[go: up one dir, main page]

FI73986B - Analogifoerfarande foer framstaellning av 1-piperazinkarboxamider. - Google Patents

Analogifoerfarande foer framstaellning av 1-piperazinkarboxamider.

Info

Publication number
FI73986B
FI73986B FI793238A FI793238A FI73986B FI 73986 B FI73986 B FI 73986B FI 793238 A FI793238 A FI 793238A FI 793238 A FI793238 A FI 793238A FI 73986 B FI73986 B FI 73986B
Authority
FI
Finland
Prior art keywords
piperazinkarboxamider
analogificant
faring
framstaellning
compounds
Prior art date
Application number
FI793238A
Other languages
English (en)
Other versions
FI793238A (fi
FI73986C (fi
Inventor
Anders Karl Konrad Bjoerk
Knut Gunnar Olsson
Aina Lisbeth Abramo
Erik Gunnar Christensson
Original Assignee
Ferrosan Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan Ab filed Critical Ferrosan Ab
Publication of FI793238A publication Critical patent/FI793238A/fi
Publication of FI73986B publication Critical patent/FI73986B/fi
Application granted granted Critical
Publication of FI73986C publication Critical patent/FI73986C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194—Radicals derived from thio- or thiono carboxylic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B01L1/52—Transportable laboratories; Field kits

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI793238A 1978-10-20 1979-10-18 Analogifoerfarande foer framstaellning av 1-piperazinkarboxamider. FI73986C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE7810971 1978-10-20
SE7810971 1978-10-20

Publications (3)

Publication Number Publication Date
FI793238A FI793238A (fi) 1980-04-21
FI73986B true FI73986B (fi) 1987-08-31
FI73986C FI73986C (fi) 1987-12-10

Family

ID=20336152

Family Applications (1)

Application Number Title Priority Date Filing Date
FI793238A FI73986C (fi) 1978-10-20 1979-10-18 Analogifoerfarande foer framstaellning av 1-piperazinkarboxamider.

Country Status (21)

Country Link
US (3) US4308387A (fi)
JP (1) JPS5557572A (fi)
AT (1) AT376666B (fi)
AU (1) AU529260B2 (fi)
BE (1) BE879528A (fi)
CA (1) CA1130807A (fi)
CH (1) CH643247A5 (fi)
DE (1) DE2941880A1 (fi)
DK (1) DK149057C (fi)
ES (1) ES485188A1 (fi)
FI (1) FI73986C (fi)
FR (1) FR2439187A1 (fi)
GB (1) GB2037745B (fi)
HK (1) HK57184A (fi)
IT (1) IT1207269B (fi)
LU (1) LU81807A1 (fi)
NL (2) NL190160C (fi)
NO (1) NO154582C (fi)
NZ (1) NZ191867A (fi)
SE (1) SE448730B (fi)
SG (1) SG7384G (fi)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791501A (fr) * 1971-11-19 1973-05-17 Albert Ag Chem Werke Diamines cycliques n,n'-disubstituees et leur procede de preparation
WO1981003658A1 (en) * 1980-06-16 1981-12-24 Ferrosan Ab Diphenylbutyl-1-acylpiperazines
IL67372A (en) * 1981-12-02 1986-04-29 Ferrosan Ab Pharmaceutical compositions comprising 4-(4,4-bis(p-fluorophenyl)butyl)-1-piperazinocarboxylates,certain such novel compounds and their preparation
US4543352A (en) * 1983-04-29 1985-09-24 William H. Rorer, Inc. Naphthalene aminoalkylene ethers and thioethers, and their pharmaceutical uses
AT387572B (de) * 1983-05-20 1989-02-10 Ferrosan Ab Verfahren zur herstellung von neuen 4-(4,4-bis-(p-fluorphenyl)-butyl)-1-carbophenox -piperazinen und von 1-piperazincarboxamiden
ES8502099A1 (es) 1983-08-02 1984-12-16 Espanola Farma Therapeut Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina.
SE8304361D0 (sv) * 1983-08-10 1983-08-10 Ferrosan Ab Novel 1-acylpiperazine derivatives novel 1-acylpiperazine derivatives
FR2558162B1 (fr) * 1984-01-17 1986-04-25 Adir Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
SE8500573D0 (sv) * 1985-02-08 1985-02-08 Ferrosan Ab Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain
US4960776A (en) * 1987-01-28 1990-10-02 A. H. Robins Company, Inc. 4-aryl-N-(alkylaminoalkyl, heterocyclicamino and heterocyclicamino)alkyl)-1-piperazinecarboxamides
WO1990013539A1 (en) * 1989-04-28 1990-11-15 Meiji Seika Kaisha, Ltd. New n-substituted piperazine derivatives and drug for improving functional disorder of brain
FR2673182A1 (fr) * 1991-02-22 1992-08-28 Univ Caen Piperazines n,n'-disubstituees, leur procede de preparation et leur application en therapeutique.
SE9100860D0 (sv) * 1991-03-22 1991-03-22 Kabi Pharmacia Ab New use
SE9201239D0 (sv) * 1992-04-21 1992-04-21 Kabi Pharmacia Ab Agents for treating substance abuse disorders
DE4219973A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
SE9202266D0 (sv) * 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel piperazine carboxamides
DE4307181C1 (de) * 1993-03-08 1994-11-10 Dresden Arzneimittel Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid
DE4341403A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung
JP3274579B2 (ja) * 1995-01-12 2002-04-15 住友製薬株式会社 脳血管障害に伴う精神症候治療剤
DE29815747U1 (de) 1998-09-02 2000-01-05 Ramsauer, Dieter, 42555 Velbert Anschraubscharnier mit Raststellung
GB9923748D0 (en) * 1999-10-07 1999-12-08 Glaxo Group Ltd Chemical compounds
USRE39921E1 (en) 1999-10-07 2007-11-13 Smithkline Beecham Corporation Chemical compounds
GB0025354D0 (en) * 2000-10-17 2000-11-29 Glaxo Group Ltd Chemical compounds
GB0108594D0 (en) * 2001-04-05 2001-05-23 Glaxo Group Ltd Chemical compounds
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US7842307B2 (en) * 2001-08-06 2010-11-30 Purdue Pharma L.P. Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent
US20030044458A1 (en) * 2001-08-06 2003-03-06 Curtis Wright Oral dosage form comprising a therapeutic agent and an adverse-effect agent
US7332182B2 (en) 2001-08-06 2008-02-19 Purdue Pharma L.P. Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant
US7141250B2 (en) * 2001-08-06 2006-11-28 Euro-Celtique S.A. Pharmaceutical formulation containing bittering agent
US7157103B2 (en) 2001-08-06 2007-01-02 Euro-Celtique S.A. Pharmaceutical formulation containing irritant
WO2003066589A1 (en) * 2002-02-08 2003-08-14 Glaxo Group Limited Piperidylcarboxamide derivatives and their use in the treatment of tachykinim-mediated diseases
GB0203022D0 (en) * 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
GB0203020D0 (en) 2002-02-08 2002-03-27 Glaxo Group Ltd Chemical compounds
PT1765292T (pt) 2004-06-12 2017-12-29 Collegium Pharmaceutical Inc Formulações de fármacos dissuasoras de abuso
JP4823673B2 (ja) * 2005-12-15 2011-11-24 タカラベルモント株式会社 ショックレス弁を接続した油圧回路
JP2010169206A (ja) * 2009-01-23 2010-08-05 Finesinter Co Ltd ノンリークショックレス電磁比例制御弁
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
PT2826467T (pt) 2010-12-22 2017-10-25 Purdue Pharma Lp Formas envolvidas de dosamento de libertação controlada resistentes à adulteração
PH12013501345A1 (en) 2010-12-23 2022-10-24 Purdue Pharma Lp Tamper resistant solid oral dosage forms
JP6208261B2 (ja) 2013-02-05 2017-10-04 パーデュー、ファーマ、リミテッド、パートナーシップＰｕｒｄｕｅ Ｐｈａｒｍａ Ｌ．Ｐ． タンパリング抵抗性医薬製剤
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US9737530B1 (en) 2016-06-23 2017-08-22 Collegium Pharmaceutical, Inc. Process of making stable abuse-deterrent oral formulations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137318C (fi) * 1964-06-09
JPS518283A (en) * 1974-07-09 1976-01-23 Kyorin Seiyaku Kk 11 * 33 fuenirupuropiru * 44 karubamoirupiperajinjudotaino seizoho
JPS5346988A (en) * 1976-10-07 1978-04-27 Kyorin Seiyaku Kk Piperadine derivative

Also Published As

Publication number Publication date
HK57184A (en) 1984-08-03
DK149057C (da) 1986-06-02
NO154582B (no) 1986-07-28
ATA683479A (de) 1984-05-15
AT376666B (de) 1984-12-27
AU529260B2 (en) 1983-06-02
SG7384G (en) 1985-02-08
JPS6326756B2 (fi) 1988-05-31
JPS5557572A (en) 1980-04-28
DK442779A (da) 1980-04-21
ES485188A1 (es) 1980-05-16
SE448730B (sv) 1987-03-16
US4447433A (en) 1984-05-08
CA1130807A (en) 1982-08-31
GB2037745B (en) 1982-11-24
DK149057B (da) 1986-01-06
NO154582C (no) 1986-11-05
BE879528A (fr) 1980-04-21
DE2941880A1 (de) 1980-04-30
NL190160C (nl) 1993-11-16
NL190160B (nl) 1993-06-16
NO793315L (no) 1980-04-22
SE7908701L (sv) 1980-04-21
IT7926603A0 (it) 1979-10-18
AU5198479A (en) 1980-06-19
FI793238A (fi) 1980-04-21
DE2941880C2 (fi) 1989-04-20
NL7907741A (nl) 1980-04-22
US4308387A (en) 1981-12-29
NZ191867A (en) 1983-06-14
IT1207269B (it) 1989-05-17
CH643247A5 (de) 1984-05-30
FR2439187B1 (fi) 1983-03-18
FR2439187A1 (fr) 1980-05-16
NL940004I1 (nl) 1994-05-02
US4385057A (en) 1983-05-24
LU81807A1 (de) 1980-01-25
GB2037745A (en) 1980-07-16
FI73986C (fi) 1987-12-10

Similar Documents

Publication Publication Date Title
FI73986B (fi) Analogifoerfarande foer framstaellning av 1-piperazinkarboxamider.
SE8700498D0 (sv) Novel pharmaceologically active compounds
SE7614258L (sv) Forfarande for framstellning av kinazoloderivat
NO921835D0 (no) Fremgangsmaate for fremstilling av amidinofenylalaninderivat samt anvendelse derav
SE7902910L (sv) 4-tiazolidinkarboxylsyror
ES499485A0 (es) Procedimiento para la preparacion de derivados de cefalospo-rina
SE8204237L (sv) Karbostyrilforeningar, kompositioner innehallande dessa samt forfaranden for framstellning derav
SE8002322L (sv) Medel for behandling av inflammatoriska tarmsjukdomar
SE8404308D0 (sv) Polyprenylkarboxylsyraamider, forfarande for deras framstellning samt farmaceutiska kompositioner innehallande dessa foreningar
FI863565A0 (fi) Foerfarande foer framstaellning av nya pyrrobenzimidazoler, pyrrolbenzoxazoler och pyrrolbenztiazoler.
NO832164L (no) Fremgangsmaate for fremstilling av et terapeutisk aktivt tieno-pyridin-derivat
SE7609495L (sv) N-tetrahydrofurfuryl-noroximorfon, dess syraadditionssalter, lekemedel innehallande dessa samt forfarande for framstellning derav
ZA826453B (en) Tricyclic thiazolyloxamic acids and their derivatives,their preparation,and therapeutic agents containing these compounds
EP0009636A3 (en) 3-chloro-6-hydroxy-5-methylbenzoic acid derivative, corresponding pharmaceutical preparations, growth promoting compositions, the use of the compounds in the treatment and prophylaxis of diseases and for promoting growth of certain animals, and their manufacture
ES8307778A1 (es) Procedimiento para preparar difenilbutil-1-piperazinocarboxilatos.
SE8303719L (sv) Eburnan-oximderivat, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande dessa foreningar
SE8206128L (sv) Farmaceutisk komposition for behandling av njurstenar framkallade genom infektion
SE7907251L (sv) Nya metyl-l-piperidinol-4-estrar och sett att framstella dessa samt farmaceutiska kompositioner, innehallande nemnda estrar
SE7701504L (sv) Antihypertensiva medel
SE7907656L (sv) 3,4-dihydroxikanelaldehydderivat
IL61769A0 (en) 2-phenylamino-imidazolines-(2),their preparation and pharmaceutical compositions containing them
FI820172L (fi) Basiskt substituerade antranilsyror deras framstaellningsfoerfarande och anvaendning
ATE225T1 (de) Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben.
ATE1606T1 (de) Indanyloxaminsaeure-derivate, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
SE8202254L (sv) 2,4-dioxacyklohexanon-derivat

Legal Events

Date Code Title Description
PC Transfer of assignment of patent

Owner name: PHARMACIA AB

MA Patent expired

Owner name: PHARMACIA AB