ES8203612A1 - Procedimiento de preparacion de imuno globulina g nativa li-bre de actividad anticomplementaria - Google Patents
Procedimiento de preparacion de imuno globulina g nativa li-bre de actividad anticomplementariaInfo
- Publication number
- ES8203612A1 ES8203612A1 ES502788A ES502788A ES8203612A1 ES 8203612 A1 ES8203612 A1 ES 8203612A1 ES 502788 A ES502788 A ES 502788A ES 502788 A ES502788 A ES 502788A ES 8203612 A1 ES8203612 A1 ES 8203612A1
- Authority
- ES
- Spain
- Prior art keywords
- igg
- anticomplement
- manufacture
- way
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000002391 anti-complement effect Effects 0.000 title 1
- 108010008730 anticomplement Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 1
- 230000003171 anti-complementary effect Effects 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002198 insoluble material Substances 0.000 abstract 1
- 229920001993 poloxamer 188 Polymers 0.000 abstract 1
- -1 polyethylenepropylene Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PREPARACION DE INMUNO GLOBULINA G ADMINISTRABLE POR VIA INTRAVENOSA. SE PARTE DE UNA SOLUCION ACUOSA DE INMUNO GLOBULINA G DEL 5 AL 10 POR 100, A LA QUE SE AÑADE UNPOLIMERO TIPO POLIETILENPOLIPROPILENGLICOL EN UNA PREPARACION DEL 1 AL 3 POR 100, MANTENIENDO LA DISOLUCION EN PH ENTRE 5 Y 8 EN UN INTERVALO DE TEMPERATURA TAL QUE LA INMUNO GLOBULINA G SEA ESTABLE, PROCEDIENDOSE A CONTINUACION A SEPARAR POR FILTRACION LAS IMPUREZAS INSOLUBLES, CON LO QUE LA INMUNO GLOBULINA G QUEDA PURIFICADA LIBRE DE ACTIVIDAD ANTICOMPLEMENTARIA.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES502788A ES502788A0 (es) | 1981-06-04 | 1981-06-04 | Procedimiento de preparacion de imuno globulina g nativa li-bre de actividad anticomplementaria |
JP56120621A JPS57206625A (en) | 1981-06-04 | 1981-07-31 | Manufacture of non-anticomplement igg |
DE19823208523 DE3208523A1 (de) | 1981-06-04 | 1982-03-10 | Igg-praeparat, das frei von einer antikomplementaeren aktivitaet ist, sowie verfahren zu seiner herstellung |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES502788A ES502788A0 (es) | 1981-06-04 | 1981-06-04 | Procedimiento de preparacion de imuno globulina g nativa li-bre de actividad anticomplementaria |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8203612A1 true ES8203612A1 (es) | 1982-04-01 |
ES502788A0 ES502788A0 (es) | 1982-04-01 |
Family
ID=8482493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES502788A Granted ES502788A0 (es) | 1981-06-04 | 1981-06-04 | Procedimiento de preparacion de imuno globulina g nativa li-bre de actividad anticomplementaria |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS57206625A (es) |
DE (1) | DE3208523A1 (es) |
ES (1) | ES502788A0 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2706466B1 (fr) * | 1993-06-14 | 1995-08-25 | Aetsrn | Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré. |
FR2708467B1 (fr) * | 1993-07-30 | 1995-10-20 | Pasteur Merieux Serums Vacc | Préparations d'immunoglobulines stabilisées et procédé pour leur préparation. |
CA2330610A1 (en) | 1998-05-07 | 1999-11-11 | Corixa Corporation | Adjuvant composition and methods for its use |
-
1981
- 1981-06-04 ES ES502788A patent/ES502788A0/es active Granted
- 1981-07-31 JP JP56120621A patent/JPS57206625A/ja active Pending
-
1982
- 1982-03-10 DE DE19823208523 patent/DE3208523A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ES502788A0 (es) | 1982-04-01 |
JPS57206625A (en) | 1982-12-18 |
DE3208523A1 (de) | 1983-05-05 |
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