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FI109797B - Menetelmä 10-desasetyylibakkatiini III:n valmistamiseksi käyttäen marjakuusta raaka-aineena - Google Patents

Menetelmä 10-desasetyylibakkatiini III:n valmistamiseksi käyttäen marjakuusta raaka-aineena Download PDF

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Publication number
FI109797B
FI109797B FI951590A FI951590A FI109797B FI 109797 B FI109797 B FI 109797B FI 951590 A FI951590 A FI 951590A FI 951590 A FI951590 A FI 951590A FI 109797 B FI109797 B FI 109797B
Authority
FI
Finland
Prior art keywords
taxus
iii
methyl
eller
acetate
Prior art date
Application number
FI951590A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI951590A0 (fi
FI951590L (fi
Inventor
Rodolphe Margraff
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI951590A0 publication Critical patent/FI951590A0/fi
Publication of FI951590L publication Critical patent/FI951590L/fi
Application granted granted Critical
Publication of FI109797B publication Critical patent/FI109797B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI951590A 1992-10-05 1995-04-04 Menetelmä 10-desasetyylibakkatiini III:n valmistamiseksi käyttäen marjakuusta raaka-aineena FI109797B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9211745 1992-10-05
FR9211745A FR2696462B1 (fr) 1992-10-05 1992-10-05 Procédé d'obtention de la désacétyl-10 baccatine III.
FR9300971 1993-10-04
PCT/FR1993/000971 WO1994007881A1 (fr) 1992-10-05 1993-10-04 Procede d'obtention de la desacetyl-10 baccatine iii

Publications (3)

Publication Number Publication Date
FI951590A0 FI951590A0 (fi) 1995-04-04
FI951590L FI951590L (fi) 1995-04-04
FI109797B true FI109797B (fi) 2002-10-15

Family

ID=9434123

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951590A FI109797B (fi) 1992-10-05 1995-04-04 Menetelmä 10-desasetyylibakkatiini III:n valmistamiseksi käyttäen marjakuusta raaka-aineena

Country Status (30)

Country Link
US (2) US5393896A (zh)
EP (1) EP0663909B1 (zh)
JP (1) JP3299753B2 (zh)
KR (1) KR100301238B1 (zh)
CN (1) CN1041310C (zh)
AT (1) ATE147381T1 (zh)
AU (1) AU680440B2 (zh)
CA (2) CA2470124C (zh)
CZ (2) CZ286452B6 (zh)
DE (1) DE69307333T2 (zh)
DK (1) DK0663909T3 (zh)
EE (1) EE03124B1 (zh)
ES (1) ES2095672T3 (zh)
FI (1) FI109797B (zh)
FR (1) FR2696462B1 (zh)
GE (1) GEP19981433B (zh)
GR (1) GR3022229T3 (zh)
HU (1) HU225969B1 (zh)
LT (1) LT3465B (zh)
LV (1) LV10620B (zh)
MX (1) MX9305770A (zh)
NO (1) NO310414B1 (zh)
NZ (1) NZ256449A (zh)
PL (1) PL173993B1 (zh)
RU (1) RU2108330C1 (zh)
SK (1) SK280335B6 (zh)
TW (1) TW404944B (zh)
UA (1) UA40601C2 (zh)
WO (1) WO1994007881A1 (zh)
ZA (1) ZA937312B (zh)

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CN101007173A (zh) 1993-07-19 2007-08-01 血管技术药物公司 抗血管生长组合物及使用方法
FR2714053B1 (fr) * 1993-12-22 1996-03-08 Pf Medicament Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III.
CN1112433A (zh) * 1994-05-24 1995-11-29 郭明 红豆杉属植物提取物及其应用
AU716005B2 (en) 1995-06-07 2000-02-17 Cook Medical Technologies Llc Implantable medical device
FR2736355B1 (fr) * 1995-07-07 1997-11-07 Pf Medicament Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii
US5965752A (en) * 1996-08-23 1999-10-12 Institut National De La Recherche Scientifique Preparative scale isolation and purification of taxanes
DE69812395T2 (de) 1997-08-21 2004-02-05 Florida State University, Tallahassee Verfahren zur synthese von taxanen
US6066748A (en) * 1997-12-17 2000-05-23 Han; Man Woo Process of extracting TAXOL® from taxus cuspidata
CA2317728A1 (en) 1998-01-14 1999-07-22 Bristol-Myers Squibb Company Novel crystalline complexes of baccatin iii with imidazole, 2-methylimidazole or isopropanol
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Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601676B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5380916A (en) 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5279953A (en) * 1992-06-24 1994-01-18 Esca Genetics Corporation In vivo production of taxanes
FR2696463B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
FR2703049B1 (fr) * 1993-03-22 1995-04-21 Rhone Poulenc Rorer Sa Procédé de purification des taxoïdes.

Also Published As

Publication number Publication date
UA40601C2 (uk) 2001-08-15
RU95110662A (ru) 1996-12-27
US5393896A (en) 1995-02-28
ES2095672T3 (es) 1997-02-16
GEP19981433B (en) 1998-10-30
US5736366A (en) 1998-04-07
FI951590A0 (fi) 1995-04-04
CZ84495A3 (en) 1995-09-13
DE69307333D1 (de) 1997-02-20
HUT72678A (en) 1996-05-28
LV10620A (lv) 1995-04-20
NO951281L (no) 1995-04-03
SK43195A3 (en) 1995-08-09
NO310414B1 (no) 2001-07-02
NO951281D0 (no) 1995-04-03
CA2470124C (fr) 2007-08-07
LV10620B (en) 1995-10-20
JP3299753B2 (ja) 2002-07-08
GR3022229T3 (en) 1997-04-30
EP0663909A1 (fr) 1995-07-26
JPH08501791A (ja) 1996-02-27
HU225969B1 (en) 2008-01-28
CA2470124A1 (fr) 1994-04-14
PL308243A1 (en) 1995-07-24
CZ286452B6 (en) 2000-04-12
CA2146248A1 (fr) 1994-04-14
EE03124B1 (et) 1998-10-15
ATE147381T1 (de) 1997-01-15
LTIP1398A (en) 1994-11-25
MX9305770A (es) 1994-05-31
NZ256449A (en) 1996-09-25
KR950703549A (ko) 1995-09-20
ZA937312B (en) 1994-04-25
CN1085552A (zh) 1994-04-20
WO1994007881A1 (fr) 1994-04-14
LT3465B (en) 1995-10-25
SK280335B6 (sk) 1999-12-10
CZ286593B6 (cs) 2000-05-17
KR100301238B1 (ko) 2001-11-22
AU5115493A (en) 1994-04-26
FI951590L (fi) 1995-04-04
AU680440B2 (en) 1997-07-31
HU9500969D0 (en) 1995-06-28
FR2696462A1 (fr) 1994-04-08
CA2146248C (fr) 2006-12-12
DE69307333T2 (de) 1997-04-30
DK0663909T3 (zh) 1997-01-27
FR2696462B1 (fr) 1994-11-25
PL173993B1 (pl) 1998-05-29
TW404944B (en) 2000-09-11
CN1041310C (zh) 1998-12-23
EP0663909B1 (fr) 1997-01-08
RU2108330C1 (ru) 1998-04-10

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