ES516556A0 - Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos. - Google Patents

Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos.

Info

Publication number: ES516556A0
Authority: ES; Spain
Prior art keywords: azaaralcanoil; azaalcanoil; carboxi; carboxylics; acides
Prior art date: 1980-11-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES516556A

Other languages

English (en)

Other versions

ES8401026A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee

Ciba Geigy AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-11-03

Filing date

1982-10-15

Publication date

1983-12-01

1982-10-15 Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG

1983-12-01 Publication of ES8401026A1 publication Critical patent/ES8401026A1/es

1983-12-01 Publication of ES516556A0 publication Critical patent/ES516556A0/es

Status Granted legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

ES516556A 1980-11-03 1982-10-15 Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos. Granted ES516556A0 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US20376980A	1980-11-03	1980-11-03
US23991881A	1981-03-03	1981-03-03

Publications (2)

Publication Number	Publication Date
ES8401026A1 ES8401026A1 (es)	1983-12-01
ES516556A0 true ES516556A0 (es)	1983-12-01

Family

ID=26898886

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES506784A Expired ES8303329A1 (es)	1980-11-03	1981-11-02	Procedimiento para la obtencion de acidos 1-carboxi-(azaal- canoil o azaaralcanoil)-indolin-2-carboxilicos.
ES516555A Granted ES516555A0 (es)	1980-11-03	1982-10-15	Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos.
ES516556A Granted ES516556A0 (es)	1980-11-03	1982-10-15	Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos.

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
ES506784A Expired ES8303329A1 (es)	1980-11-03	1981-11-02	Procedimiento para la obtencion de acidos 1-carboxi-(azaal- canoil o azaaralcanoil)-indolin-2-carboxilicos.
ES516555A Granted ES516555A0 (es)	1980-11-03	1982-10-15	Procedimiento para la obtencion de acidos 1-carboxi-(azaalcanoil o azaaralcanoil)-indolin-2-carboxilicos.

Country Status (13)

Country	Link
EP (1)	EP0051301A1 (es)
AU (1)	AU7702281A (es)
CA (1)	CA1172258A (es)
DD (1)	DD201888A5 (es)
DK (1)	DK483681A (es)
ES (3)	ES8303329A1 (es)
FI (1)	FI813422L (es)
GB (1)	GB2086390B (es)
GR (1)	GR74689B (es)
HU (1)	HU185324B (es)
IL (1)	IL64185A0 (es)
NO (1)	NO813694L (es)
PT (1)	PT73916B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN156096B (es) *	1981-03-19	1985-05-11	Usv Pharma Corp
DE3226768A1 (de) *	1981-11-05	1983-05-26	Hoechst Ag, 6230 Frankfurt	Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
IE55867B1 (en) *	1981-12-29	1991-02-14	Hoechst Ag	New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
ATE25244T1 (de) *	1981-12-29	1987-02-15	Hoechst Ag	Neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung.
DE3210496A1 (de) *	1982-03-23	1983-10-06	Hoechst Ag	Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
US4520205A (en) *	1982-06-28	1985-05-28	American Home Products Corporation	Chemical resolution of (+)-2,3-dihydroindole-2-carboxylic acid
US5175306A (en) *	1983-01-31	1992-12-29	Hoechst Aktiengesellschaft	Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
FR2546886B2 (fr) *	1983-06-06	1986-05-16	Adir	Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant
DE3324263A1 (de) *	1983-07-06	1985-01-17	Hoechst Ag, 6230 Frankfurt	Derivate der 2-azabicyclo(3.1.0)hexan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(3.1.0)hexan-derivate als zwischenprodukte und verfahren zu deren herstellung
DE3333454A1 (de) *	1983-09-16	1985-04-11	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3333455A1 (de) *	1983-09-16	1985-04-11	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3413710A1 (de) *	1984-04-12	1985-10-24	Hoechst Ag, 6230 Frankfurt	Verfahren zur behandlung der herzinsuffizienz
US5684016A (en) *	1984-04-12	1997-11-04	Hoechst Aktiengesellschaft	Method of treating cardiac insufficiency
DE3431541A1 (de) *	1984-08-28	1986-03-06	Hoechst Ag, 6230 Frankfurt	Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US5231080A (en) *	1985-10-15	1993-07-27	Hoechst Aktiengesellschaft	Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) *	1986-03-27	1993-07-27	Hoechst Aktiengesellschaft	Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) *	1986-10-02	1988-04-14	Hoechst Ag	Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) *	1986-11-21	1988-06-01	Hoechst Ag	Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) *	1987-07-03	1989-01-12	Hoechst Ag	Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
TW197945B (es) *	1990-11-27	1993-01-11	Hoechst Ag
US5504080A (en) *	1992-10-28	1996-04-02	Bristol-Myers Squibb Co.	Benzo-fused lactams
AU7186094A (en) *	1993-06-30	1995-01-24	Ciba-Geigy Ag	Antihypertensive tricyclic azepine derivatives useful as inhibitors of enkephalinase and ace

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL58849A (en) *	1978-12-11	1983-03-31	Merck & Co Inc	Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4303583A (en) *	1979-08-13	1981-12-01	American Home Products Corporation	1H,5H-[1,4]Thiazepino[4,3-a]indole-1,5-diones
IE52663B1 (en) *	1980-04-02	1988-01-20	Warner Lambert Co	Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids

1981
- 1981-10-29 GB GB8132559A patent/GB2086390B/en not_active Expired
- 1981-10-30 EP EP81109378A patent/EP0051301A1/de not_active Withdrawn
- 1981-10-30 FI FI813422A patent/FI813422L/fi not_active Application Discontinuation
- 1981-10-30 CA CA000389117A patent/CA1172258A/en not_active Expired
- 1981-11-02 GR GR66399A patent/GR74689B/el unknown
- 1981-11-02 ES ES506784A patent/ES8303329A1/es not_active Expired
- 1981-11-02 PT PT73916A patent/PT73916B/pt unknown
- 1981-11-02 AU AU77022/81A patent/AU7702281A/en not_active Abandoned
- 1981-11-02 DK DK483681A patent/DK483681A/da not_active Application Discontinuation
- 1981-11-02 NO NO813694A patent/NO813694L/no unknown
- 1981-11-02 HU HU813251A patent/HU185324B/hu unknown
- 1981-11-02 IL IL64185A patent/IL64185A0/xx unknown
- 1981-11-03 DD DD81234586A patent/DD201888A5/de unknown
1982
- 1982-10-15 ES ES516555A patent/ES516555A0/es active Granted
- 1982-10-15 ES ES516556A patent/ES516556A0/es active Granted

Also Published As

Publication number	Publication date
ES8401026A1 (es)	1983-12-01
CA1172258A (en)	1984-08-07
GR74689B (es)	1984-07-03
FI813422L (fi)	1982-05-04
PT73916B (en)	1983-11-30
GB2086390B (en)	1984-06-06
ES506784A0 (es)	1983-02-01
ES8401025A1 (es)	1983-12-01
ES8303329A1 (es)	1983-02-01
DD201888A5 (de)	1983-08-17
GB2086390A (en)	1982-05-12
AU7702281A (en)	1982-05-13
DK483681A (da)	1982-05-04
NO813694L (no)	1982-05-04
EP0051301A1 (de)	1982-05-12
PT73916A (en)	1981-12-01
IL64185A0 (en)	1982-02-28
ES516555A0 (es)	1983-12-01
HU185324B (en)	1985-01-28

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