FI61899C - Foerfarande foer framstaellning av antiflogistiska och antitrombotiska 6-substituerad-3-amino-4-fenyl-1h-pyrazolo(3,4-b)pyridiner - Google Patents

Foerfarande foer framstaellning av antiflogistiska och antitrombotiska 6-substituerad-3-amino-4-fenyl-1h-pyrazolo(3,4-b)pyridiner Download PDF

Info

Publication number: FI61899C
Authority: FI; Finland
Prior art keywords: phenyl; nicotinonitrile; chloro; pyrazolo; amino
Prior art date: 1976-09-29

Application number

FI772655A

Other languages

English (en)

Finnish (fi)

Other versions

FI61899B (fi

FI772655A (fi

Inventor

Josef Roch

Erich Mueller

Berthold Narr

Josef Nickl

Walter Haarmann

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-09-29

Filing date

1977-09-07

Publication date

1982-10-11

1977-09-07 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1978-03-30 Publication of FI772655A publication Critical patent/FI772655A/fi

1982-06-30 Application granted granted Critical

1982-06-30 Publication of FI61899B publication Critical patent/FI61899B/fi

1982-10-11 Publication of FI61899C publication Critical patent/FI61899C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI772655A 1976-09-29 1977-09-07 Foerfarande foer framstaellning av antiflogistiska och antitrombotiska 6-substituerad-3-amino-4-fenyl-1h-pyrazolo(3,4-b)pyridiner FI61899C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19762643753 DE2643753A1 (de)	1976-09-29	1976-09-29	Neue 1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine
DE2643753		1976-09-29

Publications (3)

Publication Number	Publication Date
FI772655A FI772655A (fi)	1978-03-30
FI61899B FI61899B (fi)	1982-06-30
FI61899C true FI61899C (fi)	1982-10-11

Family

ID=5989097

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI772655A FI61899C (fi)	1976-09-29	1977-09-07	Foerfarande foer framstaellning av antiflogistiska och antitrombotiska 6-substituerad-3-amino-4-fenyl-1h-pyrazolo(3,4-b)pyridiner

Country Status (21)

Country	Link
US (3)	US4182887A (xx)
JP (1)	JPS5344588A (xx)
AT (1)	AT359064B (xx)
AU (1)	AU513406B2 (xx)
BE (1)	BE859152A (xx)
DE (1)	DE2643753A1 (xx)
DK (1)	DK143183C (xx)
ES (1)	ES462700A1 (xx)
FI (1)	FI61899C (xx)
FR (1)	FR2366290A1 (xx)
GB (1)	GB1552730A (xx)
GR (1)	GR64049B (xx)
IE (1)	IE45700B1 (xx)
IL (1)	IL52997A (xx)
LU (1)	LU78179A1 (xx)
NL (1)	NL7710573A (xx)
NO (1)	NO147913C (xx)
NZ (1)	NZ185292A (xx)
PT (1)	PT67091B (xx)
SE (1)	SE7710873L (xx)
ZA (1)	ZA775784B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2643753A1 (de) *	1976-09-29	1978-04-06	Thomae Gmbh Dr K	Neue 1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine
AR036873A1 (es) *	2001-09-07	2004-10-13	Euro Celtique Sa	Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento
AR037233A1 (es) *	2001-09-07	2004-11-03	Euro Celtique Sa	Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento
WO2005007648A2 (en) *	2003-07-16	2005-01-27	Neurogen Corporation	Biaryl piperazinyl-pyridine analogues
EP1687004A4 (en)	2003-11-10	2009-04-08	Synta Pharmaceuticals Corp	PYRIDINE COMPOUNDS
CA2572645C (en) *	2004-07-06	2011-01-18	F. Hoffmann-La Roche Ag	Process for preparing carboxamide derivatives used as intermediates in the synthesis of nk-1 receptor antagonists
KR100881240B1 (ko)	2004-07-06	2009-02-05	에프. 호프만-라 로슈 아게	Ｎｋ-1 수용체 길항제의 합성에 있어서 중간체로서사용되는 카르복스아미드 피리딘 유도체의 제조 방법
MY145822A (en) *	2004-08-13	2012-04-30	Neurogen Corp	Substituted biaryl piperazinyl-pyridine analogues
US7812166B2 (en)	2004-10-29	2010-10-12	Abbott Laboratories	Kinase inhibitors
DE102004061288A1 (de)	2004-12-14	2006-06-29	Schering Ag	3-Amino-Pyrazolo[3,4b]pyridine als Inhibitoren von Proteintyrosinkinasen, deren Herstellung und Verwendung als Arzneimittel
US7725056B2 (en) *	2006-01-10	2010-05-25	Ricoh Co., Ltd.	Triboelectric charging device and field assisted toner transporter
UA100684C2 (uk)	2007-03-15	2013-01-25	Новартіс Аг	Похідні бензилу та піридинілу як модулятори сигнального шляху hedgehog
US20100041663A1 (en)	2008-07-18	2010-02-18	Novartis Ag	Organic Compounds as Smo Inhibitors
ES2392488T3 (es)	2008-11-20	2012-12-11	Genentech, Inc.	Compuestos inhibidores de PI3K de tipo pirazolopiridina y sus procedimientos de uso
WO2011019780A1 (en)	2009-08-11	2011-02-17	Bristol-Myers Squibb Company	Azaindazoles as btk kinase modulators and use thereof
CN112313232B (zh) *	2018-05-02	2024-03-08	Jw中外制药公司	新型杂环衍生物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2232038A1 (de) *	1972-06-30	1974-01-10	Hoechst Ag	3-amino-1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine, ihre herstellung und verwendung
DE2643753A1 (de) *	1976-09-29	1978-04-06	Thomae Gmbh Dr K	Neue 1h-pyrazolo eckige klammer auf 3,4-b eckige klammer zu pyridine
US4048184A (en) *	1976-11-15	1977-09-13	E. R. Squibb & Sons, Inc.	6-Phenyl-2H-pyrazolo[3,4-b]pyridines

1976
- 1976-09-29 DE DE19762643753 patent/DE2643753A1/de not_active Withdrawn
1977
- 1977-09-07 FI FI772655A patent/FI61899C/fi not_active IP Right Cessation
- 1977-09-19 US US05/834,114 patent/US4182887A/en not_active Expired - Lifetime
- 1977-09-19 AT AT670077A patent/AT359064B/de not_active IP Right Cessation
- 1977-09-22 AU AU29037/77A patent/AU513406B2/en not_active Expired
- 1977-09-26 LU LU78179A patent/LU78179A1/xx unknown
- 1977-09-26 IL IL52997A patent/IL52997A/xx unknown
- 1977-09-27 GR GR54440A patent/GR64049B/el unknown
- 1977-09-28 SE SE7710873A patent/SE7710873L/xx not_active Application Discontinuation
- 1977-09-28 NZ NZ185292A patent/NZ185292A/xx unknown
- 1977-09-28 PT PT67091A patent/PT67091B/pt unknown
- 1977-09-28 ZA ZA00775784A patent/ZA775784B/xx unknown
- 1977-09-28 NL NL7710573A patent/NL7710573A/xx not_active Application Discontinuation
- 1977-09-28 IE IE1988/77A patent/IE45700B1/en unknown
- 1977-09-28 JP JP11657277A patent/JPS5344588A/ja active Pending
- 1977-09-28 GB GB40364/77A patent/GB1552730A/en not_active Expired
- 1977-09-28 NO NO773327A patent/NO147913C/no unknown
- 1977-09-28 DK DK428477A patent/DK143183C/da active
- 1977-09-28 BE BE181275A patent/BE859152A/xx unknown
- 1977-09-28 ES ES462700A patent/ES462700A1/es not_active Expired
- 1977-09-29 FR FR7729322A patent/FR2366290A1/fr active Granted
1979
- 1979-09-13 US US06/075,100 patent/US4260621A/en not_active Expired - Lifetime
- 1979-09-13 US US06/075,493 patent/US4224322A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
IE45700B1 (en)	1982-11-03
ES462700A1 (es)	1978-06-01
FR2366290B1 (xx)	1982-07-09
DK143183B (da)	1981-07-13
IL52997A0 (en)	1977-11-30
JPS5344588A (en)	1978-04-21
GR64049B (en)	1980-01-19
US4224322A (en)	1980-09-23
ZA775784B (en)	1979-06-27
FI61899B (fi)	1982-06-30
NZ185292A (en)	1980-05-08
IL52997A (en)	1980-09-16
BE859152A (fr)	1978-03-28
AU2903777A (en)	1979-03-29
SE7710873L (sv)	1978-03-30
LU78179A1 (xx)	1978-11-03
FR2366290A1 (fr)	1978-04-28
US4260621A (en)	1981-04-07
ATA670077A (de)	1980-03-15
DE2643753A1 (de)	1978-04-06
PT67091A (de)	1977-10-01
DK428477A (da)	1978-03-30
AT359064B (de)	1980-10-27
DK143183C (da)	1981-11-16
NO147913B (no)	1983-03-28
PT67091B (de)	1979-09-12
NO773327L (no)	1978-03-30
NO147913C (no)	1983-07-06
AU513406B2 (en)	1980-11-27
US4182887A (en)	1980-01-08
FI772655A (fi)	1978-03-30
GB1552730A (en)	1979-09-19
NL7710573A (nl)	1978-03-31
IE45700L (en)	1978-03-29

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Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: DR. KARL THOMAE GESELLSCHAFT MIT