FI875438A - Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. - Google Patents

Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. Download PDF

Info

Publication number: FI875438A
Authority: FI; Finland
Prior art keywords: pyrrolobenzimidazoler; nya; foerfarande foer; foer framstaellning; framstaellning
Prior art date: 1986-12-11

Application number

FI875438A

Other languages

English (en)

Other versions

FI875438A0 (fi

Inventor

Walter-Gunar Friebe

Alfred Mertens

Klaus Strein

Erwin Boehm

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-11

Filing date

1987-12-10

Publication date

1988-06-12

1987-12-10 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1987-12-10 Publication of FI875438A0 publication Critical patent/FI875438A0/fi

1988-06-12 Publication of FI875438A publication Critical patent/FI875438A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

FI875438A 1986-12-11 1987-12-10 Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. FI875438A (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19863642315 DE3642315A1 (de)	1986-12-11	1986-12-11	Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel

Publications (2)

Publication Number	Publication Date
FI875438A0 FI875438A0 (fi)	1987-12-10
FI875438A true FI875438A (fi)	1988-06-12

Family

ID=6315954

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI875438A FI875438A (fi)	1986-12-11	1987-12-10	Foerfarande foer framstaellning av nya pyrrolobenzimidazoler.

Country Status (13)

Country	Link
US (1)	US4863945A (fi)
EP (1)	EP0271040A3 (fi)
JP (1)	JPS63162692A (fi)
KR (1)	KR880007536A (fi)
AU (1)	AU8245087A (fi)
DD (1)	DD267047A5 (fi)
DE (1)	DE3642315A1 (fi)
DK (1)	DK650187A (fi)
FI (1)	FI875438A (fi)
HU (1)	HU200339B (fi)
IL (1)	IL84589A0 (fi)
PT (1)	PT86331B (fi)
ZA (1)	ZA879166B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5206240A (en) *	1989-12-08	1993-04-27	Merck & Co., Inc.	Nitrogen-containing spirocycles
DE4027592A1 (de) *	1990-08-31	1992-03-05	Beiersdorf Ag	Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5434163A (en) *	1993-05-14	1995-07-18	The Medical College Of Pennsylvania	Treatment of Cryptococcus neoformans infection
US6184226B1 (en)	1998-08-28	2001-02-06	Scios Inc.	Quinazoline derivatives as inhibitors of P-38 α
US6878714B2 (en) *	2001-01-12	2005-04-12	Amgen Inc.	Substituted alkylamine derivatives and methods of use
US6995162B2 (en)	2001-01-12	2006-02-07	Amgen Inc.	Substituted alkylamine derivatives and methods of use
EP1598353A1 (en) *	2004-05-17	2005-11-23	Boehringer Ingelheim International GmbH	Pyrrolobenzimidazolones and their use as antiproliferative agents
US7285569B2 (en)	2004-09-24	2007-10-23	Hoff Hoffmann-La Roche Inc.	Tricycles, their manufacture and use as pharmaceutical agents
US20060142247A1 (en) *	2004-12-17	2006-06-29	Guy Georges	Tricyclic heterocycles
WO2006108488A1 (en) *	2005-04-14	2006-10-19	F. Hoffmann-La Roche Ag	Tricyclic azole derivatives, their manufacture and use as pharmaceutical agents
AU2006233537A1 (en) *	2005-04-14	2006-10-19	F. Hoffmann-La Roche Ag	Aminopyrazole derivatives, their manufacture and use as pharmaceutical agents
CN101321762A (zh) *	2005-12-15	2008-12-10	霍夫曼-拉罗奇有限公司	三环内酰胺衍生物、它们的制备和作为药剂的应用
WO2007107346A1 (en) *	2006-03-23	2007-09-27	F. Hoffmann-La Roche Ag	Substituted indazole derivatives, their manufacture and use as pharmaceutical agents
WO2008063888A2 (en)	2006-11-22	2008-05-29	Plexxikon, Inc.	Compounds modulating c-fms and/or c-kit activity and uses therefor
EP2170830B1 (en)	2007-07-17	2014-10-15	Plexxikon, Inc.	2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS
US9447089B2 (en)	2009-04-03	2016-09-20	Plexxikon Inc.	Compositions and uses thereof
US8329724B2 (en)	2009-08-03	2012-12-11	Hoffmann-La Roche Inc.	Process for the manufacture of pharmaceutically active compounds
EA201290210A1 (ru)	2009-11-06	2012-10-30	Плексксикон, Инк.	Соединения и способы модуляции киназы и показания для их применения
EA028821B9 (ru)	2011-02-07	2018-10-31	Плексксикон, Инк.	Соединения и способы для модуляции киназ, а также показания к их применению
AR085279A1 (es)	2011-02-21	2013-09-18	Plexxikon Inc	Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9150570B2 (en)	2012-05-31	2015-10-06	Plexxikon Inc.	Synthesis of heterocyclic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL144822B1 (en) *	1984-05-12	1988-07-30	Boehringer Mannheim Gmbh	Method of obtaining novel pyrolobenzimidazoles
DE3445669A1 (de) *	1984-12-14	1986-06-19	Boehringer Mannheim Gmbh, 6800 Mannheim	Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3501497A1 (de) *	1985-01-18	1986-07-24	Boehringer Mannheim Gmbh, 6800 Mannheim	Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3531678A1 (de) *	1985-09-05	1987-03-12	Boehringer Mannheim Gmbh	Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

1986
- 1986-12-11 DE DE19863642315 patent/DE3642315A1/de not_active Withdrawn
1987
- 1987-11-25 IL IL84589A patent/IL84589A0/xx unknown
- 1987-12-07 ZA ZA879166A patent/ZA879166B/xx unknown
- 1987-12-07 EP EP87118046A patent/EP0271040A3/de not_active Withdrawn
- 1987-12-07 DD DD87310045A patent/DD267047A5/de not_active IP Right Cessation
- 1987-12-09 JP JP62309792A patent/JPS63162692A/ja active Pending
- 1987-12-10 PT PT86331A patent/PT86331B/pt not_active IP Right Cessation
- 1987-12-10 FI FI875438A patent/FI875438A/fi not_active Application Discontinuation
- 1987-12-10 US US07/131,367 patent/US4863945A/en not_active Expired - Fee Related
- 1987-12-10 HU HU875579A patent/HU200339B/hu not_active IP Right Cessation
- 1987-12-10 DK DK650187A patent/DK650187A/da not_active Application Discontinuation
- 1987-12-11 AU AU82450/87A patent/AU8245087A/en not_active Abandoned
- 1987-12-11 KR KR870014131A patent/KR880007536A/ko not_active Application Discontinuation

Also Published As

Publication number	Publication date
HU200339B (en)	1990-05-28
ZA879166B (en)	1988-06-14
DE3642315A1 (de)	1988-06-23
US4863945A (en)	1989-09-05
FI875438A0 (fi)	1987-12-10
IL84589A0 (en)	1988-04-29
HUT47278A (en)	1989-02-28
DK650187D0 (da)	1987-12-10
JPS63162692A (ja)	1988-07-06
AU8245087A (en)	1988-06-16
KR880007536A (ko)	1988-08-27
DK650187A (da)	1988-06-12
PT86331A (de)	1988-01-01
EP0271040A2 (de)	1988-06-15
PT86331B (pt)	1990-11-07
EP0271040A3 (de)	1989-11-02
DD267047A5 (de)	1989-04-19

Publication	Publication Date	Title
FI872878A (fi)	1987-12-31	Foerfarande foer framstaellning av nya algininsyraestrar.
FI874287A (fi)	1988-04-04	Nya lymfokinpeptider.
FI873704A (fi)	1988-02-29	Nya ksantinderivat.
FI870871A (fi)	1987-08-29	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara peptidderivat.
FI871406A (fi)	1987-10-02	Foerfarande foer framstaellning av nya aminosyraderivat.
FI875438A (fi)	1988-06-12	Foerfarande foer framstaellning av nya pyrrolobenzimidazoler.
FI873920A (fi)	1988-03-13	Foereskriftsstruktur foer infoering av nya element i kretsstruktur-syntesproceduren.
FI873193A (fi)	1988-01-24	Nya 18-fenylestranderivat.
FI873593A (fi)	1988-02-22	Nya applikationsformer foer -interferon.
FI883257A0 (fi)	1988-07-07	Nya peptider.
FI872571A (fi)	1987-12-13	Nya antracykliner.
FI872489A0 (fi)	1987-06-03	Foerfarande foer framstaellning av nya aralkylimidazolderivat.
FI875766A0 (fi)	1987-12-30	Foerfarande foer framstaellning av nya pyrimidinderivat.
FI893155A0 (fi)	1989-06-28	Nya foereningar.
FI871094A (fi)	1987-09-13	Nya monocykliska estrar.
FI870626A0 (fi)	1987-02-13	Nya polymerbarriaerblandningar.
FI872735A (fi)	1987-12-21	Nya vacciner.
FI872527A0 (fi)	1987-06-05	Foerfarande foer framstaellning av nya peptider.
FI875130A0 (fi)	1987-11-19	Nya benzokinoliner.
FI874885A0 (fi)	1987-11-04	Foerfarande foer framstaellning av nya kondenserade cykliska triazolderivat.
FI870091A0 (fi)	1987-01-12	Nya biocider.
FI861685A (fi)	1987-10-23	Foerfarande foer framstaellning av nya morfinanhydrazonderivat.
FI860837A (fi)	1987-08-28	Nya alfa-aminoalkyl-alfa-alkylfenylacetonitriler.
FI870872A0 (fi)	1987-02-27	Nya foereningar.
FI884633A (fi)	1988-10-07	Nya malonsyraderivatfoereningar.

Legal Events

Date	Code	Title	Description
2004-08-31	FD	Application lapsed	Owner name: BOEHRINGER MANNHEIM GMBH