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ES488706A1 - Procedimiento para la preparacion de isomeros opticos de amidinas heterociclicas de condensacion espiro - Google Patents

Procedimiento para la preparacion de isomeros opticos de amidinas heterociclicas de condensacion espiro

Info

Publication number
ES488706A1
ES488706A1 ES488706A ES488706A ES488706A1 ES 488706 A1 ES488706 A1 ES 488706A1 ES 488706 A ES488706 A ES 488706A ES 488706 A ES488706 A ES 488706A ES 488706 A1 ES488706 A1 ES 488706A1
Authority
ES
Spain
Prior art keywords
alkoxy
substituted
nitrogen atom
hydrogen
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES488706A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES488706A1 publication Critical patent/ES488706A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/05—Compounds containing nitro groups bound to a carbon skeleton having nitro groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Procedimiento para la preparación de isómeros ópticos de amidinas heterocíclicas de condensación espiro, de las fórmulas XII ó XVII **(Fórmula)** donde n es 1 ó 2; R1 y R2 significa hidrógeno o radicales alcohilo, que en común con el átomo de nitrógeno pueden formar un anillo de 5, 6 ó 7 miembros, el cual puede estar substituido con grupos alcohilo de 1 a 3 átomos de carbono, alcoxi de 1 a 2 átomos de carbono, hidroxi o alcoxicarbonilo de 1 a 4 átomos de carbono, y donde uno de los átomos de carbono puede estar reemplazado también por un átomo de oxígeno, azufre o nitrógeno.
ES488706A 1979-02-23 1980-02-18 Procedimiento para la preparacion de isomeros opticos de amidinas heterociclicas de condensacion espiro Expired ES488706A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792907070 DE2907070A1 (de) 1979-02-23 1979-02-23 Heterocyclische spiroverknuepfte amidine und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES488706A1 true ES488706A1 (es) 1980-09-16

Family

ID=6063739

Family Applications (5)

Application Number Title Priority Date Filing Date
ES488702A Expired ES488702A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488705A Expired ES488705A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de endo-aril-exo-pirrolin-amidinas
ES488703A Expired ES488703A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488704A Expired ES488704A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488706A Expired ES488706A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de isomeros opticos de amidinas heterociclicas de condensacion espiro

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES488702A Expired ES488702A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488705A Expired ES488705A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de endo-aril-exo-pirrolin-amidinas
ES488703A Expired ES488703A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro
ES488704A Expired ES488704A1 (es) 1979-02-23 1980-02-18 Procedimiento para la preparacion de amidinas heterociclicasde condensacion espiro

Country Status (11)

Country Link
US (1) US4277470A (es)
EP (1) EP0014996B1 (es)
JP (1) JPS55120563A (es)
AT (1) ATE914T1 (es)
AU (1) AU534240B2 (es)
CA (1) CA1140930A (es)
DE (2) DE2907070A1 (es)
DK (1) DK77280A (es)
ES (5) ES488702A1 (es)
IL (1) IL59441A0 (es)
ZA (1) ZA801041B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
SE9904121D0 (sv) 1999-11-15 1999-11-15 Gustaf Jederstroem Hydrophobe biomolecular structure

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2911409A (en) * 1955-07-18 1959-11-03 Upjohn Co 2-spiro-substituted pyrrolidines
US2931805A (en) * 1958-11-10 1960-04-05 Smith Kline French Lab Spiro [bicyclo [2. 2. 1] heptane-2, 2'-alkylenimines]

Also Published As

Publication number Publication date
ES488705A1 (es) 1980-09-16
ES488704A1 (es) 1980-09-16
ES488702A1 (es) 1980-09-16
ZA801041B (en) 1981-03-25
AU534240B2 (en) 1984-01-12
AU5580680A (en) 1980-08-28
DE3060314D1 (en) 1982-06-09
EP0014996A1 (de) 1980-09-03
ATE914T1 (de) 1982-05-15
CA1140930A (en) 1983-02-08
EP0014996B1 (de) 1982-04-28
US4277470A (en) 1981-07-07
ES488703A1 (es) 1980-09-16
IL59441A0 (en) 1980-05-30
DE2907070A1 (de) 1980-09-04
JPS55120563A (en) 1980-09-17
DK77280A (da) 1980-08-24

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