ES8607988A1 - Prepn. of ethoxy-carbonyl -phenyl-propyl-alanyl proline maleate - Google Patents
Prepn. of ethoxy-carbonyl -phenyl-propyl-alanyl proline maleateInfo
- Publication number
- ES8607988A1 ES8607988A1 ES545119A ES545119A ES8607988A1 ES 8607988 A1 ES8607988 A1 ES 8607988A1 ES 545119 A ES545119 A ES 545119A ES 545119 A ES545119 A ES 545119A ES 8607988 A1 ES8607988 A1 ES 8607988A1
- Authority
- ES
- Spain
- Prior art keywords
- ethoxy
- carbonyl
- prepn
- propyl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GLCNMRAXBGTUTQ-XXRBRTKDSA-N C(C=C/C(=O)O)(=O)O.C(C)OC(=O)[C@](N(CCC)C1=CC=CC=C1)(C)C(=O)N1[C@H](C(=O)O)CCC1 Chemical compound C(C=C/C(=O)O)(=O)O.C(C)OC(=O)[C@](N(CCC)C1=CC=CC=C1)(C)C(=O)N1[C@H](C(=O)O)CCC1 GLCNMRAXBGTUTQ-XXRBRTKDSA-N 0.000 title 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000011976 maleic acid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Method comprises a) treating mixt. of 1-(N-(1RS)-(ethoxy -carbonyl)-3-phenylpropyl) -2-alanyl)-2-proline epimers with maleic acid in acetone at 0 deg.C to give the corresp. maleate in soln. and b) filtering the soln. to obtain the pptd. 1-(N-(1(S)(ethoxycarbonyl )-3 -phenylpropyl)-2-alanyl -L- proline maleate (I).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES545119A ES8607988A1 (en) | 1985-07-12 | 1985-07-12 | Prepn. of ethoxy-carbonyl -phenyl-propyl-alanyl proline maleate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES545119A ES8607988A1 (en) | 1985-07-12 | 1985-07-12 | Prepn. of ethoxy-carbonyl -phenyl-propyl-alanyl proline maleate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES545119A0 ES545119A0 (en) | 1986-06-01 |
| ES8607988A1 true ES8607988A1 (en) | 1986-06-01 |
Family
ID=8489516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES545119A Expired ES8607988A1 (en) | 1985-07-12 | 1985-07-12 | Prepn. of ethoxy-carbonyl -phenyl-propyl-alanyl proline maleate |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8607988A1 (en) |
-
1985
- 1985-07-12 ES ES545119A patent/ES8607988A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES545119A0 (en) | 1986-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1A | Transfer granted | ||
| PC1A | Transfer granted | ||
| FD1A | Patent lapsed |
Effective date: 20051220 |