FI883553A0 - Foerfarande foer framstaellning av stabila oxapenem-3-karboxylsyror. - Google Patents
Foerfarande foer framstaellning av stabila oxapenem-3-karboxylsyror.Info
- Publication number
- FI883553A0 FI883553A0 FI883553A FI883553A FI883553A0 FI 883553 A0 FI883553 A0 FI 883553A0 FI 883553 A FI883553 A FI 883553A FI 883553 A FI883553 A FI 883553A FI 883553 A0 FI883553 A0 FI 883553A0
- Authority
- FI
- Finland
- Prior art keywords
- carbon
- pharmaceutically acceptable
- bonded
- single bonds
- groups
- Prior art date
Links
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
- CREMABGTGYGIQB-UHFFFAOYSA-N carbon carbon Chemical compound C.C CREMABGTGYGIQB-UHFFFAOYSA-N 0.000 abstract 3
- 239000011203 carbon fibre reinforced carbon Substances 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873725375 DE3725375A1 (de) | 1987-07-31 | 1987-07-31 | Stabile oxapenem-3-carbonsaeuren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI883553A0 true FI883553A0 (fi) | 1988-07-28 |
| FI883553A FI883553A (fi) | 1989-02-01 |
Family
ID=6332772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI883553A FI883553A (fi) | 1987-07-31 | 1988-07-28 | Foerfarande foer framstaellning av stabila oxapenem-3-karboxylsyror. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5096899A (fi) |
| EP (1) | EP0301394B1 (fi) |
| JP (1) | JPH0819135B2 (fi) |
| KR (1) | KR890002169A (fi) |
| CN (1) | CN1031533A (fi) |
| AT (1) | ATE95521T1 (fi) |
| AU (1) | AU618013B2 (fi) |
| CA (1) | CA1339450C (fi) |
| DD (1) | DD282012A5 (fi) |
| DE (2) | DE3725375A1 (fi) |
| DK (1) | DK425888A (fi) |
| ES (1) | ES2060628T3 (fi) |
| FI (1) | FI883553A (fi) |
| HU (1) | HU203355B (fi) |
| IE (1) | IE63026B1 (fi) |
| IL (1) | IL87254A (fi) |
| NO (1) | NO883188L (fi) |
| PH (1) | PH27226A (fi) |
| PT (1) | PT88118B (fi) |
| ZA (1) | ZA885571B (fi) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3833693A1 (de) * | 1988-10-04 | 1990-04-05 | Bayer Ag | Stabile oxapenem-3-carbonsaeuren und ihre verwendung als ss-lactamasehemmer |
| DE4027928A1 (de) * | 1990-09-04 | 1992-03-05 | Bayer Ag | Neue 2-tert.substituierte methyl-oxapenem-3-carbonsaeuren und -ester, verfahren zu ihrer herstellung und ihre verwendung |
| DE4142423A1 (de) * | 1991-12-20 | 1993-06-24 | Pfaendler Hans Rudolf | ((ls)-hydroxyalkyl)oxapenem-3-carbonsaeuren und ihre verwendung als betalactamasehemmer |
| AU9400401A (en) * | 2000-10-19 | 2002-04-29 | Amura Ltd | Pharmaceutical compositions containing oxapenem-3-carboxylic acids |
| EP1199077A1 (en) * | 2000-10-19 | 2002-04-24 | Amura Limited | Stable compositions of oxapenem-3-carboxylic acids by Co-lyophilisation with pharmaceutical carriers |
| GB2369358A (en) * | 2000-10-19 | 2002-05-29 | Amura Ltd | Oxapenems and pharmaceutical compositions thereof |
| GB0106428D0 (en) * | 2001-03-15 | 2001-05-02 | Amura Ltd | Antibacterial composition |
| AR039774A1 (es) * | 2002-05-01 | 2005-03-02 | Wyeth Corp | 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas |
| AR039475A1 (es) * | 2002-05-01 | 2005-02-23 | Wyeth Corp | 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa |
| WO2008141764A1 (en) | 2007-05-21 | 2008-11-27 | Hans Rudolf Pfaendler | Bactericidal anti-mrsa active pharmaceutical composition containing carbapenems |
| WO2009089380A2 (en) * | 2008-01-08 | 2009-07-16 | The Trustees Of Columbia University In The City Of New York | Methods for p2ry5 mediated regulation of hair growth and mutants thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1368236A (en) * | 1970-11-03 | 1974-09-25 | Glaxo Lab Ltd | Azetidinone derivatives and their preparation |
| AU498131B2 (en) * | 1974-02-26 | 1979-02-15 | Ciba-Geigy Ag | Production of cephems by cyclization |
| NZ177159A (en) * | 1974-04-20 | 1978-03-06 | Beecham Group Ltd | Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions |
| CA1136132A (en) * | 1975-02-17 | 1982-11-23 | Teruji Tsuji | Cyclization to form cephem ring and intermediates therefor |
| US4147864A (en) * | 1975-02-20 | 1979-04-03 | Ciba-Geigy Corporation | Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds |
| US4024152A (en) * | 1975-09-19 | 1977-05-17 | Eli Lilly And Company | 4-Dithio-3-imido-azetidin-2-ones |
| GB1529913A (en) * | 1976-02-04 | 1978-10-25 | Beecham Group Ltd | Beta-lactam compounds |
| GB1591438A (en) * | 1976-09-09 | 1981-06-24 | Glaxo Lab Ltd | Clavem derivatives |
| FR2364205A1 (fr) * | 1976-09-09 | 1978-04-07 | Glaxo Lab Ltd | Nouvelles betaines monocycliques et leur procede de preparation |
| GB1593275A (en) * | 1976-10-22 | 1981-07-15 | Glaxo Lab Ltd | Clavam derivatives |
| DK139377A (da) * | 1977-03-10 | 1978-09-11 | Beecham Group Ltd | Fremgangsmaade til fremstilling af ethere |
| US4260627A (en) * | 1978-10-24 | 1981-04-07 | Merck & Co., Inc. | 1-, 6- And 2-substituted-1-carba-2-penem-3-carboxylic acids |
| GB2045236A (en) * | 1979-03-26 | 1980-10-29 | Hoechst Uk Ltd | Oxapenem derivatives |
-
1987
- 1987-07-31 DE DE19873725375 patent/DE3725375A1/de not_active Withdrawn
-
1988
- 1988-07-18 NO NO88883188A patent/NO883188L/no unknown
- 1988-07-20 DE DE88111670T patent/DE3884705D1/de not_active Expired - Lifetime
- 1988-07-20 EP EP88111670A patent/EP0301394B1/de not_active Expired - Lifetime
- 1988-07-20 ES ES88111670T patent/ES2060628T3/es not_active Expired - Lifetime
- 1988-07-20 AT AT88111670T patent/ATE95521T1/de not_active IP Right Cessation
- 1988-07-26 AU AU20040/88A patent/AU618013B2/en not_active Expired
- 1988-07-27 PH PH37299A patent/PH27226A/en unknown
- 1988-07-27 JP JP63185711A patent/JPH0819135B2/ja not_active Expired - Fee Related
- 1988-07-27 PT PT88118A patent/PT88118B/pt not_active IP Right Cessation
- 1988-07-28 IL IL87254A patent/IL87254A/xx not_active IP Right Cessation
- 1988-07-28 DD DD88318411A patent/DD282012A5/de not_active IP Right Cessation
- 1988-07-28 FI FI883553A patent/FI883553A/fi not_active Application Discontinuation
- 1988-07-29 ZA ZA885571A patent/ZA885571B/xx unknown
- 1988-07-29 DK DK425888A patent/DK425888A/da not_active Application Discontinuation
- 1988-07-29 HU HU884042A patent/HU203355B/hu unknown
- 1988-07-29 IE IE234788A patent/IE63026B1/en not_active IP Right Cessation
- 1988-07-29 CA CA000573432A patent/CA1339450C/en not_active Expired - Fee Related
- 1988-07-30 CN CN88104689A patent/CN1031533A/zh active Pending
- 1988-07-30 KR KR1019880009849A patent/KR890002169A/ko not_active Application Discontinuation
-
1990
- 1990-08-24 US US07/574,573 patent/US5096899A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DK425888D0 (da) | 1988-07-29 |
| US5096899A (en) | 1992-03-17 |
| PT88118A (pt) | 1989-06-30 |
| PT88118B (pt) | 1995-03-01 |
| AU618013B2 (en) | 1991-12-12 |
| KR890002169A (ko) | 1989-04-08 |
| NO883188L (no) | 1989-02-01 |
| DK425888A (da) | 1989-02-01 |
| AU2004088A (en) | 1989-02-02 |
| HUT48889A (en) | 1989-07-28 |
| JPS6442484A (en) | 1989-02-14 |
| ATE95521T1 (de) | 1993-10-15 |
| EP0301394A1 (de) | 1989-02-01 |
| DE3884705D1 (de) | 1993-11-11 |
| IE882347L (en) | 1989-01-31 |
| DD282012A5 (de) | 1990-08-29 |
| NO883188D0 (no) | 1988-07-18 |
| IL87254A0 (en) | 1988-12-30 |
| PH27226A (en) | 1993-05-04 |
| ES2060628T3 (es) | 1994-12-01 |
| JPH0819135B2 (ja) | 1996-02-28 |
| DE3725375A1 (de) | 1989-02-09 |
| IE63026B1 (en) | 1995-03-22 |
| CN1031533A (zh) | 1989-03-08 |
| EP0301394B1 (de) | 1993-10-06 |
| ZA885571B (en) | 1989-04-26 |
| FI883553A (fi) | 1989-02-01 |
| IL87254A (en) | 1993-01-31 |
| CA1339450C (en) | 1997-09-09 |
| HU203355B (en) | 1991-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed | ||
| FD | Application lapsed |
Owner name: PFAENDLER, HANS RUDOLF |