FI792567A - Nya spiro-oxazolidinoner - Google Patents

Nya spiro-oxazolidinoner

Info

Publication number: FI792567A
Authority: FI; Finland
Prior art keywords: oxazolidinoner; nya; spiro; nya spiro
Prior art date: 1978-08-21

Application number

FI792567A

Other languages

English (en)

Other versions

FI65255B (fi

FI65255C (fi

Inventor

Rodney Caughren Schnur

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-08-21

Filing date

1979-08-17

Publication date

1980-02-22

1979-08-17 Application filed by Pfizer filed Critical Pfizer

1980-02-22 Publication of FI792567A publication Critical patent/FI792567A/fi

1983-12-30 Publication of FI65255B publication Critical patent/FI65255B/fi

1984-04-10 Application granted granted Critical

1984-04-10 Publication of FI65255C publication Critical patent/FI65255C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Photosensitive Polymer And Photoresist Processing (AREA)
Moulding By Coating Moulds (AREA)
Dental Preparations (AREA)

FI792567A 1978-08-21 1979-08-17 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara spiro(4h-2,3-dihydrobenzopyran(4,5')oxazolidin)-2',4'-dioner FI65255C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US93519978		1978-08-21
US05/935,199 US4200642A (en)	1978-08-21	1978-08-21	Spiro-oxazolidindiones

Publications (3)

Publication Number	Publication Date
FI792567A true FI792567A (fi)	1980-02-22
FI65255B FI65255B (fi)	1983-12-30
FI65255C FI65255C (fi)	1984-04-10

Family

ID=25466700

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI792567A FI65255C (fi)	1978-08-21	1979-08-17	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara spiro(4h-2,3-dihydrobenzopyran(4,5')oxazolidin)-2',4'-dioner

Country Status (34)

Country	Link
US (1)	US4200642A (fi)
JP (4)	JPS6011914B2 (fi)
AR (1)	AR225614A1 (fi)
AT (1)	AT366689B (fi)
AU (1)	AU535170B2 (fi)
BE (1)	BE878311A (fi)
CA (1)	CA1121361A (fi)
CH (1)	CH639974A5 (fi)
CS (1)	CS208129B2 (fi)
DD (1)	DD146602A5 (fi)
DE (2)	DE2933441C2 (fi)
DK (1)	DK258479A (fi)
EG (1)	EG14639A (fi)
ES (1)	ES483511A1 (fi)
FI (1)	FI65255C (fi)
FR (3)	FR2442851A1 (fi)
GB (2)	GB2028318B (fi)
GR (1)	GR71913B (fi)
HU (1)	HU179746B (fi)
IE (1)	IE48932B1 (fi)
IL (1)	IL58076A (fi)
IN (1)	IN152416B (fi)
IT (1)	IT1123536B (fi)
LU (1)	LU81613A1 (fi)
NL (1)	NL7906318A (fi)
NO (1)	NO792699L (fi)
NZ (1)	NZ191350A (fi)
PH (1)	PH18091A (fi)
PL (1)	PL130686B1 (fi)
PT (1)	PT70086A (fi)
SE (1)	SE447116B (fi)
SU (1)	SU942597A3 (fi)
YU (1)	YU41488B (fi)
ZA (1)	ZA794379B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4329459A (en) *	1980-05-05	1982-05-11	The Upjohn Company	Tetrahydrobenzopyran derivatives
GB2080803B (en) *	1980-07-28	1984-01-18	Pfizer	Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4367234A (en) *	1980-07-28	1983-01-04	Pfizer Inc.	Hypoglycemic 5-substituted oxazolidine-2,4-diones
ES515751A0 (es) *	1981-10-13	1983-10-16	Pfizer	"un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona".
US4540700A (en) *	1982-04-15	1985-09-10	Alcon Laboratories, Inc.	Treatment of diabetic complications with certain spiro-imidazolidine-diones
US4436745A (en)	1982-04-15	1984-03-13	Alcon Laboratories, Inc.	Method of inhibiting aldose reductase activity
US4438272A (en)	1982-04-15	1984-03-20	Alcon Laboratories, Inc.	Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones
US4464385A (en) *	1982-04-15	1984-08-07	Alcon Laboratories, Inc.	Treatment of diabetic complications with hydantoins
ZA832679B (en) *	1982-05-07	1983-12-28	Ici Plc	Indoline derivatives
US4430337A (en)	1982-06-23	1984-02-07	Pfizer Inc.	Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US4556670A (en) *	1982-12-06	1985-12-03	Pfizer Inc.	Spiro-3-hetero-azolones for treatment of diabetic complications
US4533667A (en) *	1983-05-25	1985-08-06	Pfizer Inc.	Imidazolidinedione derivatives
US4464380A (en) *	1983-05-25	1984-08-07	Pfizer Inc.	Imidazolidinedione derivatives
DK277484A (da) *	1983-06-23	1984-12-24	Hoffmann La Roche	Thiazolidinderivater
JPS61200991A (ja) *	1985-03-04	1986-09-05	Sanwa Kagaku Kenkyusho:Kk	スピロ―３―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤
DE3522791C1 (en) *	1985-06-26	1987-01-02	Ferroplast Gmbh	Positioning wall for lagging a cavity to be filled with a hardenable material in mining or tunnelling
WO1987004344A1 (en) *	1986-01-17	1987-07-30	Pfizer Inc.	Hydroxyacetic acid derivatives for the treatment of diabetic complications
US5039672A (en) *	1990-04-05	1991-08-13	Pfizer Inc.	Heterocyclic compounds as aldose reductase inhibitors
US5068332A (en) *	1990-10-12	1991-11-26	American Home Products Corporation	Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
US5102886A (en) *	1990-10-12	1992-04-07	American Home Products Corporation	1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors
FR2707981B1 (fr) *	1993-07-20	1995-09-01	Adir	Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
AU773505B2 (en)	1999-06-18	2004-05-27	Merck & Co., Inc.	Arylthiazolidinedione and aryloxazolidinedione derivatives
ES2277842T3 (es)	1999-06-18	2007-08-01	MERCK & CO., INC.	Derivados de ariltiazolidindiona y de ariloxazolidindiona.
ITPI20060083A1 (it) *	2006-07-11	2008-01-12	Univ Pisa	Derivati 2,2-dimetilcromanici 4-spiro-eterocicilici azotati (a 5 e 6 termini) n-sostituiti quali cardio-protettori nei confronti dell'insulto ischemico
USD775790S1 (en) *	2015-11-18	2017-01-10	Ginger Damon	Motorcycle jacket
RU2748513C1 (ru)	2017-12-21	2021-05-26	Эссити Хайджин Энд Хелт Актиеболаг	Впитывающее изделие и способ изготовления впитывающего изделия
JP2021507767A (ja)	2017-12-21	2021-02-25	エシティ・ハイジーン・アンド・ヘルス・アクチエボラグ	吸収性物品及び吸収性物品を製造する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1204232B (de) *	1959-07-16	1965-11-04	Ncr Co	Verfahren zur Herstellung von Derivaten von 3-Alkyl-3'-methyl-spiro[benzoxazolin-2, 2'-(2'H-1'-benzopyran)]
US3532744A (en) *	1967-07-28	1970-10-06	American Home Prod	1- and 2-amino substituted indane and tetralene carboxylic acids
US3821383A (en) *	1972-07-10	1974-06-28	Ayerst Mckenna & Harrison	Compositions for and a method of treating diabetic complications
CA1088945A (en) *	1976-10-18	1980-11-04	Pfizer Limited	Hydantoin derivatives as therapeutic agents

1978
- 1978-08-21 US US05/935,199 patent/US4200642A/en not_active Expired - Lifetime
1979
- 1979-06-20 DK DK258479A patent/DK258479A/da not_active Application Discontinuation
- 1979-06-21 IN IN451/DEL/79A patent/IN152416B/en unknown
- 1979-07-27 GB GB7926348A patent/GB2028318B/en not_active Expired
- 1979-08-16 YU YU1999/79A patent/YU41488B/xx unknown
- 1979-08-16 CH CH752879A patent/CH639974A5/fr not_active IP Right Cessation
- 1979-08-17 FI FI792567A patent/FI65255C/fi not_active IP Right Cessation
- 1979-08-17 DE DE2933441A patent/DE2933441C2/de not_active Expired
- 1979-08-17 HU HU79PI685A patent/HU179746B/hu unknown
- 1979-08-17 CA CA000333955A patent/CA1121361A/en not_active Expired
- 1979-08-17 DE DE2953954A patent/DE2953954C2/de not_active Expired
- 1979-08-18 JP JP54105459A patent/JPS6011914B2/ja not_active Expired
- 1979-08-20 AU AU50092/79A patent/AU535170B2/en not_active Ceased
- 1979-08-20 IT IT25182/79A patent/IT1123536B/it active
- 1979-08-20 LU LU81613A patent/LU81613A1/fr unknown
- 1979-08-20 SU SU792803649A patent/SU942597A3/ru active
- 1979-08-20 IE IE1592/79A patent/IE48932B1/en not_active IP Right Cessation
- 1979-08-20 PT PT70086A patent/PT70086A/pt unknown
- 1979-08-20 AT AT0560579A patent/AT366689B/de not_active IP Right Cessation
- 1979-08-20 SE SE7906949A patent/SE447116B/sv not_active IP Right Cessation
- 1979-08-20 ES ES483511A patent/ES483511A1/es not_active Expired
- 1979-08-20 IL IL58076A patent/IL58076A/xx unknown
- 1979-08-20 EG EG79509A patent/EG14639A/xx active
- 1979-08-20 ZA ZA00794379A patent/ZA794379B/xx unknown
- 1979-08-20 NZ NZ191350A patent/NZ191350A/en unknown
- 1979-08-20 FR FR7920969A patent/FR2442851A1/fr active Granted
- 1979-08-20 BE BE0/196785A patent/BE878311A/fr not_active IP Right Cessation
- 1979-08-20 NO NO792699A patent/NO792699L/no unknown
- 1979-08-20 GR GR59870A patent/GR71913B/el unknown
- 1979-08-21 NL NL7906318A patent/NL7906318A/nl active Search and Examination
- 1979-08-21 PL PL1979217881A patent/PL130686B1/pl unknown
- 1979-08-21 CS CS795699A patent/CS208129B2/cs unknown
- 1979-08-21 DD DD79215099A patent/DD146602A5/de unknown
- 1979-08-21 PH PH22931A patent/PH18091A/en unknown
- 1979-08-21 AR AR277784A patent/AR225614A1/es active
- 1979-08-27 GB GB8001161A patent/GB2033904B/en not_active Expired
- 1979-11-16 JP JP54148749A patent/JPS5943954B2/ja not_active Expired
- 1979-11-16 JP JP54148747A patent/JPS5946517B2/ja not_active Expired
- 1979-11-16 JP JP54148748A patent/JPS6011915B2/ja not_active Expired
1980
- 1980-02-07 FR FR8002697A patent/FR2440949A1/fr active Granted
- 1980-02-07 FR FR8002698A patent/FR2440950A1/fr active Granted

Also Published As

Publication number	Publication date
JPS6011915B2 (ja)	1985-03-28
AR225614A1 (es)	1982-04-15
AT366689B (de)	1982-04-26
FR2440949B1 (fi)	1981-06-12
JPS5528996A (en)	1980-02-29
IE48932B1 (en)	1985-06-26
FR2442851A1 (fr)	1980-06-27
AU535170B2 (en)	1984-03-08
NO792699L (no)	1980-02-22
US4200642A (en)	1980-04-29
CA1121361A (en)	1982-04-06
SE7906949L (sv)	1980-02-22
NL7906318A (nl)	1980-02-25
GR71913B (fi)	1983-08-16
DE2953954C2 (fi)	1987-12-03
PH18091A (en)	1985-03-20
DE2953954A1 (fi)	1982-09-02
GB2033904B (en)	1982-08-04
AU5009279A (en)	1980-02-28
PT70086A (en)	1979-09-01
IT1123536B (it)	1986-04-30
HU179746B (en)	1982-12-28
IL58076A0 (en)	1979-12-30
FI65255B (fi)	1983-12-30
EG14639A (en)	1985-03-31
IL58076A (en)	1982-07-30
ES483511A1 (es)	1980-09-01
FR2440950A1 (fr)	1980-06-06
IT7925182A0 (it)	1979-08-20
JPS5943954B2 (ja)	1984-10-25
PL217881A1 (fi)	1981-01-02
GB2028318A (en)	1980-03-05
YU199979A (en)	1983-06-30
SU942597A3 (ru)	1982-07-07
CS208129B2 (en)	1981-08-31
YU41488B (en)	1987-08-31
CH639974A5 (fr)	1983-12-15
LU81613A1 (fr)	1980-04-21
PL130686B1 (en)	1984-08-31
BE878311A (fr)	1980-02-20
DE2933441A1 (de)	1980-02-28
FR2440950B1 (fi)	1981-06-12
IE791592L (en)	1980-02-21
DK258479A (da)	1980-02-22
JPS6011914B2 (ja)	1985-03-28
NZ191350A (en)	1984-04-27
GB2028318B (en)	1982-08-04
DD146602A5 (de)	1981-02-18
FR2442851B1 (fi)	1983-06-17
JPS55129279A (en)	1980-10-06
JPS5946517B2 (ja)	1984-11-13
FI65255C (fi)	1984-04-10
ATA560579A (de)	1981-09-15
IN152416B (fi)	1984-01-07
SE447116B (sv)	1986-10-27
GB2033904A (en)	1980-05-29
ZA794379B (en)	1980-08-27
JPS55129288A (en)	1980-10-06
JPS55129280A (en)	1980-10-06
FR2440949A1 (fr)	1980-06-06
DE2933441C2 (de)	1987-04-23

Publication	Publication Date	Title
FI791084A (fi)	1979-10-04	Nya n-heterocyklo-4-piperidinaminer
FI791678A (fi)	1979-11-27	Foerfarande foer framstaellning av nya kefalosporinantibiotika
FI791754A (fi)	1979-11-26	Nya aminotiazoler
FI792082A (fi)	1980-01-04	Framstaellning av nya fenetanolaminer
FI791034A (fi)	1979-10-01	Nya karbostyrilderivat och foerfarande foer deras framstaellning
FI792699A (fi)	1980-03-02	Nya tetrazolylalkoxikarbostyrilderivat och foerfarande foer deras framstaellning
FI792628A (fi)	1980-02-26	Nya benzimidazolider deras framstaellning och deras anvaendning saosom laekemedel
FI793142A (fi)	1980-04-19	Nya metaboliter deras framstaellning och anvaendning
FI792075A (fi)	1981-01-03	Kopplare
DK103879A (da)	1979-09-14	Mufferoer
AT365922B (de)	1982-02-25	Netzbett
FI792567A (fi)	1980-02-22	Nya spiro-oxazolidinoner
FI790328A (fi)	1979-08-02	Elektrisk styrkrets
FI792315A (fi)	1980-02-01	Nya staerkelser innehaollande livsmedelsprodukter och foerfarande foer deras framstaellning
AT374352B (de)	1984-04-10	Sportschuh
FI791679A (fi)	1979-11-27	Foerfarande foer framstaellning av nya kefalosporinantibiotika
FI792347A (fi)	1980-01-28	Nya indanylderivat deras framstaellning och anvaendning
FI792080A (fi)	1980-01-04	Framstaellning av nya fenetanolaminer
FI790050A (fi)	1979-07-17	Nya penicilliner och kefalosporiner deras framstaellning och anvaendning saosom antibakteriska aemnen
FI792927A (fi)	1980-03-30	Nya galeniska laekemedelsdoseringsformer och foerfarande foer deras framstaellning
FI803403L (fi)	1981-05-01	Nya pyridotienotriaziner
AR218561A1 (es)	1980-06-13	Copoliester p-oxibenzoilico
SE7909023L (sv)	1980-05-02	Nya azolylketaler
FI790820A (fi)	1979-09-16	Foerfarande foer framstaellning av nya n-fenylalaninderivat
FI791733A (fi)	1979-12-09	Nya metaboliter deras framstaellning och anvaendning

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: PFIZER INC.