A (en) * 1992-02-14 2000-09-12 E. R. Squibb & Sons, Inc. Biphenyl-substituted quinoline derivatives
DE4215587A1 (de) * 1992-05-12 1993-11-18 Bayer Ag Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
US6608048B2 (en) 2000-03-28 2003-08-19 Wyeth Holdings Tricyclic protein kinase inhibitors
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
UY30244A1 (es) 2006-03-30 2007-11-30 Tanabe Seiyaku Co Un proceso para preparar derivados de tetrahidroquinolina
CA2688161C (en) 2007-06-04 2020-10-20 Kunwar Shailubhai Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP2968439A2 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
KR102272746B1 (ko) 2013-06-05 2021-07-08 보슈 헬스 아일랜드 리미티드 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법
TW202409008A (zh) 2022-07-05 2024-03-01 荷蘭商新阿姆斯特丹製藥公司 奧比特拉(obicetrapib)鹽及彼等之製造方法與中間體

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1188364A (en) * 1967-05-02 1970-04-15 May & Baker Ltd Quinoline Derivatives
FR2143526A1 (en) * 1971-06-28 1973-02-09 Aries Robert 3-carboxy-4-salicyloxy-6-sulphamoylquinolines - with analgesic,antiinflammatory, antipyretic, antirheumatic activity
US4034075A (en) * 1972-07-03 1977-07-05 Allen & Hanburys Limited Quinaldic acid derivatives
GB1383088A (en) * 1972-07-03 1975-02-05 Allen & Hanburys Ltd Pharmacologically active quinaldamide derivatives
US4461896A (en) * 1979-02-07 1984-07-24 Norwich Eaton Pharmaceuticals, Inc. 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids
DE3373469D1 (en) * 1982-09-30 1987-10-15 Merck & Co Inc 1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents
US4920133A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920130A (en) * 1987-11-02 1990-04-24 Rorer Pharamceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
US4920131A (en) * 1987-11-03 1990-04-24 Rorer Pharmaceutical Corp. Quinoline derivatives and use thereof as antagonists of leukotriene D4
IL89029A (en) * 1988-01-29 1993-01-31 Lilly Co Eli Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them
IL89028A0 (en) * 1988-01-29 1989-08-15 Lilly Co Eli Quinoline,quinazoline and cinnoline derivatives
IE902909A1 (en) * 1989-08-11 1991-02-27 Ici Plc Nitrogen compounds
GB2234748B (en) * 1989-08-11 1993-06-30 Ici Plc Quinoline derivatives, process for their preparation and their use as medicaments
IE903911A1 (en) * 1989-11-20 1991-05-22 Ici Plc Diazine derivatives
EP0453210A3 (en) * 1990-04-19 1993-01-13 Imperial Chemical Industries Plc Pyridine derivatives
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
US5246944A (en) * 1991-08-13 1993-09-21 Merck & Co., Inc. Quinoline angiotensin ii antagonists incorporating a substituted benzyl element
US5227387A (en) * 1991-09-03 1993-07-13 Dowelanco Quinoline nematicidal method

Also Published As

Publication number Publication date
IE911561A1 (en) 1991-11-20
EP0456442A1 (en) 1991-11-13
JPH04225959A (ja) 1992-08-14
AU7628591A (en) 1991-11-14
CA2042126A1 (en) 1991-11-10
GB9010394D0 (en) 1990-06-27
FI912220A (fi) 1991-11-10
NZ238088A (en) 1993-06-25
US5369114A (en) 1994-11-29
ZA913512B (en) 1992-01-29

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