FI86428C - Foerfarande foer framstaellning av terapeutiskt aktiva 10-substituerad-9-fluor-7-oxo-2,3-dihydro-7h-pyrido -/3,2,1-ij/-1,3,4-bensoxadiazin-6-karboxylsyraderivat. - Google Patents

Foerfarande foer framstaellning av terapeutiskt aktiva 10-substituerad-9-fluor-7-oxo-2,3-dihydro-7h-pyrido -/3,2,1-ij/-1,3,4-bensoxadiazin-6-karboxylsyraderivat. Download PDF

Info

Publication number: FI86428C
Authority: FI; Finland
Prior art keywords: oxo; compound; methyl; dihydro; pyrido
Prior art date: 1986-09-12

Application number

FI873940A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI873940A (fi

FI86428B (fi

FI873940A0 (fi

Inventor

Masahiro Aoki

Miyako Kamata

Tatsuo Ohtsuka

Nobuo Shimma

Kazuteru Yokose

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-12

Filing date

1987-09-11

Publication date

1992-08-25

1987-09-11 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1987-09-11 Publication of FI873940A0 publication Critical patent/FI873940A0/fi

1988-03-13 Publication of FI873940A publication Critical patent/FI873940A/fi

1990-08-30 Priority to FI904278A priority Critical patent/FI93357C/fi

1990-08-30 Priority to FI904279A priority patent/FI88041C/fi

1992-05-15 Publication of FI86428B publication Critical patent/FI86428B/fi

1992-08-25 Application granted granted Critical

1992-08-25 Publication of FI86428C publication Critical patent/FI86428C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Quinoline Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI873940A 1986-09-12 1987-09-11 Foerfarande foer framstaellning av terapeutiskt aktiva 10-substituerad-9-fluor-7-oxo-2,3-dihydro-7h-pyrido -/3,2,1-ij/-1,3,4-bensoxadiazin-6-karboxylsyraderivat. FI86428C (fi)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
FI904278A FI93357C (fi)	1986-09-12	1990-08-30	8-hydroksi-1-amino-4-okso-1,4-dihydro-3-kinoliinijohdannaisia
FI904279A FI88041C (fi)	1986-09-12	1990-08-30	Pyrido/3,2,1-ij/-1,3,4-bensoxadiazin-6-karboxylsyraderivat

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP86112619		1986-09-12
EP86112619		1986-09-12

Publications (4)

Publication Number	Publication Date
FI873940A0 FI873940A0 (fi)	1987-09-11
FI873940A FI873940A (fi)	1988-03-13
FI86428B FI86428B (fi)	1992-05-15
FI86428C true FI86428C (fi)	1992-08-25

Family

ID=8195410

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI873940A FI86428C (fi)	1986-09-12	1987-09-11	Foerfarande foer framstaellning av terapeutiskt aktiva 10-substituerad-9-fluor-7-oxo-2,3-dihydro-7h-pyrido -/3,2,1-ij/-1,3,4-bensoxadiazin-6-karboxylsyraderivat.

Country Status (22)

Country	Link
JP (3)	JPH0696578B2 (no)
KR (1)	KR960002857B1 (no)
CN (1)	CN1017800B (no)
AT (1)	AT389119B (no)
AU (1)	AU602534B2 (no)
CA (1)	CA1336905C (no)
CZ (1)	CZ281195B6 (no)
DK (1)	DK173330B1 (no)
DZ (1)	DZ1124A1 (no)
FI (1)	FI86428C (no)
HU (1)	HU199481B (no)
IE (1)	IE61624B1 (no)
IL (1)	IL83814A (no)
MC (1)	MC1850A1 (no)
MX (1)	MX8302A (no)
NO (1)	NO169125C (no)
NZ (1)	NZ221681A (no)
PH (1)	PH23930A (no)
PT (1)	PT85686B (no)
SK (1)	SK278990B6 (no)
ZA (1)	ZA876636B (no)
ZW (1)	ZW16387A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZW16387A1 (en) *	1986-09-12	1988-05-25	Hoffmann La Roche	Tricyclic compounds
EP1757598A4 (en)	2004-05-13	2010-07-21	Daiichi Seiyaku Co	SUBSTITUTED PYRROLIDINE DERIVATIVE
US7563805B2 (en) *	2005-05-19	2009-07-21	Daiichi Pharmaceutical Co., Ltd.	Tri-, tetra-substituted-3-aminopyrrolidine derivative
DK2383271T3 (da)	2006-03-13	2013-10-07	Kyorin Seiyaku Kk	Aminoquinoloner som GSK-3-inhibitorer
KR101563018B1 (ko)	2007-09-11	2015-10-23	교린 세이야꾸 가부시키 가이샤	Ｇｓｋ-３ 억제제로서의 시아노아미노퀴놀론 및 테트라졸로아미노퀴놀론
CN102344457B (zh)	2007-09-12	2015-07-22	杏林制药株式会社	作为 gsk-3 抑制剂的螺环状氨基喹诺酮
FR2928150A1 (fr) *	2008-02-29	2009-09-04	Vetoquinol Sa Sa	Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
EP2145891A1 (en) *	2008-07-09	2010-01-20	Vetoquinol S.A.	9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
KR101748891B1 (ko)	2009-03-11	2017-06-19	교린 세이야꾸 가부시키 가이샤	Ｇｓｋ-3 억제제로서의 7-시클로알킬아미노퀴놀론
CN107522718B (zh) *	2017-09-14	2019-11-08	浙江国邦药业有限公司	一种马波沙星的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZW16387A1 (en) *	1986-09-12	1988-05-25	Hoffmann La Roche	Tricyclic compounds

1987
- 1987-08-28 ZW ZW163/87A patent/ZW16387A1/xx unknown
- 1987-09-04 NZ NZ221681A patent/NZ221681A/en unknown
- 1987-09-04 ZA ZA876636A patent/ZA876636B/xx unknown
- 1987-09-07 AU AU78114/87A patent/AU602534B2/en not_active Expired
- 1987-09-07 IL IL83814A patent/IL83814A/xx not_active IP Right Cessation
- 1987-09-09 DZ DZ870149A patent/DZ1124A1/fr active
- 1987-09-09 HU HU874007A patent/HU199481B/hu unknown
- 1987-09-10 MC MC871911A patent/MC1850A1/xx unknown
- 1987-09-11 PT PT85686A patent/PT85686B/pt unknown
- 1987-09-11 CZ CS876604A patent/CZ281195B6/cs not_active IP Right Cessation
- 1987-09-11 KR KR1019870010082A patent/KR960002857B1/ko not_active IP Right Cessation
- 1987-09-11 SK SK6604-87A patent/SK278990B6/sk unknown
- 1987-09-11 NO NO873816A patent/NO169125C/no unknown
- 1987-09-11 CA CA000546674A patent/CA1336905C/en not_active Expired - Lifetime
- 1987-09-11 PH PH35800A patent/PH23930A/en unknown
- 1987-09-11 FI FI873940A patent/FI86428C/fi not_active IP Right Cessation
- 1987-09-11 DK DK198704772A patent/DK173330B1/da not_active IP Right Cessation
- 1987-09-11 IE IE244487A patent/IE61624B1/en not_active IP Right Cessation
- 1987-09-12 JP JP62227579A patent/JPH0696578B2/ja not_active Expired - Fee Related
- 1987-09-12 CN CN87106838A patent/CN1017800B/zh not_active Expired
- 1987-09-14 MX MX830287A patent/MX8302A/es unknown
- 1987-10-08 AT AT0263887A patent/AT389119B/de not_active IP Right Cessation
1994
- 1994-05-25 JP JP6133894A patent/JPH0826030B2/ja not_active Expired - Lifetime
- 1994-05-25 JP JP6133905A patent/JPH0819120B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPH0826030B2 (ja)	1996-03-13
CN1017800B (zh)	1992-08-12
NO873816D0 (no)	1987-09-11
DK477287D0 (da)	1987-09-11
FI873940A (fi)	1988-03-13
JPH0819120B2 (ja)	1996-02-28
FI86428B (fi)	1992-05-15
NZ221681A (en)	1990-12-21
NO169125C (no)	1992-05-13
SK660487A3 (en)	1998-05-06
HU199481B (en)	1990-02-28
JPH07138262A (ja)	1995-05-30
IE872444L (en)	1988-03-12
JPS63132891A (ja)	1988-06-04
JPH0696578B2 (ja)	1994-11-30
AU602534B2 (en)	1990-10-18
CZ281195B6 (cs)	1996-07-17
KR880003954A (ko)	1988-06-01
PH23930A (en)	1990-01-23
CN87106838A (zh)	1988-05-11
ZW16387A1 (en)	1988-05-25
DK477287A (da)	1988-03-13
NO169125B (no)	1992-02-03
AT389119B (de)	1989-10-25
SK278990B6 (sk)	1998-05-06
ZA876636B (en)	1988-07-27
MX8302A (es)	1993-12-01
IL83814A (en)	1991-09-16
CA1336905C (en)	1995-09-05
ATA263887A (de)	1989-03-15
HUT47294A (en)	1989-02-28
CZ660487A3 (en)	1996-04-17
DZ1124A1 (fr)	2004-09-13
MC1850A1 (fr)	1988-09-30
IE61624B1 (en)	1994-11-16
AU7811487A (en)	1988-03-17
NO873816L (no)	1988-03-14
KR960002857B1 (ko)	1996-02-27
PT85686B (pt)	1990-05-31
PT85686A (en)	1987-10-01
DK173330B1 (da)	2000-07-24
FI873940A0 (fi)	1987-09-11
JPH07138256A (ja)	1995-05-30

Publication	Publication Date	Title
US5312823A (en)	1994-05-17	7-azaisoindolinyl-quinolone-carboxylic acid derivatives
EP0237955B1 (en)	1992-07-15	Quinolonecarboxylic acid derivatives and their preparation
CN102341394B (zh)	2015-04-15	聚(adp-核糖)聚合酶(parp)抑制剂
US4801584A (en)	1989-01-31	Pyrido(3,2,1-IJ)-1,3,4 benzoxadiazine derivatives
IE81144B1 (en)	2000-05-03	7-(1-Pyrrolidinyl)-3-quinolone-and -naphthyridone-carboxylic acid derivatives processes for their preparation and substituted mono- and bicyclic pyrrolidine derivatives as intermediate products for their preparation and antibacterial agents and feed additives containing them
US4843070A (en)	1989-06-27	Substituted thiazetoquinoline-3-carboxylic acids and pharmaceutically acceptable salts thereof
HU179927B (en)	1983-01-28	Process for preparing naphthyridine derivatives
FI86428C (fi)	1992-08-25	Foerfarande foer framstaellning av terapeutiskt aktiva 10-substituerad-9-fluor-7-oxo-2,3-dihydro-7h-pyrido -/3,2,1-ij/-1,3,4-bensoxadiazin-6-karboxylsyraderivat.
GB2158825A (en)	1985-11-20	Naphthyridines
DK165635B (da)	1992-12-28	1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-1,8-naphthyridin-3-carboxy-derivater, farmaceutisk praeparat omfattende saadanne forbindelser, samt fremgangsmaade til fremstilling af forbindelserne
IE65732B1 (en)	1995-11-15	Heterocylic-substituted quinoline-carboxylic acids
US4864023A (en)	1989-09-05	Pyrido(3,2,1-IJ)-1,3,4-benzoxadiazine derivatives
KR940006595B1 (ko)	1994-07-23	피리돈카르복실산의 아제티딘 유도체, 그의 제조방법 및 이를 함유하는 의약품조성물
CZ280594A3 (en)	1995-08-16	Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid, process of their preparation and use in medicaments
FI88041B (fi)	1992-12-15	Pyrido/3,2,1-ij/-1,3,4-bensoxadiazin-6-karboxylsyraderivat
JPH08253480A (ja)	1996-10-01	１，６−ナフチリドンカルボン酸誘導体
NO171162B (no)	1992-10-26	Pyrido-benzoksadiazinderivater

Legal Events

Date	Code	Title	Description
2004-08-31	FG	Patent granted	Owner name: F. HOFFMANN-LA ROCHE AG
2007-09-30	MA	Patent expired