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ES8105287A1 - Procedimiento para preparar un derivado de piperidina - Google Patents

Procedimiento para preparar un derivado de piperidina

Info

Publication number
ES8105287A1
ES8105287A1 ES492149A ES492149A ES8105287A1 ES 8105287 A1 ES8105287 A1 ES 8105287A1 ES 492149 A ES492149 A ES 492149A ES 492149 A ES492149 A ES 492149A ES 8105287 A1 ES8105287 A1 ES 8105287A1
Authority
ES
Spain
Prior art keywords
naphthyl
production
mycotic agent
piperidine derivative
piperidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492149A
Other languages
English (en)
Other versions
ES492149A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES492149A0 publication Critical patent/ES492149A0/es
Publication of ES8105287A1 publication Critical patent/ES8105287A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE (R)-N-TRANS-3-FENIL-2-PROPENIL-2-(1-NAFTIL)PIPERIDINA. CONSISTE EN EFECTUAR ALGUNO DE LOS SIGUIENTES PROCEDIMIENTOS: 1. DISOCIACION DE LA FORMA RACEMICA N-TRANS-3-FENIL-2-PROPENIL-2-(1-NAFTIL)PIPERIDINA EN SUS ANTIPODAS OPTICAMENTE ACTIVOS, AISLANDOSE EL ANTIPODA (R). EL PROCESO SE EFECTUA POR CRISTALIZACION FRACCIONADA DE PARES DE SAL DIASTEREOISOMERICAS CON UN ACIDO OPTICAMENTE ACTIVO TAL COMO ACIDO (-)DIO-O, O-O-TOLUIL-(L)-TARTARICO. 2. REACCION DE (R)-2-(1-NAFTIL)PIPERIDINA CON UN COMPUESTO (I) EN UN DISOLVENTE INERTE TAL COMO BENCENO, TOLUENO, DIEXANO O DIMETILFORMAMIDA. LA TEMPERATURA ES LA AMBIENTE. EL PROCESO SE EFECTUA EN PRESENCIA DE UN AGENTE LIGADOR DE ACIDOS TAL COMO CARBONATOS DE METAL ALCALINO CARBONATO DE SODIO). *FORMULA*
ES492149A 1979-06-08 1980-06-04 Procedimiento para preparar un derivado de piperidina Expired ES8105287A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH537279 1979-06-08

Publications (2)

Publication Number Publication Date
ES492149A0 ES492149A0 (es) 1981-05-16
ES8105287A1 true ES8105287A1 (es) 1981-05-16

Family

ID=4292451

Family Applications (1)

Application Number Title Priority Date Filing Date
ES492149A Expired ES8105287A1 (es) 1979-06-08 1980-06-04 Procedimiento para preparar un derivado de piperidina

Country Status (14)

Country Link
JP (1) JPS562964A (es)
AU (1) AU5912180A (es)
BE (1) BE883673A (es)
DE (1) DE3020113A1 (es)
DK (1) DK247180A (es)
ES (1) ES8105287A1 (es)
FR (1) FR2462426A1 (es)
GB (1) GB2051799A (es)
IL (1) IL60248A0 (es)
IT (1) IT8048887A0 (es)
NL (1) NL8003250A (es)
PT (1) PT71362B (es)
SE (1) SE8004234L (es)
ZA (1) ZA803403B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2664592B1 (fr) * 1990-07-10 1994-09-02 Adir Nouveaux derives de la piperidine, de la tetrahydropyridine et de la pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
GB9513750D0 (en) * 1995-07-06 1995-09-06 Sandoz Ltd Use of allylamines
JP4859552B2 (ja) * 2006-06-21 2012-01-25 株式会社ダイゾー エアゾール製品

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000896B1 (en) * 1977-08-19 1982-10-13 Sandoz Ag Propenyl amines, processes for their production and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
PT71362B (en) 1981-06-25
ZA803403B (en) 1982-01-27
NL8003250A (nl) 1980-12-10
ES492149A0 (es) 1981-05-16
AU5912180A (en) 1980-12-11
IL60248A0 (en) 1980-09-16
SE8004234L (sv) 1980-12-09
DE3020113A1 (de) 1980-12-18
PT71362A (en) 1980-07-01
GB2051799A (en) 1981-01-21
IT8048887A0 (it) 1980-06-04
BE883673A (fr) 1980-12-08
FR2462426A1 (fr) 1981-02-13
DK247180A (da) 1980-12-09
JPS562964A (en) 1981-01-13

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