FI860018A - Laekemedelspreparat med reducerad toxisitet. - Google Patents

Laekemedelspreparat med reducerad toxisitet.

Info

Publication number: FI860018A
Authority: FI; Finland
Prior art keywords: toxisitet; reducerad; leekemedelspreparat; med; drug
Prior art date: 1984-05-02

Application number

FI860018A

Other languages

English (en)

Other versions

FI860018A0 (fi

Inventor

Andrew Stuart Janoff

Mircea Constantine Popescu

Carl R Alving

Original Assignee

Liposome Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-05-02

Filing date

1986-01-02

Publication date

1986-01-02

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24419861&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI860018(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-01-02 Application filed by Liposome Co Inc filed Critical Liposome Co Inc

1986-01-02 Publication of FI860018A0 publication Critical patent/FI860018A0/fi

1986-01-02 Publication of FI860018A publication Critical patent/FI860018A/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
- A61K47/544—Phospholipids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Dispersion Chemistry (AREA)
Toxicology (AREA)
Biophysics (AREA)
Botany (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

FI860018A 1984-05-02 1986-01-02 Laekemedelspreparat med reducerad toxisitet. FI860018A (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US60450384A	1984-05-02	1984-05-02
PCT/US1984/000855 WO1985005030A1 (en)	1984-05-02	1984-05-31	Drug preparations of reduced toxicity

Publications (2)

Publication Number	Publication Date
FI860018A0 FI860018A0 (fi)	1986-01-02
FI860018A true FI860018A (fi)	1986-01-02

Family

ID=24419861

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI860018A FI860018A (fi)	1984-05-02	1986-01-02	Laekemedelspreparat med reducerad toxisitet.

Country Status (11)

Country	Link
EP (1)	EP0180581B2 (fi)
JP (1)	JP2506323B2 (fi)
AT (1)	ATE65912T1 (fi)
AU (1)	AU3063884A (fi)
DE (1)	DE3484904D1 (fi)
DK (1)	DK607885D0 (fi)
FI (1)	FI860018A (fi)
HK (1)	HK32492A (fi)
PT (1)	PT78628B (fi)
SG (1)	SG18792G (fi)
WO (1)	WO1985005030A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5409704A (en) *	1985-06-26	1995-04-25	The Liposome Company, Inc.	Liposomes comprising aminoglycoside phosphates and methods of production and use
US5043107A (en) *	1986-08-21	1991-08-27	Vestar Research, Inc.	Preparation small unilamellar vesicles including polyene antifungal antibiotics
IE60901B1 (en) *	1986-08-21	1994-08-24	Vestar Inc	Improved treatment of systemic fungal infections with phospholipid particles encapsulating polyene antifungal antibiotics
US4822777A (en) *	1987-02-27	1989-04-18	Liposome Technology, Inc.	Amphotericin B/cholesterol sulfate composition
US5616334A (en) *	1987-03-05	1997-04-01	The Liposome Company, Inc.	Low toxicity drug-lipid systems
US6406713B1 (en)	1987-03-05	2002-06-18	The Liposome Company, Inc.	Methods of preparing low-toxicity drug-lipid complexes
AU598958B2 (en)	1987-11-12	1990-07-05	Vestar, Inc.	Improved amphotericin b liposome preparation
US4946683A (en) *	1987-11-18	1990-08-07	Vestar, Inc.	Multiple step entrapment/loading procedure for preparing lipophilic drug-containing liposomes
CA2044663A1 (en) *	1990-07-12	1992-01-13	Makoto Tanaka	Water-dispersible polyene antifungal complexes
PT100486B (pt) *	1992-05-14	1999-07-30	Ineti Inst Nac Engenh E Tecnol	Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao
JP2915296B2 (ja) *	1993-08-30	1999-07-05	宇野潤	抗真菌製剤
IL136342A0 (en) *	1997-12-01	2001-05-20	Yissum Res Dev Co	Formulation for topical treatment of skin infections
WO2003002096A1 (en)	2001-06-28	2003-01-09	Wisconsin Alumni Research Foundation	Methods and compositions for polyene antibiotics with reduced toxicity
CN104856931B (zh) *	2014-02-24	2019-06-18	石药集团中奇制药技术（石家庄）有限公司	一种两性霉素b纳米复合物及其制备方法
CN116473985B (zh) *	2023-03-29	2024-12-10	暨南大学	一种多烯类抗真菌药物组合物及其应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TR19072A (tr) *	1973-11-26	1978-05-01	Pepro	Fosforlu tuerevler ihtiva eden fungisid terkipler
US4119724A (en) *	1973-11-26	1978-10-10	Pepro	Fungicidal compositions containing phosphorous acid and derivatives thereof
US3993754A (en) *	1974-10-09	1976-11-23	The United States Of America As Represented By The United States Energy Research And Development Administration	Liposome-encapsulated actinomycin for cancer chemotherapy
US4160827A (en) *	1978-02-06	1979-07-10	The Upjohn Company	Metronidazole phosphate and salts
US4263428A (en) *	1978-03-24	1981-04-21	The Regents Of The University Of California	Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
IL55431A (en) *	1978-08-24	1982-07-30	Yeda Res & Dev	Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
DE2856333C2 (de) *	1978-12-27	1983-09-22	A. Nattermann & Cie GmbH, 5000 Köln	Oral einnehmbare Arzneimittel mit entzündungshemmender Wirkung
US4272525A (en) *	1978-10-23	1981-06-09	Schering Corporation	Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
GR73668B (fi) *	1978-11-21	1984-03-28	Hoffmann La Roche
GB2046092B (en) *	1979-03-05	1983-11-02	Toyama Chemical Co Ltd	Pharmaceutical composition containing a lysophospholid and a phospholipid
US4291023A (en) *	1979-03-07	1981-09-22	Engelhard Minerals & Chemicals Corp.	Method for treating tumors using cis-diammineplatinum (II) organophosphate complexes
US4287187A (en) *	1979-03-07	1981-09-01	Engelhard Minerals & Chemicals Corporation	Method for treating tumors with cis-diammineplatinum(II) orthophosphate complexes
US4291027A (en) *	1979-03-07	1981-09-22	Engelhard Minerals & Chemicals Corp.	Method for treating tumors with ethylenediamine platinum (II) and 1,2-diaminocyclohexane-platinum (II) pyrophosphate complexes
DE2914789A1 (de) *	1979-04-11	1980-10-16	Nattermann A & Cie	Injizierbare arzneimittel mit entzuendungshemmender wirkung
CA1173360A (en) *	1979-06-22	1984-08-28	Jurg Schrank	Pharmaceutical preparations
DE2941384A1 (de) *	1979-10-12	1981-04-23	Bayer Ag, 5090 Leverkusen	Phosphono-hydroxy-essigsaeure, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2952115C2 (de) *	1979-12-22	1982-05-06	A. Nattermann & Cie GmbH, 5000 Köln	Rosmarinsäure-Phospholipid-Komplex
HU184141B (en) *	1979-12-27	1984-07-30	Human Oltoanyagtermelo	Adjuvant particles compositions containing said particles and biologically active substances adsorbed thereon and a process for the preparation thereof
US4346084A (en) *	1980-02-29	1982-08-24	Massachusetts Institute Of Technology	Process and composition for treating disorders by administering lithium and choline
US4430330A (en) *	1980-02-29	1984-02-07	Massachusetts Institute Of Technology	Process and composition for treating disorders by administering a phenothiazine and choline
JPS5793909A (en) *	1980-12-03	1982-06-11	Sankyo Co Ltd	Carcinostatic pharmaceutical having directivity to specific internal organ and its preparation
US4419348A (en) *	1981-04-27	1983-12-06	Georgetown University	Anthracycline glycoside compositions, their use and preparation
US4397846A (en) *	1981-05-15	1983-08-09	Murray Weiner	Storage-stable lipid vesicles and method of preparation

1984
- 1984-05-22 PT PT78628A patent/PT78628B/pt unknown
- 1984-05-31 AT AT84902408T patent/ATE65912T1/de not_active IP Right Cessation
- 1984-05-31 WO PCT/US1984/000855 patent/WO1985005030A1/en active IP Right Grant
- 1984-05-31 DE DE8484902408T patent/DE3484904D1/de not_active Expired - Lifetime
- 1984-05-31 AU AU30638/84A patent/AU3063884A/en not_active Abandoned
- 1984-05-31 EP EP84902408A patent/EP0180581B2/en not_active Expired - Lifetime
- 1984-05-31 JP JP59502364A patent/JP2506323B2/ja not_active Expired - Lifetime
1985
- 1985-12-30 DK DK607885A patent/DK607885D0/da not_active Application Discontinuation
1986
- 1986-01-02 FI FI860018A patent/FI860018A/fi not_active Application Discontinuation
1992
- 1992-02-27 SG SG187/92A patent/SG18792G/en unknown
- 1992-04-30 HK HK324/92A patent/HK32492A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK607885A (da)	1985-12-30
EP0180581B2 (en)	1995-12-20
PT78628A (en)	1984-06-01
DK607885D0 (da)	1985-12-30
AU3063884A (en)	1985-11-28
EP0180581A1 (en)	1986-05-14
HK32492A (en)	1992-05-08
PT78628B (en)	1986-06-18
JPS61502055A (ja)	1986-09-18
JP2506323B2 (ja)	1996-06-12
ATE65912T1 (de)	1991-08-15
EP0180581B1 (en)	1991-08-07
FI860018A0 (fi)	1986-01-02
WO1985005030A1 (en)	1985-11-21
EP0180581A4 (en)	1988-04-27
DE3484904D1 (de)	1991-09-12
SG18792G (en)	1992-04-16

Publication	Publication Date	Title
ES8603272A1 (es)	1985-12-16	Procedimiento de producir un preparado de farmaco de toxicidad reducida
FI860018A (fi)	1986-01-02	Laekemedelspreparat med reducerad toxisitet.
FI875533A (fi)	1987-12-16	Insulinpreparat foer non-parenteral dosering.
IT8467767A1 (it)	1986-02-01	Preparati farmaceutici ad attività antimicrobica e procedimento per la loro preparazione.
DE3580616D1 (de)	1991-01-03	Mitomycinderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
ATE37028T1 (de)	1988-09-15	Cephalosporinverbindungen, ihre herstellung, pharmazeutische praeparate und eingangsprodukte.
NL191890C (nl)	1996-10-04	Oxochinolinederivaten met antimicrobiële werking, hun bereidingswijze en een antimicrobieel preparaat daaruit.
NL193981B (nl)	2000-12-01	7-(eventueel gesubstitueerd naftyl)-3-methyl-octa-2,4,6-trieenderivaten met retineachtige werking alsmede farmaceutische en kosmetische preparaten die dergelijke derivaten bevatten.
BR8702654A (pt)	1988-02-23	Sistema para administracao pulsatil de drogas
MX18786A (es)	1993-12-01	Complejos macrociclicos de acido aminofonico, su preparacion, formulaciones y empleo.
NL970029I2 (nl)	1998-04-01	Benzimidazoolderivaten, bereiding en therapeutische toepassing.
DE3684755D1 (de)	1992-05-14	Behandlung von tieren mit il-2, zubereitungen dafuer und ihre herstellung.
NO165071C (no)	1990-12-19	Analogifremgangsmaate for fremstilling av terapeutisk aktive 7-(3-amino-1-pyrrolidinyl)-8-klor-1-cyklopropyl-6- fluor-1,4,-dihydro-4-okso-3-kinolin-karboksylsyre.
DE3867086D1 (de)	1992-02-06	Benzothiepino(5,4-c)pyridazin-verbindungen und ihre pharmazeutischen wirkungen.
ATE32882T1 (de)	1988-03-15	Phenylnonatetraensaeurederivate, ihre herstellung und pharmazeutische praeparate mit diesen derivaten.
IT8423896A0 (it)	1984-12-05	Diacilderivati della glicerilfosforilcolina ad attivita' terapeutica, procedimento per laloro preparazione e relative composizioni farmaceutiche.
MX9202273A (es)	1993-05-01	Derivados de piridona aminoacido azetidinil substituidos, su preparacion y su aplicacion como medicamentos.
IT8722218A0 (it)	1987-10-12	Ftalazino derivati ad attivita'farmaceutica.
IL77009A0 (en)	1986-04-29	Biphenylyloxy and biphenylylalkoxy aryl acyl urea derivatives,processes for the preparation thereof and pesticidal compositions containing the same
DE3671630D1 (de)	1990-07-05	Glycero-3(2)-phospho-l-serinderivate und diese enthaltende pharmazeutischen praeparate.
DE3579074D1 (de)	1990-09-13	Verminderung der toxischen wirkungen von anthrachinon-medikamenten.
IT8520514A0 (it)	1985-04-26	Composizioni di farmaci dotate di attivita' antimicrobica eprocedimento per la loro preparazione.
ATE70840T1 (de)	1992-01-15	Benzothiepino(5,4-c>pyridazin-verbindungen und ihre pharmazeutischen wirkungen.
MX9203662A (es)	1992-07-01	Preparaciones de medicamento con toxicidad reducida.
IT8220271A0 (it)	1982-03-19	Derivati di eterociclici azotati dotati di attivita'fitoregolatrice.

Legal Events

Date	Code	Title	Description
2004-08-31	FA	Application withdrawn	Owner name: THE LIPOSOME COMPANY, INC.