FI884418A0 - Hjaertskyddande aemne och ett terapeutiskt aemne foer ischemiska sjukdomar omfattande n-innehaollande heterocykliska foereningar, och ett foerfarande foer framstaellning av dessa foereningar. - Google Patents

Hjaertskyddande aemne och ett terapeutiskt aemne foer ischemiska sjukdomar omfattande n-innehaollande heterocykliska foereningar, och ett foerfarande foer framstaellning av dessa foereningar.

Info

Publication number: FI884418A0
Authority: FI; Finland
Prior art keywords: aemne; och ett; foer; ischemiska; hjaertskyddande
Prior art date: 1987-10-05

Application number

FI884418A

Other languages

English (en)

Other versions

FI884418A (fi

Inventor

Takao Takaya

Hisashi Takasugi

Kimio Esumi

Atsushi Kuno

Hiroyoshi Sakai

Kazuhiro Maeda

Yoshie Sakamoto

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-05

Filing date

1988-09-27

Publication date

1988-09-27

1988-04-21 Priority claimed from US07/184,195 external-priority patent/US4857527A/en

1988-09-27 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1988-09-27 Publication of FI884418A0 publication Critical patent/FI884418A0/fi

1988-10-04 Priority claimed from HU885132A external-priority patent/HUT51614A/hu

1989-04-06 Publication of FI884418A publication Critical patent/FI884418A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Materials For Medical Uses (AREA)

FI884418A 1987-10-05 1988-09-27 Hjaertskyddande aemne och ett terapeutiskt aemne foer ischemiska sjukdomar omfattande n-innehaollande heterocykliska foereningar, och ett foerfarande foer framstaellning av dessa foereningar. FI884418A (fi)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP25177187		1987-10-05
US07/184,195 US4857527A (en)	1985-12-12	1988-04-21	Morpholine containing pyridine compounds, compositions and use
HU885132A HUT51614A (en)	1985-12-12	1988-10-04	Process for producing cardio-protective and suitable for treating ischemic illnesses pharmaceutical compositions containing nitriferous heterocyclic compounds as active agent as well as for producing the active agents

Publications (2)

Publication Number	Publication Date
FI884418A0 true FI884418A0 (fi)	1988-09-27
FI884418A FI884418A (fi)	1989-04-06

Family

ID=27270050

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI884418A FI884418A (fi)	1987-10-05	1988-09-27	Hjaertskyddande aemne och ett terapeutiskt aemne foer ischemiska sjukdomar omfattande n-innehaollande heterocykliska foereningar, och ett foerfarande foer framstaellning av dessa foereningar.

Country Status (10)

Country	Link
EP (1)	EP0311322B1 (fi)
JP (1)	JPH01207234A (fi)
CN (1)	CN1041589A (fi)
AU (1)	AU621067B2 (fi)
CA (1)	CA1317296C (fi)
DE (1)	DE3882476T2 (fi)
DK (1)	DK554988A (fi)
ES (1)	ES2058301T3 (fi)
FI (1)	FI884418A (fi)
NO (1)	NO884399L (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8905526D0 (en) *	1989-03-10	1989-04-19	Fujisawa Pharmaceutical Co	N-containing heterocyclic compounds,processes for the preparation thereof and composition comprising the same
GB2266841A (en) *	1992-05-06	1993-11-17	Orion Yhtymae Oy	Compounds for use as anti-ischemic medicaments
US6384058B1 (en)	1997-12-11	2002-05-07	American Home Products Corporation	2,4,6-trisubstituted pryridines with estrogenic activity and methods for the solid phase synthesis thereof
US6503917B1 (en)	1998-12-10	2003-01-07	Wyeth, Five Giralda Farms	2,4,6-trisubstituted pyridines with estrogenic activity and methods for the solid phase synthesis thereof
JP2005524612A (ja) *	2001-12-06	2005-08-18	ファイブローゲン、インコーポレーテッド	内因性エリスロポエチン（ｅｐｏ）を増加させる方法
CN101664553B (zh) *	2001-12-06	2013-08-21	法布罗根股份有限公司	低氧诱导因子(HIF)α的稳定化
EP2295060B1 (en) *	2001-12-06	2018-10-31	Fibrogen, Inc.	Treatment or prevention of ischemic or hypoxic conditions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8530602D0 (en) *	1985-12-12	1986-01-22	Fujisawa Pharmaceutical Co	Heterocyclic compounds

1988
- 1988-09-27 FI FI884418A patent/FI884418A/fi not_active Application Discontinuation
- 1988-10-03 AU AU23338/88A patent/AU621067B2/en not_active Ceased
- 1988-10-03 JP JP63249593A patent/JPH01207234A/ja active Pending
- 1988-10-03 DE DE88309155T patent/DE3882476T2/de not_active Expired - Fee Related
- 1988-10-03 ES ES88309155T patent/ES2058301T3/es not_active Expired - Lifetime
- 1988-10-03 EP EP88309155A patent/EP0311322B1/en not_active Expired - Lifetime
- 1988-10-04 DK DK554988A patent/DK554988A/da not_active Application Discontinuation
- 1988-10-04 NO NO88884399A patent/NO884399L/no unknown
- 1988-10-04 CA CA000579295A patent/CA1317296C/en not_active Expired - Fee Related
- 1988-10-04 CN CN88109132A patent/CN1041589A/zh active Pending

Also Published As

Publication number	Publication date
FI884418A (fi)	1989-04-06
DK554988A (da)	1989-04-06
DE3882476T2 (de)	1993-11-11
EP0311322A2 (en)	1989-04-12
DK554988D0 (da)	1988-10-04
JPH01207234A (ja)	1989-08-21
DE3882476D1 (de)	1993-08-26
EP0311322B1 (en)	1993-07-21
EP0311322A3 (en)	1990-11-22
CA1317296C (en)	1993-05-04
AU621067B2 (en)	1992-03-05
CN1041589A (zh)	1990-04-25
NO884399L (no)	1989-04-06
NO884399D0 (no)	1988-10-04
ES2058301T3 (es)	1994-11-01
AU2333888A (en)	1989-06-01

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Legal Events

Date	Code	Title	Description
2004-08-31	FD	Application lapsed	Owner name: FUJISAWA PHARMACEUTICAL CO., LTD.