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ES8603375A1 - Un procedimiento para producir un ester alquilico de un acido 2-(fenoxi sustituido en para)-2-alquil-propionico - Google Patents

Un procedimiento para producir un ester alquilico de un acido 2-(fenoxi sustituido en para)-2-alquil-propionico

Info

Publication number
ES8603375A1
ES8603375A1 ES537642A ES537642A ES8603375A1 ES 8603375 A1 ES8603375 A1 ES 8603375A1 ES 537642 A ES537642 A ES 537642A ES 537642 A ES537642 A ES 537642A ES 8603375 A1 ES8603375 A1 ES 8603375A1
Authority
ES
Spain
Prior art keywords
pref
treating
iii
formula
halocyclopropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537642A
Other languages
English (en)
Other versions
ES537642A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sterwin AG
Original Assignee
Sterwin AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterwin AG filed Critical Sterwin AG
Publication of ES537642A0 publication Critical patent/ES537642A0/es
Publication of ES8603375A1 publication Critical patent/ES8603375A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Luminescent Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ESTERES ALQUILICOS DE ACIDO 2-(FENOXI SUSTITUIDO EN PARA)-2-ALQUIL-PROPIONICO, DE FORMULA (I), EN LA QUE HAL ES UN HALOGENO, PREFERIBLEMENTE CLORO; Y R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES. COMPRENDE LA REACCION DE UN ESTER ALQUILICO DE FORMULA (II), EN LA QUE R TIENE EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON UN HALOGENURO DE FOSFORO, EN UN DISOLVENTE INERTE; SEGUIDA DEL TRATAMIENTO DEL COMPUESTO OBTENIDO CON UNA BASE ORGANICA, COMO UNA TRIALQUILAMINA Y ELIMINACION DEL HIDROHALOGENURO DE LA BASE ORGANICA, FORMADO CONCOMITANTEMENTE; Y, FINALMENTE, TRATAMIENTO DEL PRODUCTO FORMADO CON CLOROFORMO, UN ALCALI FUERTE Y UN CATALIZADOR DE TRANSFERENCIA DE FASES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ESTADOS ASTEROSCLEROTICOS ASOCIADOS CON ELEVADOS NIVELES DE COLESTEROL Y TRIGLICERIDOS EN EL SUERO.
ES537642A 1983-11-15 1984-11-14 Un procedimiento para producir un ester alquilico de un acido 2-(fenoxi sustituido en para)-2-alquil-propionico Expired ES8603375A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838330407A GB8330407D0 (en) 1983-11-15 1983-11-15 Halocyclopropyl-substituted phenoxyalkanoic acids and esters

Publications (2)

Publication Number Publication Date
ES537642A0 ES537642A0 (es) 1985-12-16
ES8603375A1 true ES8603375A1 (es) 1985-12-16

Family

ID=10551756

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537642A Expired ES8603375A1 (es) 1983-11-15 1984-11-14 Un procedimiento para producir un ester alquilico de un acido 2-(fenoxi sustituido en para)-2-alquil-propionico

Country Status (10)

Country Link
EP (1) EP0142979B1 (es)
AT (1) ATE40547T1 (es)
DE (1) DE3476536D1 (es)
DK (1) DK167920B1 (es)
ES (1) ES8603375A1 (es)
FI (1) FI81337C (es)
GB (2) GB8330407D0 (es)
GR (1) GR80950B (es)
NO (1) NO159587C (es)
PT (1) PT79500A (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989006643A1 (en) * 1988-01-22 1989-07-27 Kharkovsky Nauchno-Issledovatelsky Institut Endokr UNDECYLIC ETHER n-CHLOROPHENOXYISOBUTYRIC ACID AND A PHARMACEUTICAL PREPARATION FOR TREATING HYPERLIPEMIA BASED ON IT

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206596A1 (es) * 1972-08-29 1976-08-06 Sterling Drug Inc Procedimiento para preparar compuestos de acidos p-(dihalociclopropil)-fenoxialcanoicos

Also Published As

Publication number Publication date
FI844482A0 (fi) 1984-11-15
DK540084D0 (da) 1984-11-14
EP0142979A3 (en) 1985-12-11
NO844522L (no) 1985-05-20
ES537642A0 (es) 1985-12-16
ATE40547T1 (de) 1989-02-15
GB8330407D0 (en) 1983-12-21
GB8428785D0 (en) 1984-12-27
FI81337C (fi) 1990-10-10
FI81337B (fi) 1990-06-29
DE3476536D1 (en) 1989-03-09
GR80950B (en) 1985-03-14
DK167920B1 (da) 1994-01-03
DK540084A (da) 1985-05-16
EP0142979A2 (en) 1985-05-29
GB2149794B (en) 1986-10-29
NO159587B (no) 1988-10-10
FI844482L (fi) 1985-05-16
GB2149794A (en) 1985-06-19
EP0142979B1 (en) 1989-02-01
NO159587C (no) 1989-01-18
PT79500A (en) 1984-12-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20051010