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ES537023A0 - Un procedimiento para la preparacion de nuevos antagonistas de los leucotrienos. - Google Patents

Un procedimiento para la preparacion de nuevos antagonistas de los leucotrienos.

Info

Publication number
ES537023A0
ES537023A0 ES537023A ES537023A ES537023A0 ES 537023 A0 ES537023 A0 ES 537023A0 ES 537023 A ES537023 A ES 537023A ES 537023 A ES537023 A ES 537023A ES 537023 A0 ES537023 A0 ES 537023A0
Authority
ES
Spain
Prior art keywords
procedure
preparation
new
leucotrene
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES537023A
Other languages
English (en)
Other versions
ES8602588A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Frosst Canada and Co
Original Assignee
Merck Frosst Canada and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada and Co filed Critical Merck Frosst Canada and Co
Publication of ES537023A0 publication Critical patent/ES537023A0/es
Publication of ES8602588A1 publication Critical patent/ES8602588A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES537023A 1983-10-27 1984-10-24 Un procedimiento para la preparacion de nuevos antagonistas de los leucotrienos. Expired ES8602588A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54601383A 1983-10-27 1983-10-27
US57316984A 1984-01-23 1984-01-23

Publications (2)

Publication Number Publication Date
ES537023A0 true ES537023A0 (es) 1985-12-01
ES8602588A1 ES8602588A1 (es) 1985-12-01

Family

ID=27068091

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537023A Expired ES8602588A1 (es) 1983-10-27 1984-10-24 Un procedimiento para la preparacion de nuevos antagonistas de los leucotrienos.

Country Status (5)

Country Link
EP (1) EP0140684B1 (es)
CA (1) CA1254578A (es)
DE (1) DE3482685D1 (es)
DK (1) DK511884A (es)
ES (1) ES8602588A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1309557C (en) 1985-06-18 1992-10-27 Robert N. Young Leukotriene antagonists
US4885309A (en) * 1986-08-01 1989-12-05 Hoffmann-La Roche Inc. Therapeutic treatment of leukotriene-mediated dermal inflammation by topical administration of 3,4-dihydro-2H-1-benzopyran derivatives
NZ222878A (en) * 1986-12-17 1991-02-26 Merck Frosst Canada Inc 3-hetero-substituted-n-benzyl-indole derivatives, and pharmaceutical compositions
US4906658A (en) * 1987-04-21 1990-03-06 Merck Frosst Canada, Inc. Fluoro-sulfones
MX13485A (es) * 1987-10-19 1993-05-01 Pfizer Procedimiento para obtener tetralinas, cromados y compuestos relacionados, sustituidos
ZA911453B (en) * 1990-03-19 1991-11-27 Squibb & Sons Inc Method of protecting against and/or treating ulcerative gastrointestinal conditions using a thromoboxane,a2 receptor antagonist and combination useful in preventing and/or treating ulcers and/or inflammation
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
CZ280133B6 (cs) * 1991-11-25 1995-11-15 Eli Lilly And Company Substituovaný fenylfenolleukotrienový antagonist a farmaceutický prostředek, který ho obsahuje
CN1035001C (zh) * 1993-01-02 1997-05-28 伊莱利利公司 取代的苯基苯酚基白三烯拮抗物
US5409944A (en) * 1993-03-12 1995-04-25 Merck Frosst Canada, Inc. Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
ES2079997A1 (es) * 1993-06-15 1996-01-16 Lilly Co Eli Compuestos de fenil fenol sustituidos antagonistas de leucotrieno, procedimiento para su obtencion y formulaciones farmaceuticas de los mismos.
US5410054A (en) * 1993-07-20 1995-04-25 Merck Frosst Canada, Inc. Heteroaryl quinolines as inhibitors of leukotriene biosynthesis
WO1996023786A1 (en) * 1995-01-31 1996-08-08 Merck Frosst Canada Inc. 5-methanesulfonamido-3h-isobenzofuran-1-ones as inhibitors of cyclooxygenase-2
AU783720B2 (en) * 2000-01-26 2005-12-01 Kyorin Pharmaceutical Co. Ltd. Eye drops
JP2010530419A (ja) 2007-06-20 2010-09-09 メルク・シャープ・エンド・ドーム・コーポレイション ジフェニル置換アルカン

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2058785B (en) * 1979-09-05 1983-05-25 Glaxo Group Ltd Phenol derivatives
DE3265715D1 (en) * 1981-03-24 1985-10-03 Fisons Plc Anti srs-a carboxylic acid derivatives, processes for their production and pharmaceutical formulations containing them
US4499299A (en) * 1981-12-30 1985-02-12 Ici Americas Inc. Pharmaceutically active phenylcarboxylic acid derivatives
ATE22072T1 (de) * 1982-09-30 1986-09-15 Merck Frosst Canada Inc Leukotrienantagonisten, deren herstellung und diese enthaltende zusammensetzungen.

Also Published As

Publication number Publication date
DE3482685D1 (de) 1990-08-16
EP0140684B1 (en) 1990-07-11
CA1254578A (en) 1989-05-23
EP0140684A3 (en) 1986-07-23
DK511884A (da) 1985-04-28
DK511884D0 (da) 1984-10-26
EP0140684A2 (en) 1985-05-08
ES8602588A1 (es) 1985-12-01

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