ES8800981A1 - Un procedimiento para tratar celulas efectoras que tienen receptores de superficie para la region fc de un anticuerpo - Google Patents
Un procedimiento para tratar celulas efectoras que tienen receptores de superficie para la region fc de un anticuerpoInfo
- Publication number
- ES8800981A1 ES8800981A1 ES556684A ES556684A ES8800981A1 ES 8800981 A1 ES8800981 A1 ES 8800981A1 ES 556684 A ES556684 A ES 556684A ES 556684 A ES556684 A ES 556684A ES 8800981 A1 ES8800981 A1 ES 8800981A1
- Authority
- ES
- Spain
- Prior art keywords
- antibody
- region
- surface receptors
- procedure
- treating effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000012636 effector Substances 0.000 abstract 3
- 210000002966 serum Anatomy 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001472 cytotoxic effect Effects 0.000 abstract 1
- 230000001024 immunotherapeutic effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/44—Antibodies bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
METODO DE TRATAMIENTO DE CELULAS EFECTORAS QUE TIENEN RECEPTORES DE SUPERFICIE PARA LA REGION FC DE UN ANTICUERPO. CONSISTE EN LA ACTIVACION DE DICHAS CELULAS EFECTORAS IN VITRO, MEDIANTE TRATAMIENTO CON UN COMPUESTO TAL COMO UNA LINGOQUINA, SUERO ALOGENICO, SUERO XENOGENICO O UNA DE SUS MEZCLAS, PARA AUMENTAR LA ACTIVIDAD CITOTOXICA CELULAR DEPENDIENTE DE ANTICUERPOS DE DICHAS CELULAS EFECTORAS DE 1,25 A 125 VECES EL DE ESTAS CELULAS EN SU ESTADO NATURAL. TIENE APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO INMUNOTERAPEUTICO DE CAPNCER Y TUMORES NO MALIGNOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75009185A | 1985-06-28 | 1985-06-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES556684A0 ES556684A0 (es) | 1987-12-01 |
ES8800981A1 true ES8800981A1 (es) | 1987-12-01 |
Family
ID=25016458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES556684A Expired ES8800981A1 (es) | 1985-06-28 | 1986-06-25 | Un procedimiento para tratar celulas efectoras que tienen receptores de superficie para la region fc de un anticuerpo |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0227809B1 (es) |
JP (1) | JPS62503144A (es) |
CN (1) | CN86104913A (es) |
AT (1) | ATE80802T1 (es) |
AU (1) | AU597265B2 (es) |
CA (1) | CA1341303C (es) |
DE (1) | DE3686811D1 (es) |
DK (1) | DK107787D0 (es) |
ES (1) | ES8800981A1 (es) |
HU (1) | HUT43495A (es) |
IL (1) | IL79260A (es) |
WO (1) | WO1987000054A1 (es) |
ZA (1) | ZA864769B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5192537A (en) * | 1984-03-30 | 1993-03-09 | Cellcor Inc. | Method of treating renal cell carcinoma using activated mononuclear cells, renal tumor antigen and cimetidine |
US4894227A (en) * | 1986-08-01 | 1990-01-16 | Cetus Corporation | Composition of immunotoxins with interleukin-2 |
US4863726A (en) * | 1987-05-29 | 1989-09-05 | Cetus Corporation | Combination therapy using immunotoxins with interleukin-2 |
WO1989005657A1 (en) * | 1987-12-17 | 1989-06-29 | Browning's Clinical Pathology Services Limited | Lymphokine activation of cells for adoptive immunotherapy, e.g. of hiv infection |
US5834441A (en) * | 1993-09-13 | 1998-11-10 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Adeno-associated viral (AAV) liposomes and methods related thereto |
US6652850B1 (en) | 1993-09-13 | 2003-11-25 | Aventis Pharmaceuticals Inc. | Adeno-associated viral liposomes and their use in transfecting dendritic cells to stimulate specific immunity |
WO1999053027A1 (en) * | 1998-04-09 | 1999-10-21 | I.D.M. Immuno-Designed Molecules | Use of monocytes derived cells and antibodies in a synergic way for optimal induction of immunotherapeutic efficiency |
US20020168347A1 (en) * | 1998-04-09 | 2002-11-14 | Jacques Bartholeyns | Use of monocytes derived cells, antigens and antibodies for optimal induction of immunotherapeutic efficiency |
US6868665B2 (en) | 2001-12-21 | 2005-03-22 | General Electric Company | Methods and apparatus for operating gas turbine engines |
US7200538B2 (en) | 2003-01-15 | 2007-04-03 | General Electric Company | Methods and apparatus for modeling gas turbine engines |
-
1986
- 1986-06-25 CA CA000512441A patent/CA1341303C/en not_active Expired - Fee Related
- 1986-06-25 ES ES556684A patent/ES8800981A1/es not_active Expired
- 1986-06-26 ZA ZA864769A patent/ZA864769B/xx unknown
- 1986-06-26 JP JP61503590A patent/JPS62503144A/ja active Pending
- 1986-06-26 HU HU863275A patent/HUT43495A/hu unknown
- 1986-06-26 AU AU61254/86A patent/AU597265B2/en not_active Ceased
- 1986-06-26 AT AT86904562T patent/ATE80802T1/de not_active IP Right Cessation
- 1986-06-26 EP EP86904562A patent/EP0227809B1/en not_active Expired - Lifetime
- 1986-06-26 WO PCT/US1986/001348 patent/WO1987000054A1/en active IP Right Grant
- 1986-06-26 DE DE8686904562T patent/DE3686811D1/de not_active Expired - Lifetime
- 1986-06-27 IL IL79260A patent/IL79260A/xx not_active IP Right Cessation
- 1986-06-28 CN CN198686104913A patent/CN86104913A/zh active Pending
-
1987
- 1987-03-02 DK DK107787A patent/DK107787D0/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN86104913A (zh) | 1987-05-27 |
DE3686811D1 (de) | 1992-10-29 |
EP0227809A4 (en) | 1987-10-19 |
AU6125486A (en) | 1987-01-30 |
ES556684A0 (es) | 1987-12-01 |
IL79260A0 (en) | 1986-09-30 |
DK107787A (da) | 1987-03-02 |
AU597265B2 (en) | 1990-05-31 |
CA1341303C (en) | 2001-10-09 |
HUT43495A (en) | 1987-11-30 |
WO1987000054A1 (en) | 1987-01-15 |
DK107787D0 (da) | 1987-03-02 |
JPS62503144A (ja) | 1987-12-17 |
IL79260A (en) | 1990-11-29 |
ATE80802T1 (de) | 1992-10-15 |
EP0227809B1 (en) | 1992-09-23 |
ZA864769B (en) | 1987-02-25 |
EP0227809A1 (en) | 1987-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted |
Owner name: GARY R. LANDUCCI (TITULAR AL 50%) |