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FI103042B1 - Förfarande för framställning av amlodipinbensensulfonat och en i detta förfarande som mellanprodukt fungerande förening - Google Patents

Förfarande för framställning av amlodipinbensensulfonat och en i detta förfarande som mellanprodukt fungerande förening

Info

Publication number
FI103042B1
FI103042B1 FI934882A FI934882A FI103042B1 FI 103042 B1 FI103042 B1 FI 103042B1 FI 934882 A FI934882 A FI 934882A FI 934882 A FI934882 A FI 934882A FI 103042 B1 FI103042 B1 FI 103042B1
Authority
FI
Finland
Prior art keywords
preparation
amlodipine benzenesulfonate
amlodipine
benzenesulfonate
Prior art date
Application number
FI934882A
Other languages
English (en)
Finnish (fi)
Other versions
FI934882A0 (fi
FI934882A (fi
FI103042B (sv
Inventor
Borut Furlan
Anton Copar
Alenka Jeriha
Original Assignee
Lek Tovarna Farmacevtskih
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Tovarna Farmacevtskih filed Critical Lek Tovarna Farmacevtskih
Publication of FI934882A0 publication Critical patent/FI934882A0/fi
Publication of FI934882A publication Critical patent/FI934882A/fi
Application granted granted Critical
Publication of FI103042B1 publication Critical patent/FI103042B1/sv
Publication of FI103042B publication Critical patent/FI103042B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
FI934882A 1992-11-26 1993-11-04 Förfarande för framställning av amlodipinbensensulfonat och en i detta förfarande som mellanprodukt fungerande förening FI103042B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI9200344A SI9200344B (sl) 1992-11-26 1992-11-26 Postopek za pripravo amlodipin benzensulfonata
SI9200344 1992-11-26

Publications (4)

Publication Number Publication Date
FI934882A0 FI934882A0 (fi) 1993-11-04
FI934882A FI934882A (fi) 1994-05-27
FI103042B1 true FI103042B1 (sv) 1999-04-15
FI103042B FI103042B (sv) 1999-04-15

Family

ID=20431051

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934882A FI103042B (sv) 1992-11-26 1993-11-04 Förfarande för framställning av amlodipinbensensulfonat och en i detta förfarande som mellanprodukt fungerande förening

Country Status (9)

Country Link
EP (1) EP0599220B1 (sv)
CZ (1) CZ283041B6 (sv)
DE (1) DE69304020T2 (sv)
FI (1) FI103042B (sv)
HR (1) HRP931429B1 (sv)
PL (2) PL174647B1 (sv)
RU (1) RU2105759C1 (sv)
SI (1) SI9200344B (sv)
SK (1) SK279353B6 (sv)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221810B1 (hu) * 1997-08-12 2003-01-28 EGIS Gyógyszergyár Rt. Eljárás amlodipin-bezilát előállítására és az eljárás intermedierjei
UA72768C2 (en) * 1999-07-05 2005-04-15 Richter Gedeon Vegyeszet A method for obtaining amilodipine benzenesulphonate
ATE454890T1 (de) * 2001-07-06 2010-01-15 Lek Pharmaceuticals Verfahren zur herstellung hochreines amlodipinbenzolsulfonat
US6680334B2 (en) 2001-08-28 2004-01-20 Pfizer Inc Crystalline material
US6828339B2 (en) * 2001-11-21 2004-12-07 Synthon Bv Amlodipine salt forms and processes for preparing them
SI21233A (sl) * 2002-05-31 2003-12-31 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Kristalni hidratni obliki amlodipin benzensulfonata visoke čistote, postopki za njuno pripravo in uporaba
US6784297B2 (en) 2002-09-04 2004-08-31 Kopran Limited Process for the preparation of anti-ischemic and anti-hypertensive drug amlodipine besylate
EP1407773A1 (en) * 2002-10-08 2004-04-14 Council of Scientific and Industrial Research A process for the preparation of s (-) amlodipine salts
AU2002368531A1 (en) * 2002-12-30 2004-07-22 Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. Isolation of dihydropyridine derivative and preparation salts thereof
RU2326886C2 (ru) 2003-03-28 2008-06-20 Ниссан Кемикал Индастриз, Лтд. Блокатор кальциевых каналов т-типа
WO2007131759A1 (en) * 2006-05-15 2007-11-22 Lek Pharmaceuticals D.D. A process for the preparation of amlodipine benzenesulfonate
LT2824100T (lt) 2008-07-08 2018-05-10 Incyte Holdings Corporation 1,2,5-oksadiazolai, kaip indolamino 2,3-dioksigenazės inhibitoriai
SG171722A1 (en) 2008-12-22 2011-07-28 Pola Chem Ind Inc Melanin production inhibitor
CN102516159B (zh) * 2011-12-15 2013-10-09 扬子江药业集团江苏海慈生物药业有限公司 一种苯磺酸左旋氨氯地平的生产方法
US10034939B2 (en) 2012-10-26 2018-07-31 The University Of Chicago Synergistic combination of immunologic inhibitors for the treatment of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
GB8608335D0 (en) * 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
EP0352863A3 (en) * 1988-07-29 1990-08-22 ZAMBON GROUP S.p.A. 1,4-dihydropyridine dicarboxylic acid derivatives

Also Published As

Publication number Publication date
HRP931429B1 (en) 1997-10-31
PL301080A1 (en) 1994-05-30
SK112593A3 (en) 1994-11-09
SK279353B6 (sk) 1998-10-07
FI934882A0 (fi) 1993-11-04
HRP931429A2 (en) 1995-12-31
RU2105759C1 (ru) 1998-02-27
PL174647B1 (pl) 1998-08-31
CZ283041B6 (cs) 1997-12-17
EP0599220A1 (en) 1994-06-01
PL173645B1 (pl) 1998-04-30
SI9200344A (en) 1994-06-30
DE69304020D1 (de) 1996-09-19
CZ216593A3 (en) 1994-06-15
EP0599220B1 (en) 1996-08-14
SI9200344B (sl) 1998-06-30
FI934882A (fi) 1994-05-27
FI103042B (sv) 1999-04-15
DE69304020T2 (de) 1997-03-06

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH

MM Patent lapsed