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ES8603488A1 - Un procedimiento para la preparacion de un compuesto. - Google Patents

Un procedimiento para la preparacion de un compuesto.

Info

Publication number
ES8603488A1
ES8603488A1 ES525469A ES525469A ES8603488A1 ES 8603488 A1 ES8603488 A1 ES 8603488A1 ES 525469 A ES525469 A ES 525469A ES 525469 A ES525469 A ES 525469A ES 8603488 A1 ES8603488 A1 ES 8603488A1
Authority
ES
Spain
Prior art keywords
alkyl
opt
formula
ester
substd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES525469A
Other languages
English (en)
Other versions
ES525469A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES525469A0 publication Critical patent/ES525469A0/es
Publication of ES8603488A1 publication Critical patent/ES8603488A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrane Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE COMPUESTOS B-LACTAMA, DE FORMULA GENERAL (I), EN LA QUE Z ES -NFCFO O -NHCXR7; X ES OXIGENO O AZUFRE; Y R7 ES HIDROGENO, UN GRUPO ALIFATICO, UN GRUPO CICLOALIFATICO, UN GRUPO ARILO O UN GRUPO HETEROCICLICO, Y SUS SALES Y ESTERES. COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE HACE REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE RX ES UN GRUPO PROTECTOR CARBOXI, CON UN ACIDO ISOCIANICO, UN COMPUESTO DE FORMULA: R1OCON F NCOOR2 Y CON UN COMPUESTO DE FORMULA (III); SEGUNDA, SE HACE REACCIONAR EL COMPUESTO OBTENIDO CON UN COMPUESTO DE FORMULA GENERAL: R7CXX1H; Y POR ULTIMO, SE SEPARA EL GRUPO RX PROTECTOR DEL CARBOXI. DE APLICACION COMO COMPUESTOS INTERCAMBIOS QUIMICOS UTILES EN LA PEPARACION DE DERIVADOS FARMACOLOGICAMENTE ACTIVOS DEL ACIDO CLAVULANICO.
ES525469A 1982-09-11 1983-09-08 Un procedimiento para la preparacion de un compuesto. Expired ES8603488A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8225989 1982-09-11

Publications (2)

Publication Number Publication Date
ES525469A0 ES525469A0 (es) 1985-12-16
ES8603488A1 true ES8603488A1 (es) 1985-12-16

Family

ID=10532862

Family Applications (2)

Application Number Title Priority Date Filing Date
ES525469A Expired ES8603488A1 (es) 1982-09-11 1983-09-08 Un procedimiento para la preparacion de un compuesto.
ES532516A Granted ES532516A0 (es) 1982-09-11 1984-05-16 Un procedimiento para la preparacion de nuevos compuestos de b-lactama

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES532516A Granted ES532516A0 (es) 1982-09-11 1984-05-16 Un procedimiento para la preparacion de nuevos compuestos de b-lactama

Country Status (9)

Country Link
US (1) US4622177A (es)
EP (1) EP0104010B1 (es)
JP (1) JPS5967288A (es)
AU (1) AU1898183A (es)
CA (1) CA1200245A (es)
DE (1) DE3363281D1 (es)
ES (2) ES8603488A1 (es)
GR (1) GR79667B (es)
ZA (1) ZA836693B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5203287A (en) * 1992-08-07 1993-04-20 Tommy Hasbun Oscillating piston engine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
EP0068609A1 (en) * 1981-06-11 1983-01-05 Beecham Group Plc Derivatives of clavulanic acid, a process for their preparation and their use

Also Published As

Publication number Publication date
EP0104010B1 (en) 1986-04-30
ZA836693B (en) 1985-02-27
CA1200245A (en) 1986-02-04
ES525469A0 (es) 1985-12-16
AU1898183A (en) 1984-03-15
ES8507520A1 (es) 1985-09-01
JPS5967288A (ja) 1984-04-16
US4622177A (en) 1986-11-11
ES532516A0 (es) 1985-09-01
DE3363281D1 (en) 1986-06-05
GR79667B (es) 1984-10-31
EP0104010A1 (en) 1984-03-28

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