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ES8801263A1 - PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 10 L-METOXI-6-METHYLERGOLINE AND ITS ADDITIONAL SALTS OF ACIDS - Google Patents

PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 10 L-METOXI-6-METHYLERGOLINE AND ITS ADDITIONAL SALTS OF ACIDS

Info

Publication number
ES8801263A1
ES8801263A1 ES556358A ES556358A ES8801263A1 ES 8801263 A1 ES8801263 A1 ES 8801263A1 ES 556358 A ES556358 A ES 556358A ES 556358 A ES556358 A ES 556358A ES 8801263 A1 ES8801263 A1 ES 8801263A1
Authority
ES
Spain
Prior art keywords
methylergoline
metoxi
derivatives
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556358A
Other languages
Spanish (es)
Other versions
ES556358A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES556358A0 publication Critical patent/ES556358A0/en
Publication of ES8801263A1 publication Critical patent/ES8801263A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 10A-METOXI-METHYLERGOLINE, OF GENERAL FORMULA (I), AND OF ITS PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS. IT CONSISTS OF EXPOSING 2-HALOGEN-LISERGOL, IN A GENERAL FORMULA (II), IN WHICH X REPRESENTS CHLORINE, BROMINE OR IODINE, IN A METHANOL WITH SULFURIC ACID, TO ULTRAVIOLET RADIATION, TO OBTAIN 2-HALOGEN-LUMILISOL GENERAL FORM (I), IN WHICH R AND R'' MEAN HYDROGEN. OF APPLICATION AS VALUABLE INTERMEDIATE COMPOUNDS FOR THE PRODUCTION OF NICERGOLINE, KNOWN AS A PERIPHERAL VASODILATOR. (Machine-translation by Google Translate, not legally binding)
ES556358A 1985-06-21 1986-06-20 PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 10 L-METOXI-6-METHYLERGOLINE AND ITS ADDITIONAL SALTS OF ACIDS Expired ES8801263A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852446A HU193781B (en) 1985-06-21 1985-06-21 Process for producing 10alpha-methoxy-6-methylergoline derivatives and acid additional salts thereof

Publications (2)

Publication Number Publication Date
ES556358A0 ES556358A0 (en) 1988-01-01
ES8801263A1 true ES8801263A1 (en) 1988-01-01

Family

ID=10959396

Family Applications (1)

Application Number Title Priority Date Filing Date
ES556358A Expired ES8801263A1 (en) 1985-06-21 1986-06-20 PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 10 L-METOXI-6-METHYLERGOLINE AND ITS ADDITIONAL SALTS OF ACIDS

Country Status (14)

Country Link
BE (1) BE904956A (en)
CS (1) CS255876B2 (en)
DD (1) DD246110A5 (en)
DE (1) DE3620487A1 (en)
DK (1) DK291986A (en)
ES (1) ES8801263A1 (en)
FR (1) FR2583755B1 (en)
GB (1) GB2177090B (en)
GR (1) GR861619B (en)
HU (1) HU193781B (en)
IT (1) IT1190135B (en)
LU (1) LU86486A1 (en)
NL (1) NL8601584A (en)
PT (1) PT82807B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
GB9603226D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Heterocyclyl-ergoline derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1094965B (en) * 1978-04-05 1985-08-10 Corvi Mora E LISERGOL DERIVATION PREPARATION PROCEDURE
HU193782B (en) * 1985-06-21 1987-11-30 Richter Gedeon Vegyeszet Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof

Also Published As

Publication number Publication date
GB2177090A (en) 1987-01-14
PT82807A (en) 1986-07-01
NL8601584A (en) 1987-01-16
ES556358A0 (en) 1988-01-01
LU86486A1 (en) 1986-12-02
IT8620854A0 (en) 1986-06-19
FR2583755A1 (en) 1986-12-26
GB8615121D0 (en) 1986-07-23
GR861619B (en) 1986-10-21
DD246110A5 (en) 1987-05-27
DK291986A (en) 1986-12-22
GB2177090B (en) 1989-07-12
FR2583755B1 (en) 1990-06-22
HUT41023A (en) 1987-03-30
PT82807B (en) 1988-04-21
IT8620854A1 (en) 1987-12-19
HU193781B (en) 1987-11-30
IT1190135B (en) 1988-02-10
DE3620487A1 (en) 1987-01-02
BE904956A (en) 1986-12-19
CS255876B2 (en) 1988-03-15
DK291986D0 (en) 1986-06-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303