ES8304150A1 - "un procedimiento para purificar una sustancia proteinica fisiologicamente activa que tiene actividad antitumoral". - Google Patents
"un procedimiento para purificar una sustancia proteinica fisiologicamente activa que tiene actividad antitumoral".Info
- Publication number
- ES8304150A1 ES8304150A1 ES511376A ES511376A ES8304150A1 ES 8304150 A1 ES8304150 A1 ES 8304150A1 ES 511376 A ES511376 A ES 511376A ES 511376 A ES511376 A ES 511376A ES 8304150 A1 ES8304150 A1 ES 8304150A1
- Authority
- ES
- Spain
- Prior art keywords
- physiologically active
- substance
- active substance
- procedure
- active protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000126 substance Substances 0.000 title abstract 5
- 230000002622 anti-tumorigenesis Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 abstract 5
- 238000002523 gelfiltration Methods 0.000 abstract 3
- 241000283973 Oryctolagus cuniculus Species 0.000 abstract 2
- 238000001042 affinity chromatography Methods 0.000 abstract 2
- 150000001450 anions Chemical class 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 108010062580 Concanavalin A Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- YKCWQPZFAFZLBI-UHFFFAOYSA-N cibacron blue Chemical compound C1=2C(=O)C3=CC=CC=C3C(=O)C=2C(N)=C(S(O)(=O)=O)C=C1NC(C=C1S(O)(=O)=O)=CC=C1NC(N=1)=NC(Cl)=NC=1NC1=CC=CC=C1S(O)(=O)=O YKCWQPZFAFZLBI-UHFFFAOYSA-N 0.000 abstract 1
- 239000002158 endotoxin Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 210000000865 mononuclear phagocyte system Anatomy 0.000 abstract 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO PARA LA FABRICACION DE SUSTANCIAS PROTEINICAS FISIOLOGICAMENTE ACTIVAS, QUE TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTITUMORAL. CONSISTE EN PASAR UNA DISOLUCION CRUDA DE LA SUSTANCIA PROTEINICA DE PH 6,0 A 9,0 A TRAVES DE UN CAMBIADOR DE ANIONES BASICO; ELUIR LA SUSTANCIA FISIOLOGICAMENTE ACTIVA QUE HA SIDO ABSORBIDA; Y SOMETERLA A FILTRACION POR GEL, UTILIZANDO GELES PARA LA SEPARACION DE SUSTANCIAS DE PESO MOLECULAR ENTRE 30.000 Y 70.000, Y ELUYENDO CON UNA DISOLUCION DE PH ENTRE 6,0 Y 9,0.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES511376A ES511376A0 (es) | 1982-04-13 | 1982-04-13 | "un procedimiento para purificar una sustancia proteinica fisiologicamente activa que tiene actividad antitumoral". |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES511376A ES511376A0 (es) | 1982-04-13 | 1982-04-13 | "un procedimiento para purificar una sustancia proteinica fisiologicamente activa que tiene actividad antitumoral". |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8304150A1 true ES8304150A1 (es) | 1983-02-16 |
| ES511376A0 ES511376A0 (es) | 1983-02-16 |
Family
ID=8483993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES511376A Granted ES511376A0 (es) | 1982-04-13 | 1982-04-13 | "un procedimiento para purificar una sustancia proteinica fisiologicamente activa que tiene actividad antitumoral". |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES511376A0 (es) |
-
1982
- 1982-04-13 ES ES511376A patent/ES511376A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES511376A0 (es) | 1983-02-16 |
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