FI69058C - Foerfarande foer framstaellning av terapeutiskt anvaendbara bi(nitrosoureido)polyolderivat - Google Patents
Foerfarande foer framstaellning av terapeutiskt anvaendbara bi(nitrosoureido)polyolderivat Download PDFInfo
- Publication number
- FI69058C FI69058C FI782238A FI782238A FI69058C FI 69058 C FI69058 C FI 69058C FI 782238 A FI782238 A FI 782238A FI 782238 A FI782238 A FI 782238A FI 69058 C FI69058 C FI 69058C
- Authority
- FI
- Finland
- Prior art keywords
- chloroethyl
- bis
- mixture
- nitrosoureido
- water
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/66—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to halogen atoms or to nitro or nitroso groups
- C07C275/68—N-nitroso ureas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Polyurethanes Or Polyureas (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HUGO001386 | 1977-12-29 | ||
HU77GO1386A HU176101B (en) | 1977-12-29 | 1977-12-29 | Process for producing bis-bracket-nitrozo-ureido-bracket closed-polyol derivatives |
Publications (3)
Publication Number | Publication Date |
---|---|
FI782238A FI782238A (fi) | 1979-06-30 |
FI69058B FI69058B (fi) | 1985-08-30 |
FI69058C true FI69058C (fi) | 1985-12-10 |
Family
ID=10996842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI782238A FI69058C (fi) | 1977-12-29 | 1978-07-13 | Foerfarande foer framstaellning av terapeutiskt anvaendbara bi(nitrosoureido)polyolderivat |
Country Status (28)
Country | Link |
---|---|
US (1) | US4237273A (pt) |
JP (1) | JPS5495517A (pt) |
AT (1) | AT360045B (pt) |
AU (1) | AU523845B2 (pt) |
BE (1) | BE868988A (pt) |
BG (1) | BG30016A3 (pt) |
CA (1) | CA1108182A (pt) |
CH (1) | CH639363A5 (pt) |
CS (1) | CS201010B2 (pt) |
DD (1) | DD137224A5 (pt) |
DE (1) | DE2831094A1 (pt) |
DK (1) | DK155047C (pt) |
ES (1) | ES471778A1 (pt) |
FI (1) | FI69058C (pt) |
FR (1) | FR2415096A1 (pt) |
GB (1) | GB2011382B (pt) |
GR (1) | GR64891B (pt) |
HU (1) | HU176101B (pt) |
IL (1) | IL55138A (pt) |
IT (1) | IT1097647B (pt) |
NL (1) | NL7807587A (pt) |
NO (1) | NO149960C (pt) |
PL (1) | PL112198B1 (pt) |
PT (1) | PT68301A (pt) |
RO (1) | RO77027A (pt) |
SE (1) | SE446529B (pt) |
YU (1) | YU41314B (pt) |
ZA (1) | ZA783980B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2459231A1 (fr) | 1979-06-19 | 1981-01-09 | Anvar | Nouveaux derives de la cystamine utiles comme medicaments |
JPS5775993A (en) * | 1980-10-30 | 1982-05-12 | Tetsuo Suami | Novel nitrosourea derivative and its preparation |
EP0428849A3 (en) * | 1989-09-28 | 1991-07-31 | Hoechst Aktiengesellschaft | Retroviral protease inhibitors |
EP0538396A1 (en) * | 1990-07-06 | 1993-04-28 | Smithkline Beecham Corporation | Inhibitors of retroviral proteases |
DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH518270A (de) * | 1969-03-07 | 1972-01-31 | Hoffmann La Roche | Verfahren zur Herstellung von Nitrosoharnstoffverbindungen |
JPS5135382B2 (pt) * | 1972-08-04 | 1976-10-01 | ||
JPS50128266A (pt) * | 1974-03-26 | 1975-10-09 | ||
JPS5126876A (en) * | 1974-08-08 | 1976-03-05 | Suami T | Shinkina nitorosonyosojudotaino seizohoho |
US4066750A (en) * | 1976-08-02 | 1978-01-03 | Astra Chemical Products Ab | Lactosyl substituted ureides in ruminant feedstuff |
JPS5331664A (en) * | 1976-09-02 | 1978-03-25 | Suami T | Production of novel nitroso urea derivatives |
JPS5395917A (en) * | 1977-02-03 | 1978-08-22 | Tokyo Tanabe Co | Process for preparing nitrosourea derivative of glucopyranose |
US4148921A (en) * | 1977-07-13 | 1979-04-10 | Suami T | Antitumor agents |
-
1977
- 1977-12-29 HU HU77GO1386A patent/HU176101B/hu unknown
-
1978
- 1978-07-11 AT AT500178A patent/AT360045B/de not_active IP Right Cessation
- 1978-07-12 GR GR56762A patent/GR64891B/el unknown
- 1978-07-12 ZA ZA00783980A patent/ZA783980B/xx unknown
- 1978-07-13 SE SE7807804A patent/SE446529B/xx not_active IP Right Cessation
- 1978-07-13 FR FR7820939A patent/FR2415096A1/fr active Granted
- 1978-07-13 FI FI782238A patent/FI69058C/fi not_active IP Right Cessation
- 1978-07-13 CS CS784690A patent/CS201010B2/cs unknown
- 1978-07-13 AU AU38027/78A patent/AU523845B2/en not_active Expired
- 1978-07-13 IL IL55138A patent/IL55138A/xx unknown
- 1978-07-13 GB GB7829687A patent/GB2011382B/en not_active Expired
- 1978-07-14 YU YU1699/78A patent/YU41314B/xx unknown
- 1978-07-14 DK DK317878A patent/DK155047C/da not_active IP Right Cessation
- 1978-07-14 PT PT68301A patent/PT68301A/pt unknown
- 1978-07-14 NL NL7807587A patent/NL7807587A/xx not_active Application Discontinuation
- 1978-07-14 DE DE19782831094 patent/DE2831094A1/de active Granted
- 1978-07-14 CH CH764278A patent/CH639363A5/de not_active IP Right Cessation
- 1978-07-14 NO NO782447A patent/NO149960C/no unknown
- 1978-07-14 IT IT25682/78A patent/IT1097647B/it active
- 1978-07-14 BE BE189274A patent/BE868988A/xx not_active IP Right Cessation
- 1978-07-14 BG BG040404A patent/BG30016A3/xx unknown
- 1978-07-14 DD DD78206731A patent/DD137224A5/xx not_active IP Right Cessation
- 1978-07-15 PL PL1978208436A patent/PL112198B1/pl unknown
- 1978-07-15 ES ES471778A patent/ES471778A1/es not_active Expired
- 1978-07-15 JP JP8569978A patent/JPS5495517A/ja active Granted
- 1978-07-15 RO RO7894680A patent/RO77027A/ro unknown
- 1978-07-17 CA CA307,574A patent/CA1108182A/en not_active Expired
- 1978-07-17 US US05/925,822 patent/US4237273A/en not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU668107B2 (en) | Oxygen substituted derivatives of nucleophile-nitric oxide adducts as nitric oxide donor prodrugs | |
US4097597A (en) | Dibenzo b,e! 1,4!diazepines | |
Murdock et al. | Antitumor agents. II. Bis (guanylhydrazones) of anthracene-9, 10-dicarboxaldehydes | |
EP0315698A1 (en) | Thieno(triazolo)diazepine compounds and medicinal application of the same | |
NL8202626A (nl) | Derivaten van 9-(2-hydroxyethoxymethyl)guanine. | |
US6306849B1 (en) | Selected derivatives of K-252a | |
EP0031128B1 (en) | (e)-5-(2-halogenovinyl)-arabinofuranosyluracil, process for preparation thereof, and uses thereof | |
SK31596A3 (en) | Polar substituted hydrocarbons | |
FI69058C (fi) | Foerfarande foer framstaellning av terapeutiskt anvaendbara bi(nitrosoureido)polyolderivat | |
JPS6026373B2 (ja) | 抗腸瘍剤 | |
CH657856A5 (de) | Mitosanverbindungen. | |
Kohn et al. | Syntheses and spectral properties of substituted imidazolidones and imidazolines | |
JPS62198666A (ja) | 1−ベンジル−2−/n−置換/−カルバモイル−テトラヒドロイソキノリン及びその製造方法 | |
Vedachalam et al. | Facile synthesis and nitration of cis-syn-cis-2, 6-dioxodecahydro-1H, 5H-diimidazo [4, 5-b: 4', 5'-e] pyrazine | |
CA1285567C (en) | Disulfide derivatives of pyrroloindole | |
Schnur et al. | N-(5-fluorobenzothiazol-2-yl)-2-guanidinothiazole-4-carboxamide. A novel, systemically active antitumor agent effective against 3LL Lewis lung carcinoma | |
EP0255028A2 (de) | Neue 1,4-Benzodiazepine, ihre Herstellung und Verwendung als PAF Antagonisten | |
US5049637A (en) | 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino-[1,2-a]azepino derivatives and 10-aza, 10-oxa and 10-thia analogues | |
CA2120395A1 (en) | Thiazolopyrimidine derivatives | |
Kumar et al. | Syntheses and anthelmintic activity of alkyl 5 (6)-(substituted carbamoyl)-and 5 (6)-(disubstituted carbamoyl) benzimidazole-2-carbamates and related compounds | |
Tam et al. | Synthesis of C-Nucleosides. 17. s-Triazolo [4, 3-a] pyrazines | |
Johnson et al. | Polyfunctional aliphatic compounds VI. The cyclization of dinitriles to benzazepines | |
US6124351A (en) | Amino acid derivatives having a nitric oxide synthase inhibiting action | |
JPS63264580A (ja) | 3−(2−ハロアルキル)−1,4−オキサチインおよび2−(2−ハロアルキル)−1,4−ジチイン | |
US4567256A (en) | Amidine process |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed |
Owner name: RICHTER GEDEON VEGYESZETI GYAR R.T. |