FI850226A0 - Foerfarande foer framstaellning av leukotrienantagonister. - Google Patents

Foerfarande foer framstaellning av leukotrienantagonister.

Info

Publication number: FI850226A0
Authority: FI; Finland
Prior art keywords: leukotrienantagonister; foerfarande foer; foer framstaellning; framstaellning; foerfarande
Prior art date: 1984-01-19

Application number

FI850226A

Other languages

English (en)

Other versions

FI850226L (fi

FI79698C (fi

FI79698B (fi

Inventor

John Gerald Gleason

Carl David Perchonock

Original Assignee

Smithkline Beckman Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-01-19

Filing date

1985-01-17

Publication date

1985-01-17

1985-01-17 Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp

1985-01-17 Publication of FI850226A0 publication Critical patent/FI850226A0/fi

1985-07-20 Publication of FI850226L publication Critical patent/FI850226L/fi

1989-10-31 Application granted granted Critical

1989-10-31 Publication of FI79698B publication Critical patent/FI79698B/fi

1990-02-12 Publication of FI79698C publication Critical patent/FI79698C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/542—Alkylated benzaldehydes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/546—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings polycyclic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/548—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings having unsaturation outside the six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/86—Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI850226A 1984-01-19 1985-01-17 Foerfarande foer framstaellning av farmakologiskt aktiva ditiaalkandisyror. FI79698C (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US57202184A	1984-01-19	1984-01-19
US57202184		1984-01-19
US63050084A	1984-07-13	1984-07-13
US63050084		1984-07-13

Publications (4)

Publication Number	Publication Date
FI850226A0 true FI850226A0 (fi)	1985-01-17
FI850226L FI850226L (fi)	1985-07-20
FI79698B FI79698B (fi)	1989-10-31
FI79698C FI79698C (fi)	1990-02-12

Family

ID=27075709

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI850226A FI79698C (fi)	1984-01-19	1985-01-17	Foerfarande foer framstaellning av farmakologiskt aktiva ditiaalkandisyror.

Country Status (15)

Country	Link
EP (1)	EP0168902B1 (fi)
KR (1)	KR900000683B1 (fi)
AU (1)	AU571635B2 (fi)
CA (1)	CA1243035A (fi)
DE (1)	DE3560717D1 (fi)
DK (1)	DK21085A (fi)
ES (1)	ES8609230A1 (fi)
FI (1)	FI79698C (fi)
GR (1)	GR850106B (fi)
HU (1)	HU195638B (fi)
IL (1)	IL74068A (fi)
NO (1)	NO160576C (fi)
NZ (1)	NZ210839A (fi)
PT (1)	PT79835B (fi)
ZW (1)	ZW1085A1 (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3672130D1 (de) *	1985-04-19	1990-07-26	Smithkline Beecham Corp	Leukotrien-antagonisten.
US4871771A (en) *	1988-02-04	1989-10-03	Smithkline Beckman Corporation	Leukotriene antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE616326A (fi) *	1961-04-17	1900-01-01
FR2468362A1 (fr) *	1978-07-12	1981-05-08	Oreal	Compositions cosmetiques a base de dithioethers pour le traitement de l'etat gras des cheveux et de la peau, nouveaux composes et leur procede d'obtention
US4269731A (en) *	1979-08-27	1981-05-26	Argus Chemical Corporation	Antimony mercaptocarboxylic acid ester stabilizers for polyvinyl chloride resin compositions and process

1985
- 1985-01-14 CA CA000472021A patent/CA1243035A/en not_active Expired
- 1985-01-14 NO NO850154A patent/NO160576C/no unknown
- 1985-01-15 NZ NZ210839A patent/NZ210839A/en unknown
- 1985-01-15 GR GR850106A patent/GR850106B/el unknown
- 1985-01-15 ES ES539566A patent/ES8609230A1/es not_active Expired
- 1985-01-16 IL IL74068A patent/IL74068A/xx unknown
- 1985-01-16 DE DE8585300276T patent/DE3560717D1/de not_active Expired
- 1985-01-16 ZW ZW10/85A patent/ZW1085A1/xx unknown
- 1985-01-16 EP EP85300276A patent/EP0168902B1/en not_active Expired
- 1985-01-17 DK DK21085A patent/DK21085A/da unknown
- 1985-01-17 PT PT79835A patent/PT79835B/pt unknown
- 1985-01-17 FI FI850226A patent/FI79698C/fi not_active IP Right Cessation
- 1985-01-17 HU HU85199A patent/HU195638B/hu not_active IP Right Cessation
- 1985-01-18 AU AU37779/85A patent/AU571635B2/en not_active Ceased
- 1985-01-19 KR KR1019850000304A patent/KR900000683B1/ko not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI850226L (fi)	1985-07-20
NO850154L (no)	1985-07-22
EP0168902B1 (en)	1987-09-30
CA1243035A (en)	1988-10-11
EP0168902A1 (en)	1986-01-22
PT79835B (en)	1986-10-28
FI79698C (fi)	1990-02-12
AU571635B2 (en)	1988-04-21
HUT37748A (en)	1986-02-28
KR850005407A (ko)	1985-08-26
ZW1085A1 (en)	1985-04-24
HU195638B (en)	1988-06-28
IL74068A (en)	1988-08-31
DE3560717D1 (en)	1987-11-05
PT79835A (en)	1985-02-01
NZ210839A (en)	1987-10-30
KR900000683B1 (ko)	1990-02-03
AU3777985A (en)	1985-08-01
FI79698B (fi)	1989-10-31
GR850106B (fi)	1985-05-16
NO160576C (no)	1989-05-03
NO160576B (no)	1989-01-23
DK21085D0 (da)	1985-01-17
ES8609230A1 (es)	1986-07-16
DK21085A (da)	1985-07-20
ES539566A0 (es)	1986-07-16

Publication	Publication Date	Title
FI83882B (fi)	1991-05-31	Foerfarande foer framstaellning av blodlevring haemmande proteiner.
FI80896B (fi)	1990-04-30	Foerfarande foer framstaellning av fenolskum.
FI840174A (fi)	1985-07-18	Foerfarande foer optisk maetning av laongstraeckta stycken.
FI841895A0 (fi)	1984-05-11	Foerfarande foer framstaellning av flerskiktskartong.
FI841905A0 (fi)	1984-05-11	Foerfarande foer framstaellning av konstmarmoralster.
FI840758A (fi)	1985-08-25	Anlaeggning foer utnyttjande av vaermeenergi alstrad av en bastuugn.
FI842155A (fi)	1985-12-01	Anordning foer skaerning av skivor.
FI841768A0 (fi)	1984-05-03	Anordning foer rullning av traedstammar.
FI841518A0 (fi)	1984-04-16	Foerfarande foer framstaellning av stabila injektionspreparat av indolylalifatiska syraderivat.
FI80875B (fi)	1990-04-30	Framstaellning av isobutyrylfluorid.
FI841133A0 (fi)	1984-03-21	Anordning foer spridning av goedsel.
FI841802A (fi)	1985-11-05	Anordning foer foerflyttning av skivpaket.
FI841139A (fi)	1985-09-22	Anordning foer inledning av ledningar.
FI841276A0 (fi)	1984-03-30	Anordning foer foerflyttning av betongroer och -ringar.
FI841329A0 (fi)	1984-04-03	Anordning foer skaerpning av knivar.
FI841339A0 (fi)	1984-04-04	Foerfarande foer stoedande av gamla konstruktioner.
FI841365A0 (fi)	1984-04-05	Cellenhet foer skolning av plantor.
FI841366A (fi)	1985-10-06	Foerfarande foer kokning av foerhydrolyssulfatcellulosa.
FI841371A0 (fi)	1984-04-06	Foerfarande foer framstaellning av integrerade kretsar av mos-typ.
FI841478A (fi)	1985-10-14	Foerfarande foer framstaellning av en kulformad kopplingsdel foer vaetskeavspaerrningsorgan.
FI841007A (fi)	1985-09-14	Foerfarande foer fraesning av slaggskikt.
FI841565A0 (fi)	1984-04-18	Foerfarande foer reglering av stickkraft av bildaecksdubbar.
FI841574A0 (fi)	1984-04-19	Bindplaot speciellt foer byggande av traestavar.
FI841634A0 (fi)	1984-04-25	Foerfarande foer framstaellning av tonade paelsvaror.
FI840654A (fi)	1985-08-18	Fjaederanordning foer hindrande av foerslappning av bindning.

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: SMITHKLINE BECKMAN CORPORATION