FI91152B - Menetelmä terapeuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi - Google Patents
Menetelmä terapeuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksiInfo
- Publication number
- FI91152B FI91152B FI873205A FI873205A FI91152B FI 91152 B FI91152 B FI 91152B FI 873205 A FI873205 A FI 873205A FI 873205 A FI873205 A FI 873205A FI 91152 B FI91152 B FI 91152B
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- therapeutically active
- benzimidazole derivatives
- active benzimidazole
- derivatives
- Prior art date
Links
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 125000003785 benzimidazolyl group Chemical class N1=C(NC2=C1C=CC=C2)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17375986 | 1986-07-25 | ||
| JP17375986 | 1986-07-25 | ||
| JP17113987 | 1987-07-10 | ||
| JP62171139A JPH0784462B2 (ja) | 1986-07-25 | 1987-07-10 | ベンゾイミダゾ−ル誘導体 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI873205A0 FI873205A0 (fi) | 1987-07-21 |
| FI873205A FI873205A (fi) | 1988-01-26 |
| FI91152B true FI91152B (fi) | 1994-02-15 |
| FI91152C FI91152C (fi) | 1994-05-25 |
Family
ID=26493951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI873205A FI91152C (fi) | 1986-07-25 | 1987-07-21 | Menetelmä terapeuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4886803A (fi) |
| EP (1) | EP0254322B1 (fi) |
| JP (1) | JPH0784462B2 (fi) |
| KR (1) | KR960011388B1 (fi) |
| AU (1) | AU597696B2 (fi) |
| CA (1) | CA1305481C (fi) |
| DE (1) | DE3781845T2 (fi) |
| ES (1) | ES2044878T3 (fi) |
| FI (1) | FI91152C (fi) |
| NO (1) | NO168770C (fi) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0334809B1 (de) * | 1988-03-21 | 1994-06-15 | Ciba-Geigy Ag | Mittel zum Schutz von Pflanzen gegen Krankheiten |
| US5089592A (en) * | 1988-06-09 | 1992-02-18 | The Dow Chemical Company | Biscyclobutarene monomer comprising two cyclobutarene moieties bridged by a divalent radical comprising at least one benzothiazole or benzimidazole linkage |
| IT1251144B (it) * | 1991-07-30 | 1995-05-04 | Boehringer Ingelheim Italia | Derivati del benzimidazolone |
| DE69311278T2 (de) * | 1992-12-16 | 1997-10-30 | Takeda Chemical Industries Ltd | Stabile pharmazeutische Zubereitung mit Fumagillolderivaten |
| US5637724A (en) * | 1995-06-05 | 1997-06-10 | Neurogen Corporation | Substituted aryl and cycloalkyl imidazolones; a new class of GABA brain receptor ligands |
| US5637725A (en) * | 1995-06-05 | 1997-06-10 | Neurogen Corporation | Substituted aryl and cycloalkyl imidazolones; a new class of GABA brain receptor ligands |
| TW381092B (en) * | 1995-07-07 | 2000-02-01 | Otsuka Pharma Co Ltd | Novel benzimidazole derivatives for use in treating arteriosclerotic diseases |
| IL150526A0 (en) * | 2000-02-09 | 2003-02-12 | Procter & Gamble | 2-phenylcarbamoyl-benzimidazoles |
| US7183410B2 (en) * | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
| US20030060475A1 (en) * | 2001-08-10 | 2003-03-27 | Boehringer Ingelheim Pharma Kg | Method of using flibanserin for neuroprotection |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| UA78974C2 (en) * | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| FR2833494B1 (fr) * | 2001-12-19 | 2006-12-15 | Univ Nantes | Utilisation de composes de la famille des benzamides comme agent immunosuppresseur |
| JP2005289816A (ja) * | 2002-05-14 | 2005-10-20 | Banyu Pharmaceut Co Ltd | ベンズイミダゾール誘導体 |
| CA2503844A1 (en) * | 2002-10-30 | 2004-05-21 | Merck & Co., Inc. | Piperidinyl-alpha-aminoamide modulators of chemokine receptor activity |
| US7741341B2 (en) | 2003-05-19 | 2010-06-22 | Sanofi-Aventis Deutschland Gmbh | Benzimidazole-derivatives as factor Xa inhibitors |
| EP1479676A1 (en) * | 2003-05-19 | 2004-11-24 | Aventis Pharma Deutschland GmbH | Benzimidazole-derivatives as factor xa inhibitors |
| WO2005102342A1 (en) * | 2004-04-22 | 2005-11-03 | Boehringer Ingelheim International Gmbh | New pharmaceutical compositions for the treatment of sexual disorders ii |
| US20050239798A1 (en) * | 2004-04-22 | 2005-10-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Method for the treatment of premenstrual and other female sexual disorders |
| WO2006076009A2 (en) | 2004-04-23 | 2006-07-20 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| US20060025420A1 (en) * | 2004-07-30 | 2006-02-02 | Boehringer Ingelheimn International GmbH | Pharmaceutical compositions for the treatment of female sexual disorders |
| CA2576812A1 (en) * | 2004-09-03 | 2006-03-09 | Boehringer Ingelheim International Gmbh | Method for the treatment of attention deficit hyperactivity disorder |
| WO2006096439A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of schizophrenia and related diseases |
| WO2006096434A2 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders |
| CA2599721A1 (en) * | 2005-03-04 | 2006-09-14 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for the treatment and/or prevention of depression |
| CA2608249A1 (en) * | 2005-05-06 | 2006-11-16 | Boehringer Ingelheim International Gmbh | Method for the treatment of drug abuse with flibanserin |
| CA2608363A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of drug-induced sexual dysfunction |
| CA2608713A1 (en) * | 2005-05-19 | 2006-11-23 | Boehringer Ingelheim International Gmbh | Method for the treatment of sexual dysfunctions due to medical conditions |
| PL1912650T3 (pl) | 2005-08-03 | 2018-01-31 | Sprout Pharmaceuticals Inc | Zastosowanie flibanseryny w leczeniu otyłości |
| EP1939175B1 (en) | 2005-09-27 | 2017-03-01 | Shionogi&Co., Ltd. | Sulfonamide derivative having pgd2 receptor antagonistic activity |
| US20070123540A1 (en) * | 2005-10-29 | 2007-05-31 | Angelo Ceci | Sexual desire enhancing medicaments comprising benzimidazolone derivatives |
| CA2626134C (en) * | 2005-10-29 | 2013-12-24 | Boehringer Ingelheim International Gmbh | Benzimidazolone derivatives for the treatment of premenstrual and other female sexual disorders |
| US20070105869A1 (en) * | 2005-11-08 | 2007-05-10 | Stephane Pollentier | Use of flibanserin for the treatment of pre-menopausal sexual desire disorders |
| EP2021006B1 (en) * | 2006-05-09 | 2015-08-12 | Sprout Pharmaceuticals, Inc. | Use of flibanserin for the treatment of post-menopausal sexual desire disorders |
| ATE456369T1 (de) | 2006-06-30 | 2010-02-15 | Boehringer Ingelheim Int | Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen |
| US20090318469A1 (en) * | 2006-07-14 | 2009-12-24 | Boehringer Ingelheim International Gmbh | Use of Flibanserin for the Treatment of Sexual Disorders in Females |
| EA200900264A1 (ru) * | 2006-08-14 | 2009-08-28 | Бёрингер Ингельхайм Интернациональ Гмбх | Композиции флибансерина и способ их приготовления |
| CL2007002214A1 (es) * | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| AR062321A1 (es) * | 2006-08-25 | 2008-10-29 | Boehringer Ingelheim Int | Sistema de liberacion controlada y metodo para fabricarlo |
| ES2627221T3 (es) | 2006-12-28 | 2017-07-27 | Rigel Pharmaceuticals, Inc. | Compuestos de heterocicloalquiloxibenzamida N-sustituidos y métodos de uso |
| PE20091188A1 (es) * | 2007-09-12 | 2009-08-31 | Boehringer Ingelheim Int | Compuesto 1-[2-(4-(3-trifluorometil-fenil)piperazin-1-il)etil]-2,3-dihidro-1h-benzimidazol-2-ona (flibanserina), sus sales de adicion y composiciones farmaceuticas que los contienen |
| CA2771568A1 (en) * | 2009-09-04 | 2011-03-10 | Novartis Ag | Heteroaryl compounds as kinase inhibitors |
| SG183192A1 (en) | 2010-03-10 | 2012-09-27 | Ingenium Pharmaceuticals Gmbh | Inhibitors of protein kinases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4634704A (en) * | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
-
1987
- 1987-07-10 JP JP62171139A patent/JPH0784462B2/ja not_active Expired - Fee Related
- 1987-07-15 US US07/073,738 patent/US4886803A/en not_active Expired - Lifetime
- 1987-07-16 CA CA000542315A patent/CA1305481C/en not_active Expired - Fee Related
- 1987-07-21 FI FI873205A patent/FI91152C/fi not_active IP Right Cessation
- 1987-07-21 AU AU75965/87A patent/AU597696B2/en not_active Ceased
- 1987-07-23 NO NO873091A patent/NO168770C/no unknown
- 1987-07-24 ES ES87110741T patent/ES2044878T3/es not_active Expired - Lifetime
- 1987-07-24 DE DE8787110741T patent/DE3781845T2/de not_active Expired - Fee Related
- 1987-07-24 EP EP87110741A patent/EP0254322B1/en not_active Expired - Lifetime
- 1987-07-25 KR KR1019870008108A patent/KR960011388B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US4886803A (en) | 1989-12-12 |
| DE3781845T2 (de) | 1993-02-18 |
| ES2044878T3 (es) | 1994-01-16 |
| KR880001611A (ko) | 1988-04-25 |
| AU597696B2 (en) | 1990-06-07 |
| NO168770C (no) | 1992-04-01 |
| NO873091D0 (no) | 1987-07-23 |
| KR960011388B1 (ko) | 1996-08-22 |
| JPS63146871A (ja) | 1988-06-18 |
| JPH0784462B2 (ja) | 1995-09-13 |
| AU7596587A (en) | 1988-01-28 |
| FI873205A0 (fi) | 1987-07-21 |
| NO873091L (no) | 1988-01-26 |
| EP0254322B1 (en) | 1992-09-23 |
| FI873205A (fi) | 1988-01-26 |
| EP0254322A1 (en) | 1988-01-27 |
| DE3781845D1 (de) | 1992-10-29 |
| FI91152C (fi) | 1994-05-25 |
| CA1305481C (en) | 1992-07-21 |
| NO168770B (no) | 1991-12-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| MM | Patent lapsed |
Owner name: NISSHIN FLOUR MILLING CO., LTD |