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FI62087C - Foerfarande foer framstaellning av 1,2,3,4,10,14b-hexahydrobenso(c)pyrazino(1,2-a)pyridoazepinderivat med antihistamin- oc centralnervstimulerande aktivitet - Google Patents

Foerfarande foer framstaellning av 1,2,3,4,10,14b-hexahydrobenso(c)pyrazino(1,2-a)pyridoazepinderivat med antihistamin- oc centralnervstimulerande aktivitet Download PDF

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Publication number
FI62087C
FI62087C FI760884A FI760884A FI62087C FI 62087 C FI62087 C FI 62087C FI 760884 A FI760884 A FI 760884A FI 760884 A FI760884 A FI 760884A FI 62087 C FI62087 C FI 62087C
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FI
Finland
Prior art keywords
formula
compound
mixture
group
salt
Prior art date
Application number
FI760884A
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English (en)
Finnish (fi)
Other versions
FI760884A (es
FI62087B (fi
Inventor
Willem Jacob Van Der Burg
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19823518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI62087(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI760884A publication Critical patent/FI760884A/fi
Application granted granted Critical
Publication of FI62087B publication Critical patent/FI62087B/fi
Publication of FI62087C publication Critical patent/FI62087C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI760884A 1975-04-05 1976-04-01 Foerfarande foer framstaellning av 1,2,3,4,10,14b-hexahydrobenso(c)pyrazino(1,2-a)pyridoazepinderivat med antihistamin- oc centralnervstimulerande aktivitet FI62087C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NLAANVRAGE7504075,A NL189199C (nl) 1975-04-05 1975-04-05 Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
NL7504075 1975-04-05

Publications (3)

Publication Number Publication Date
FI760884A FI760884A (es) 1976-10-06
FI62087B FI62087B (fi) 1982-07-30
FI62087C true FI62087C (fi) 1982-11-10

Family

ID=19823518

Family Applications (1)

Application Number Title Priority Date Filing Date
FI760884A FI62087C (fi) 1975-04-05 1976-04-01 Foerfarande foer framstaellning av 1,2,3,4,10,14b-hexahydrobenso(c)pyrazino(1,2-a)pyridoazepinderivat med antihistamin- oc centralnervstimulerande aktivitet

Country Status (17)

Country Link
US (1) US4062848A (es)
JP (1) JPS5942678B2 (es)
BE (1) BE840362A (es)
CA (1) CA1076571A (es)
CH (1) CH622261A5 (es)
DE (1) DE2614406A1 (es)
DK (1) DK142498B (es)
ES (2) ES446634A1 (es)
FI (1) FI62087C (es)
FR (1) FR2305986A1 (es)
GB (1) GB1543171A (es)
HU (1) HU179401B (es)
IE (1) IE42969B1 (es)
LU (1) LU74680A1 (es)
NL (2) NL189199C (es)
SE (1) SE422941B (es)
ZA (1) ZA761756B (es)

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KR102540021B1 (ko) 2020-12-02 2023-06-07 (주)유케이케미팜 대량 생산에 적합한 미르타자핀의 제조방법

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Also Published As

Publication number Publication date
DE2614406C2 (es) 1992-02-20
JPS5942678B2 (ja) 1984-10-16
DE2614406A1 (de) 1976-10-14
ZA761756B (en) 1977-03-30
JPS51122099A (en) 1976-10-25
NL189199C (nl) 1993-02-01
CA1076571A (en) 1980-04-29
NL189199B (nl) 1992-09-01
IE42969B1 (en) 1980-11-19
SE422941B (sv) 1982-04-05
FI760884A (es) 1976-10-06
FR2305986A1 (fr) 1976-10-29
HU179401B (en) 1982-10-28
SE7603931L (sv) 1976-10-06
DK142498B (da) 1980-11-10
FR2305986B1 (es) 1980-06-13
ES459348A1 (es) 1978-03-16
CH622261A5 (es) 1981-03-31
AU1236176A (en) 1977-09-29
ES446634A1 (es) 1977-11-01
BE840362A (fr) 1976-10-04
US4062848A (en) 1977-12-13
LU74680A1 (es) 1976-11-11
NL940007I2 (nl) 1994-10-17
NL7504075A (nl) 1976-10-07
DK142676A (es) 1976-10-06
DK142498C (es) 1981-07-06
FI62087B (fi) 1982-07-30
IE42969L (en) 1976-10-05
GB1543171A (en) 1979-03-28
NL940007I1 (nl) 1994-06-01

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