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ES8700933A1 - Un metodo para preparar esterol-liposomas - Google Patents

Un metodo para preparar esterol-liposomas

Info

Publication number
ES8700933A1
ES8700933A1 ES547326A ES547326A ES8700933A1 ES 8700933 A1 ES8700933 A1 ES 8700933A1 ES 547326 A ES547326 A ES 547326A ES 547326 A ES547326 A ES 547326A ES 8700933 A1 ES8700933 A1 ES 8700933A1
Authority
ES
Spain
Prior art keywords
vesicules
sterol
formation
occlude
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547326A
Other languages
English (en)
Other versions
ES547326A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharmaceuticals LLC
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/721,630 external-priority patent/US4721612A/en
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of ES8700933A1 publication Critical patent/ES8700933A1/es
Publication of ES547326A0 publication Critical patent/ES547326A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2984—Microcapsule with fluid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Seal Device For Vehicle (AREA)

Abstract

METODO DE PREPARACION DE LIPOSOMAS DE ESTEROLES. CONSISTE EN AÑADIR A UNA FASE ACUOSA TAMPONADA UNA FORMA DE SAL DE UN DERIVADO DE ACIDO ORGANICO DE UN ESTEROL, QUE FORMA BICAPAS CERRADAS DE MODO QUE SE CONSTITUYEN VESICULAS COMPLETAMENTE CERRADAS; Y AGITAR LA MEZCLA HASTA LA FORMACION DE UNA SUSPENSION DE VESICULAS MULTILAMINARES. LA FORMACION DE VESICULAS SE FACILITA SI EL TAMPON CONTIENE EL ION OPUESTO DE LA SAL EN DISOLUCION. PARA OCLUIR EN LAS VESICULAS DE ESTEROL UN COMPUESTO SOLUBLE EN AGUA, SE AÑADE A LA FASE ACUOSA ANTES DE LA FORMACION DE LAS VESICULAS. SI EL COMPUESTO ES INSOLUBLE EN AGUA, SE AÑADE DESPUES DE LA FORMACION DE LAS VESICULAS. LAS VESICULAS DE ESTEROLES TIENEN APLICACIONES PARA OCLUIR COMPUESTOS ACTIVOS BIOLOGICAMENTE O QUE PUEDEN ADMINISTRARSE IN VIVO.-
ES547326A 1985-04-10 1985-09-26 Un metodo para preparar esterol-liposomas Expired ES8700933A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/721,630 US4721612A (en) 1984-04-12 1985-04-10 Steroidal liposomes
US06/773,429 US4891208A (en) 1985-04-10 1985-09-10 Steroidal liposomes

Publications (2)

Publication Number Publication Date
ES8700933A1 true ES8700933A1 (es) 1986-11-16
ES547326A0 ES547326A0 (es) 1986-11-16

Family

ID=27110456

Family Applications (2)

Application Number Title Priority Date Filing Date
ES547326A Expired ES8700933A1 (es) 1985-04-10 1985-09-26 Un metodo para preparar esterol-liposomas
ES553808A Expired ES8801085A1 (es) 1985-04-10 1986-04-09 Un metodo para preparar una crema antifungica

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES553808A Expired ES8801085A1 (es) 1985-04-10 1986-04-09 Un metodo para preparar una crema antifungica

Country Status (16)

Country Link
US (1) US4891208A (es)
EP (1) EP0222771A4 (es)
JP (1) JPH0798741B2 (es)
KR (1) KR890001882B1 (es)
AU (2) AU596953B2 (es)
CA (1) CA1262334A (es)
DK (1) DK591086A (es)
ES (2) ES8700933A1 (es)
FI (1) FI92463C (es)
HU (1) HU203205B (es)
IE (1) IE66709B1 (es)
IL (1) IL76600A (es)
NO (1) NO173213C (es)
NZ (1) NZ213601A (es)
PT (1) PT81242B (es)
WO (1) WO1986005977A1 (es)

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US5231112A (en) 1984-04-12 1993-07-27 The Liposome Company, Inc. Compositions containing tris salt of cholesterol hemisuccinate and antifungal
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US5736155A (en) * 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
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US5468224A (en) * 1993-11-30 1995-11-21 Souryal; Tarek O. Methods of color coding injectable medications
EP0734250A1 (en) * 1993-12-15 1996-10-02 Micro-Pak, Inc. Lipid vesicles containing avocado oil unsaponifiables
US5716526A (en) * 1994-01-14 1998-02-10 The Liposome Company, Inc. Method of separating materials from liposomes or lipid complexes
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US5670163A (en) * 1994-06-20 1997-09-23 Kv Pharmaceuticals Company Long acting GI and esophageal protectant
US5554379A (en) * 1994-06-20 1996-09-10 Kv Pharmaceutical Company Long acting GI and esophageal protectant
US5672357A (en) * 1994-07-01 1997-09-30 Monsanto Company Method and device for implantation of large diameter objects in bovines
US5595752A (en) * 1994-07-01 1997-01-21 Monsanto Company Increasing dressing percentage and carcass weight in finishing beef cattle
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US5759519A (en) * 1995-06-07 1998-06-02 Gen-Probe Incorporated Method for the intracellular delivery of biomolecules using thiocationic lipids
US5756352A (en) * 1995-06-07 1998-05-26 Gen-Probe Incorporated Thiocationic lipid-nucleic acid conjugates
US5711964A (en) * 1995-06-07 1998-01-27 United States Of America Method for the intracellular delivery of biomolecules using liposomes containing cationic lipids and vitamin D
US5851548A (en) * 1995-06-07 1998-12-22 Gen-Probe Incorporated Liposomes containing cationic lipids and vitamin D
US5739271A (en) * 1995-06-07 1998-04-14 Gen-Probe Incorporated Thiocationic lipids
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CA2266404A1 (en) * 1996-09-17 1998-03-26 Amur Pharmaceuticals, Inc. Phospholipid drug derivatives
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US7169410B1 (en) * 1998-05-19 2007-01-30 Sdg, Inc. Targeted liposomal drug delivery system
DE10109897A1 (de) * 2001-02-21 2002-11-07 Novosom Ag Fakultativ kationische Liposomen und Verwendung dieser
DE10109898A1 (de) * 2001-02-21 2002-09-05 Novosom Gmbh Lipide mit veränderlicher Ladung
EP1385975B1 (de) * 2001-02-21 2007-01-03 Basf Aktiengesellschaft Verfahren zur herstellung von d-pantothensäure und/oder salze als zusatz zu tierfuttermitteln
US7858117B2 (en) * 2002-02-21 2010-12-28 Novosom Ag Amphoteric liposomes and their use
HU226519B1 (en) * 2002-11-26 2009-03-30 Istvan Dr Horvath Artificial blood made of hemoglobin encapsulated in membrane
WO2005063212A1 (en) * 2003-12-31 2005-07-14 Amorepacific Corporation Cholesteryl hemisuccinate incorporated lipid-based nano-carriers and skin-care compositions for external application containing the same
US20070053845A1 (en) * 2004-03-02 2007-03-08 Shiladitya Sengupta Nanocell drug delivery system
CA2558263A1 (en) * 2004-03-02 2005-09-15 Massachusetts Institute Of Technology Nanocell drug delivery system
JP2008533157A (ja) * 2005-03-14 2008-08-21 マサチューセッツ・インスティテュート・オブ・テクノロジー 疾患および障害の診断および処置のためのナノセル
KR101172066B1 (ko) 2005-09-30 2012-08-10 (주)아모레퍼시픽 스티그마스테릴 헤미숙시네이트를 포함한 지질-기반 약물전달체 및 이를 함유하는 피부 외용제 조성물
US20100068264A1 (en) * 2006-07-12 2010-03-18 University Of South Florida Niosome-hydrogel drug delivery system
US20080317768A1 (en) 2007-06-21 2008-12-25 Boeing Company Bioconjugated nanoparticles
US9814657B2 (en) 2009-04-27 2017-11-14 Premier Dental Products Company Buffered microencapsulated compositions and methods
US10688026B2 (en) * 2009-04-27 2020-06-23 Premier Dental Products Company Buffered microencapsulated compositions and methods
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Also Published As

Publication number Publication date
ES553808A0 (es) 1988-01-01
EP0222771A4 (en) 1988-06-08
FI92463C (fi) 1994-11-25
PT81242A (en) 1985-11-01
ES547326A0 (es) 1986-11-16
NO864960L (no) 1986-12-09
DK591086D0 (da) 1986-12-09
US4891208A (en) 1990-01-02
JPS62502464A (ja) 1987-09-24
HUT42322A (en) 1987-07-28
IE66709B1 (en) 1996-01-24
JPH0798741B2 (ja) 1995-10-25
NZ213601A (en) 1990-03-27
AU4952885A (en) 1986-11-05
FI92463B (fi) 1994-08-15
FI865021A0 (fi) 1986-12-10
AU596953B2 (en) 1990-05-24
IL76600A (en) 1992-12-01
KR890001882B1 (ko) 1989-05-29
FI865021L (fi) 1986-12-10
DK591086A (da) 1986-12-09
PT81242B (pt) 1987-10-20
EP0222771A1 (en) 1987-05-27
IL76600A0 (en) 1986-02-28
CA1262334C (en) 1989-10-17
ES8801085A1 (es) 1988-01-01
KR870700347A (ko) 1987-12-28
WO1986005977A1 (en) 1986-10-23
HU203205B (en) 1991-06-28
IE852336L (en) 1986-10-10
NO173213C (no) 1993-11-17
AU4434589A (en) 1990-05-17
AU609647B2 (en) 1991-05-02
NO173213B (no) 1993-08-09
CA1262334A (en) 1989-10-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050820