[go: up one dir, main page]

ES8501797A1 - "un procedimiento para la obtencion de un principio activo fibrinolitico vasal o vascular, quimicamente denominable "enzima angioquinasa"". - Google Patents

"un procedimiento para la obtencion de un principio activo fibrinolitico vasal o vascular, quimicamente denominable "enzima angioquinasa"".

Info

Publication number
ES8501797A1
ES8501797A1 ES511604A ES511604A ES8501797A1 ES 8501797 A1 ES8501797 A1 ES 8501797A1 ES 511604 A ES511604 A ES 511604A ES 511604 A ES511604 A ES 511604A ES 8501797 A1 ES8501797 A1 ES 8501797A1
Authority
ES
Spain
Prior art keywords
active principle
procedure
prepared
producing
enzymatic product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES511604A
Other languages
English (en)
Other versions
ES511604A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Manetti & Roberts Italo Brit
Original Assignee
Manetti & Roberts Italo Brit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manetti & Roberts Italo Brit filed Critical Manetti & Roberts Italo Brit
Publication of ES511604A0 publication Critical patent/ES511604A0/es
Publication of ES8501797A1 publication Critical patent/ES8501797A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN PRINCIPIO ACTIVO FIBRINOLITICO VASAL O VASCULAR, QUIMICAMENTE DENOMINADO ENCIMA ANGIOQUINASA, QUE SE OBTIENE MEDIANTE UN PROCEDIMIENTO DE EXTRACCION A PARTIR DE TEJIDOS CONJUNTIVOS DE MAMIFEROS, TALES COMO LAS RESES DE MATADERO.COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE DESENGRASAN, DESECAN Y REDUCEN A POLVO LOS TEJIDOS DE PARTIDA; SEGUNDA, SE SOMETE DICHO POLVO A LISIS PANCREATINICA, PONIENDOLO EN SUSPENSION EN AGUA A UN PH SUSTANCIALMENTE NEUTRO; TERCERA, SE ACIDIFICA EL LISADO CON ACIDO MINERAL DILUIDO Y SE SEPARA EL LIQUIDO DEL PRECIPITADO; CUARTA, SE AN/ADE SULFATO DE AMONIO A LA PARTE LIQUIDA Y SE RECOGE EL PRECIPITADO OBTENIDO; Y POR ULTIMO, SE FORMA UNA SUSPENSION CON EL PRECIPITADO OBTENIDO, SE LA PURIFICA Y SE RECOGEN A PARTIR DE ELLA LA FRACCIONES QUE CONTIENEN LA ANGIOQUINASA.
ES511604A 1981-04-23 1982-04-22 "un procedimiento para la obtencion de un principio activo fibrinolitico vasal o vascular, quimicamente denominable "enzima angioquinasa"". Expired ES8501797A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48332/81A IT1170913B (it) 1981-04-23 1981-04-23 Procedimento per la produzione di un principio attivo fibrinolitico vasale prodotto enzimatico specifico angiochinasi cosi' ottenuto e sue applicazioni farmaceutiche

Publications (2)

Publication Number Publication Date
ES511604A0 ES511604A0 (es) 1984-12-01
ES8501797A1 true ES8501797A1 (es) 1984-12-01

Family

ID=11265948

Family Applications (1)

Application Number Title Priority Date Filing Date
ES511604A Expired ES8501797A1 (es) 1981-04-23 1982-04-22 "un procedimiento para la obtencion de un principio activo fibrinolitico vasal o vascular, quimicamente denominable "enzima angioquinasa"".

Country Status (16)

Country Link
US (2) US4471053A (es)
EP (1) EP0064036B1 (es)
JP (1) JPS57181019A (es)
AT (1) ATE15071T1 (es)
AU (1) AU548758B2 (es)
CA (1) CA1184138A (es)
DE (1) DE3265559D1 (es)
DK (1) DK180682A (es)
ES (1) ES8501797A1 (es)
IE (1) IE53107B1 (es)
IL (1) IL65448A (es)
IT (1) IT1170913B (es)
NO (1) NO821287L (es)
NZ (1) NZ200254A (es)
PT (1) PT74743B (es)
ZA (1) ZA822703B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA831399B (en) * 1982-03-05 1984-02-29 Health Lab Service Board New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them
JPS58189122A (ja) * 1982-04-30 1983-11-04 Kaken Pharmaceut Co Ltd 高脂血症予防治療剤
JPS61112018A (ja) * 1984-11-06 1986-05-30 Mitsubishi Chem Ind Ltd 線溶増強剤
US5165938A (en) * 1984-11-29 1992-11-24 Regents Of The University Of Minnesota Wound healing agents derived from platelets
US5275812A (en) * 1985-06-07 1994-01-04 The General Hospital Corporation Method of treatment for myocardial infarction
US5248688A (en) * 1986-09-10 1993-09-28 Dudrick Medical Research Fund I, Ltd. Method and substrate composition for treating atherosclerosis
US5032608A (en) * 1986-09-10 1991-07-16 Dudrick Stanley J Method and substrate composition for treating atherosclerosis
HU209955B (en) * 1987-07-01 1994-12-28 Genentech Inc Process for producing pharmaceutical compositions containing tissue- -plasminogen-activator of poor solubility for inhibiting production and regeneration of deformities
US5215908A (en) * 1989-06-13 1993-06-01 Genencor International, Inc. Process for recovery and purification of chymosin
US5449679A (en) * 1994-07-29 1995-09-12 Leonard; Robert J. Process and products for reducing biological fluid levels of a lipid soluble waste
US6979307B2 (en) * 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
US20080199513A1 (en) * 1997-06-24 2008-08-21 Cascade Medical Enterprises, Llc Systems and methods for preparing autologous fibrin glue
US7745106B2 (en) * 1997-06-24 2010-06-29 Cascade Medical Enterprises, Llc Methods and devices for separating liquid components
MXPA00000009A (es) 1998-06-22 2005-09-08 Autologous Wound Therapy Inc Solicitud para patente de utilidad para curativo de heridas mejorado enriquecido con plaquetas.
WO2006102488A1 (en) * 2005-03-22 2006-09-28 Cascade Medical Enterprises, Llc Systems and methods of producing membranes
DE102015010436B4 (de) * 2015-08-14 2019-01-24 Airbus Defence and Space GmbH Wabenkern für dimensionsstabile Sandwichbauteile, dessen Verwendung, Sandwichplatte mit diesem Wabenkern und Verfahren zur Herstellung des Wabenkerns

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3998847A (en) * 1972-10-25 1976-12-21 Schering Aktiengesellschaft 9,10-secoestrane derivatives and their production
US3998947A (en) * 1973-11-30 1976-12-21 Pierre Fabre S.A. Process for obtaining a plasminogen activator
US4245051A (en) * 1978-03-30 1981-01-13 Rockefeller University Human serum plasminogen activator
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions
US4374830A (en) * 1979-10-04 1983-02-22 Research Corp. Platelet aggregating material from equine arterial tissue
US4381346A (en) * 1979-11-13 1983-04-26 Huasin Syed S Isolation of plasminogen activators useful as therapeutic and diagnostic agents
US4390630A (en) * 1980-10-28 1983-06-28 The Regents Of The University Of California Hementin--a fibrinolytic agent

Also Published As

Publication number Publication date
AU8237582A (en) 1982-10-28
US4532129A (en) 1985-07-30
CA1184138A (en) 1985-03-19
ES511604A0 (es) 1984-12-01
EP0064036B1 (en) 1985-08-21
DE3265559D1 (en) 1985-09-26
IL65448A (en) 1985-07-31
JPS57181019A (en) 1982-11-08
IL65448A0 (en) 1982-07-30
IT1170913B (it) 1987-06-03
AU548758B2 (en) 1986-01-02
IE820952L (en) 1982-10-23
EP0064036A1 (en) 1982-11-03
PT74743B (en) 1983-11-09
IE53107B1 (en) 1988-06-22
IT8148332A0 (it) 1981-04-23
DK180682A (da) 1982-10-24
ZA822703B (en) 1983-03-30
NZ200254A (en) 1985-07-12
PT74743A (en) 1982-05-01
US4471053A (en) 1984-09-11
NO821287L (no) 1982-10-25
ATE15071T1 (de) 1985-09-15

Similar Documents

Publication Publication Date Title
ES8501797A1 (es) "un procedimiento para la obtencion de un principio activo fibrinolitico vasal o vascular, quimicamente denominable "enzima angioquinasa"".
AU576365B2 (en) Collagen and or fibrinogen as carrier of drugs for their introduction into cellular lesion areas
ES488120A1 (es) Procedimiento para la preparacion de corticoide-17-alcohil- carbonatos
ES2007341A6 (es) Un procedimiento para producir m-csf
EP0407008A3 (en) Fibronectin fragment
ES8507610A1 (es) Produccion de activador de plasminogeno de tejido humano, utilizando vectores que codifican proteina de dihidrofolato- reductasa.
HUT42955A (en) Process for production of plasminogene activator compositions of stabilized human-tissue
ES456232A1 (es) Perfeccionamientos en aparatos para introducir un volumen predeterminado de solucion enzimatica en el cristalino del ojo.
HUT40804A (en) Process for production of medical preparatives containing n-acetyl neuramin acid
CA2053121A1 (en) Pharmaceutical preparation based on lys-plasminogen
ATE210455T1 (de) Vwf propeptide enthaltendes pharmazeutisches präparat
ES445716A1 (es) Procedimiento para preparar n-acil-l-metionina opticamente pura.
ZA823248B (en) New anti-thromboticum based on polysacharides,method for its preparation and pharmaceutical compositions
HUT46671A (en) Process for production of intermediers suitable for production of quinoline-3-carbonic acid with antibacteric effect
UY25097A1 (es) Proceso para la produccion de heparina
AU570574B2 (en) Depolymerase enzymes and treatment of fireblight
ES8203416A1 (es) Procedimiento de fabricacion de un extracto de levadura
ES2176349T3 (es) Proceso de sililacion.
AU2353688A (en) Modified tissue plasminogen activator
HUT59610A (en) Process for producing pharmaceutical compositions for solving blood clot containing t-pa without glycosilyzing
ES8605583A1 (es) Un procedimiento de producir un activador de plasminogeno monocatenario
HUT58811A (en) Process for producing new polypeptides
ES551375A1 (es) Procedimiento de obtencion de un producto comprimido para aplicacion oftalmologica local.
EP0261088A3 (en) Process for the production of heparanlysopeptide sulphate, the product thus obtained and its therapeutic use
EP0386240A4 (en) Novel polypeptide compounds

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519