FI882059A0 - Process for the preparation of foreign proteins in Streptomyces cells - Google Patents

Process for the preparation of foreign proteins in Streptomyces cells

Info

Publication number: FI882059A0
Authority: FI; Finland
Prior art keywords: preparation; foreign proteins; streptomyces cells; streptomyces; cells
Prior art date: 1987-05-05

Application number

FI882059A

Other languages

Finnish (fi)

Swedish (sv)

Other versions

FI97549B (en

FI97549C (en

FI882059A (en

Inventor

Klaus-Peter Koller

Guenther Johannes Riess

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-05-05

Filing date

1988-05-03

Publication date

1988-05-03

1988-05-03 Application filed by Hoechst Ag filed Critical Hoechst Ag

1988-05-03 Publication of FI882059A0 publication Critical patent/FI882059A0/en

1988-11-06 Publication of FI882059A publication Critical patent/FI882059A/en

1996-09-30 Publication of FI97549B publication Critical patent/FI97549B/en

1997-01-10 Application granted granted Critical

1997-01-10 Publication of FI97549C publication Critical patent/FI97549C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)

FI882059A 1987-05-05 1988-05-03 Method for the production of foreign proteins in Streptomycess cells FI97549C (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3714866		1987-05-05
DE19873714866 DE3714866A1 (en)	1987-05-05	1987-05-05	METHOD FOR THE PRODUCTION OF FOREIGN PROTEINS IN STREPTOMYCETES

Publications (4)

Publication Number	Publication Date
FI882059A0 true FI882059A0 (en)	1988-05-03
FI882059A FI882059A (en)	1988-11-06
FI97549B FI97549B (en)	1996-09-30
FI97549C FI97549C (en)	1997-01-10

Family

ID=6326841

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI882059A FI97549C (en)	1987-05-05	1988-05-03	Method for the production of foreign proteins in Streptomycess cells

Country Status (19)

Country	Link
EP (1)	EP0289936B1 (en)
JP (1)	JP2671260B2 (en)
KR (1)	KR970001235B1 (en)
CN (1)	CN1029989C (en)
AR (1)	AR241658A1 (en)
AT (1)	ATE94905T1 (en)
AU (1)	AU612144B2 (en)
CA (1)	CA1338338C (en)
DE (2)	DE3714866A1 (en)
DK (1)	DK175525B1 (en)
ES (1)	ES2045004T3 (en)
FI (1)	FI97549C (en)
HU (1)	HU204094B (en)
IE (1)	IE62522B1 (en)
IL (1)	IL86277A0 (en)
NO (1)	NO178036C (en)
NZ (1)	NZ224464A (en)
PT (1)	PT87400B (en)
ZA (1)	ZA883168B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5426036A (en) *	1987-05-05	1995-06-20	Hoechst Aktiengesellschaft	Processes for the preparation of foreign proteins in streptomycetes
DE4012818A1 (en)	1990-04-21	1991-10-24	Hoechst Ag	METHOD FOR THE PRODUCTION OF FOREIGN PROTEINS IN STREPTOMYCETES
DE58909556D1 (en) *	1988-11-03	1996-02-15	Hoechst Ag	Process for the production of an insulin precursor in streptomycetes
DE3844211A1 (en) *	1988-12-29	1990-07-05	Hoechst Ag	NEW INSULINE DERIVATIVES, THE PROCESS FOR THEIR PRODUCTION, THEIR USE AND A PHARMACEUTICAL PREPARATION CONTAINING THEM
DE3936876A1 (en) *	1989-11-06	1991-05-23	Hoechst Ag	NEW INSULINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND A PHARMACEUTICAL PREPARATION CONTAINING THE SAME

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3331860A1 (en) *	1983-09-03	1985-03-21	Hoechst Ag, 6230 Frankfurt	Process for the preparation of tendamistat
DE3418274A1 (en) *	1984-05-17	1985-11-21	Hoechst Ag, 6230 Frankfurt	SIGNAL PEPTIDE FOR THE EXCRETION OF PEPTIDES IN STREPTOMYCETS
ATE63757T1 (en) *	1985-03-28	1991-06-15	Chiron Corp	EXPRESSION THROUGH USE OF FUSION GENES FOR PROTEIN PRODUCTION.
DE3707150A1 (en) *	1987-03-06	1988-09-15	Hoechst Ag	TENDAMISTAT DERIVATIVES
DE58909556D1 (en) *	1988-11-03	1996-02-15	Hoechst Ag	Process for the production of an insulin precursor in streptomycetes

1987
- 1987-05-05 DE DE19873714866 patent/DE3714866A1/en not_active Withdrawn
1988
- 1988-04-28 EP EP88106786A patent/EP0289936B1/en not_active Expired - Lifetime
- 1988-04-28 DE DE88106786T patent/DE3884261D1/en not_active Expired - Lifetime
- 1988-04-28 ES ES88106786T patent/ES2045004T3/en not_active Expired - Lifetime
- 1988-04-28 AT AT88106786T patent/ATE94905T1/en not_active IP Right Cessation
- 1988-05-03 KR KR1019880005131A patent/KR970001235B1/en not_active IP Right Cessation
- 1988-05-03 AR AR88310742A patent/AR241658A1/en active
- 1988-05-03 NZ NZ224464A patent/NZ224464A/en unknown
- 1988-05-03 FI FI882059A patent/FI97549C/en not_active IP Right Cessation
- 1988-05-04 AU AU15559/88A patent/AU612144B2/en not_active Expired
- 1988-05-04 CA CA000565869A patent/CA1338338C/en not_active Expired - Lifetime
- 1988-05-04 IL IL86277A patent/IL86277A0/en not_active IP Right Cessation
- 1988-05-04 IE IE133888A patent/IE62522B1/en not_active IP Right Cessation
- 1988-05-04 DK DK198802416A patent/DK175525B1/en not_active IP Right Cessation
- 1988-05-04 PT PT87400A patent/PT87400B/en not_active IP Right Cessation
- 1988-05-04 ZA ZA883168A patent/ZA883168B/en unknown
- 1988-05-04 NO NO881942A patent/NO178036C/en unknown
- 1988-05-04 HU HU882276A patent/HU204094B/en unknown
- 1988-05-04 CN CN88102568A patent/CN1029989C/en not_active Expired - Lifetime
- 1988-05-06 JP JP63110295A patent/JP2671260B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
FI97549B (en)	1996-09-30
HUT46941A (en)	1988-12-28
CN88102568A (en)	1988-11-23
ZA883168B (en)	1989-11-29
FI97549C (en)	1997-01-10
CN1029989C (en)	1995-10-11
KR880014102A (en)	1988-12-22
PT87400B (en)	1992-09-30
NO881942L (en)	1988-11-07
JPS63301793A (en)	1988-12-08
DE3714866A1 (en)	1988-11-24
NO881942D0 (en)	1988-05-04
IL86277A0 (en)	1988-11-15
ES2045004T3 (en)	1994-01-16
FI882059A (en)	1988-11-06
DK241688D0 (en)	1988-05-04
NZ224464A (en)	1990-02-26
IE62522B1 (en)	1995-02-08
ATE94905T1 (en)	1993-10-15
CA1338338C (en)	1996-05-21
PT87400A (en)	1989-05-31
KR970001235B1 (en)	1997-02-04
JP2671260B2 (en)	1997-10-29
DE3884261D1 (en)	1993-10-28
IE881338L (en)	1988-11-05
EP0289936B1 (en)	1993-09-22
NO178036B (en)	1995-10-02
EP0289936A3 (en)	1989-11-23
EP0289936A2 (en)	1988-11-09
DK241688A (en)	1988-11-06
AR241658A1 (en)	1992-10-30
HU204094B (en)	1991-11-28
AU1555988A (en)	1988-11-10
NO178036C (en)	1996-01-10
DK175525B1 (en)	2004-11-22
AU612144B2 (en)	1991-07-04

Publication	Publication Date	Title
FI893542A0 (en)	1989-07-24	Enzyme electrodes and process for their preparation
PT86600A (en)	1988-02-01	PROCESS FOR THE PREPARATION OF ANTICOAGULANT PEPTIDES
IL91412A0 (en)	1990-04-29	Process and solution for the lyophilization of blood cells
EP0243929A3 (en)	1989-10-11	Polypeptide and protein derivatives and process for their preparation
FI98830B (en)	1997-05-15	Process for the preparation of bifunctional proteins
PT87688A (en)	1988-07-01	HYBRID PROTEIN C AND METHOD FOR ITS PREPARATION
AU2487788A (en)	1989-04-17	Pathogenesis-related proteins in plants
FI91961C (en)	1994-09-12	Process for the preparation of (S) -ethyl-2-oxo-1-pyrrolidineacetamide
EP0362758A3 (en)	1990-09-12	Electro-insertion of proteins into animal cell membranes
FI95914C (en)	1996-04-10	Polypeptide derivatives and process for their preparation
EP0295859A3 (en)	1990-04-18	Production of proteins in active forms
NO875479L (en)	1989-07-03	PROCEDURE FOR SETTING ELECTRODES IN ELECTROLYCLE CELLS.
FI882059A (en)	1988-11-06	Process for the preparation of foreign proteins in Streptomyces cells
PT87857A (en)	1988-07-01	PROCESS FOR THE PREPARATION OF NOVEL IMMUNOSSUPRESSANT PEPTIDES
IL95711A0 (en)	1991-06-30	Anticoagulant and anthelmintic proteins and methods for the production and use of the same
AU2810089A (en)	1989-06-14	Production of proteins in plants
FI91526B (en)	1994-03-31	Process for the preparation of novel therapeutically useful 3-aryl-5-alkylsulfinyl and sulfonyl-4H-1,2,4-triazoles
GB8713559D0 (en)	1987-07-15	Structural proteins
PT87732A (en)	1988-07-01	PROCESS FOR THE PREPARATION OF (E) - (P-FLUOROPHENETHYL) -3-FLUOROALLYLAMINE
IL90773A0 (en)	1990-01-18	Process for the production of proteins
AU1501088A (en)	1988-10-27	Production of proteins in active forms
KR890701740A (en)	1989-12-21	Method for manufacturing novel protein sweetener
DE3675631D1 (en)	1990-12-20	IN VITRO CULTURE PROCESS.
SE8804317A0 (en)	1990-05-30	Compositions for reducing phlebectasia and process for their preparation
AU1763188A (en)	1988-12-15	Recovery of proteins in active form

Legal Events

Date	Code	Title	Description
1996-09-02	BB	Publication of examined application
1998-05-03	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: HOECHST AKTIENGESELLSCHAFT