ES555548A0 - Procedimiento para preparar derivados de quinazolina - Google Patents
Procedimiento para preparar derivados de quinazolinaInfo
- Publication number
- ES555548A0 ES555548A0 ES555548A ES555548A ES555548A0 ES 555548 A0 ES555548 A0 ES 555548A0 ES 555548 A ES555548 A ES 555548A ES 555548 A ES555548 A ES 555548A ES 555548 A0 ES555548 A0 ES 555548A0
- Authority
- ES
- Spain
- Prior art keywords
- group
- heteroatom
- quinazoline derivatives
- procedure
- halogeno
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical class N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 title 1
- 125000005842 heteroatom Chemical group 0.000 abstract 5
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 2
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858513754A GB8513754D0 (en) | 1985-05-31 | 1985-05-31 | Anti-cancer quinazoline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES555548A0 true ES555548A0 (es) | 1987-12-01 |
| ES8800911A1 ES8800911A1 (es) | 1987-12-01 |
Family
ID=10579966
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES555548A Expired ES8800911A1 (es) | 1985-05-31 | 1986-05-30 | Procedimiento para preparar derivados de quinazolina |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5236927A (es) |
| EP (1) | EP0204529B1 (es) |
| JP (1) | JPS61282368A (es) |
| AT (1) | ATE87621T1 (es) |
| AU (1) | AU592271B2 (es) |
| DE (1) | DE3688150T2 (es) |
| DK (1) | DK255786A (es) |
| ES (1) | ES8800911A1 (es) |
| FI (1) | FI862303A (es) |
| GB (2) | GB8513754D0 (es) |
| GR (1) | GR861418B (es) |
| HU (1) | HUT45512A (es) |
| IL (1) | IL78910A0 (es) |
| NO (1) | NO862170L (es) |
| NZ (1) | NZ216363A (es) |
| PT (1) | PT82682B (es) |
| ZA (1) | ZA864051B (es) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
| GB8707053D0 (en) * | 1987-03-25 | 1987-04-29 | Ici Plc | Anti-tumour agents |
| US4857530A (en) * | 1987-11-03 | 1989-08-15 | Warner-Lambert Company | Substituted quinazolinones as anticancer agents |
| GB8809978D0 (en) * | 1988-04-27 | 1988-06-02 | Ici Plc | Anti-tumour agents |
| EP0365763A1 (en) * | 1988-09-30 | 1990-05-02 | Agouron Pharmaceuticals, Inc. | Antiproliferative cyclic compounds |
| US5286726A (en) * | 1990-04-12 | 1994-02-15 | The Regents Of The University Of Michigan | Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases |
| US6762188B1 (en) | 1990-06-19 | 2004-07-13 | Smithkline Beecham Corporation | Pharmaceutically active benzoquinazoline compounds |
| GB9013615D0 (en) * | 1990-06-19 | 1990-08-08 | Wellcome Found | Pharmaceutical compounds |
| GB9105771D0 (en) * | 1991-03-19 | 1991-05-01 | Cancer Res Inst Royal | Anti-cancer compounds |
| GB9205320D0 (en) * | 1992-03-11 | 1992-04-22 | Ici Plc | Anti-tumour compounds |
| GB9205907D0 (en) * | 1992-03-18 | 1992-04-29 | Cancer Res Inst Royal | Anti-cancer compounds |
| US5430148A (en) * | 1992-03-31 | 1995-07-04 | Agouron Pharmaceuticals, Inc. | Antiproliferative quinazolines |
| GB9223352D0 (en) * | 1992-11-06 | 1992-12-23 | Ici Plc | Tricyclic compounds |
| US7262058B2 (en) * | 2001-03-09 | 2007-08-28 | Nonda Katopodis | Method for determining lipid associated sialoprotein in body fluids |
| WO2004036870A2 (en) * | 2002-10-18 | 2004-04-29 | Koninklijke Philips Electronics N.V. | Method and system for metadata protection in tv-anytime |
| US20060052345A1 (en) * | 2002-11-04 | 2006-03-09 | Nps Pharmaceuticals, Inc. | Quinazolinone compounds as calcilytics |
| US20070015774A1 (en) * | 2005-07-15 | 2007-01-18 | Schering Corporation | Quinazoline derivatives useful in cancer treatment |
| CN101263125A (zh) * | 2005-07-15 | 2008-09-10 | 先灵公司 | 用于癌症治疗的喹唑啉衍生物 |
| CA2663436A1 (en) | 2006-10-04 | 2008-04-10 | Pfizer Products Inc. | Pyrido[4,3-d]pyrimidin-4(3h)-one derivatives as calcium receptor antagonists |
| US8680291B2 (en) | 2007-10-26 | 2014-03-25 | The Regents Of The University Of California | Diarylhydantoin compounds |
| SMT201700430T1 (it) | 2009-06-25 | 2018-01-11 | Alkermes Pharma Ireland Ltd | Composti eterociclici per il trattamento di disturbi neurologici e psicologici |
| AU2010339689B2 (en) * | 2010-01-07 | 2015-02-19 | Alkermes Pharma Ireland Limited | Quaternary ammonium salt prodrugs |
| WO2011163594A2 (en) | 2010-06-24 | 2011-12-29 | Alkermes, Inc. | Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
| LT3156056T (lt) | 2011-03-18 | 2024-02-26 | Alkermes Pharma Ireland Limited | Farmacinės kompozicijos, apimančios sorbitano esterius |
| JP6219918B2 (ja) | 2012-03-19 | 2017-10-25 | アルカームス ファーマ アイルランド リミテッド | グリセロールエステルを含む医薬組成物 |
| WO2013142205A1 (en) | 2012-03-19 | 2013-09-26 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising benzyl alcohol |
| US10004807B2 (en) | 2012-03-19 | 2018-06-26 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising fatty acid esters |
| JP6654042B2 (ja) | 2012-09-19 | 2020-02-26 | アルカームス ファーマ アイルランド リミテッド | 貯蔵安定性が改善された医薬組成物 |
| US9452131B2 (en) | 2014-03-20 | 2016-09-27 | Alkermes Pharma Ireland Limited | Aripiprazole formulations having increased injection speeds |
| JP7384812B2 (ja) | 2018-03-05 | 2023-11-21 | アルカームス ファーマ アイルランド リミテッド | アリピプラゾール投与戦略 |
| WO2024028999A1 (ja) * | 2022-08-03 | 2024-02-08 | Ils株式会社 | Ｎ－［４－メチルアミノベンゾイル］－ｌ－グルタミン酸ジエチルエステルの製造方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1021196A (en) * | 1964-02-20 | 1966-03-02 | Parke Davis & Co | Novel amino acids and means for producing the same |
| US3471498A (en) * | 1967-08-11 | 1969-10-07 | Parke Davis & Co | Certain n-p-((2,4-diamino-6-quinazolinyl)-methyl)benzoylamino acids |
| EP0031237B1 (en) * | 1979-12-19 | 1984-10-17 | National Research Development Corporation | Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents |
| GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
-
1985
- 1985-05-31 GB GB858513754A patent/GB8513754D0/en active Pending
-
1986
- 1986-05-26 IL IL78910A patent/IL78910A0/xx unknown
- 1986-05-30 FI FI862303A patent/FI862303A/fi not_active Application Discontinuation
- 1986-05-30 GB GB08613184A patent/GB2175903B/en not_active Expired
- 1986-05-30 DE DE8686304148T patent/DE3688150T2/de not_active Expired - Fee Related
- 1986-05-30 ES ES555548A patent/ES8800911A1/es not_active Expired
- 1986-05-30 HU HU862288A patent/HUT45512A/hu unknown
- 1986-05-30 NZ NZ216363A patent/NZ216363A/xx unknown
- 1986-05-30 ZA ZA864051A patent/ZA864051B/xx unknown
- 1986-05-30 AT AT86304148T patent/ATE87621T1/de not_active IP Right Cessation
- 1986-05-30 PT PT82682A patent/PT82682B/pt not_active IP Right Cessation
- 1986-05-30 DK DK255786A patent/DK255786A/da not_active Application Discontinuation
- 1986-05-30 JP JP61125587A patent/JPS61282368A/ja active Pending
- 1986-05-30 GR GR861418A patent/GR861418B/el unknown
- 1986-05-30 NO NO862170A patent/NO862170L/no unknown
- 1986-05-30 EP EP86304148A patent/EP0204529B1/en not_active Expired - Lifetime
- 1986-05-30 AU AU58220/86A patent/AU592271B2/en not_active Ceased
-
1990
- 1990-12-12 US US07/625,695 patent/US5236927A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61282368A (ja) | 1986-12-12 |
| NO862170L (no) | 1986-12-01 |
| DE3688150T2 (de) | 1993-07-29 |
| PT82682A (en) | 1986-06-01 |
| GB2175903B (en) | 1988-10-12 |
| GB2175903A (en) | 1986-12-10 |
| EP0204529A3 (en) | 1987-11-19 |
| PT82682B (pt) | 1988-03-03 |
| DE3688150D1 (de) | 1993-05-06 |
| GR861418B (en) | 1986-09-26 |
| GB8613184D0 (en) | 1986-07-02 |
| AU5822086A (en) | 1986-12-04 |
| AU592271B2 (en) | 1990-01-04 |
| HUT45512A (en) | 1988-07-28 |
| DK255786A (da) | 1986-12-01 |
| FI862303A0 (fi) | 1986-05-30 |
| US5236927A (en) | 1993-08-17 |
| EP0204529A2 (en) | 1986-12-10 |
| IL78910A0 (en) | 1986-09-30 |
| EP0204529B1 (en) | 1993-03-31 |
| FI862303A (fi) | 1986-12-01 |
| DK255786D0 (da) | 1986-05-30 |
| NZ216363A (en) | 1989-07-27 |
| ATE87621T1 (de) | 1993-04-15 |
| GB8513754D0 (en) | 1985-07-03 |
| ES8800911A1 (es) | 1987-12-01 |
| ZA864051B (en) | 1987-01-28 |
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