FI66864C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrido(1,2-a)pyrimidinderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrido(1,2-a)pyrimidinderivat Download PDF

Info

Publication number: FI66864C
Authority: FI; Finland
Prior art keywords: ethyl; oxo; pyrido; pyrimidine; methyl
Prior art date: 1977-08-19

Application number

FI782527A

Other languages

English (en)

Finnish (fi)

Other versions

FI782527A (fi

FI66864B (fi

Inventor

Jozsef Knoll

Zoltan Meszaros

Istvan Hermecz

Ferenc Fueloep

Gabor Bernath

Sandor Virag

Gabor Nagy

Peter Szentmiklosi

Original Assignee

Chinoin Gyogyszer Es Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-08-19

Filing date

1978-08-18

Publication date

1984-12-10

1978-08-18 Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet

1979-02-20 Publication of FI782527A publication Critical patent/FI782527A/fi

1984-08-31 Application granted granted Critical

1984-08-31 Publication of FI66864B publication Critical patent/FI66864B/fi

1984-12-10 Publication of FI66864C publication Critical patent/FI66864C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Pain & Pain Management (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI782527A 1977-08-19 1978-08-18 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrido(1,2-a)pyrimidinderivat FI66864C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU77CI1765A HU178910B (en)	1977-08-19	1977-08-19	Process for preparing 2,3-disubstituted-4-oxo-4h-pyrido/1,2-a/-pyrimidines
HUCI001765		1977-08-19

Publications (3)

Publication Number	Publication Date
FI782527A FI782527A (fi)	1979-02-20
FI66864B FI66864B (fi)	1984-08-31
FI66864C true FI66864C (fi)	1984-12-10

Family

ID=10994667

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI782527A FI66864C (fi)	1977-08-19	1978-08-18	Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-oxo-4h-pyrido(1,2-a)pyrimidinderivat

Country Status (22)

Country	Link
US (2)	US4219649A (xx)
JP (1)	JPS5448795A (xx)
AT (1)	AT368156B (xx)
AU (1)	AU518364B2 (xx)
BE (1)	BE869832A (xx)
CA (1)	CA1152989A (xx)
CH (1)	CH637541A5 (xx)
CS (1)	CS238901B1 (xx)
DD (1)	DD138320A5 (xx)
DE (1)	DE2835004A1 (xx)
DK (1)	DK160045C (xx)
ES (1)	ES473181A1 (xx)
FI (1)	FI66864C (xx)
FR (1)	FR2416892A1 (xx)
GB (1)	GB2006187B (xx)
GR (1)	GR64913B (xx)
HU (1)	HU178910B (xx)
IL (1)	IL55338A (xx)
NL (1)	NL7808570A (xx)
SE (1)	SE435383B (xx)
SU (1)	SU906378A3 (xx)
YU (1)	YU40985B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU179143B (en) *	1977-12-29	1982-08-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing 9-hydroxy-groops-containing 6,7-dihydro-pyrido-square bracket-1,2-a-square bracket closed-pyrimidin derivatives and esters thereof
HU180701B (en) *	1977-12-29	1983-04-29	Chinoin Gyogyszer Es Vegyeszet	Process for preparing pyrido-/1,2-a/pyrimidines containing a carboxylic or ester group on the pirimidimering
FR2449689A1 (fr) *	1979-02-20	1980-09-19	Logeais Labor Jacques	Nouveaux derives condenses de pyrrolidine ou de piperidine, leur procede de preparation et leurs applications en therapeutique
US4310526A (en)	1979-05-08	1982-01-12	Farmitalia Carlo Erba S.P.A.	Substituted 6,7-methylene pyrido[1,2-a]pyrimidines useful as anti-allergic and anti-ulcer agents
PL129375B1 (en) *	1980-07-24	1984-05-31	Rhone Poulenc Ind	Process for preparing novel derivatives of 2,3,6,7-tetrahydro-thiazole-/3,2-a/-pyrimidin-5-one
HU183408B (en) *	1981-04-28	1984-05-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing oral ratard pharmaceutical compositions
CA1211111A (en) *	1982-02-15	1986-09-09	Isao Yanagisawa	Process for preparing novel pyrimidone compounds
US5252572A (en) *	1988-02-03	1993-10-12	Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt.	Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
JP2514136B2 (ja) *	1990-05-02	1996-07-10	アボツト・ラボラトリーズ	キノリジノン型化合物
DE10050661A1 (de) *	2000-10-13	2002-04-18	Gruenenthal Gmbh	Substituierte 3,4-Dihydro-pyrimido[1,2-a]pyrimidine und 3,4-Dihydro-pyrazino[1,2-a]pyrimidine
DE10050662A1 (de) *	2000-10-13	2002-04-18	Gruenenthal Gmbh	Substituierte 3,4-Dihydro-pyrido[1,2-a]pyrimidine
DE20202183U1 (de)	2002-02-01	2002-06-06	Kretzschmar, Michael, Dr., 22453 Hamburg	Baukasten
CA2500952C (en) *	2002-10-04	2011-04-26	Prana Biotechnology Limited	Neurologically-active compounds
BRPI0722382A2 (pt) *	2006-04-14	2012-06-05	Prana Biotechnology Ltd	compostos úteis para o tratamento de cáncer
US7955155B2 (en)	2007-07-09	2011-06-07	Mega Brands International	Magnetic and electronic toy construction systems and elements
WO2009063901A1 (ja)	2007-11-13	2009-05-22	The University Of Tokyo	クオラムセンシング阻害剤
CA2727651C (en) *	2008-06-17	2016-04-05	Priscille Brodin	Anti-infective compounds
US10287285B2 (en)	2014-12-02	2019-05-14	Prana Biotechnology Limited	4H-pyrido[1,2-A]pyrimidin-4-one compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT299212B (de) *	1966-11-02	1972-06-12	Chinoin Gyogyszer Es Vegyeszet	Verfahren zur Herstellung von neuen Homopyrimidazol-Derivaten sowie von deren Salzen
HU169230B (xx) *	1972-03-29	1976-10-28
HU168014B (xx) *	1973-03-30	1976-02-28
US4209622A (en) *	1973-03-30	1980-06-24	Chinoin Gygyszer es Vegyeszeti Termekek Gyara Rt.	3-(Ethoxycarbonyl-methyl)-6-methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine
HU168541B (xx) *	1973-11-24	1976-05-28
US4022897A (en) *	1974-03-04	1977-05-10	E. R. Squibb & Sons, Inc.	CNS active compounds
US3898224A (en) *	1974-09-09	1975-08-05	Squibb & Sons Inc	1,6,7,8-Tetrahydro-4-oxo-4H-pyrido {8 1,2-A{9 pyrimidine-9-carboalkoxy compounds
US3935197A (en) *	1975-05-16	1976-01-27	E. R. Squibb & Sons, Inc.	2-Styryl-4H-pyrido(1,2-a)pyrimidin-4-ones

1977
- 1977-08-19 HU HU77CI1765A patent/HU178910B/hu not_active IP Right Cessation
1978
- 1978-08-10 GR GR56973A patent/GR64913B/el unknown
- 1978-08-10 DE DE19782835004 patent/DE2835004A1/de active Granted
- 1978-08-11 IL IL55338A patent/IL55338A/xx unknown
- 1978-08-11 AT AT0585278A patent/AT368156B/de not_active IP Right Cessation
- 1978-08-17 YU YU1966/78A patent/YU40985B/xx unknown
- 1978-08-17 FR FR7823980A patent/FR2416892A1/fr active Granted
- 1978-08-17 US US05/934,801 patent/US4219649A/en not_active Expired - Lifetime
- 1978-08-17 AU AU39009/78A patent/AU518364B2/en not_active Expired
- 1978-08-17 DD DD78207349A patent/DD138320A5/xx not_active IP Right Cessation
- 1978-08-18 FI FI782527A patent/FI66864C/fi not_active IP Right Cessation
- 1978-08-18 SE SE7808770A patent/SE435383B/sv not_active IP Right Cessation
- 1978-08-18 DK DK367478A patent/DK160045C/da not_active IP Right Cessation
- 1978-08-18 GB GB7833924A patent/GB2006187B/en not_active Expired
- 1978-08-18 BE BE189954A patent/BE869832A/xx not_active IP Right Cessation
- 1978-08-18 JP JP10085278A patent/JPS5448795A/ja active Granted
- 1978-08-18 SU SU782652353A patent/SU906378A3/ru active
- 1978-08-18 NL NL7808570A patent/NL7808570A/xx not_active Application Discontinuation
- 1978-08-18 CH CH881578A patent/CH637541A5/de not_active IP Right Cessation
- 1978-08-18 CS CS785417A patent/CS238901B1/cs unknown
- 1978-08-18 CA CA000309620A patent/CA1152989A/en not_active Expired
- 1978-08-19 ES ES473181A patent/ES473181A1/es not_active Expired
1980
- 1980-03-14 US US06/130,371 patent/US4291036A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
SU906378A3 (ru)	1982-02-15
BE869832A (fr)	1978-12-18
CS238901B1 (en)	1985-12-16
IL55338A0 (en)	1978-10-31
AU3900978A (en)	1980-02-21
DK160045C (da)	1991-06-10
FI782527A (fi)	1979-02-20
JPS5448795A (en)	1979-04-17
CS541778A1 (en)	1985-05-15
ES473181A1 (es)	1979-04-01
NL7808570A (nl)	1979-02-21
CH637541A5 (de)	1983-08-15
FR2416892A1 (fr)	1979-09-07
GR64913B (en)	1980-06-09
YU196678A (en)	1983-10-31
FR2416892B1 (xx)	1983-11-18
FI66864B (fi)	1984-08-31
GB2006187A (en)	1979-05-02
DK367478A (da)	1979-02-20
SE7808770L (sv)	1979-02-20
CA1152989A (en)	1983-08-30
JPS626554B2 (xx)	1987-02-12
DE2835004C2 (xx)	1989-06-29
HU178910B (en)	1982-07-28
DD138320A5 (de)	1979-10-24
ATA585278A (de)	1982-01-15
US4219649A (en)	1980-08-26
US4291036A (en)	1981-09-22
SE435383B (sv)	1984-09-24
DE2835004A1 (de)	1979-03-01
AU518364B2 (en)	1981-09-24
GB2006187B (en)	1982-10-06
DK160045B (da)	1991-01-21
YU40985B (en)	1986-10-31
IL55338A (en)	1985-10-31
AT368156B (de)	1982-09-27

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Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: CHINOIN GYOGUSZER ES VEGYESZETI TERMEKEK