FI67024C - ANORDNING FOER SUBKUTAN DOSERING AV LAEKEMEDEL - Google Patents

Description

67024

This invention relates to an apparatus for administering a drug or other substance by needle to or under the skin of a patient. For the device, the medicine is delivered from the medicine container 5 by means of a peristaltic pump through a hose attached to one end of the medicine container to the needle. The apparatus is suitable for use, for example, in the administration of insulin. The equipment can also be used to dispense a drug or reagent.

A previously filled syringe filled with insulin is commonly used in previously known corresponding insulin pumps. A catheter with a needle extension is removably attached to this syringe. Most commonly, the drug is dispensed from such syringes by mechanically pushing the plunger 15 into the reservoir and this plunger pushes the desired amount of insulin or other substance from the reservoir into the tubing and through its extension needle, e.g., into the skin.

GB 2 077 HO discloses an insulin infusion device in which all the insulin to be dispensed is in a tube placed on the inner circumference of a circular cylindrical housing. The tube is pressed tightly against a roller rotating against the inner circumference, which, as it moves, forces the insulin from the tube into the needle. The other end of the hose is open or equipped with a valve. The main disadvantage of this device is that the patient himself has to fill the hose from a separate insulin ampoule on a daily basis.

The apparatus of the present invention includes a cylindrical drug reservoir, a tubing with injection needles connected to one end thereof, and a peristaltic pump 30 acting on the tubing for transferring medication from the reservoir to the needle. The tank is closed with a plug that can slide inside the tank due to the vacuum caused by the pump.

The container according to the invention is intended for single use as such. It can also be used 35 more times if needed. As a whole, it can be sterilized when it is filled with either a drug, reagent or other solution or before it is filled.

2 67024

When the hose pump pumps insulin into the skin, for example, the stopper follows as the reservoir empties with the liquid so that there is no free air between the liquid and the cap. This has the following advantages: 5 1. First, air never enters the hose from the tank, which is dangerous when pumped into the skin or other parts of the body.

2. This is particularly advantageous in that the insulin cannot so-called loosen in the container and thus be contaminated. Namely, it is known that, for example, shaking the insulin causes some degree of contamination of the insulin and a decrease in its potency, for example in such a way that it may crystallize, in a way. Namely, it is known that shaking insulin, for example, causes some degree of insulin contamination and a decrease in its potency, for example so that it may crystallize.

The tank can be conveniently attached to the pump and after emptying can be removed from the pump, disposed of and replaced with a similar tank. Most usually, this container can be used, for example, in connection with an insulin pump for three to five days, so that the size of the container is such that 100 to 200 units of insulin can be suitably placed in it.

In a particularly preferred embodiment, the container, the hose and the needle are one fixed piece. When a liquid, e.g., insulin, has been depleted from the reservoir, the reservoir with tubing and needles is removed from the pump and discarded and replaced with a new reservoir with a fixed stopper for the fluid, tubing, and needle.

The invention and its details will be described in more detail below with reference to the accompanying drawing, in which Figure 1 shows a medicament container 35 with hoses and needles of a device according to the invention, Figure 2 schematically shows a device according to the invention and Figure 3 shows a detail of a hose pump.

5,67024

The medicament container according to the invention has a container part 1, the other end of which is extended by a resilient hose 2. The connection 13 between the hose 2 and the container 1 is fixed and the hose cannot be removed from the container. This increases security. The connection point between the container 1 and the hose 2 can be obtained, for example, by gluing, ultrasonic welding or another similar procedure. In most cases, it is preferred that the container be, for example, injection molded from a hard-sided plastic raw material, while the hose is a resilient material, yet has a good preservation of its Kaliber.

The other end of the tank part 1 is closed by a plug 3, which can slide freely in the tank, but not 15 leaks. For this reason, the plug is made of a slippery and somewhat resilient material. The slipperiness of the plug is increased by reducing the contact area of the plug with the inner wall of the container by having a special sealing ring 4 at the bottom of the plug and a guide ring 5 at the top of the plug which keeps the plug precisely in the longitudinal axis of the container. In this case, the part 12 between the rings 4 and 5 is detached from the inner wall of the container.

The hose 2 terminates in a needle 6 which can be inserted into or under the skin. At the junction of the needle 6 and the hose 2 there is a support 7, 25 by means of which the needle and the hose can be anchored to the skin, for example with a patch.

When using the medicament container according to the invention, it is fitted, for example, as shown in Fig. 2, to a hose pump 8 known per se, i.e. to a peristaltic pump-30 tree, so that the hose 2 passes through the pump.

Figure 3 shows in more detail a detail of a hose pump. The pump has a rotating disk 9 with rollers 10 around its circumference. towards.