FI875438A7 - Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. - Google Patents

Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. Download PDF

Info

Publication number: FI875438A7
Authority: FI; Finland
Prior art keywords: pyrrolobenzimidazoler; nya; foerfarande foer; foer framstaellning; framstaellning
Prior art date: 1986-12-11

Application number

FI875438A

Other languages

English (en)

Finnish (fi)

Other versions

FI875438A0 (fi

Inventor

Walter-Gunar Friebe

Alfred Mertens

Klaus Strein

Erwin Boehm

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-11

Filing date

1987-12-10

Publication date

1988-06-12

1987-12-10 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1987-12-10 Publication of FI875438A0 publication Critical patent/FI875438A0/fi

1988-06-12 Publication of FI875438A7 publication Critical patent/FI875438A7/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Cardiology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

FI875438A 1986-12-11 1987-12-10 Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. FI875438A7 (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19863642315 DE3642315A1 (de)	1986-12-11	1986-12-11	Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel

Publications (2)

Publication Number	Publication Date
FI875438A0 FI875438A0 (fi)	1987-12-10
FI875438A7 true FI875438A7 (fi)	1988-06-12

Family

ID=6315954

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI875438A FI875438A7 (fi)	1986-12-11	1987-12-10	Foerfarande foer framstaellning av nya pyrrolobenzimidazoler.

Country Status (13)

Country	Link
US (1)	US4863945A (da)
EP (1)	EP0271040A3 (da)
JP (1)	JPS63162692A (da)
KR (1)	KR880007536A (da)
AU (1)	AU8245087A (da)
DD (1)	DD267047A5 (da)
DE (1)	DE3642315A1 (da)
DK (1)	DK650187A (da)
FI (1)	FI875438A7 (da)
HU (1)	HU200339B (da)
IL (1)	IL84589A0 (da)
PT (1)	PT86331B (da)
ZA (1)	ZA879166B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5206240A (en) *	1989-12-08	1993-04-27	Merck & Co., Inc.	Nitrogen-containing spirocycles
DE4027592A1 (de) *	1990-08-31	1992-03-05	Beiersdorf Ag	Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5434163A (en) *	1993-05-14	1995-07-18	The Medical College Of Pennsylvania	Treatment of Cryptococcus neoformans infection
US6184226B1 (en)	1998-08-28	2001-02-06	Scios Inc.	Quinazoline derivatives as inhibitors of P-38 α
US6878714B2 (en) *	2001-01-12	2005-04-12	Amgen Inc.	Substituted alkylamine derivatives and methods of use
US6995162B2 (en)	2001-01-12	2006-02-07	Amgen Inc.	Substituted alkylamine derivatives and methods of use
EP1598353A1 (en) *	2004-05-17	2005-11-23	Boehringer Ingelheim International GmbH	Pyrrolobenzimidazolones and their use as antiproliferative agents
US7285569B2 (en)	2004-09-24	2007-10-23	Hoff Hoffmann-La Roche Inc.	Tricycles, their manufacture and use as pharmaceutical agents
US20060142247A1 (en) *	2004-12-17	2006-06-29	Guy Georges	Tricyclic heterocycles
KR20070113286A (ko) *	2005-04-14	2007-11-28	에프. 호프만-라 로슈 아게	아미노피라졸 유도체, 이의 제조 및 약학 제제로서의 용도
CN101160312A (zh) *	2005-04-14	2008-04-09	霍夫曼-拉罗奇有限公司	三环吡咯衍生物、它们的制备和作为药剂的应用
BRPI0619955A2 (pt) *	2005-12-15	2011-10-25	Hoffmann La Roche	derivados tricìclicos da lactama, sua produção e seus usos como agentes farmacêuticos
US20090291968A1 (en) *	2006-03-23	2009-11-26	Guy Georges	Substituted indazole derivatives, their manufacture and use as pharmaceutical agents
WO2008063888A2 (en)	2006-11-22	2008-05-29	Plexxikon, Inc.	Compounds modulating c-fms and/or c-kit activity and uses therefor
SG183036A1 (en)	2007-07-17	2012-08-30	Plexxikon Inc	Compounds and methods for kinase modulation, and indications therefor
AU2010232670B2 (en)	2009-04-03	2015-07-09	F. Hoffmann-La Roche Ag	Propane- I-sulfonic acid {3- [5- (4 -chloro-phenyl) -1H-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof
US8329724B2 (en)	2009-08-03	2012-12-11	Hoffmann-La Roche Inc.	Process for the manufacture of pharmaceutically active compounds
ES2633317T3 (es)	2009-11-06	2017-09-20	Plexxikon, Inc.	Compuestos y métodos para la modulación de quinasas, e indicaciones para ello
CN103517710B (zh)	2011-02-07	2017-05-31	普莱希科公司	用于激酶调节的化合物
TWI558702B (zh)	2011-02-21	2016-11-21	普雷辛肯公司	醫藥活性物質的固態形式
US9150570B2 (en)	2012-05-31	2015-10-06	Plexxikon Inc.	Synthesis of heterocyclic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL144822B1 (en) *	1984-05-12	1988-07-30	Boehringer Mannheim Gmbh	Method of obtaining novel pyrolobenzimidazoles
DE3445669A1 (de) *	1984-12-14	1986-06-19	Boehringer Mannheim Gmbh, 6800 Mannheim	Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3501497A1 (de) *	1985-01-18	1986-07-24	Boehringer Mannheim Gmbh, 6800 Mannheim	Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3531678A1 (de) *	1985-09-05	1987-03-12	Boehringer Mannheim Gmbh	Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

1986
- 1986-12-11 DE DE19863642315 patent/DE3642315A1/de not_active Withdrawn
1987
- 1987-11-25 IL IL84589A patent/IL84589A0/xx unknown
- 1987-12-07 DD DD87310045A patent/DD267047A5/de not_active IP Right Cessation
- 1987-12-07 EP EP87118046A patent/EP0271040A3/de not_active Withdrawn
- 1987-12-07 ZA ZA879166A patent/ZA879166B/xx unknown
- 1987-12-09 JP JP62309792A patent/JPS63162692A/ja active Pending
- 1987-12-10 FI FI875438A patent/FI875438A7/fi not_active Application Discontinuation
- 1987-12-10 HU HU875579A patent/HU200339B/hu not_active IP Right Cessation
- 1987-12-10 US US07/131,367 patent/US4863945A/en not_active Expired - Fee Related
- 1987-12-10 DK DK650187A patent/DK650187A/da not_active Application Discontinuation
- 1987-12-10 PT PT86331A patent/PT86331B/pt not_active IP Right Cessation
- 1987-12-11 KR KR870014131A patent/KR880007536A/ko not_active Withdrawn
- 1987-12-11 AU AU82450/87A patent/AU8245087A/en not_active Abandoned

Also Published As

Publication number	Publication date
IL84589A0 (en)	1988-04-29
DK650187D0 (da)	1987-12-10
HUT47278A (en)	1989-02-28
KR880007536A (ko)	1988-08-27
EP0271040A2 (de)	1988-06-15
DD267047A5 (de)	1989-04-19
HU200339B (en)	1990-05-28
ZA879166B (en)	1988-06-14
DE3642315A1 (de)	1988-06-23
FI875438A0 (fi)	1987-12-10
PT86331B (pt)	1990-11-07
JPS63162692A (ja)	1988-07-06
PT86331A (de)	1988-01-01
DK650187A (da)	1988-06-12
AU8245087A (en)	1988-06-16
EP0271040A3 (de)	1989-11-02
US4863945A (en)	1989-09-05

Publication	Publication Date	Title
FI873058A7 (fi)	1988-01-12	Foerfarande foer framstaellning av nya difosfonsyraderivat.
FI875096A7 (fi)	1988-05-22	Foerfarande foer framstaellning av nya substituerade alkandifosfonsyror.
FI872878L (fi)	1987-12-31	Foerfarande foer framstaellning av nya algininsyraestrar.
FI873339L (fi)	1988-02-02	Foerfarande foer framstaellning av nya difosfonsyraderivat.
FI874702L (fi)	1988-04-28	Foerfarande foer framstaellning av nya benzimidazolderivater.
FI883056L (fi)	1988-06-23	Nya former av kolonistimulerande faktor-1.
FI874287A0 (fi)	1987-09-30	Nya lymfokinpeptider.
FI874388A7 (fi)	1988-04-08	Foerfarande foer framstaellning av nya 5-alkylbensimidazoler.
FI875257A7 (fi)	1988-05-30	Foerfarande foer framstaellning av nya difosfonsyraderivat.
FI873704A0 (fi)	1987-08-26	Nya ksantinderivat.
FI871406A0 (fi)	1987-03-31	Foerfarande foer framstaellning av nya aminosyraderivat.
FI870871A7 (fi)	1987-08-29	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara peptidderivat.
FI875438A7 (fi)	1988-06-12	Foerfarande foer framstaellning av nya pyrrolobenzimidazoler.
FI871981A7 (fi)	1987-11-07	Nya dopamin- -hydroxylas-inhibitorer.
FI873920A0 (fi)	1987-09-10	Foereskriftsstruktur foer infoering av nya element i kretsstruktur-syntesproceduren.
FI873193A0 (fi)	1987-07-20	Nya 18-fenylestranderivat.
FI873593A0 (fi)	1987-08-20	Nya applikationsformer foer -interferon.
FI883257A0 (fi)	1988-07-07	Nya peptider.
FI871445A7 (fi)	1987-10-05	Foerfarande foer framstaellning av nya spergualinderivat.
FI872571A0 (fi)	1987-06-09	Nya antracykliner.
FI872489L (fi)	1987-12-07	Foerfarande foer framstaellning av nya aralkylimidazolderivat.
FI875095A7 (fi)	1988-05-22	Foerfarande foer framstaellning av nya substituerade aminometandifosfonsyror.
FI875766A0 (fi)	1987-12-30	Foerfarande foer framstaellning av nya pyrimidinderivat.
FI893155A0 (fi)	1989-06-28	Nya foereningar.
FI871094A0 (fi)	1987-03-12	Nya monocykliska estrar.

Legal Events

Date	Code	Title	Description
2004-08-31	FD	Application lapsed	Owner name: BOEHRINGER MANNHEIM GMBH