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ES514919A0 - "un procedimiento para preparar un derivado de antraciclina". - Google Patents

"un procedimiento para preparar un derivado de antraciclina".

Info

Publication number
ES514919A0
ES514919A0 ES514919A ES514919A ES514919A0 ES 514919 A0 ES514919 A0 ES 514919A0 ES 514919 A ES514919 A ES 514919A ES 514919 A ES514919 A ES 514919A ES 514919 A0 ES514919 A0 ES 514919A0
Authority
ES
Spain
Prior art keywords
anthracicline
derivative
preparing
procedure
anthracicline derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES514919A
Other languages
English (en)
Other versions
ES8306765A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microbial Chemistry Research Foundation
Original Assignee
Microbial Chemistry Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Chemistry Research Foundation filed Critical Microbial Chemistry Research Foundation
Publication of ES8306765A1 publication Critical patent/ES8306765A1/es
Publication of ES514919A0 publication Critical patent/ES514919A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/215Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/26Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydration of carbon-to-carbon triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES514919A 1980-09-22 1982-08-11 "un procedimiento para preparar un derivado de antraciclina". Granted ES514919A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55130645A JPS5756494A (en) 1980-09-22 1980-09-22 New anthracyclin derivative

Publications (2)

Publication Number Publication Date
ES8306765A1 ES8306765A1 (es) 1983-06-01
ES514919A0 true ES514919A0 (es) 1983-06-01

Family

ID=15039201

Family Applications (2)

Application Number Title Priority Date Filing Date
ES505656A Granted ES505656A0 (es) 1980-09-22 1981-09-21 Un procedimiento para preparar nuevos derivados de antraci- clina
ES514919A Granted ES514919A0 (es) 1980-09-22 1982-08-11 "un procedimiento para preparar un derivado de antraciclina".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES505656A Granted ES505656A0 (es) 1980-09-22 1981-09-21 Un procedimiento para preparar nuevos derivados de antraci- clina

Country Status (10)

Country Link
US (1) US4355026A (es)
EP (2) EP0086430B1 (es)
JP (1) JPS5756494A (es)
AU (1) AU542707B2 (es)
CA (1) CA1177070A (es)
DE (1) DE3163896D1 (es)
DK (1) DK154419C (es)
ES (2) ES505656A0 (es)
PH (3) PH18087A (es)
ZA (1) ZA816564B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411834A (en) * 1978-02-09 1983-10-25 Farmitalia Carlo Erba, S.P.A. Preparation of II-deoxy anthracycline antibiotics
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
CA1187434A (en) * 1981-08-11 1985-05-21 Akihiro Yoshimoto Anthracycline antibiotics and their preparation method
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same
FR2551057B1 (fr) * 1983-08-30 1986-07-18 Hoechst Lab Nouveaux aglycones utiles pour la preparation des antibiotiques et des antitumoraux de la serie des anthracyclines et leurs procedes de preparation
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
IT1190399B (it) * 1985-10-04 1988-02-16 Zambon Spa Processo per la preparazione di composti carbonilici otticamente attivi
JPH0372492A (ja) * 1990-08-04 1991-03-27 Mercian Corp アントラサイクリン誘導体及びその製造方法
WO1999058543A1 (en) * 1998-05-13 1999-11-18 Instytut Farmaceutyczny New n-alkyloxycarbonyl derivatives of monosaccharides l-acosamine and l-daunosamine
EP1165578B1 (en) * 1999-03-19 2012-02-22 Waldemar Priebe Methods and compositions for the manufacture of c-3' and c-4' anthracycline antibiotics

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1527892A (fr) * 1967-03-15 1968-06-07 Rhone Poulenc Sa Nouveau procédé de préparation de l'antibiotique 13057 r.p.
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
US4020270A (en) * 1974-05-02 1977-04-26 Societa' Farmaceutici Italia S.P.A. L-lyxohex-1-enopyranose derivative
GB1470860A (en) * 1974-10-29 1977-04-21 Farmaceutici Italia Anthracycline glycosides
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
GB1527050A (en) * 1976-06-19 1978-10-04 Farmaceutici Italia Optically active anthracyclinones
NL7900869A (nl) * 1978-02-09 1979-08-13 Erba Farmitalia Anthracyclinenantibiotica.
GB2036021B (en) * 1978-11-21 1983-04-13 Erba Farmitalia Antitumour antibiotics
GB2067552B (en) * 1980-01-16 1984-02-29 Erba Farmitalia Anthracyline derivatives

Also Published As

Publication number Publication date
EP0049403B1 (en) 1984-05-30
US4355026A (en) 1982-10-19
EP0049403A2 (en) 1982-04-14
DK154419B (da) 1988-11-14
PH18087A (en) 1985-03-20
AU542707B2 (en) 1985-03-07
JPS6121559B2 (es) 1986-05-27
DE3163896D1 (en) 1984-07-05
DK154419C (da) 1989-04-10
ES8306765A1 (es) 1983-06-01
DK418581A (da) 1982-03-23
ES8302733A1 (es) 1982-12-01
ES505656A0 (es) 1982-12-01
EP0086430A1 (en) 1983-08-24
PH18633A (en) 1985-08-23
ZA816564B (en) 1982-09-29
AU7553281A (en) 1982-04-01
CA1177070A (en) 1984-10-30
EP0086430B1 (en) 1985-11-06
PH18162A (en) 1985-04-03
EP0049403A3 (en) 1982-06-02
JPS5756494A (en) 1982-04-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970505