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FI882979A - Microbiological process for the preparation of 4'-13 (S) -dihydro-4'-iodine doxorubicin - Google Patents

Microbiological process for the preparation of 4'-13 (S) -dihydro-4'-iodine doxorubicin Download PDF

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Publication number
FI882979A
FI882979A FI882979A FI882979A FI882979A FI 882979 A FI882979 A FI 882979A FI 882979 A FI882979 A FI 882979A FI 882979 A FI882979 A FI 882979A FI 882979 A FI882979 A FI 882979A
Authority
FI
Finland
Prior art keywords
dihydro
preparation
microbiological process
doxorubicin
iodine
Prior art date
Application number
FI882979A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI90566B (en
FI882979A0 (en
FI90566C (en
Inventor
Giuseppe Cassinelli
Teresa Bordoni
Sergio Merli
Giovanni Rivola
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Priority to FI882979A priority Critical patent/FI90566C/en
Publication of FI882979A0 publication Critical patent/FI882979A0/en
Publication of FI882979A publication Critical patent/FI882979A/en
Publication of FI90566B publication Critical patent/FI90566B/en
Application granted granted Critical
Publication of FI90566C publication Critical patent/FI90566C/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

The invention relates to a microbial stereoselective reduction method for production of 4'-deoxy-13(S)-dihydro- 4'-iododoxorubicin with formula II, and pharmaceutically acceptable salts thereof. The compounds according to the invention are antitumoral substances. <IMAGE>
FI882979A 1988-06-22 1988-06-22 Microbiological method for the preparation of 4'-13 (S) -dihydro-4'-iodidoxorubicin FI90566C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI882979A FI90566C (en) 1988-06-22 1988-06-22 Microbiological method for the preparation of 4'-13 (S) -dihydro-4'-iodidoxorubicin

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI882979A FI90566C (en) 1988-06-22 1988-06-22 Microbiological method for the preparation of 4'-13 (S) -dihydro-4'-iodidoxorubicin
FI882979 1988-06-22

Publications (4)

Publication Number Publication Date
FI882979A0 FI882979A0 (en) 1988-06-22
FI882979A true FI882979A (en) 1989-12-23
FI90566B FI90566B (en) 1993-11-15
FI90566C FI90566C (en) 1994-02-25

Family

ID=8526694

Family Applications (1)

Application Number Title Priority Date Filing Date
FI882979A FI90566C (en) 1988-06-22 1988-06-22 Microbiological method for the preparation of 4'-13 (S) -dihydro-4'-iodidoxorubicin

Country Status (1)

Country Link
FI (1) FI90566C (en)

Also Published As

Publication number Publication date
FI90566B (en) 1993-11-15
FI882979A0 (en) 1988-06-22
FI90566C (en) 1994-02-25

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: PHARMACIA & UPJOHN S.P.A.

MM Patent lapsed

Owner name: PHARMACIA & UPJOHN S., P.A.