ES523191A0 - Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas - Google Patents

Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas

Info

Publication number: ES523191A0
Authority: ES; Spain
Prior art keywords: sub; hydrogen; lower alkyl; benzazepines; tetrahydro
Prior art date: 1982-06-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES523191A

Other languages

English (en)

Other versions

ES8503666A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Aventis Pharmaceuticals Inc

Original Assignee

Hoechst Roussel Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-06-14

Filing date

1983-06-13

Publication date

1985-03-01

1983-06-13 Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc

1985-03-01 Publication of ES523191A0 publication Critical patent/ES523191A0/es

1985-03-01 Publication of ES8503666A1 publication Critical patent/ES8503666A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

ES523191A 1982-06-14 1983-06-13 Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas Expired ES8503666A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/387,916 US4988690A (en)	1982-06-14	1982-06-14	1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant use thereof

Publications (2)

Publication Number	Publication Date
ES523191A0 true ES523191A0 (es)	1985-03-01
ES8503666A1 ES8503666A1 (es)	1985-03-01

Family

ID=23531838

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES523191A Expired ES8503666A1 (es)	1982-06-14	1983-06-13	Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas

Country Status (17)

Country	Link
US (1)	US4988690A (es)
EP (1)	EP0096838B1 (es)
JP (1)	JPS595165A (es)
KR (1)	KR900001214B1 (es)
AT (1)	ATE26263T1 (es)
AU (1)	AU570920B2 (es)
CA (1)	CA1214460A (es)
DE (1)	DE3370621D1 (es)
DK (1)	DK270983A (es)
ES (1)	ES8503666A1 (es)
FI (1)	FI78473C (es)
GR (1)	GR78291B (es)
HU (1)	HU190902B (es)
IE (1)	IE55404B1 (es)
IL (1)	IL68964A (es)
PT (1)	PT76864B (es)
ZA (1)	ZA834309B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5015639A (en) *	1987-03-27	1991-05-14	Schering Corporation	Substituted benzazepines, their preparation and pharmaceutical compositions containing them
ZA882080B (en) *	1987-03-27	1989-04-26	Schering Corp	Substituted benzazepines,their preparation and pharmaceutical compositions containing them
ZA885824B (en) *	1987-08-14	1989-04-26	Merrell Dow Pharma	Novel antidepressants
US5202319A (en) *	1991-09-23	1993-04-13	Hoechst-Roussel Pharmaceuticals Inc.	Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines
US5639482A (en) *	1993-11-10	1997-06-17	Crary; Ely J.	Composition for control and prevention of diabetic retinopathy
AU2002228725A1 (en) *	2000-11-30	2002-06-11	Advanced Research And Technology Institute, Inc.	Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds
US6953787B2 (en) *	2002-04-12	2005-10-11	Arena Pharmaceuticals, Inc.	5HT2C receptor modulators
EA016558B1 (ru) *	2003-06-17	2012-05-30	Арена Фармасьютикалз, Инк.	Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором
AU2004267016B2 (en)	2003-06-17	2011-11-24	Arena Pharmaceuticals, Inc.	Benzazepine derivatives useful for the treatment of 5HT2C receptor associated diseases
US20080009478A1 (en) *	2003-10-22	2008-01-10	Arena Pharmaceuticals, Inc.	Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2c Receptor Associated Diseases
US20070275949A1 (en) *	2003-10-22	2007-11-29	Arena Pharmaceuticals, Inc.	Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2C Receptor Associated Diseases
KR101281919B1 (ko)	2004-12-21	2013-07-03	아레나 파마슈티칼스, 인크.	(ｒ)-8-클로로-1-메틸-2,3,4,5-테트라히드로-1ｈ-3-벤즈아제핀 히드로클로라이드의 결정질 형태
KR101426850B1 (ko)	2004-12-23	2014-08-05	아레나 파마슈티칼스, 인크.	5ｈｔ２ｃ 수용체 조정물질 조성물 및 그의 사용 방법
JP5199997B2 (ja)	2006-04-03	2013-05-15	アリーナファーマシューティカルズ，インコーポレイテッド	８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンズアゼピンおよびこれに関連する中間体を調製するためのプロセス
ES2522587T3 (es) *	2006-12-05	2014-11-17	Arena Pharmaceuticals, Inc.	Procesos para preparar (R)-8-cloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzacepina e intermedios de la misma
JP5566282B2 (ja)	2007-05-10	2014-08-06	アルバニーモレキュラーリサーチ，インコーポレイテッド	アリールオキシ置換およびヘテロアリールオキシ置換テトラヒドロベンゾアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
WO2009111004A1 (en)	2008-03-04	2009-09-11	Arena Pharmaceuticals, Inc.	Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
WO2010148207A2 (en)	2009-06-18	2010-12-23	Arena Pharmaceuticals, Inc.	Processes for the preparation of 5-ht2c receptor agonists
KR20130112848A (ko)	2010-06-02	2013-10-14	아레나 파마슈티칼스, 인크.	5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
WO2012030938A1 (en)	2010-09-01	2012-03-08	Arena Pharmaceuticals, Inc.	Salts of lorcaserin with optically active acids
JP6272695B2 (ja)	2010-09-01	2018-01-31	エーザイ・アール・アンド・ディー・マネジメント株式会社	体重管理のために有用な５−ｈｔ２ｃアゴニストの改変放出剤形
WO2012030957A2 (en)	2010-09-01	2012-03-08	Arena Pharmaceuticals, Inc.	Non-hygroscopic salts of 5-ht2c agonists
KR20140091458A (ko)	2010-09-01	2014-07-21	아레나 파마슈티칼스, 인크.	신장 손상을 갖는 개체에 대한 로카세린의 투여
CA2886875A1 (en)	2012-10-09	2014-04-17	Arena Pharmaceuticals, Inc.	Method of weight management

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5233687A (en) *	1975-09-11	1977-03-14	Shionogi & Co Ltd	Process for preparation of 1,5-dihydro-2h-1,4-benzodiazepine-2-on deri vatives
JPS5481290A (en) *	1977-11-17	1979-06-28	Smithkline Corp	Benzazepin compound

1982
- 1982-06-14 US US06/387,916 patent/US4988690A/en not_active Expired - Fee Related
1983
- 1983-06-08 AT AT83105610T patent/ATE26263T1/de not_active IP Right Cessation
- 1983-06-08 DE DE8383105610T patent/DE3370621D1/de not_active Expired
- 1983-06-08 EP EP83105610A patent/EP0096838B1/en not_active Expired
- 1983-06-10 FI FI832092A patent/FI78473C/fi not_active IP Right Cessation
- 1983-06-11 KR KR1019830002597A patent/KR900001214B1/ko active IP Right Grant
- 1983-06-13 IE IE1384/83A patent/IE55404B1/en unknown
- 1983-06-13 CA CA000430280A patent/CA1214460A/en not_active Expired
- 1983-06-13 ZA ZA834309A patent/ZA834309B/xx unknown
- 1983-06-13 GR GR71648A patent/GR78291B/el unknown
- 1983-06-13 HU HU832096A patent/HU190902B/hu not_active IP Right Cessation
- 1983-06-13 DK DK270983A patent/DK270983A/da not_active Application Discontinuation
- 1983-06-13 ES ES523191A patent/ES8503666A1/es not_active Expired
- 1983-06-13 IL IL68964A patent/IL68964A/xx unknown
- 1983-06-13 JP JP58104343A patent/JPS595165A/ja active Granted
- 1983-06-14 AU AU15764/83A patent/AU570920B2/en not_active Ceased
- 1983-06-14 PT PT76864A patent/PT76864B/pt unknown

Also Published As

Publication number	Publication date
DK270983D0 (da)	1983-06-13
US4988690A (en)	1991-01-29
JPH0365342B2 (es)	1991-10-11
ZA834309B (en)	1984-03-28
PT76864B (en)	1986-02-27
DE3370621D1 (en)	1987-05-07
JPS595165A (ja)	1984-01-12
IE831384L (en)	1983-12-14
DK270983A (da)	1983-12-15
EP0096838B1 (en)	1987-04-01
PT76864A (en)	1983-07-01
FI78473B (fi)	1989-04-28
GR78291B (es)	1984-09-26
AU1576483A (en)	1983-12-22
FI832092L (fi)	1983-12-15
EP0096838A1 (en)	1983-12-28
FI832092A0 (fi)	1983-06-10
ES8503666A1 (es)	1985-03-01
CA1214460A (en)	1986-11-25
KR840005103A (ko)	1984-11-03
HU190902B (en)	1986-12-28
AU570920B2 (en)	1988-03-31
IE55404B1 (en)	1990-09-12
KR900001214B1 (ko)	1990-02-28
FI78473C (fi)	1989-08-10
IL68964A (en)	1988-03-31
ATE26263T1 (de)	1987-04-15
IL68964A0 (en)	1983-10-31

Publication	Publication Date	Title
ES523191A0 (es)	1985-03-01	Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas
ATE37179T1 (de)	1988-09-15	Dihydropyridazinone.
MY109937A (en)	1997-10-31	Substituted azoles, processes for the preparation thereof, agents containing these, and the use thereof.
EP0202577A3 (en)	1989-08-02	N(acyldipeptidyl)-aminoglycols
ES8401961A1 (es)	1984-01-01	Procedimiento para la preparacion de nuevas n-(4-indolil-piperidino-alcohil-bencimidazolonas sustituidas.
GR3004250T3 (es)	1993-03-31
ZA816259B (en)	1983-04-27	2-(1,4-benzodioxan-2-ylalkyl)imidazoles useful as antidepressants
ES8800571A1 (es)	1987-11-01	Procedimiento para preparar un derivado de 1,3-oxazolidina-2-ona.
ES550003A0 (es)	1986-12-01	Procedimiento para preparar imidazo (1,2-c)pirimidinas
ES8604219A1 (es)	1986-01-16	Un procedimiento para la preparacion de benzoquinolicinas
ES527739A0 (es)	1985-04-16	Un procedimiento para preparar derivados de pirimidina
HK1032916A1 (en)	2001-08-10	N,n'-bis(sulfonyl)hydrazines useful as antineoplastic agents
ES8504180A1 (es)	1985-04-01	Procedimiento para preparar nuevos derivados de piperidina
ES8305758A1 (es)	1983-05-01	"un procedimiento para la preparacion de 2-(1,4-benzodioxan-2-il-metil)-imidazolina".
PL246418A1 (en)	1985-07-02	Process for preparing n-/3-trifluoromethylphenyl/-n'-propargylpiperazine
ATE30323T1 (de)	1987-11-15	5-phenylaethenylbenzimidazole.
ES553600A0 (es)	1987-06-16	Un procedimiento para la preparacion de nuevos derivados de diamina.
ES8703457A1 (es)	1987-02-16	Un procedimiento para la preparacion de nuevos derivados de tiacetona.
GR880100112A (en)	1988-12-16	Method of preparation of new acetamide deravatives of dihydro-2,3 phenyl-3 benzophouranone-2
PT73527A (en)	1981-09-01	Process for the preparation of n-sulphenylated ureas having fungicidal effect
JPS5636414A (en)	1981-04-09	Anticonvulsant agent containing omega-aminoalkoxystilbene or its acid addition salt as active constituent
KR880002858A (ko)	1988-05-12	퀴날딘 아미드 유도체의 제조방법
DE3467297D1 (en)	1987-12-17	Benzobicyclononane amino derivatives with anticonvulsive properties