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FI870448A0 - Antihistaminkompositioner, som innehaoller n-heterocyklyl-4-piperidinaminer. - Google Patents

Antihistaminkompositioner, som innehaoller n-heterocyklyl-4-piperidinaminer.

Info

Publication number
FI870448A0
FI870448A0 FI870448A FI870448A FI870448A0 FI 870448 A0 FI870448 A0 FI 870448A0 FI 870448 A FI870448 A FI 870448A FI 870448 A FI870448 A FI 870448A FI 870448 A0 FI870448 A0 FI 870448A0
Authority
FI
Finland
Prior art keywords
alkyl
substd
alkoxy
furanyl
opt
Prior art date
Application number
FI870448A
Other languages
English (en)
Other versions
FI870448A (fi
Inventor
Frans Eduard Janssens
Jozef Francis Hens
Joseph Leo Ghislanus Torremans
Jozef Jan Pieter Heykants
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI870448A0 publication Critical patent/FI870448A0/fi
Publication of FI870448A publication Critical patent/FI870448A/fi
Priority to FI904082A priority Critical patent/FI904082A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI870448A 1986-02-03 1987-02-02 Antihistaminkompositioner, som innehaoller n-heterocyklyl-4-piperidinaminer. FI870448A (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI904082A FI904082A0 (fi) 1986-02-03 1990-08-17 Foerfarande foer framstaellning av n-heterocyklyl-4-piperidinaminer.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82549186A 1986-02-03 1986-02-03

Publications (2)

Publication Number Publication Date
FI870448A0 true FI870448A0 (fi) 1987-02-02
FI870448A FI870448A (fi) 1987-08-04

Family

ID=25244134

Family Applications (1)

Application Number Title Priority Date Filing Date
FI870448A FI870448A (fi) 1986-02-03 1987-02-02 Antihistaminkompositioner, som innehaoller n-heterocyklyl-4-piperidinaminer.

Country Status (26)

Country Link
EP (1) EP0232937B1 (fi)
JP (2) JPH0794393B2 (fi)
CN (1) CN1018614B (fi)
AT (1) ATE79620T1 (fi)
AU (1) AU583706B2 (fi)
CA (1) CA1327579C (fi)
CY (1) CY1865A (fi)
DE (1) DE3781173T2 (fi)
DK (1) DK173674B1 (fi)
EG (1) EG17993A (fi)
ES (1) ES2052544T3 (fi)
FI (1) FI870448A (fi)
GR (1) GR3006158T3 (fi)
HK (1) HK114695A (fi)
HU (1) HU201067B (fi)
IE (1) IE60885B1 (fi)
IL (1) IL81448A (fi)
MA (1) MA20868A1 (fi)
NO (1) NO870407L (fi)
NZ (1) NZ219165A (fi)
PH (1) PH24738A (fi)
PT (1) PT84234B (fi)
TN (1) TNSN87015A1 (fi)
ZA (1) ZA87744B (fi)
ZM (1) ZM1287A1 (fi)
ZW (1) ZW2087A1 (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ223654A (en) * 1987-03-09 1990-03-27 Janssen Pharmaceutica Nv 1-alkyl-substituted-benzimidazole-4-piperidinamines and pharmaceutical compositions
US4897401A (en) * 1987-06-19 1990-01-30 Janssen Pharmaceutical N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases
CA1317939C (en) * 1987-07-01 1993-05-18 Janssen Pharmaceutica Naamloze Vennootschap ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines
US4988689A (en) * 1987-07-01 1991-01-29 Janssen Pharmaceutica N.V. ((Pharmacologically active bicyclic heterocyclic)methyl and -heteroatom) substituted hexahydro-1H-azepines and pyrrolidines
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
IT1229231B (it) * 1989-05-08 1991-07-26 Dompe Farmaceutici Spa Aminoimidazopiridine farmacologicamente attive
CA2043564A1 (en) * 1990-07-06 1992-01-07 Alfons G. M. De Knaep 3-[(5-methyl-2-furanyl)methyl]-n-(4-piperidinyl)-3h-imidazo [4,5-b]-pyridin-2-amine 2-hydroxy-1,2,3-propanetricarboxylate
NZ239540A (en) * 1990-09-24 1993-11-25 Neurosearch As 1-phenyl benzimidazole derivatives and medicaments
DK0658110T3 (da) * 1992-09-03 2000-04-17 Sepracor Inc Anvendelse af norastemizol til behandling af allergisk rhinitis
AU730229B2 (en) * 1992-09-03 2001-03-01 Sepracor, Inc. Use of norastemizole for the treatment of allergic disorders
US5624948A (en) * 1993-05-20 1997-04-29 Kissei Pharmaceutical Co., Ltd. 1-(2-benzimidazolyl)-1,5-diazacyclooctane compounds
TW429256B (en) * 1995-12-27 2001-04-11 Janssen Pharmaceutica Nv 1-(1,2-disubstituted piperidinyl)-4-(benzimidazolyl- and imidazopyridinyl)-piperidine derivatives
CA2284705A1 (en) * 1997-03-26 1998-10-01 Sepracor Inc. Chemically and thermally stable norastemizole formulations
US5817823A (en) * 1997-04-17 1998-10-06 Sepracor Inc. Method for synthesizing 2-substituted imidazoles
SK18952001A3 (sk) * 1999-06-28 2002-11-06 Janssen Pharmaceutica N. V. Inhibítory replikácie respiračného syncyciálneho vírusu
PT1196409E (pt) 1999-06-28 2004-06-30 Janssen Pharmaceutica Nv Inibidores da replicacao do virus sincicial respiratorio
MXPA02000112A (es) * 1999-06-28 2002-07-02 Janssen Pharmaceutica Nv Inhibidores de la replicacion del virus sincitial respiratorio.
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
WO2004113297A2 (en) * 2003-06-24 2004-12-29 Neurosearch A/S Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US20050222198A1 (en) 2003-12-22 2005-10-06 K.U. Leuven Research & Development, Gerhard Puerstinger And Gilead Sciences, Inc. Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment
DE602005013580D1 (de) 2004-12-21 2009-05-07 Leuven K U Res & Dev Imidazoä4,5-cüpyridinverbindung und verfahren zur antiviralen behandlung
WO2006067532A1 (en) 2004-12-24 2006-06-29 Prosidion Ltd G-protein coupled receptor agonists
AU2006221984C1 (en) 2005-03-08 2012-02-09 Janssen Pharmaceutica N.V. Diaza-spiro-[4.4]-nonane derivatives as neurokinin (NK1) antagonists
AU2007269614B2 (en) 2006-07-07 2011-09-08 Gilead Sciences, Inc. Novel pyridazine compound and use thereof
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
JP5764064B2 (ja) * 2008-09-26 2015-08-12 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 抗糖尿病薬として有用な新規な環状ベンゾイミダゾール誘導体

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4219559A (en) * 1979-01-10 1980-08-26 Janssen Pharmaceutica N.V. N-Heterocyclyl-4-piperidinamines
CA1140119A (en) * 1978-04-03 1983-01-25 Joseph Torremans N-heterocyclyl-4-piperidinamines
US4556660A (en) * 1982-07-12 1985-12-03 Janssen Pharmaceutica N.V. N-(Bicyclic heterocyclyl)-4-piperidinamines
IN156065B (fi) * 1982-07-12 1985-05-04 Janssen Pharmaceutica Nv
US4634704A (en) * 1983-10-06 1987-01-06 Janssen Pharmaceutica, N.V. Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines
EP0144101B1 (en) * 1983-11-30 1991-02-06 Janssen Pharmaceutica N.V. Bicyclic heterocyclyl containing n-(bicyclic heterocyclyl)-4-piperidinamines
JPS60174778A (ja) * 1984-01-09 1985-09-09 ジヤンセン・フア−マシユ−チカ・ナ−ムロ−ゼ・フエンノ−トシヤツプ Ｎ−ヘテロシクリル−４−ピペリジンアミン
US4588722A (en) * 1984-01-09 1986-05-13 Janssen Pharmaceutica N.V. N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives
PH23995A (en) * 1984-01-09 1990-02-09 Janssen Pharmaceutica Nv 4((bicycle heterocyclyl)-methyl and hetero)piperidines

Also Published As

Publication number Publication date
AU583706B2 (en) 1989-05-04
IL81448A0 (en) 1987-09-16
HUT44544A (en) 1988-03-28
CN1018614B (zh) 1992-10-14
DK173674B1 (da) 2001-06-05
JPH07179458A (ja) 1995-07-18
JPH0794393B2 (ja) 1995-10-11
GR3006158T3 (fi) 1993-06-21
CY1865A (en) 1996-04-05
ZM1287A1 (en) 1988-08-29
ZW2087A1 (en) 1988-08-31
DE3781173T2 (de) 1992-12-17
CA1327579C (en) 1994-03-08
EG17993A (en) 1991-08-30
IE870258L (en) 1987-08-03
ZA87744B (en) 1988-10-26
ATE79620T1 (de) 1992-09-15
DK54187D0 (da) 1987-02-02
DK54187A (da) 1987-08-04
EP0232937B1 (en) 1992-08-19
PT84234B (pt) 1989-09-14
AU6821887A (en) 1987-08-06
NO870407D0 (no) 1987-02-02
HU201067B (en) 1990-09-28
EP0232937A3 (en) 1988-04-06
JPS62215575A (ja) 1987-09-22
DE3781173D1 (de) 1992-09-24
MA20868A1 (fr) 1987-10-01
FI870448A (fi) 1987-08-04
JPH0819126B2 (ja) 1996-02-28
NZ219165A (en) 1990-04-26
IL81448A (en) 1990-09-17
NO870407L (no) 1987-08-04
PH24738A (en) 1990-10-01
EP0232937A2 (en) 1987-08-19
HK114695A (en) 1995-07-21
TNSN87015A1 (fr) 1990-01-01
IE60885B1 (en) 1994-08-24
ES2052544T3 (es) 1994-07-16
CN87100563A (zh) 1987-08-19
PT84234A (en) 1987-03-01

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Legal Events

Date Code Title Description
FA Application withdrawn

Owner name: JANSSEN PHARMACEUTICA N.V.