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FI910448A - Menetelmä terapeuttisesti käyttökelpoisten 1,2,3,3a,8,8a-heksahydro-1,3a,8-trimetyylipyrrolo/2,3b/indolijohdannaisten valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten 1,2,3,3a,8,8a-heksahydro-1,3a,8-trimetyylipyrrolo/2,3b/indolijohdannaisten valmistamiseksi Download PDF

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Publication number
FI910448A
FI910448A FI910448A FI910448A FI910448A FI 910448 A FI910448 A FI 910448A FI 910448 A FI910448 A FI 910448A FI 910448 A FI910448 A FI 910448A FI 910448 A FI910448 A FI 910448A
Authority
FI
Finland
Prior art keywords
trimethylpyrrolo
hexahydro
preparation
therapeutically useful
indole derivatives
Prior art date
Application number
FI910448A
Other languages
English (en)
Swedish (sv)
Other versions
FI910448A0 (fi
FI94759B (fi
FI94759C (fi
Inventor
Gerald Joseph O'malley
Richard Charles Allen
John Irving White
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI910448A0 publication Critical patent/FI910448A0/fi
Publication of FI910448A publication Critical patent/FI910448A/fi
Publication of FI94759B publication Critical patent/FI94759B/fi
Application granted granted Critical
Publication of FI94759C publication Critical patent/FI94759C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI910448A 1990-02-01 1991-01-30 Menetelmä terapeuttisesti käyttökelpoisten 1,2,3,3a,8,8a-heksahydro-1,3a,8-trimetyylipyrrolo/2,3b/indolijohdannaisten valmistamiseksi FI94759C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48070690 1990-02-01
US07/480,706 US4983616A (en) 1990-02-01 1990-02-01 Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds

Publications (4)

Publication Number Publication Date
FI910448A0 FI910448A0 (fi) 1991-01-30
FI910448A true FI910448A (fi) 1991-08-02
FI94759B FI94759B (fi) 1995-07-14
FI94759C FI94759C (fi) 1995-10-25

Family

ID=23909022

Family Applications (1)

Application Number Title Priority Date Filing Date
FI910448A FI94759C (fi) 1990-02-01 1991-01-30 Menetelmä terapeuttisesti käyttökelpoisten 1,2,3,3a,8,8a-heksahydro-1,3a,8-trimetyylipyrrolo/2,3b/indolijohdannaisten valmistamiseksi

Country Status (17)

Country Link
US (1) US4983616A (fi)
EP (1) EP0440145A1 (fi)
JP (1) JP3042902B2 (fi)
KR (1) KR0182296B1 (fi)
AU (1) AU629094B2 (fi)
CA (1) CA2035397C (fi)
CZ (1) CZ281612B6 (fi)
FI (1) FI94759C (fi)
HU (1) HU217119B (fi)
IE (1) IE910333A1 (fi)
IL (1) IL97113A (fi)
NO (1) NO175899C (fi)
NZ (1) NZ236944A (fi)
PL (1) PL288904A1 (fi)
PT (1) PT96627A (fi)
TW (1) TW206228B (fi)
ZA (1) ZA91725B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US5187165A (en) * 1987-05-15 1993-02-16 Hoechst-Roussel Pharmaceuticals Inc. Memory enhancing and analgesic 1,2,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di(and tri)methylpyrrolo[2,3-b]indoles
AU634654B2 (en) * 1990-05-11 1993-02-25 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments
US5665880A (en) * 1996-10-31 1997-09-09 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseretholes
US5677457A (en) * 1996-12-19 1997-10-14 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseroline ethers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2934657A1 (de) * 1979-08-28 1981-03-12 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von thiochlorformiaten.
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4680172A (en) * 1985-03-05 1987-07-14 Ciba-Geigy Corporation Devices and methods for treating memory impairment
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
IT1225462B (it) * 1987-04-03 1990-11-14 Mediolanum Farmaceutici Srl Sali organici di derivati della fisostigmina
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
AU634654B2 (en) * 1990-05-11 1993-02-25 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments
AU634380B2 (en) * 1990-05-17 1993-02-18 Hoechst-Roussel Pharmaceuticals Incorporated Alpha-oxopyrrolo(2,3-b)indole acetic acids, esters, amides and related analogs, a process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
NZ236944A (en) 1993-02-25
IL97113A (en) 1994-10-21
IE910333A1 (en) 1991-08-14
HU217119B (hu) 1999-11-29
ZA91725B (en) 1991-11-27
KR910021401A (ko) 1991-12-20
FI910448A0 (fi) 1991-01-30
NO910372L (no) 1991-08-02
IL97113A0 (en) 1992-03-29
AU7011191A (en) 1991-08-08
PT96627A (pt) 1991-10-15
FI94759B (fi) 1995-07-14
EP0440145A1 (en) 1991-08-07
NO910372D0 (no) 1991-01-31
NO175899C (no) 1994-12-28
NO175899B (no) 1994-09-19
KR0182296B1 (ko) 1999-05-01
CA2035397A1 (en) 1991-08-02
HUT60499A (en) 1992-09-28
FI94759C (fi) 1995-10-25
CZ281612B6 (cs) 1996-11-13
AU629094B2 (en) 1992-09-24
US4983616A (en) 1991-01-08
HU910325D0 (en) 1991-08-28
TW206228B (fi) 1993-05-21
PL288904A1 (en) 1992-08-10
CA2035397C (en) 2001-10-23
CS9100215A2 (en) 1991-09-15
JPH04330076A (ja) 1992-11-18
JP3042902B2 (ja) 2000-05-22

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Owner name: HOECHST MARION ROUSSEL, INC.