FI875666A0 - Menetelmä terapeuttisesti aktiivisen kinoliiniyhdisteen valmistamiseksi - Google Patents

Menetelmä terapeuttisesti aktiivisen kinoliiniyhdisteen valmistamiseksi

Info

Publication number: FI875666A0
Authority: FI; Finland
Prior art keywords: preparation; therapeutically active; quinoline compound; active quinoline; compound
Prior art date: 1986-12-23

Application number

FI875666A

Other languages

English (en)

Swedish (sv)

Other versions

FI875666L (fi

FI90768C (fi

FI90768B (fi

Inventor

Arthur Page Phillips

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-23

Filing date

1987-12-22

Publication date

1987-12-22

1987-12-22 Application filed by Wellcome Found filed Critical Wellcome Found

1987-12-22 Publication of FI875666A0 publication Critical patent/FI875666A0/fi

1988-06-24 Publication of FI875666L publication Critical patent/FI875666L/fi

1993-12-15 Application granted granted Critical

1993-12-15 Publication of FI90768B publication Critical patent/FI90768B/fi

1994-03-25 Publication of FI90768C publication Critical patent/FI90768C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Quinoline Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Superconductors And Manufacturing Methods Therefor (AREA)
Secondary Cells (AREA)
Carbon And Carbon Compounds (AREA)

FI875666A 1986-12-23 1987-12-22 Menetelmä terapeuttisesti aktiivisen kinoliiniyhdisteen valmistamiseksi FI90768C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB868630702A GB8630702D0 (en)	1986-12-23	1986-12-23	Quinoline compound
GB8630702		1986-12-23

Publications (4)

Publication Number	Publication Date
FI875666A0 true FI875666A0 (fi)	1987-12-22
FI875666L FI875666L (fi)	1988-06-24
FI90768B FI90768B (fi)	1993-12-15
FI90768C FI90768C (fi)	1994-03-25

Family

ID=10609475

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI875666A FI90768C (fi)	1986-12-23	1987-12-22	Menetelmä terapeuttisesti aktiivisen kinoliiniyhdisteen valmistamiseksi

Country Status (22)

Country	Link
US (1)	US4937248A (fi)
EP (1)	EP0272910B1 (fi)
JP (1)	JPS63166866A (fi)
KR (1)	KR880007514A (fi)
AT (1)	ATE65993T1 (fi)
AU (1)	AU594220B2 (fi)
CA (1)	CA1318671C (fi)
DE (1)	DE3772015D1 (fi)
DK (1)	DK163429C (fi)
ES (1)	ES2029842T3 (fi)
FI (1)	FI90768C (fi)
GB (1)	GB8630702D0 (fi)
GR (1)	GR3002445T3 (fi)
HU (1)	HU196991B (fi)
IE (1)	IE60619B1 (fi)
IL (1)	IL84917A (fi)
MX (1)	MX9203788A (fi)
MY (1)	MY102277A (fi)
NZ (1)	NZ223036A (fi)
PH (1)	PH23448A (fi)
PT (1)	PT86448B (fi)
ZA (1)	ZA879615B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5166160A (en) *	1986-12-23	1992-11-24	Burroughs Wellcome Co.	Quinoline compound
GB8820174D0 (en) *	1988-08-25	1988-09-28	Wellcome Found	Quinoline compound
ID24373A (id) *	1997-09-24	2000-07-13	Orion Corp	Biester dari 1-oksa, aza dan tianaftelan-2-on sebagai inhibitor fosfolamban
CA2378298A1 (en)	1999-08-27	2001-03-08	Lawrence G. Hamann	8-substituted-6-trifluoromethyl-9-pyrido¬3,2-g\|quinoline compounds as androgen receptor modulators
US6566372B1 (en)	1999-08-27	2003-05-20	Ligand Pharmaceuticals Incorporated	Bicyclic androgen and progesterone receptor modulator compounds and methods
CZ2002711A3 (cs)	1999-08-27	2003-11-12	Ligand Pharmaceuticals Incorporated	Modulátory androgenních receptorů, způsoby jejich výroby a způsoby jejich použití
US6593493B1 (en)	1999-09-14	2003-07-15	Ligand Pharmaceuticals, Inc.	RXR modulators with improved pharmacologic profile
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
AU2004266160A1 (en)	2003-08-22	2005-03-03	Ligand Pharmaceuticals Incorporated	6-cycloamino-2-quinolinone derivatives as androgen receptor modulator compounds
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2170930B3 (en)	2007-06-04	2013-10-02	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011522828A (ja)	2008-06-04	2011-08-04	シナジーファーマシューティカルズインコーポレイテッド	胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
AU2009270833B2 (en)	2008-07-16	2015-02-19	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
CN103764672A (zh)	2011-03-01	2014-04-30	辛纳吉制药公司	制备鸟苷酸环化酶c激动剂的方法
EP2958577A2 (en)	2013-02-25	2015-12-30	Synergy Pharmaceuticals Inc.	Guanylate cyclase receptor agonists for use in colonic cleansing
WO2014151200A2 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
CA2905438A1 (en)	2013-03-15	2014-09-25	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase and their uses
JP6606491B2 (ja)	2013-06-05	2019-11-13	シナジーファーマシューティカルズインコーポレイテッド	グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
US20160184387A1 (en)	2013-08-09	2016-06-30	Dominique Charmot	Compounds and methods for inhibiting phosphate transport
US20200368223A1 (en)	2019-05-21	2020-11-26	Ardelyx, Inc.	Methods for inhibiting phosphate transport

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2616855A (en) *	1948-01-15	1952-11-04	Procter & Gamble	Detergent composition
US4329347A (en) *	1978-02-17	1982-05-11	Boehringer Ingelheim Gmbh	Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril
JPS5777676A (en) *	1980-10-31	1982-05-15	Otsuka Pharmaceut Co Ltd	Carbostyril derivative
PT79699B (en) *	1983-12-22	1986-12-10	Pfizer	Process for preparing quinolone inotropic agents
PT80533B (en) *	1984-05-29	1987-04-06	Pfizer	Process for preparing quinolone inotropic agents
US4760064A (en) *	1984-12-18	1988-07-26	Otsuka Pharmaceutical Co., Ltd.	Carbostyril compounds, compositions containing same and processes for preparing same
US4845100A (en) *	1985-04-12	1989-07-04	Otsuka Pharmaceutical Co., Ltd.	Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same
FR2580646A1 (fr) *	1985-04-19	1986-10-24	Synthelabo	Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique
GB8529362D0 (en) *	1985-11-28	1986-01-02	Pfizer Ltd	Quinolone cardiac stimulants
DK111387A (da) *	1986-03-05	1987-09-06	Otsuka Pharma Co Ltd	Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
ES2053480T3 (es) *	1986-07-31	1994-08-01	Otsuka Pharma Co Ltd	Un procedimiento para preparar un derivado de carboestirilo.

1986
- 1986-12-23 GB GB868630702A patent/GB8630702D0/en active Pending
1987
- 1987-12-21 MY MYPI87003231A patent/MY102277A/en unknown
- 1987-12-21 US US07/135,654 patent/US4937248A/en not_active Expired - Fee Related
- 1987-12-22 JP JP62325121A patent/JPS63166866A/ja active Pending
- 1987-12-22 IL IL84917A patent/IL84917A/xx not_active IP Right Cessation
- 1987-12-22 PH PH36289A patent/PH23448A/en unknown
- 1987-12-22 DK DK680887A patent/DK163429C/da not_active IP Right Cessation
- 1987-12-22 KR KR870014675A patent/KR880007514A/ko not_active Ceased
- 1987-12-22 FI FI875666A patent/FI90768C/fi not_active IP Right Cessation
- 1987-12-22 HU HU875962A patent/HU196991B/hu not_active IP Right Cessation
- 1987-12-22 AT AT87311275T patent/ATE65993T1/de active
- 1987-12-22 PT PT86448A patent/PT86448B/pt not_active IP Right Cessation
- 1987-12-22 IE IE349087A patent/IE60619B1/en not_active IP Right Cessation
- 1987-12-22 AU AU82933/87A patent/AU594220B2/en not_active Ceased
- 1987-12-22 EP EP87311275A patent/EP0272910B1/en not_active Expired - Lifetime
- 1987-12-22 ZA ZA879615A patent/ZA879615B/xx unknown
- 1987-12-22 DE DE8787311275T patent/DE3772015D1/de not_active Expired - Fee Related
- 1987-12-22 NZ NZ223036A patent/NZ223036A/en unknown
- 1987-12-22 CA CA000555175A patent/CA1318671C/en not_active Expired - Fee Related
- 1987-12-22 ES ES198787311275T patent/ES2029842T3/es not_active Expired - Lifetime
1991
- 1991-08-08 GR GR91401029T patent/GR3002445T3/el unknown
1992
- 1992-06-29 MX MX9203788A patent/MX9203788A/es unknown

Also Published As

Publication number	Publication date
IL84917A (en)	1991-08-16
DK680887A (da)	1988-06-24
MY102277A (en)	1992-05-15
DE3772015D1 (de)	1991-09-12
PT86448A (en)	1988-01-01
US4937248A (en)	1990-06-26
DK680887D0 (da)	1987-12-22
ATE65993T1 (de)	1991-08-15
IE873490L (en)	1988-06-23
IL84917A0 (en)	1988-06-30
NZ223036A (en)	1990-11-27
PT86448B (pt)	1990-11-20
CA1318671C (en)	1993-06-01
FI875666L (fi)	1988-06-24
IE60619B1 (en)	1994-07-27
FI90768C (fi)	1994-03-25
HU196991B (en)	1989-02-28
KR880007514A (ko)	1988-08-27
ZA879615B (en)	1989-08-30
PH23448A (en)	1989-08-07
GB8630702D0 (en)	1987-02-04
EP0272910B1 (en)	1991-08-07
AU8293387A (en)	1988-06-23
DK163429C (da)	1992-07-20
HUT45984A (en)	1988-09-28
MX9203788A (es)	1992-07-01
AU594220B2 (en)	1990-03-01
FI90768B (fi)	1993-12-15
JPS63166866A (ja)	1988-07-11
EP0272910A1 (en)	1988-06-29
ES2029842T3 (es)	1992-10-01
GR3002445T3 (en)	1992-12-30
DK163429B (da)	1992-03-02

Publication	Publication Date	Title
FI875666A0 (fi)	1987-12-22	Menetelmä terapeuttisesti aktiivisen kinoliiniyhdisteen valmistamiseksi
DK658787A (da)	1988-07-31	Mycophenolsyrederivater
DK0674513T3 (da)	1997-03-17	Retroviral protease-inhiberende forbindelser
FI892497A0 (fi)	1989-05-23	Menetelmä terapeuttisesti aktiivisten bentsamidijohdannaisten valmistamiseksi
FI885594A0 (fi)	1988-12-01	Tiazolidindioner anvaendbara foer saenkande av blodsockerhalten samt atherosklerosis hindrande medel.
NO177638C (no)	1995-10-25	Analogifremgangsmåte for fremstilling av en terapeutisk aktiv spiroforbindelse
DE3851279D1 (de)	1994-10-06	Organische Salze von Physostigminderivaten.
NO173445C (no)	1993-12-15	Analogifremgansmaate for fremstilling av terapeutisk aktive kinolinkarboksylyrederivater
FI931855A0 (fi)	1993-04-23	Farmaceutisk sammansaettning som innehaoller kinolin- och kinazolinderivat samt nya foereningar daerfoer
SE9100920D0 (sv)	1991-03-27	New active compounds
DE3665711D1 (de)	1989-10-26	Novel guanidinomethylbenzoic acid derivatives
NO177141C (no)	1995-07-26	Analogifremgangsmåte for fremstilling av terapeutisk aktive aminosyreantagonister
NO173444C (no)	1993-12-15	Analogifremgangsmaate til fremstilling av terapeutisk aktive 4-(4'- fluorfenyl-)-tienopyridin-derivater
ES2054007T3 (es)	1994-08-01	Compuesto de quinolina.
NO173991C (no)	1994-03-02	Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2,5-ditiazocin-derivater
DE3677465D1 (de)	1991-03-14	N-glykolylneuraminsaeurederivat.
ATE146472T1 (de)	1997-01-15	Umwandlungsverfahren von lorabef dihydrate in loracarbef monohydrate
FI851688A0 (fi)	1985-04-29	Foerfarande foer framstaellning av kefalosporinfoereningar.
ATE77373T1 (de)	1992-07-15	Verfahren zur herstellung von chinolinsaeurederivaten.

Legal Events

Date	Code	Title	Description
1993-11-16	BB	Publication of examined application
1996-07-11	MM	Patent lapsed
2004-08-31	MM	Patent lapsed	Owner name: THE WELLCOME FOUNDATION LIMITED