[go: up one dir, main page]

ES8303375A1 - Procedimiento para la fabricacion de derivados 2 substitui- dos del feniltiazol. - Google Patents

Procedimiento para la fabricacion de derivados 2 substitui- dos del feniltiazol.

Info

Publication number
ES8303375A1
ES8303375A1 ES507001A ES507001A ES8303375A1 ES 8303375 A1 ES8303375 A1 ES 8303375A1 ES 507001 A ES507001 A ES 507001A ES 507001 A ES507001 A ES 507001A ES 8303375 A1 ES8303375 A1 ES 8303375A1
Authority
ES
Spain
Prior art keywords
phenyl
substituted
peptic ulcer
thiazole derivatives
derivatives suitable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507001A
Other languages
English (en)
Other versions
ES507001A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jureha Kagaku Kogyo KK
Kureha Corp
Original Assignee
Jureha Kagaku Kogyo KK
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jureha Kagaku Kogyo KK, Kureha Corp filed Critical Jureha Kagaku Kogyo KK
Publication of ES507001A0 publication Critical patent/ES507001A0/es
Publication of ES8303375A1 publication Critical patent/ES8303375A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS 2-SUSTITUIDOS DEL FENILTIAZOL, DE FORMULA (I), EN LA QUE R ES ALQUILO C <- ; R ES HIDROGENO O ALQUILO C <- ; Y N VALE 1-3. CONSISTE EN LA REACCION DE AMONOLISIS DE UN ESTER ALQUILICO INFERIOR DEL ACIDO FENIL-4-METILTIAZOL-5-CARBOXILICO 2-SUSTITUIDO, DE FORMULA (II), EN LA QUE R ES UN ALQUILO C <- Y R Y N SON LOS MISMOS QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE A UNA TEMPERATURA COMPRENDIDA ENTRE -30 C Y 150 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ULCERA PEPTICA.
ES507001A 1980-10-24 1981-10-20 Procedimiento para la fabricacion de derivados 2 substitui- dos del feniltiazol. Expired ES8303375A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55149200A JPS5772975A (en) 1980-10-24 1980-10-24 2-substituted phenylthiazole derviative, and medicine for peptic ulcer containing said derivative as active component

Publications (2)

Publication Number Publication Date
ES507001A0 ES507001A0 (es) 1983-02-01
ES8303375A1 true ES8303375A1 (es) 1983-02-01

Family

ID=15470005

Family Applications (1)

Application Number Title Priority Date Filing Date
ES507001A Expired ES8303375A1 (es) 1980-10-24 1981-10-20 Procedimiento para la fabricacion de derivados 2 substitui- dos del feniltiazol.

Country Status (7)

Country Link
US (1) US4558059A (es)
EP (1) EP0051409B1 (es)
JP (1) JPS5772975A (es)
KR (1) KR850001933B1 (es)
CA (1) CA1163636A (es)
DE (1) DE3162824D1 (es)
ES (1) ES8303375A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879295A (en) * 1986-09-27 1989-11-07 Sawai Pharmaceutical Co., Ltd. N-tetrazolyl thiazolecarboxyamide derivatives and their use
EP0321115B1 (en) * 1987-12-14 1991-08-14 Sawai Pharmaceutical Co., Ltd. Carboxamide derivatives having tetrazole and thiazole rings and their use
ATE142494T1 (de) * 1990-11-30 1996-09-15 Teijin Ltd 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel
US6083966A (en) 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
AU774956B2 (en) * 1998-09-21 2004-07-15 Trustees Of Columbia University In The City Of New York, The Antimalarial agents
US20040132789A1 (en) * 2002-08-22 2004-07-08 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
AU2003270473A1 (en) * 2003-09-09 2005-04-27 University Of Florida Desferrithiocin derivatives and their use as iron chelators
PL1866296T3 (pl) 2005-04-04 2017-05-31 University Of Florida Research Foundation, Inc. Polieterowe analogi desferritiocyny
AU2008229472B2 (en) 2007-03-15 2013-03-14 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
ES2761200T3 (es) 2011-12-16 2020-05-19 Univ Florida Usos de análogos de 4'-desferritiocina
US10010535B2 (en) 2013-11-22 2018-07-03 University Of Florida Research Foundation, Incorporated Desferrithiocin analogs and uses thereof
CN107708693A (zh) 2015-04-27 2018-02-16 佛罗里达大学研究基金会 代谢程序化的金属螯合剂及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1546183A (fr) * 1966-12-07 1968-11-15 Uniroyal Inc Carboxamidothiazoles, leurs substituants et dérivés, leurs procédés de fabrication ainsi que leurs applications et procédés d'application agriculturaux
US3794636A (en) * 1971-09-03 1974-02-26 Uniroyal Ltd Process for preparation of thiazole hydrohalides
US4336389A (en) * 1978-05-15 1982-06-22 Monsanto Company 2-Substituted-4-aryl-5-thiazolecarboxylic acids and their derivatives as safening agents
US4199506A (en) * 1978-05-15 1980-04-22 Monsanto Company 2,4-Disubstituted-5-thiazolecarboxylic acids and derivatives
US4363813A (en) * 1979-07-09 1982-12-14 Kureha Kagaku Kogyo Kabushiki Kaisha 2-(3,4,5-Trimethoxyphenyl)-4,5-disubstituted thiazoles
JPS5657776A (en) * 1979-10-17 1981-05-20 Kumiai Chem Ind Co Ltd Thiazole derivative and fungicide comprising it

Also Published As

Publication number Publication date
CA1163636A (en) 1984-03-13
ES507001A0 (es) 1983-02-01
JPS5772975A (en) 1982-05-07
JPS6148834B2 (es) 1986-10-25
DE3162824D1 (en) 1984-04-26
KR830007603A (ko) 1983-11-04
EP0051409A1 (en) 1982-05-12
KR850001933B1 (ko) 1985-12-31
US4558059A (en) 1985-12-10
EP0051409B1 (en) 1984-03-21

Similar Documents

Publication Publication Date Title
ES8401468A1 (es) Un procedimiento para preparar derivados de nicotinamida.
ES8303375A1 (es) Procedimiento para la fabricacion de derivados 2 substitui- dos del feniltiazol.
EP0675187A3 (en) Liquid crystal compounds and liquid crystal composition containing them.
FI882590A (fi) Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
DE3362894D1 (en) 1-3-dihydro 4-(1-hydroxy-2-amino-ethyl)-2h-indol-2-one derivatives, their salts, process for their preparation, their use as medicines and compositions containing them
ES8506629A1 (es) Un procedimiento para preparar derivados de piridina
RO80925B (ro) Procedeu pentru prepararea unor derivati de nitrotiofen
IE800494L (en) Aminoalkylfluorenes
ATE50773T1 (de) Alkylresorcinolphosphite.
ES8303372A1 (es) Procedimiento para la fabricacion de un compuesto de fenil-5-alquiltiazolidina-4-ona, 2-substituida
ES8202818A1 (es) Un procedimiento para preparar derivados de tetrazolilcuma- rina
ES474449A1 (es) Procedimiento de obtencion de ureas y tioureas con actividad farmacologica.
ES440723A1 (es) Procedimiento para la produccion de nuevos compuestos orga- nicos.
DE3061188D1 (en) 2-sulfonyl-quinoxalines, processes for their preparation and their use as microbicides
ES464045A1 (es) Un procedimiento para la produccion de una gamma-pirona.
ES454823A1 (es) Procedimiento para la preparacion de derivados de imidazo (1,2-a) piridina.
ATE50762T1 (de) 3-(indan-5-yloxy (oder thio)&gt;cyclopentancarbons|ure-analogeund sie enthaltendes behandlungsmittel.
AU564799B2 (en) Composition for prophylactic and preventative of ketosis in livestock
ES8303381A1 (es) Procedimiento para la fabricacion de un compuesto de fenil- 1,3-perhidrotiacina-4-ona, 2-substituida
ES8206550A1 (es) Un procedimiento para la preparacion de derivados de 2-desoxi-3-5-di-o-alquilcarbonil-5-fluorurina.
ES465093A1 (es) Procedimiento para la preparacion de un compuesto util como agente antirinovirus.
HUT54688A (en) Process for producing compounds utilizable for treating ulcus and pharmaceutical compositions containing them as active components
ES8403891A1 (es) Un procedimiento para la preparacion de un derivado del acido furiloxazolila-cetico
ES8505653A1 (es) Procedimiento para preparar un n-alquil-(3 o 4)piperidinil benzoato
DE3561818D1 (en) Isoxazoloquinolinone derivatives, process and intermediates for their preparation, use as medicaments and compositions containing them

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603