ES556659A0 - Un procedimiento para preparar derivados de 1-aminobut-3-eno - Google Patents

Un procedimiento para preparar derivados de 1-aminobut-3-eno

Info

Publication number: ES556659A0
Authority: ES; Spain
Prior art keywords: aminobut; eno; procedure; preparing derivatives; derivatives
Prior art date: 1985-06-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES556659A

Other languages

English (en)

Other versions

ES8800927A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novo Nordisk AS

Original Assignee

Novo Industri AS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-26

Filing date

1986-06-25

Publication date

1987-12-01

1986-06-25 Application filed by Novo Industri AS filed Critical Novo Industri AS

1987-12-01 Publication of ES556659A0 publication Critical patent/ES556659A0/es

1987-12-01 Publication of ES8800927A1 publication Critical patent/ES8800927A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Anesthesiology (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ES556659A 1985-06-26 1986-06-25 Un procedimiento para preparar derivados de 1-aminobut-3-eno Expired ES8800927A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK288385A DK288385D0 (da)	1985-06-26	1985-06-26	Aminosyrederivater

Publications (2)

Publication Number	Publication Date
ES556659A0 true ES556659A0 (es)	1987-12-01
ES8800927A1 ES8800927A1 (es)	1987-12-01

Family

ID=8116767

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES556659A Expired ES8800927A1 (es)	1985-06-26	1986-06-25	Un procedimiento para preparar derivados de 1-aminobut-3-eno

Country Status (16)

Country	Link
US (1)	US5010090A (es)
EP (1)	EP0236342B1 (es)
JP (1)	JPH07103116B2 (es)
AT (1)	ATE67196T1 (es)
AU (1)	AU599326B2 (es)
CA (1)	CA1284503C (es)
DK (2)	DK288385D0 (es)
ES (1)	ES8800927A1 (es)
FI (1)	FI89355C (es)
GR (1)	GR861650B (es)
IE (1)	IE59084B1 (es)
LU (1)	LU90130I2 (es)
NZ (1)	NZ216657A (es)
PT (1)	PT82841B (es)
WO (1)	WO1987000171A1 (es)
ZA (1)	ZA864608B (es)

Families Citing this family (46)

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DK704488D0 (da) *	1988-12-19	1988-12-19	Novo Industri As	Nye n-substituerede azaheterocykliske carboxylsyrer
DK288385D0 (da) *	1985-06-26	1985-06-26	Novo Industri As	Aminosyrederivater
DK588189D0 (da) *	1989-11-22	1989-11-22	Novo Nordisk As	Nye heterocykliske carboxylsyrer
DK58291D0 (da) *	1991-04-02	1991-04-02	Novo Nordisk As	Krystalinsk stof og dets fremstilling
TR199700873T1 (xx) *	1995-02-28	1998-01-21	H. Lund-Beck A/S	4-Aminotetrahidrobenzizoksazol veya -izotiazol bile�ikleri.
US5962449A (en)	1995-04-07	1999-10-05	Novo Nordisk A/S	Tricyclic compounds in treating hyperalgesic conditions and NIDDM
DK0830132T3 (da) *	1995-05-05	2002-04-29	Novo Nordisk As	Farmaceutisk formulering indeholdende tiagabinhydrochlorid samt fremgangsmåden til dets fremstilling
US6191165B1 (en)	1996-05-31	2001-02-20	Allelix Neuroscience Inc.	Pharmaceutical for treatment of neurological and neuropsychiatric disorders
UA52661C2 (uk) *	1996-06-14	2003-01-15	Ново Нордіск А/С	Безводна кристалічна форма гідрохлориду r(-)-n-(4,4-ди(3-метилтієн-2-іл)бут-3-еніл) ніпекотинової кислоти
US5958951A (en) *	1996-06-14	1999-09-28	Novo Nordiskials	Modified form of the R(-)-N-(4,4-di(3-methylthien-2-yl)but-3-enyl)-nipecotic acid hydrochloride
US5914333A (en) *	1996-07-31	1999-06-22	Novo Nordisk A/S	Treatment of psychotic disorders
IE970588A1 (en)	1997-08-01	2000-08-23	Elan Corp Plc	Controlled release pharmaceutical compositions containing tiagabine
JP2001511450A (ja) *	1997-08-01	2001-08-14	エランコーポレーシヨンピーエルシー	チアガビンを含有する制御放出性の医薬組成物
US6503926B2 (en) *	1998-09-04	2003-01-07	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
US6288083B1 (en)	1998-09-04	2001-09-11	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
DE19840611A1 (de) *	1998-09-05	2000-03-09	Klaus Wanner	GABA-uptake-Inhibitoren mit Pyrrolidinstruktur
AU1892800A (en) *	1999-01-12	2000-08-01	Takeda Chemical Industries Ltd.	Compositions for treating frequent urination and urinary incontinence
US6872734B2 (en)	2000-10-20	2005-03-29	Abbott Laboratories	Use of tiagabine for treatment of diabetic neuropathy and migraine
AU2002215159A1 (en)	2000-11-30	2002-06-11	Pfizer Products Inc.	Combination of GABA agonists and sorbitol dehydrogenase inhibitors
AU2002215160A1 (en) *	2000-11-30	2002-06-11	Pfizer Products Inc.	Combination of gaba agonists and aldose reductase inhibitors
UA75114C2 (en)	2001-02-16	2006-03-15	Allelix Neuroscience Inc	GlyT-1 INHIBITORS
JP4625637B2 (ja)	2002-02-22	2011-02-02	シャイアエルエルシー	活性物質送達系及び活性物質を保護し投与する方法
CN1382441A (zh) *	2002-05-21	2002-12-04	中国科学院上海生命科学研究院	γ－氨基丁酸转运蛋白抑制剂在制备镇痛药物中的应用
MXPA05012317A (es) *	2003-05-16	2006-01-30	Pfizer Prod Inc	Combinaciones terapeuticas de agentes antipsicoticos atipicos con agentes moduladores del gaba anticonvulsivos o benzodiazepinas.
DK1691811T3 (da)	2003-12-11	2014-10-20	Sunovion Pharmaceuticals Inc	Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression
US7667042B2 (en) *	2003-12-24	2010-02-23	Sun Pharma Advanced Research Company Ltd.	Stable polymorphic forms of an anticonvulsant
CN1314684C (zh) *	2003-12-24	2007-05-09	中国科学院上海有机化学研究所	噻加宾及其消旋体和s－构型的合成方法及其无定形粉末的制法
BRPI0507190A (pt) *	2004-01-29	2007-06-26	Pfizer Prod Inc	combinação de moduladores do ácido gama-aminobutìrico e antagonistas de 5-ht1b receptores
WO2005092886A1 (en) *	2004-03-29	2005-10-06	Ranbaxy Laboratories Limited	Process for the preparation of amorphous form of tiagabine
US20080269495A1 (en) *	2004-08-04	2008-10-30	Prosenjit Bose	Process for Preparation of Piperidine Carboxylic Acid
EP2258357A3 (en)	2005-08-26	2011-04-06	Braincells, Inc.	Neurogenesis with acetylcholinesterase inhibitor
CA2620333A1 (en)	2005-08-26	2007-03-01	Braincells, Inc.	Neurogenesis by muscarinic receptor modulation
WO2007047978A2 (en)	2005-10-21	2007-04-26	Braincells, Inc.	Modulation of neurogenesis by pde inhibition
EP2314289A1 (en)	2005-10-31	2011-04-27	Braincells, Inc.	Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en)	2006-03-08	2010-08-26	Braincells, Inc.	Modulation of neurogenesis by nootropic agents
CA2651813A1 (en)	2006-05-09	2007-11-22	Braincells, Inc.	Neurogenesis by modulating angiotensin
US7678808B2 (en)	2006-05-09	2010-03-16	Braincells, Inc.	5 HT receptor mediated neurogenesis
US20080064727A1 (en) *	2006-08-18	2008-03-13	Cephalon, Inc.	Crystalline forms of tiagabine hydrochloride
US20080051435A1 (en) *	2006-08-18	2008-02-28	Cephalon, Inc.	Crystalline and amorphous forms of tiagabine
EP2068872A1 (en)	2006-09-08	2009-06-17	Braincells, Inc.	Combinations containing a 4-acylaminopyridine derivative
US20100184806A1 (en)	2006-09-19	2010-07-22	Braincells, Inc.	Modulation of neurogenesis by ppar agents
US20090082401A1 (en) *	2007-09-25	2009-03-26	Protia, Llc	Deuterium-enriched tiagabine
WO2010099217A1 (en)	2009-02-25	2010-09-02	Braincells, Inc.	Modulation of neurogenesis using d-cycloserine combinations
CN101857591B (zh) *	2009-04-09	2013-06-05	北京京卫燕康药物研究所有限公司	盐酸噻加宾晶型及其制备方法
CN102070624B (zh) *	2011-01-25	2013-04-10	赵学清	一种盐酸噻加宾的合成方法及无水盐酸噻加宾的制备方法
CN102827152B (zh) *	2012-09-17	2014-11-05	扬子江药业集团四川海蓉药业有限公司	噻加宾的制备方法及其前体化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4383999A (en) *	1981-05-26	1983-05-17	Smithkline Beckman Corporation	Inhibition of GABA uptake by N-substituted azaheterocyclic carboxylic acids and their esters
US4514414A (en) *	1982-10-25	1985-04-30	Smithkline Beckman Corporation	N-Substituted pyrrolidineacetic acids and their esters
DK288385D0 (da) *	1985-06-26	1985-06-26	Novo Industri As	Aminosyrederivater
DK165692C (da) *	1986-01-07	1993-11-08	Novo Nordisk As	Phenylbutenderivater, fremgangsmaade til fremstilling heraf, farmaceutisk praeparat indeholdende disse, samt anvendelse af disse til fremstilling af et medikament nyttigt til inhibering af gaba-optagelse i mennesker

1985
- 1985-06-26 DK DK288385A patent/DK288385D0/da not_active Application Discontinuation
1986
- 1986-06-20 ZA ZA864608A patent/ZA864608B/xx unknown
- 1986-06-24 CA CA000512333A patent/CA1284503C/en not_active Expired - Lifetime
- 1986-06-25 GR GR861650A patent/GR861650B/el unknown
- 1986-06-25 NZ NZ216657A patent/NZ216657A/xx unknown
- 1986-06-25 PT PT82841A patent/PT82841B/pt unknown
- 1986-06-25 ES ES556659A patent/ES8800927A1/es not_active Expired
- 1986-06-25 IE IE170286A patent/IE59084B1/en not_active IP Right Cessation
- 1986-06-26 AU AU61336/86A patent/AU599326B2/en not_active Expired
- 1986-06-26 JP JP61503845A patent/JPH07103116B2/ja not_active Expired - Lifetime
- 1986-06-26 WO PCT/DK1986/000076 patent/WO1987000171A1/en active IP Right Grant
- 1986-06-26 AT AT86904114T patent/ATE67196T1/de active
- 1986-06-26 EP EP86904114A patent/EP0236342B1/en not_active Expired - Lifetime
1987
- 1987-02-25 FI FI870810A patent/FI89355C/fi not_active IP Right Cessation
- 1987-02-26 DK DK100887A patent/DK156398C/da not_active IP Right Cessation
1988
- 1988-10-07 US US07/254,557 patent/US5010090A/en not_active Expired - Lifetime
1997
- 1997-08-29 LU LU90130C patent/LU90130I2/fr unknown

Also Published As

Publication number	Publication date
EP0236342B1 (en)	1991-09-11
NZ216657A (en)	1989-10-27
FI89355C (fi)	1993-09-27
AU6133686A (en)	1987-01-30
AU599326B2 (en)	1990-07-19
FI89355B (fi)	1993-06-15
LU90130I2 (fr)	1997-10-24
JPS62503172A (ja)	1987-12-17
DK156398B (da)	1989-08-14
JPH07103116B2 (ja)	1995-11-08
US5010090A (en)	1991-04-23
DK288385D0 (da)	1985-06-26
DK156398C (da)	1990-01-08
DK100887D0 (da)	1987-02-26
IE861702L (en)	1986-12-26
FI870810A0 (fi)	1987-02-25
EP0236342A1 (en)	1987-09-16
PT82841A (en)	1986-07-01
ATE67196T1 (de)	1991-09-15
FI870810A (fi)	1987-02-25
DK100887A (da)	1987-02-26
CA1284503C (en)	1991-05-28
ES8800927A1 (es)	1987-12-01
PT82841B (pt)	1989-01-17
GR861650B (en)	1986-10-30
ZA864608B (en)	1987-02-25
WO1987000171A1 (en)	1987-01-15
IE59084B1 (en)	1994-01-12

Publication	Publication Date	Title
ES556659A0 (es)	1987-12-01	Un procedimiento para preparar derivados de 1-aminobut-3-eno
DE69015418D1 (de)	1995-02-09	Energieversorgung.
DE68925000D1 (de)	1996-01-18	Dampferzeuger.
DE69017080D1 (de)	1995-03-30	VHF-Gleichstrom-Gleichstrom-Leistungsversorgung.
NO894428D0 (no)	1989-11-07	Tetralinderivater.
DE3860607D1 (de)	1990-10-18	Dampferzeuger.
KR900700425A (ko)	1990-08-13	2,3-디플루오로페놀 유도체
ES1014131Y (es)	1991-07-16	Armario surtidor.
DE69022955D1 (de)	1995-11-16	Leistungszufuhr.
DE58905817D1 (de)	1993-11-11	Durchlaufdampferzeuger.
FI885145A0 (fi)	1988-11-09	Laddande spis foer nattelektricitet.
DE69014868D1 (de)	1995-01-19	Membranoxygenator.
ES1008693Y (es)	1989-12-01	Tapon perfeccionado.
ES1004540Y (es)	1989-04-01	Figura componible perfeccionada.
ES1010746Y (es)	1991-05-01	Tapon precinto perfeccionado.
ES1011557Y (es)	1990-11-01	Frigorifico conservador-congelador perfeccionado.
ES1006955Y (es)	1989-08-16	Tapon aplicador perfeccionado.
ES1005303Y (es)	1989-05-16	Hidrante perfeccionado.
ES1015902Y (es)	1992-07-01	Tapon perfeccionado.
ES1006492Y (es)	1989-07-01	Cerramiento perfeccionado.
ES1006043Y (es)	1989-05-16	Capsuladora perfeccionada.
ES1007202Y (es)	1989-07-16	Tapon-precinto perfeccionado.
ES1004978Y (es)	1989-04-01	Contenedor-expositor perfeccionado.
ES1004378Y (es)	1989-04-01	Calendario-agenda perfeccionado.
ES1007563Y (es)	1989-08-16	Futbolin-billar perfeccionado.

Legal Events

Date	Code	Title	Description
2008-06-16	FD1A	Patent lapsed	Effective date: 20071016