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FI110324B - Nya polysacharider och framställningen därav - Google Patents

Nya polysacharider och framställningen därav Download PDF

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Publication number
FI110324B
FI110324B FI954926A FI954926A FI110324B FI 110324 B FI110324 B FI 110324B FI 954926 A FI954926 A FI 954926A FI 954926 A FI954926 A FI 954926A FI 110324 B FI110324 B FI 110324B
Authority
FI
Finland
Prior art keywords
reaction
polysaccharide
plant cell
cell tissue
sulfuric acid
Prior art date
Application number
FI954926A
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English (en)
Finnish (fi)
Other versions
FI954926A (sv
FI954926A0 (sv
Inventor
Kenichi Kosuna
Original Assignee
Amino Up Chemical Co Ltd
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Publication date
Application filed by Amino Up Chemical Co Ltd filed Critical Amino Up Chemical Co Ltd
Publication of FI954926A0 publication Critical patent/FI954926A0/sv
Publication of FI954926A publication Critical patent/FI954926A/sv
Application granted granted Critical
Publication of FI110324B publication Critical patent/FI110324B/sv

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Claims (7)

1. En ny polysackarid, kännetecknad av att den omfattar med (l->4)-bindningar förenade α-D-glukos-5 enheter, och som uppvisar följande formel: ch2oh ch2oh 1U OR OR väri R är en väteatom eller en acetylgrupp i ett förhällande pi cirka 7:3 i nämnda polysackarid, som har 15 följande egenskaper: (1) karaktär: vitt amorft pulver, utan smak eller doft, (2) löslighet: olöslig i alkohol, aceton, hexan, benzen, etylacetat, tetraklormetan, kloroform och eter, och löslig i vatten, formamid och dimetylsulfoxid. 20 (3) pH av vattenlösning: neutral, (4) sockerkomponent: endast glukos, (5) molekylvikt: 500 - 10.000, (6) specifik optisk vridning: [a]o(24 °C) = +112° - +116°, ·.· : (7) färgreaktion: positiv antron-svavelsyrareaktion, ,,]·* 25 fenol-svavelsyrareaktion och kromotropisk syra-svavelsyra- reaktion, och negativ biuretreaktion, Lowry-Folin- reaktion, Elson-Morgan-reaktion och jodreaktion, (8) smältpunkt: uppvisar ingen tydlig smältpunkt, .·. : (9) IR-spektrum: absorption specifik för acetylgrupper, • * * .···. 30 och "* (10) 13C-NMR-spektrum: uppvisar signaler, som är ·.*.* karakteristiska för a-l,4-glukan och acetylgrupper. * I • · • * · » * · 1103?/· 16
2. Polysackarid enligt patentkrav 1, kanne- tecknad av att den extraheras och isoleras frän ett odlingsmedium, där en mikro-organism tillhörande släktet Basidiomycetes odlas i närvaro av växtcellvävnad som 5 rämaterial.
3. Polysackarid enligt patentkrav 2, kanne- tecknad av att den nämnda växtcellvävnaden bestär av en eller flera växtfibrer valda ur gruppen omfattande 10 kli, rissträ, riskli, bagass, sägspän och sojabönsrester.
4. Förfarande för framställning av en polysackarid, kännetecknat av att förfarandet omfattar följande steg: 15 en mikro-organism tillhörande släktet Basidiomycetes odlas i ett flytande odlingsmedium da växtcellvävnad används som rämaterial, och en polysackarid enligt patentkrav 1 extraheras och isoleras. 20
5. Förfarande enligt patentkrav 4, kännetecknat . av att den nämnda mikro-organismen som tillhör släktet • · ;·[ Basidiomycetes är Lentinus edodes, Agaricus bisporus, IM • Grifola frondosa, Pholiota nameko, Pleurotus ostreatus, *.* ’ Flammulina velutipes, Ganoderma lucidum, Auricularia 25 auricula, Ganoderma applanatum, Coriolus versicolor, Gri- • · • t: j fola umbellata, Schizophyllum commune eller Volvariella : ‘: volvaceae.
: 6. Förfarande enligt patentkrav 4, kännetecknat ,···. 30 av att den nämnda växtcellvävnadsrävaran utgörs av en eller flera växtfibrer omfattande kli, rissträ, riskli, • · * * * o bagass, sagspän och sojabönsrester. » t · 17 1 10324
7. Förfarande enligt patentkrav 6, kännetecknat av att som nämnd växtcellvävnadsravara används ett hetvattenextrakt av en eller flera växtfibrer. • · > » · • 1 < » I » · • t 1 t » · t » · I t * I I I • · • · 1 · 1 1
FI954926A 1995-03-24 1995-10-16 Nya polysacharider och framställningen därav FI110324B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP09004295A JP3651697B2 (ja) 1995-03-24 1995-03-24 新規多糖体物質
JP9004295 1995-03-24

Publications (3)

Publication Number Publication Date
FI954926A0 FI954926A0 (sv) 1995-10-16
FI954926A FI954926A (sv) 1996-09-25
FI110324B true FI110324B (sv) 2002-12-31

Family

ID=13987595

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954926A FI110324B (sv) 1995-03-24 1995-10-16 Nya polysacharider och framställningen därav

Country Status (7)

Country Link
US (1) US5756318A (sv)
EP (1) EP0733647B1 (sv)
JP (1) JP3651697B2 (sv)
KR (1) KR100290044B1 (sv)
DE (1) DE69514498T2 (sv)
FI (1) FI110324B (sv)
MY (1) MY118869A (sv)

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TW358121B (en) * 1995-12-25 1999-05-11 Hitoshi Nagaoka Method for extracting useful substance from culture medium containing mycelium
DE19729273C2 (de) * 1997-07-09 2000-08-17 Aventis Res & Tech Gmbh & Co Thermoplastische Mischung auf 1,4-alpha-D-Polyglucanbasis, Verfahren zu deren Herstellung und Verwendung
KR100362974B1 (ko) * 1997-10-14 2002-11-30 츄가이 세이야꾸 가부시키가이샤 림프구계 종양에 대한 항체의 증진제
US5997875A (en) * 1998-03-27 1999-12-07 Zhou; James H. Herbal composition and treatment methods
CN1370076A (zh) * 1999-08-23 2002-09-18 中外制药株式会社 Hm1.24抗原的表达增强剂
EP1203822A1 (en) * 2000-11-02 2002-05-08 Societe Des Produits Nestle S.A. Extracellular polysaccharide from Gluconacetobacter spp
EP1364657B1 (en) * 2001-02-07 2016-12-28 Chugai Seiyaku Kabushiki Kaisha Remedies for myelocytic leukemia
JP4932128B2 (ja) 2001-02-08 2012-05-16 株式会社アミノアップ化学 生理活性作用を有する新規物質、その製造方法及び用途
KR100442149B1 (ko) * 2001-03-20 2004-07-27 학교법인 동서학원 보리배지 및 이를 이용하여 시조필륨 코뮨으로부터베타-글루칸을 생산하는 방법
US6838096B2 (en) * 2001-06-20 2005-01-04 Taipei Veterans General Hospital Black soybean polysaccharides
NO20014256D0 (no) 2001-09-03 2001-09-03 Bjoern Kristiansen Fremstilling av immunstimulerende forbindelse
US7048932B2 (en) * 2002-05-22 2006-05-23 The Chinese University Of Hong Kong Preparation and standardization of immunomodulatory peptide-linked glucans with verifiable oral absorbability from coriolus versicolor
CN100355876C (zh) * 2003-05-01 2007-12-19 真菌学技术株式会社 担子菌、担子菌提取组合物、保健食品和免疫强化剂
US6975892B2 (en) 2003-10-21 2005-12-13 Oculir, Inc. Methods for non-invasive analyte measurement from the conjunctiva
US6958039B2 (en) * 2003-05-02 2005-10-25 Oculir, Inc. Method and instruments for non-invasive analyte measurement
US6968222B2 (en) * 2003-05-02 2005-11-22 Oculir, Inc. Methods and device for non-invasive analyte measurement
US20060224057A1 (en) * 2003-10-21 2006-10-05 Oculir, Inc. Methods for non-invasive analyte measurement
US20060258919A1 (en) * 2004-04-14 2006-11-16 Oculir, Inc. Non-Invasive Analyte Measurement Device for Measuring Tears and Other Ocular Elements Using Electromagnetic Radiation and Method of Using the Same
US20080009688A1 (en) * 2004-04-14 2008-01-10 Oculir, Inc. Methods for non-invasive analyte measurement
US7514085B2 (en) * 2004-07-16 2009-04-07 Medimush A/S Immune modulating compounds from fungi
EP1774012A2 (en) * 2004-07-16 2007-04-18 Medimush A/S Immune modulating compounds from fungi
WO2006119774A1 (en) * 2005-05-13 2006-11-16 Medimush As Feed or food products comprising fungal material
EP1896600A2 (en) * 2005-06-15 2008-03-12 Medimush A/S Anti-cancer combination treatment and kit-of-part
WO2006133708A1 (en) * 2005-06-15 2006-12-21 Medimush A/S Bioactive agents produced by submerged cultivation of a basidiomycete cell
KR100673051B1 (ko) * 2005-07-29 2007-01-22 양병근 면역 증강 활성을 갖는 맛 버섯 균사체 액체배양물로부터분리한 세포내 생체고분자
ES2341163B1 (es) 2008-09-26 2011-05-11 Bioiberica, S.A. Composiciones inmunoestimulantes.
WO2014077340A1 (ja) * 2012-11-14 2014-05-22 独立行政法人産業技術総合研究所 β－１，３－グルカン誘導体、及びβ－１，３－グルカン誘導体の製造方法
KR101802142B1 (ko) * 2015-11-30 2017-11-29 (주)에스티알바이오텍 대두생물전환물을 함유하는 면역증강용, 당뇨개선용, 고지혈증 개선 또는 간 보호용 조성물
KR101886038B1 (ko) * 2017-06-20 2018-08-07 (주)에스티알바이오텍 대두생물전환물을 함유하는 면역증강용, 당뇨개선용, 고지혈증 개선 또는 간 보호용 조성물
CN107698695B (zh) * 2017-09-12 2021-06-01 广州中医药大学第二附属医院 具有免疫调节活性的均一多糖及其制备方法
CN109609525A (zh) * 2019-01-10 2019-04-12 江苏大学 灰树花葡聚糖合成酶、其编码基因及应用
CN112094878A (zh) * 2020-08-18 2020-12-18 周银根 一种二步酶提取香菇多糖的方法、香菇多糖提取物及其应用

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Also Published As

Publication number Publication date
FI954926A (sv) 1996-09-25
KR100290044B1 (ko) 2001-05-15
DE69514498T2 (de) 2000-08-03
EP0733647A3 (en) 1997-05-02
US5756318A (en) 1998-05-26
DE69514498D1 (de) 2000-02-17
MY118869A (en) 2005-02-28
EP0733647A2 (en) 1996-09-25
EP0733647B1 (en) 2000-01-12
FI954926A0 (sv) 1995-10-16
JPH08259602A (ja) 1996-10-08
JP3651697B2 (ja) 2005-05-25
KR960034221A (ko) 1996-10-22

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