FI900729A0 - Menetelmä uusien terapeuttisesti aktiivisten 7-metoksimetyylioksi-2,3,4,5-tetrahydro-1H-3-bentsatsepiinien valmistamiseksi - Google Patents
Menetelmä uusien terapeuttisesti aktiivisten 7-metoksimetyylioksi-2,3,4,5-tetrahydro-1H-3-bentsatsepiinien valmistamiseksiInfo
- Publication number
- FI900729A0 FI900729A0 FI900729A FI900729A FI900729A0 FI 900729 A0 FI900729 A0 FI 900729A0 FI 900729 A FI900729 A FI 900729A FI 900729 A FI900729 A FI 900729A FI 900729 A0 FI900729 A0 FI 900729A0
- Authority
- FI
- Finland
- Prior art keywords
- benzazepines
- tetrahydro
- methoxymethyloxy
- preparation
- therapeutically active
- Prior art date
Links
- VMVOUHZAYIQIHS-UHFFFAOYSA-N 7-(methoxymethoxy)-2,3,4,5-tetrahydro-1h-3-benzazepine Chemical class C1CNCCC2=CC(OCOC)=CC=C21 VMVOUHZAYIQIHS-UHFFFAOYSA-N 0.000 title 1
- MWVMYAWMFTVYED-UHFFFAOYSA-N 2,3,4,5-tetrahydro-1h-3-benzazepine Chemical class C1CNCCC2=CC=CC=C21 MWVMYAWMFTVYED-UHFFFAOYSA-N 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- -1 methoxymethyloxy group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK067489A DK67489D0 (da) | 1989-02-14 | 1989-02-14 | Nye benzazepinderivater |
| DK67489 | 1989-02-14 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI900729A0 true FI900729A0 (fi) | 1990-02-14 |
| FI94956B FI94956B (fi) | 1995-08-15 |
| FI94956C FI94956C (fi) | 1995-11-27 |
Family
ID=8096246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI900729A FI94956C (fi) | 1989-02-14 | 1990-02-14 | Menetelmä uusien terapeuttisesti aktiivisten 7-metoksimetyylioksi-2,3,4,5-tetrahydro-1H-3-bentsatsepiinien valmistamiseksi |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5079243A (fi) |
| EP (1) | EP0383247B1 (fi) |
| JP (1) | JPH03197463A (fi) |
| AT (1) | ATE109473T1 (fi) |
| AU (1) | AU624678B2 (fi) |
| DE (1) | DE69011150T2 (fi) |
| DK (2) | DK67489D0 (fi) |
| ES (1) | ES2058626T3 (fi) |
| FI (1) | FI94956C (fi) |
| IE (1) | IE64967B1 (fi) |
| IL (1) | IL93287A0 (fi) |
| NO (1) | NO174746C (fi) |
| NZ (1) | NZ232491A (fi) |
| PT (1) | PT93133B (fi) |
| ZA (1) | ZA901079B (fi) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5470850A (en) * | 1992-02-24 | 1995-11-28 | Novo Nordisk A/S | 2,3,4,5-tetrahydro-1H-3-benzazepines |
| DK23392D0 (da) * | 1992-02-24 | 1992-02-24 | Novo Nordisk As | Heterocykliske forbindelser, deres anvendelse og fremstilling |
| JP5258561B2 (ja) * | 2005-07-15 | 2013-08-07 | アルバニー モレキュラー リサーチ， インコーポレイテッド | アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3393192A (en) * | 1965-04-26 | 1968-07-16 | Schering Corp | Novel benzazepines |
| CA974989A (en) * | 1968-03-11 | 1975-09-23 | Wallace And Tiernan Inc. | Process for preparing 1,2,4,5-tetrahydro-3h,3-benzazepines and products obtained thereby |
| US4111957A (en) * | 1977-02-02 | 1978-09-05 | Smithkline Corporation | Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds |
| US4187314A (en) * | 1977-02-02 | 1980-02-05 | Smithkline Corporation | Substituted furyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds and pharmaceutical use |
| ZA792043B (en) * | 1978-05-08 | 1980-05-28 | Scherico Ltd | Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof and pharmaceutical compositions containing them |
| US4349472A (en) * | 1979-04-27 | 1982-09-14 | Schering Corporation | (S)-8(1-Adamantanecarbonyloxy)-7-chloro-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
| CA1234110A (en) * | 1983-08-12 | 1988-03-15 | Joel G. Berger | Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions |
| DK180485D0 (da) * | 1985-04-22 | 1985-04-23 | Novo Industri As | Nitrogenholdige forbindelser |
| PH27337A (en) * | 1987-03-27 | 1993-06-08 | Schering Corp | Substituted benzazepines their preparation and pharmaceutical compositions containing them |
| DK107688D0 (da) * | 1988-03-01 | 1988-03-01 | Novo Industri As | Carbaminsyreestere af substituerede 7-hydroxy-2,3,4,5-tetrahydro-1h-3-benzazepiner |
| DK325188D0 (da) * | 1988-06-15 | 1988-06-15 | Novo Industri As | Hidtil ukendte benzazepinderivater |
-
1989
- 1989-02-14 DK DK067489A patent/DK67489D0/da not_active Application Discontinuation
-
1990
- 1990-02-05 IE IE40090A patent/IE64967B1/en not_active IP Right Cessation
- 1990-02-06 IL IL93287A patent/IL93287A0/xx not_active IP Right Cessation
- 1990-02-08 US US07/477,284 patent/US5079243A/en not_active Expired - Fee Related
- 1990-02-12 DK DK90102747.4T patent/DK0383247T3/da active
- 1990-02-12 NZ NZ232491A patent/NZ232491A/en unknown
- 1990-02-12 DE DE69011150T patent/DE69011150T2/de not_active Expired - Fee Related
- 1990-02-12 EP EP90102747A patent/EP0383247B1/en not_active Expired - Lifetime
- 1990-02-12 ES ES90102747T patent/ES2058626T3/es not_active Expired - Lifetime
- 1990-02-12 AT AT90102747T patent/ATE109473T1/de active
- 1990-02-13 NO NO900700A patent/NO174746C/no unknown
- 1990-02-13 JP JP2029753A patent/JPH03197463A/ja active Pending
- 1990-02-13 PT PT93133A patent/PT93133B/pt not_active IP Right Cessation
- 1990-02-13 AU AU49352/90A patent/AU624678B2/en not_active Ceased
- 1990-02-13 ZA ZA901079A patent/ZA901079B/xx unknown
- 1990-02-14 FI FI900729A patent/FI94956C/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE109473T1 (de) | 1994-08-15 |
| PT93133A (pt) | 1990-08-31 |
| JPH03197463A (ja) | 1991-08-28 |
| AU624678B2 (en) | 1992-06-18 |
| EP0383247A1 (en) | 1990-08-22 |
| NO174746C (no) | 1994-06-29 |
| IE64967B1 (en) | 1995-09-20 |
| FI94956B (fi) | 1995-08-15 |
| DK67489D0 (da) | 1989-02-14 |
| NZ232491A (en) | 1992-05-26 |
| ES2058626T3 (es) | 1994-11-01 |
| DE69011150D1 (de) | 1994-09-08 |
| DK0383247T3 (da) | 1994-10-03 |
| NO900700D0 (no) | 1990-02-13 |
| ZA901079B (en) | 1990-11-28 |
| NO900700L (no) | 1990-08-15 |
| US5079243A (en) | 1992-01-07 |
| PT93133B (pt) | 1996-02-29 |
| IL93287A0 (en) | 1990-11-29 |
| NO174746B (no) | 1994-03-21 |
| EP0383247B1 (en) | 1994-08-03 |
| AU4935290A (en) | 1990-08-23 |
| IE900400L (en) | 1990-08-14 |
| DE69011150T2 (de) | 1994-12-08 |
| FI94956C (fi) | 1995-11-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: NOVO NORDISK A/S |