FI58136C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 16-deacetoxi-16alfa-acyltiofusidinsyraderivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 16-deacetoxi-16alfa-acyltiofusidinsyraderivat Download PDF

Info

Publication number: FI58136C
Authority: FI; Finland
Prior art keywords: compound; deacetoxy; acid; formula; ether
Prior art date: 1976-07-05

Application number

FI772066A

Other languages

English (en)

Finnish (fi)

Other versions

FI58136B (fi

FI772066A (pt

Inventor

Welf Von Daehne

Poul Roedbroe Rasmussen

Original Assignee

Leo Pharm Prod Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-05

Filing date

1977-07-01

Publication date

1980-12-10

1977-07-01 Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd

1978-01-06 Publication of FI772066A publication Critical patent/FI772066A/fi

1980-08-29 Publication of FI58136B publication Critical patent/FI58136B/fi

1980-12-10 Application granted granted Critical

1980-12-10 Publication of FI58136C publication Critical patent/FI58136C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0027—Azides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

FI772066A 1976-07-05 1977-07-01 Foerfarande foer framstaellning av terapeutiskt anvaendbara 16-deacetoxi-16alfa-acyltiofusidinsyraderivat FI58136C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB27921/76A GB1581335A (en)	1976-07-05	1976-07-05	16-s-acyl derivatives of fusidic acid
GB2792176		1976-07-05

Publications (3)

Publication Number	Publication Date
FI772066A FI772066A (pt)	1978-01-06
FI58136B FI58136B (fi)	1980-08-29
FI58136C true FI58136C (fi)	1980-12-10

Family

ID=10267438

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI772066A FI58136C (fi)	1976-07-05	1977-07-01	Foerfarande foer framstaellning av terapeutiskt anvaendbara 16-deacetoxi-16alfa-acyltiofusidinsyraderivat

Country Status (22)

Country	Link
US (1)	US4119717A (pt)
JP (1)	JPS535152A (pt)
AT (1)	AT354625B (pt)
AU (1)	AU516152B2 (pt)
BE (1)	BE856464A (pt)
CA (1)	CA1100941A (pt)
DE (1)	DE2730196C2 (pt)
DK (1)	DK148390B (pt)
FI (1)	FI58136C (pt)
FR (1)	FR2357574A1 (pt)
GB (1)	GB1581335A (pt)
GR (1)	GR63210B (pt)
IE (1)	IE45217B1 (pt)
IT (1)	IT1083082B (pt)
LU (1)	LU77683A1 (pt)
NL (1)	NL7707221A (pt)
NZ (1)	NZ184408A (pt)
PH (1)	PH14058A (pt)
PT (1)	PT66759B (pt)
SE (1)	SE436752B (pt)
YU (1)	YU165477A (pt)
ZA (1)	ZA773739B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4162259A (en) *	1975-12-03	1979-07-24	Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske fabrik Produktionsaktienselskab)	Fusidic acid derivatives
US4548922A (en) *	1983-06-06	1985-10-22	Beth Israel Hospital	Drug administration
US4959358A (en) *	1983-06-06	1990-09-25	Beth Israel Hospital Assn.	Drug administration
US4746508A (en) *	1983-06-06	1988-05-24	Beth Israel Hospital Assn.	Drug administration
US4994439A (en) *	1989-01-19	1991-02-19	California Biotechnology Inc.	Transmembrane formulations for drug administration
GB9518883D0 (en) *	1995-09-15	1995-11-15	Leo Pharm Prod Ltd	Chemical compounds
MY140194A (en) *	2003-07-16	2009-11-30	Leo Pharma As	Novel fusidic acid derivatives
ES2424395T3 (es) *	2006-09-19	2013-10-01	Abbott Products Gmbh	Derivados de estratrieno y sus usos como inhibidores de la 17-beta-hidroxiesteroide-deshidrogenasa
PT106679B (pt)	2012-11-27	2015-03-25	Hovione Farmaciencia Sa	Formulações tópicas de tetraciclinas, sua preparação e usos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1490852A (en) *	1974-09-12	1977-11-02	Leo Pharm Prod Ltd	Fusidic acid derivatives
US4060606A (en) *	1975-06-25	1977-11-29	Leo Pharmaceutical Products Ltd. A/S	16-Ethers of fusidic acid derivatives
GR60362B (en) *	1975-06-25	1978-05-19	Leo Pharm Prod Ltd	Preparation process of new 16-ethers of fusidic acid derivatives

1976
- 1976-07-05 GB GB27921/76A patent/GB1581335A/en not_active Expired
1977
- 1977-06-14 US US05/806,376 patent/US4119717A/en not_active Expired - Lifetime
- 1977-06-14 IE IE1209/77A patent/IE45217B1/en unknown
- 1977-06-16 NZ NZ184408A patent/NZ184408A/xx unknown
- 1977-06-22 ZA ZA00773739A patent/ZA773739B/xx unknown
- 1977-06-24 AU AU26438/77A patent/AU516152B2/en not_active Expired
- 1977-06-28 AT AT455777A patent/AT354625B/de not_active IP Right Cessation
- 1977-06-29 NL NL7707221A patent/NL7707221A/xx not_active Application Discontinuation
- 1977-07-01 FI FI772066A patent/FI58136C/fi not_active IP Right Cessation
- 1977-07-01 DK DK294177AA patent/DK148390B/da unknown
- 1977-07-04 GR GR53871A patent/GR63210B/el unknown
- 1977-07-04 DE DE2730196A patent/DE2730196C2/de not_active Expired
- 1977-07-04 BE BE179074A patent/BE856464A/xx not_active IP Right Cessation
- 1977-07-04 JP JP7976377A patent/JPS535152A/ja active Granted
- 1977-07-04 SE SE7707749A patent/SE436752B/xx unknown
- 1977-07-04 IT IT68550/77A patent/IT1083082B/it active
- 1977-07-04 LU LU77683A patent/LU77683A1/xx unknown
- 1977-07-04 PT PT66759A patent/PT66759B/pt unknown
- 1977-07-04 FR FR7720523A patent/FR2357574A1/fr active Granted
- 1977-07-04 CA CA281,930A patent/CA1100941A/en not_active Expired
- 1977-07-05 YU YU01654/77A patent/YU165477A/xx unknown
- 1977-07-05 PH PH19958A patent/PH14058A/en unknown

Also Published As

Publication number	Publication date
ATA455777A (de)	1979-06-15
DE2730196C2 (de)	1987-03-05
SE7707749L (sv)	1978-01-06
YU165477A (en)	1982-06-30
DE2730196A1 (de)	1978-01-19
IT1083082B (it)	1985-05-21
FR2357574B1 (pt)	1979-07-20
GR63210B (en)	1979-10-08
ZA773739B (en)	1978-05-30
IE45217B1 (en)	1982-07-14
JPS535152A (en)	1978-01-18
FI58136B (fi)	1980-08-29
AU2643877A (en)	1979-01-04
LU77683A1 (pt)	1978-01-31
AT354625B (de)	1979-01-25
AU516152B2 (en)	1981-05-21
DK148390B (da)	1985-06-24
NL7707221A (nl)	1978-01-09
BE856464A (fr)	1978-01-04
FR2357574A1 (fr)	1978-02-03
JPS6238360B2 (pt)	1987-08-17
GB1581335A (en)	1980-12-10
PT66759B (en)	1978-12-14
IE45217L (en)	1978-01-05
DK294177A (da)	1978-01-06
CA1100941A (en)	1981-05-12
PH14058A (en)	1980-12-29
NZ184408A (en)	1980-04-28
FI772066A (pt)	1978-01-06
PT66759A (en)	1977-08-01
SE436752B (sv)	1985-01-21
US4119717A (en)	1978-10-10

Publication	Publication Date	Title
FI58136C (fi)	1980-12-10	Foerfarande foer framstaellning av terapeutiskt anvaendbara 16-deacetoxi-16alfa-acyltiofusidinsyraderivat
IE55401B1 (en)	1990-09-12	1-,and 1,1-disubstituted-6-substituted-2-carbamimidoyl-1-carbadethiapen-2-em-3-carboxylic acids,a process for preparing and an antibiotic composition containing the same
KR840000081B1 (ko)	1984-02-08	세푸록심 에스테르의 제조방법
DK170443B1 (da)	1995-09-04	Optisk aktive 5R,6S-6-(1R-hydroxyethyl)-2-(cis-1-oxo-3-thiolanylthio)-2-penem-3-carboxylsyreforbindelser samt mellemprodukter ved deres fremstilling
KR100337053B1 (ko)	2002-11-07	티올화합물
CN111560005B (zh)	2022-02-18	一种2-噻吩乙酰氯的制备方法
CN103030608B (zh)	2014-12-17	一种n-(5-脱氢枞基-[1，3,4]噻二唑-2-基）-芳酰胺衍生物、其制备方法及其应用
JPS61158976A (ja)	1986-07-18	ベンゾフランおよびベンゾチオフエン誘導体
Adam et al.	1983	Sulfoxides of penicillanates with non classical substituents in the 6-position
Mereyala et al.	1994	Synthesis of conduritols A,(+)-C and (–)-C from D-galactose
NO833415L (no)	1983-07-12	Fremgangsmaate for fremstilling av 6-aminoalkylpenicillansyre-1,1-dioksyder
JPH0134994B2 (pt)	1989-07-21
CN101316814B (zh)	2012-07-18	采用光反应的维生素d衍生物的制法
JPH05504337A (ja)	1993-07-08	新規な化合物
CA1221371A (en)	1987-05-05	Intermediates and process for preparing (s)-3- acylamino-4-substituted-2-azetidinones
JP2620846B2 (ja)	1997-06-18	１−ブテニルスルフィド誘導体およびその製造法
DK155671B (da)	1989-05-01	7-alfa-alkoxy-7-beta-benzylidenamino-3-cephem-4-carboxylater til anvendelse som mellemprodukter ved fremstilling af 7-alfa-alkoxycephalosporiner og fremgangsmaade til fremstilling af carboxylaterne
EP0003892A1 (en)	1979-09-05	Beta-lactam compounds, processes for their production, compositions containing them and intermediates of use in their preparation
EP0478803B1 (en)	1996-07-10	Process for producing (S)-gamma-acyloxy-methyl-alpha-beta-butenolide
JPH0552835B2 (pt)	1993-08-06
JPH1121267A (ja)	1999-01-26	（−）−シキミ酸又はその前駆体の製造方法
NO862518L (no)	1986-12-29	Nye forbindelser.
WO2018188763A1 (en)	2018-10-18	New process for the synthesis of firocoxib
JPH0236586B2 (ja)	1990-08-17	22haroo22shikuropentenonrui
JPS59152387A (ja)	1984-08-31	新規ペネム化合物

Legal Events

Date	Code	Title	Description
2004-08-31	MM	Patent lapsed	Owner name: LEO PHARMACEUTICAL PRODUCTS LTD A/S (LOEVENS KEMIS