FI782994A - Foerfarande foer framstaellning av nya piperazinopyrrolobensodiazepiner - Google Patents

Foerfarande foer framstaellning av nya piperazinopyrrolobensodiazepiner

Info

Publication number: FI782994A
Authority: FI; Finland
Prior art keywords: piperazinopyrrolobensodiazepiner; nya; framstaellning; framework; piperazinopyrrolobensodiazepiner framstaellning
Prior art date: 1977-10-05

Application number

FI782994A

Other languages

English (en)

Other versions

FI63578B (fi

FI63578C (fi

Inventor

Jan W F Wasley

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-10-05

Filing date

1978-10-02

Publication date

1979-04-06

1978-10-02 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1979-04-06 Publication of FI782994A publication Critical patent/FI782994A/fi

1983-03-31 Publication of FI63578B publication Critical patent/FI63578B/fi

1983-07-11 Application granted granted Critical

1983-07-11 Publication of FI63578C publication Critical patent/FI63578C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI782994A 1977-10-05 1978-10-02 Analogifoerfarande foer framstaellning av nya farmakologiskt verksamma 1,3,4,14b-tetrahydro-2h 10h-pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)bensodiazepiner FI63578C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US83969677A	1977-10-05	1977-10-05
US83969677		1977-10-05

Publications (3)

Publication Number	Publication Date
FI782994A true FI782994A (fi)	1979-04-06
FI63578B FI63578B (fi)	1983-03-31
FI63578C FI63578C (fi)	1983-07-11

Family

ID=25280422

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI782994A FI63578C (fi)	1977-10-05	1978-10-02	Analogifoerfarande foer framstaellning av nya farmakologiskt verksamma 1,3,4,14b-tetrahydro-2h 10h-pyrazino(1,2-a)pyrrolo(2,1-c)(1,4)bensodiazepiner

Country Status (18)

Country	Link
EP (1)	EP0001585B1 (fi)
JP (1)	JPS5461199A (fi)
AT (1)	AT368157B (fi)
AU (1)	AU521335B2 (fi)
CA (1)	CA1113934A (fi)
DD (1)	DD138774A5 (fi)
DE (1)	DE2860861D1 (fi)
DK (1)	DK441278A (fi)
ES (1)	ES473900A1 (fi)
FI (1)	FI63578C (fi)
HK (1)	HK2185A (fi)
HU (1)	HU179948B (fi)
IE (1)	IE47390B1 (fi)
IL (1)	IL55664A (fi)
NO (1)	NO150159C (fi)
NZ (1)	NZ188580A (fi)
SG (1)	SG38684G (fi)
ZA (2)	ZA784475B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4737496A (en) *	1986-10-01	1988-04-12	Ciba-Geigy Corporation	1,3,4,16b-tetrahydro-2H,10H-indolo[2,1-c]pyrazino-[1,2-a][1,4]benzodiazepines useful as serotonin-2 receptor antagonists
NO175781C (no) *	1989-10-05	1994-12-07	Sankyo Co	Analogifremgangsmåte for fremstilling av terapeutisk aktive tetracykliske forbindelser
EP0539164A1 (en) *	1991-10-23	1993-04-28	Sankyo Company Limited	Nitrogen-containing tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
AUPP433398A0 (en) *	1998-06-25	1998-07-16	Australian National University, The	Compounds and processes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3763183A (en) *	1972-07-10	1973-10-02	Sterling Drug Inc	1,2,3,10,11,11a-hexahydro-5h-pyrrolo (2,1-c)(1,4)benzodiazepines
US3985732A (en) *	1974-04-26	1976-10-12	American Cyanamid Company	1,2,3,11A-Tetrahydro-10-methyl-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5,11(10H)-diones
US3984562A (en) *	1975-02-24	1976-10-05	American Cyanamid Company	Substituted benzodiazepines and method of use
US4017492A (en) *	1976-04-02	1977-04-12	The Upjohn Company	As-triazinobenzodiazepin-1-ones
US4073784A (en) *	1977-03-09	1978-02-14	The Upjohn Company	Certain as-triazino 4,3-a! 1,4!benzodiazepine-1,2-dione compounds

1978
- 1978-08-08 ZA ZA00784475A patent/ZA784475B/xx unknown
- 1978-09-29 IL IL55664A patent/IL55664A/xx unknown
- 1978-10-02 EP EP78101052A patent/EP0001585B1/de not_active Expired
- 1978-10-02 DE DE7878101052T patent/DE2860861D1/de not_active Expired
- 1978-10-02 FI FI782994A patent/FI63578C/fi not_active IP Right Cessation
- 1978-10-03 DD DD78208254A patent/DD138774A5/xx unknown
- 1978-10-03 CA CA312,550A patent/CA1113934A/en not_active Expired
- 1978-10-03 ES ES473900A patent/ES473900A1/es not_active Expired
- 1978-10-04 ZA ZA00785599A patent/ZA785599B/xx unknown
- 1978-10-04 IE IE1985/78A patent/IE47390B1/en unknown
- 1978-10-04 NO NO783360A patent/NO150159C/no unknown
- 1978-10-04 HU HU78CI1862A patent/HU179948B/hu unknown
- 1978-10-04 AT AT0715178A patent/AT368157B/de not_active IP Right Cessation
- 1978-10-04 NZ NZ188580A patent/NZ188580A/xx unknown
- 1978-10-04 AU AU40401/78A patent/AU521335B2/en not_active Expired
- 1978-10-04 DK DK441278A patent/DK441278A/da not_active Application Discontinuation
- 1978-10-05 JP JP12212178A patent/JPS5461199A/ja active Pending
1984
- 1984-05-23 SG SG386/84A patent/SG38684G/en unknown
1985
- 1985-01-10 HK HK21/85A patent/HK2185A/xx unknown

Also Published As

Publication number	Publication date
FI63578B (fi)	1983-03-31
FI63578C (fi)	1983-07-11
HU179948B (en)	1983-01-28
EP0001585A1 (de)	1979-05-02
CA1113934A (en)	1981-12-08
DE2860861D1 (en)	1981-10-29
ZA785599B (en)	1979-09-26
AU4040178A (en)	1980-04-17
ATA715178A (de)	1982-01-15
DD138774A5 (de)	1979-11-21
NZ188580A (en)	1981-12-15
IE47390B1 (en)	1984-03-07
ZA784475B (en)	1979-07-25
NO150159C (no)	1984-08-29
EP0001585B1 (de)	1981-07-22
DK441278A (da)	1979-04-06
JPS5461199A (en)	1979-05-17
HK2185A (en)	1985-01-18
NO783360L (no)	1979-04-06
AT368157B (de)	1982-09-27
AU521335B2 (en)	1982-03-25
NO150159B (no)	1984-05-21
SG38684G (en)	1985-03-29
IL55664A (en)	1982-02-28
ES473900A1 (es)	1979-04-16
IE781985L (en)	1979-04-05
IL55664A0 (en)	1978-12-17

Publication	Publication Date	Title
FI781811A (fi)	1978-12-11	Nya carbostyrilderivat
FI782931A (fi)	1979-03-31	Nya aemnessammansaettningar
FI782907A (fi)	1979-03-29	Nya cyklopeptider
FI780589A (fi)	1978-09-15	Nya 4-acylamino-fenyl-etanolaminer
FI782157A (fi)	1979-01-12	Foerfarande foer framstaellning av nya 1-asyl-2-cyanaziridiner
FI781933A (fi)	1978-12-21	Nya peptidderivat
FI783325A (fi)	1979-05-04	Nya derivat av kinazolin
FI782481A (fi)	1979-02-16	Foerfarande foer framstaellning av nya organiska foereningar
FI803547L (fi)	1981-05-16	Foerfaranden foer framstaellning av nya piperidylbensimidazolinoner
FI781461A (fi)	1978-11-17	Foerfarande foer framstaellning av nya alkylendiaminderivat
SE7811457L (sv)	1979-05-08	Nya kinolylguanidinderivat
FI773717A (fi)	1978-07-23	Nya aminoalkoxifenylderivater
FI783846A (fi)	1979-06-21	Nya bredspektriga cefalosporinantibioter
FI781674A (fi)	1978-12-02	Nya fluoriderade aminosyror
SE7810050L (sv)	1979-03-27	Nya 7-azabensimidazoler
FI781779A (fi)	1978-12-16	Foerfarande foer framstaellning av nya nitroso-urinaemnen
FI782228A (fi)	1979-01-16	Foerfarande foer framstaellning av nya bensopyranderivat
FI782039A (fi)	1979-02-11	Nya 2-pyridyl- och 2-pyrimidylaminobensoesyror
FI782011A (fi)	1979-01-22	Nya imidazo-isokinolin-dioner
FI782574A (fi)	1979-03-02	Foerfarande foer framstaellning av n-substituerade 2-hydrazonopropionsyraderivat
FI780444A (fi)	1978-08-19	Foerfarande foer framstaellning av nya oximderivat av 3-tiadiazolyltiometyl-7-aminotiazolacetamido-cefalosporansyra
FI781515A (fi)	1978-11-18	Foerfarande foer framstaellning av azacyklylfoereningar
SE7804318L (sv)	1978-11-03	Nya naftyridiner
FI784017A (fi)	1979-09-18	Foerfarande foer framstaellning av nya arylaminoimidazolinderivater
FI781886A (fi)	1978-12-14	Foerfarande foer framstaellning av nya pyridazinylhydrazoner

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: CIBA-GEIGY AG